Incidental Mutation 'R0063:Lama3'
ID 18069
Institutional Source Beutler Lab
Gene Symbol Lama3
Ensembl Gene ENSMUSG00000024421
Gene Name laminin, alpha 3
Synonyms [a]3B, nicein, 150kDa
MMRRC Submission 038355-MU
Accession Numbers
Essential gene? Essential (E-score: 1.000) question?
Stock # R0063 (G1)
Quality Score
Status Validated
Chromosome 18
Chromosomal Location 12333819-12583013 bp(+) (GRCm38)
Type of Mutation splice site
DNA Base Change (assembly) T to C at 12528705 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000140104 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000092070] [ENSMUST00000188815]
AlphaFold no structure available at present
Predicted Effect probably benign
Transcript: ENSMUST00000092070
SMART Domains Protein: ENSMUSP00000089703
Gene: ENSMUSG00000024421

DomainStartEndE-ValueType
signal peptide 1 31 N/A INTRINSIC
LamNT 38 294 1.46e-153 SMART
EGF_Lam 296 350 1.39e-4 SMART
EGF_Lam 353 420 2.66e-10 SMART
EGF_Lam 423 464 3.51e-10 SMART
EGF_Lam 488 530 1.73e-9 SMART
EGF_Lam 533 576 3.81e-11 SMART
EGF_like 579 625 1.82e-1 SMART
EGF_Lam 628 678 5.15e-8 SMART
EGF_Lam 681 725 3.54e-6 SMART
low complexity region 768 781 N/A INTRINSIC
EGF_Lam 1263 1306 3.15e-12 SMART
EGF_Lam 1309 1350 6.3e-3 SMART
EGF_Lam 1353 1399 1.49e-13 SMART
EGF_Lam 1402 1450 8.18e-11 SMART
LamB 1509 1638 4.34e-55 SMART
Pfam:Laminin_EGF 1647 1681 7.9e-5 PFAM
EGF_Lam 1684 1728 2.66e-10 SMART
EGF_Lam 1731 1781 7.81e-8 SMART
Pfam:Laminin_I 1836 2102 2.7e-93 PFAM
low complexity region 2185 2200 N/A INTRINSIC
coiled coil region 2211 2238 N/A INTRINSIC
LamG 2406 2566 1.67e-2 SMART
LamG 2614 2742 1.72e-17 SMART
LamG 2785 2900 3.96e-17 SMART
LamG 3005 3133 1.12e-34 SMART
LamG 3175 3308 3.41e-30 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000188815
SMART Domains Protein: ENSMUSP00000140104
Gene: ENSMUSG00000024421

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
EGF_Lam 78 122 2.66e-10 SMART
EGF_Lam 125 175 7.81e-8 SMART
Pfam:Laminin_I 230 496 1e-90 PFAM
low complexity region 579 594 N/A INTRINSIC
coiled coil region 605 632 N/A INTRINSIC
LamG 800 960 1.67e-2 SMART
LamG 1008 1136 1.72e-17 SMART
LamG 1179 1294 3.96e-17 SMART
LamG 1399 1527 1.12e-34 SMART
LamG 1569 1702 3.41e-30 SMART
Coding Region Coverage
  • 1x: 89.1%
  • 3x: 86.1%
  • 10x: 78.0%
  • 20x: 64.7%
Validation Efficiency 99% (86/87)
MGI Phenotype FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
PHENOTYPE: Mice homozygous for a targeted null mutation develop a lethal blistering phenotype similar to human junctional epidermolysis bullosa, and die 2-3 days after birth from a failure to thrive. [provided by MGI curators]
Allele List at MGI
Other mutations in this stock
Total: 45 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930562C15Rik C T 16: 4,861,048 (GRCm38) R245* probably null Het
4930563I02Rik T A 14: 60,096,028 (GRCm38) probably benign Het
9330182L06Rik T C 5: 9,440,709 (GRCm38) probably benign Het
Acss1 T C 2: 150,627,292 (GRCm38) T435A probably damaging Het
Aoc2 T A 11: 101,326,071 (GRCm38) S327T probably damaging Het
Arid5a T A 1: 36,318,564 (GRCm38) Y252N probably damaging Het
AU040320 T C 4: 126,839,672 (GRCm38) Y662H probably damaging Het
Bcam C T 7: 19,766,848 (GRCm38) V134I probably benign Het
Btbd16 A T 7: 130,823,166 (GRCm38) T426S probably benign Het
Cap2 T C 13: 46,638,032 (GRCm38) probably benign Het
Capn8 T A 1: 182,602,112 (GRCm38) D299E probably damaging Het
Cdipt G A 7: 126,979,600 (GRCm38) V160I probably benign Het
Cyb5r3 T C 15: 83,161,936 (GRCm38) T60A probably benign Het
Dazl T C 17: 152,705,859 (NCBIm37) T212A probably damaging Het
Dgkb T G 12: 38,604,113 (GRCm38) S744A probably benign Het
Dock2 T A 11: 34,756,284 (GRCm38) probably null Het
Ece2 A G 16: 20,642,317 (GRCm38) T442A probably benign Het
Emid1 A T 11: 5,139,704 (GRCm38) probably benign Het
Eml3 C A 19: 8,938,478 (GRCm38) A644D probably damaging Het
