Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01923:Tmem263'

180159

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Tmem263

Ensembl Gene

ENSMUSG00000060935

Gene Name

transmembrane protein 263

Synonyms

AI597468

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL01923

Quality Score

Status

Chromosome

Chromosomal Location

84938491-84953611 bp(+) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 84950295 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Stop codon at position 29 (Q29*)

Ref Sequence

ENSEMBL: ENSMUSP00000149447 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095383] [ENSMUST00000216771]

AlphaFold

Q9DAM7

Predicted Effect

probably null
Transcript: ENSMUST00000095383
AA Change: Q29*

SMART Domains

Protein: ENSMUSP00000093030
Gene: ENSMUSG00000060935
AA Change: Q29*

Domain	Start	End	E-Value	Type
Pfam:UPF0444	24	114	1.7e-48	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000216771
AA Change: Q29*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 40 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrd1	T	A	5: 129,255,143 (GRCm39)	S597T	possibly damaging	Het
Btnl9	T	C	11: 49,071,409 (GRCm39)	D138G	probably benign	Het
Cep135	T	A	5: 76,788,829 (GRCm39)	*1141K	probably null	Het
Ctnnd2	A	T	15: 30,480,974 (GRCm39)	Q74L	probably damaging	Het
Cyp2j13	A	T	4: 95,950,294 (GRCm39)	W236R	probably benign	Het
Dixdc1	A	T	9: 50,606,803 (GRCm39)	I271N	possibly damaging	Het
Dlec1	A	G	9: 118,957,182 (GRCm39)		probably null	Het
Dnah9	C	A	11: 66,016,061 (GRCm39)		probably benign	Het
Dop1a	A	T	9: 86,404,920 (GRCm39)	Y275F	probably damaging	Het
Dysf	T	A	6: 84,187,811 (GRCm39)	*2105R	probably null	Het
Eif4a1	A	T	11: 69,563,129 (GRCm39)	D25E	possibly damaging	Het
Fras1	T	A	5: 96,883,139 (GRCm39)	I2557N	probably damaging	Het
Gm10717	C	T	9: 3,025,616 (GRCm39)	S67L	probably benign	Het
Gm12253	G	T	11: 58,325,727 (GRCm39)		probably null	Het
Gm21738	G	A	14: 19,416,979 (GRCm38)	S144L	probably benign	Het
Hsd17b7	A	G	1: 169,787,035 (GRCm39)	V254A	probably benign	Het
Kif21a	T	A	15: 90,840,633 (GRCm39)	D143V	probably damaging	Het
Lrrc9	T	C	12: 72,557,186 (GRCm39)	V1417A	possibly damaging	Het
Macf1	C	T	4: 123,274,237 (GRCm39)	A4926T	possibly damaging	Het
Mef2a	A	C	7: 66,914,620 (GRCm39)	S91R	probably damaging	Het
Myh7	A	G	14: 55,222,916 (GRCm39)		probably null	Het
Or6c65	T	A	10: 129,603,973 (GRCm39)	F203I	probably benign	Het
Pbx2	A	G	17: 34,813,024 (GRCm39)	D160G	probably damaging	Het
Pcdhb17	T	C	18: 37,619,790 (GRCm39)	F527L	probably benign	Het
Ppm1b	T	C	17: 85,301,489 (GRCm39)	L123P	probably damaging	Het
Ppm1k	T	A	6: 57,499,813 (GRCm39)	K154N	probably benign	Het
Ppp2r1a	T	G	17: 21,185,731 (GRCm39)	*590G	probably null	Het
Raver1	A	T	9: 20,990,536 (GRCm39)	L589Q	probably damaging	Het
Rrbp1	A	G	2: 143,832,081 (GRCm39)	S29P	probably damaging	Het
Senp5	A	G	16: 31,784,634 (GRCm39)	Y673H	probably damaging	Het
Serpina3j	T	A	12: 104,281,473 (GRCm39)		probably benign	Het
Serpinc1	A	G	1: 160,817,116 (GRCm39)	E70G	probably damaging	Het
Sp140l2	A	G	1: 85,231,907 (GRCm39)		probably benign	Het
Stag3	A	G	5: 138,287,492 (GRCm39)	Q139R	probably damaging	Het
Sva	T	A	6: 42,019,104 (GRCm39)	H91Q	probably benign	Het
Tpp1	T	C	7: 105,400,857 (GRCm39)	N57D	probably benign	Het
Vmn2r129	C	T	4: 156,690,549 (GRCm39)		noncoding transcript	Het
Vmn2r27	T	A	6: 124,177,484 (GRCm39)	I507L	probably benign	Het
Wdr11	A	T	7: 129,234,046 (GRCm39)		probably null	Het
Zfp236	C	T	18: 82,700,344 (GRCm39)	E42K	probably damaging	Het

Other mutations in Tmem263

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02010:Tmem263	APN	10	84,950,274 (GRCm39)	missense	probably benign	0.07
IGL02860:Tmem263	APN	10	84,950,416 (GRCm39)	missense	probably damaging	1.00
R7299:Tmem263	UTSW	10	84,950,261 (GRCm39)	splice site	probably null
R8272:Tmem263	UTSW	10	84,950,431 (GRCm39)	missense	possibly damaging	0.92

Posted On

2014-05-07