Incidental Mutation 'IGL01930:Trappc13'
ID180419
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Trappc13
Ensembl Gene ENSMUSG00000021711
Gene Nametrafficking protein particle complex 13
Synonyms2410002O22Rik, 2610524F24Rik
Accession Numbers
Is this an essential gene? Probably essential (E-score: 0.855) question?
Stock #IGL01930
Quality Score
Status
Chromosome13
Chromosomal Location104142149-104178469 bp(-) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 104148078 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000136986 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000022224] [ENSMUST00000141557] [ENSMUST00000144060] [ENSMUST00000179891]
Predicted Effect probably benign
Transcript: ENSMUST00000022224
SMART Domains Protein: ENSMUSP00000022224
Gene: ENSMUSG00000021711

DomainStartEndE-ValueType
Pfam:DUF974 65 298 1.3e-87 PFAM
low complexity region 366 388 N/A INTRINSIC
low complexity region 405 418 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000141557
SMART Domains Protein: ENSMUSP00000118316
Gene: ENSMUSG00000021711

DomainStartEndE-ValueType
Pfam:DUF974 65 299 1.6e-88 PFAM
low complexity region 365 387 N/A INTRINSIC
low complexity region 404 417 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000144060
SMART Domains Protein: ENSMUSP00000114406
Gene: ENSMUSG00000021711

DomainStartEndE-ValueType
Pfam:DUF974 65 293 4.4e-87 PFAM
low complexity region 360 382 N/A INTRINSIC
low complexity region 399 412 N/A INTRINSIC
Predicted Effect probably benign
Transcript: ENSMUST00000179891
SMART Domains Protein: ENSMUSP00000136986
Gene: ENSMUSG00000021711

DomainStartEndE-ValueType
Pfam:DUF974 65 299 1e-87 PFAM
low complexity region 366 388 N/A INTRINSIC
low complexity region 405 418 N/A INTRINSIC
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 27 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
1810011H11Rik G A 14: 32,816,857 E92K probably benign Het
4930433N12Rik C T 9: 3,134,875 noncoding transcript Het
Acsf3 A G 8: 122,780,346 Y126C probably benign Het
Akr1c20 T A 13: 4,507,648 probably benign Het
Cdan1 T C 2: 120,726,582 probably benign Het
Cdc42bpg C T 19: 6,311,368 A308V probably damaging Het
Dek T C 13: 47,088,135 I318V probably benign Het
Dvl1 A G 4: 155,856,188 M422V possibly damaging Het
Erbin G A 13: 103,841,172 L626F probably damaging Het
Fa2h A T 8: 111,349,304 V229E possibly damaging Het
Gfpt1 T A 6: 87,059,415 H193Q possibly damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gpr162 A G 6: 124,861,612 L25P possibly damaging Het
Hsd3b5 T C 3: 98,622,159 T52A probably benign Het
Megf8 T A 7: 25,334,861 V668D probably damaging Het
Olfr418 T C 1: 173,270,610 V145A probably benign Het
Prkdc A G 16: 15,698,887 T1042A probably damaging Het
Rasgrf2 A G 13: 91,982,738 S735P probably damaging Het
Serpina3n T A 12: 104,408,972 L101H probably damaging Het
Sipa1l2 T C 8: 125,419,239 D1674G probably damaging Het
Sval3 A G 6: 41,972,521 N98D probably benign Het
Tbc1d16 G A 11: 119,156,075 R449C possibly damaging Het
Tm7sf3 A C 6: 146,610,933 I321S possibly damaging Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Wdr60 A G 12: 116,225,963 probably null Het
Wdr76 A G 2: 121,510,822 D116G possibly damaging Het
Zscan18 T C 7: 12,775,348 probably benign Het
Other mutations in Trappc13
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00826:Trappc13 APN 13 104144508 missense probably benign 0.30
IGL02637:Trappc13 APN 13 104150062 missense probably benign 0.00
R0470:Trappc13 UTSW 13 104161004 missense possibly damaging 0.51
R0620:Trappc13 UTSW 13 104161081 missense probably damaging 1.00
R0628:Trappc13 UTSW 13 104154916 splice site probably benign
R1402:Trappc13 UTSW 13 104150116 missense probably damaging 1.00
R1402:Trappc13 UTSW 13 104150116 missense probably damaging 1.00
R1530:Trappc13 UTSW 13 104150143 missense probably damaging 1.00
R1826:Trappc13 UTSW 13 104169819 critical splice donor site probably null
R1951:Trappc13 UTSW 13 104174642 missense probably benign 0.43
R3755:Trappc13 UTSW 13 104168560 missense probably benign
R3756:Trappc13 UTSW 13 104168560 missense probably benign
R3918:Trappc13 UTSW 13 104161082 missense probably damaging 1.00
R4704:Trappc13 UTSW 13 104166821 intron probably benign
R4916:Trappc13 UTSW 13 104154294 critical splice donor site probably null
R5590:Trappc13 UTSW 13 104148241 missense probably damaging 1.00
R5635:Trappc13 UTSW 13 104150098 missense probably benign 0.01
R6862:Trappc13 UTSW 13 104150152 missense probably damaging 1.00
Posted On2014-05-07