Foxp1 A G 6: 98,944,723 (GRCm38) probably benign Het
Ints8 T C 4: 11,252,857 (GRCm38) N75S probably damaging Het
Irs1 T A 1: 82,288,859 (GRCm38) E545D probably damaging Het
Nat8f2 A T 6: 85,867,833 (GRCm38) S182R possibly damaging Het
Nrcam G T 12: 44,550,028 (GRCm38) V343F possibly damaging Het
Pdk2 T C 11: 95,032,480 (GRCm38) H106R probably benign Het
Pkhd1 G A 1: 20,211,950 (GRCm38) T2889I probably benign Het
Pkhd1l1 T A 15: 44,529,237 (GRCm38) L1656H probably damaging Het
Plxna2 A T 1: 194,644,939 (GRCm38) T394S probably benign Het
Pnpla8 T A 12: 44,282,832 (GRCm38) C56S probably damaging Het
Prdm8 G T 5: 98,184,594 (GRCm38) R118L probably damaging Het
Prkce T C 17: 86,482,111 (GRCm38) probably benign Het
Ptprk T A 10: 28,263,767 (GRCm38) Y163N probably damaging Het
Rbbp8 T A 18: 11,734,557 (GRCm38) probably benign Het
Sephs1 A G 2: 4,899,560 (GRCm38) T250A probably benign Het
Slc2a2 T C 3: 28,717,440 (GRCm38) M173T probably damaging Het
Slc2a8 T A 2: 32,979,999 (GRCm38) probably null Het
Tmem131 C T 1: 36,819,128 (GRCm38) V713I probably benign Het
Tmem89 A G 9: 108,914,812 (GRCm38) N60S probably benign Het
Trio G T 15: 27,881,437 (GRCm38) probably benign Het
Tulp2 T C 7: 45,520,860 (GRCm38) probably benign Het
Uggt2 A G 14: 119,007,130 (GRCm38) probably benign Het
Vwa8 A G 14: 79,164,216 (GRCm38) probably benign Het
Xirp2 A G 2: 67,509,083 (GRCm38) D556G probably damaging Het
Xrn1 T C 9: 95,969,535 (GRCm38) L202P probably damaging Het
Zfp354a A T 11: 51,069,571 (GRCm38) H203L probably damaging Het
Other mutations in Lama3
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00091:Lama3 APN 18 12,580,292 (GRCm38) missense probably benign
IGL00272:Lama3 APN 18 12,491,548 (GRCm38) missense probably damaging 1.00
IGL00335:Lama3 APN 18 12,449,588 (GRCm38) splice site probably benign
IGL00836:Lama3 APN 18 12,472,228 (GRCm38) missense probably benign 0.01
IGL01017:Lama3 APN 18 12,441,143 (GRCm38) critical splice donor site probably null
IGL01025:Lama3 APN 18 12,481,037 (GRCm38) missense probably benign 0.09
IGL01394:Lama3 APN 18 12,531,926 (GRCm38) missense probably null 0.39
IGL01545:Lama3 APN 18 12,441,131 (GRCm38) missense probably benign 0.01
IGL01685:Lama3 APN 18 12,453,880 (GRCm38) splice site probably benign
IGL01863:Lama3 APN 18 12,419,936 (GRCm38) splice site probably benign
IGL01869:Lama3 APN 18 12,524,763 (GRCm38) missense possibly damaging 0.94
IGL01894:Lama3 APN 18 12,572,064 (GRCm38) missense probably benign 0.09
IGL02027:Lama3 APN 18 12,516,513 (GRCm38) missense probably damaging 1.00
IGL02106:Lama3 APN 18 12,468,314 (GRCm38) missense probably damaging 0.98
IGL02307:Lama3 APN 18 12,581,783 (GRCm38) missense probably benign 0.09
IGL02342:Lama3 APN 18 12,491,476 (GRCm38) missense probably damaging 1.00
IGL02377:Lama3 APN 18 12,556,750 (GRCm38) missense possibly damaging 0.49
IGL02401:Lama3 APN 18 12,557,727 (GRCm38) missense probably benign 0.02
IGL02517:Lama3 APN 18 12,537,858 (GRCm38) critical splice donor site probably null
IGL02644:Lama3 APN 18 12,525,853 (GRCm38) missense probably benign 0.12
IGL02733:Lama3 APN 18 12,578,127 (GRCm38) missense probably damaging 0.99
IGL02932:Lama3 APN 18 12,528,801 (GRCm38) missense probably damaging 1.00
IGL03006:Lama3 APN 18 12,468,368 (GRCm38) splice site probably benign
IGL03038:Lama3 APN 18 12,419,250 (GRCm38) missense probably damaging 0.99
IGL03064:Lama3 APN 18 12,439,349 (GRCm38) missense possibly damaging 0.72
IGL03146:Lama3 APN 18 12,527,624 (GRCm38) missense possibly damaging 0.66
IGL03233:Lama3 APN 18 12,481,038 (GRCm38) missense probably damaging 1.00
IGL03255:Lama3 APN 18 12,539,703 (GRCm38) missense probably damaging 1.00
IGL03369:Lama3 APN 18 12,553,283 (GRCm38) missense probably benign 0.05
IGL03412:Lama3 APN 18 12,419,182 (GRCm38) missense probably damaging 0.99
IGL02980:Lama3 UTSW 18 12,553,231 (GRCm38) missense probably benign 0.01
IGL03014:Lama3 UTSW 18 12,539,967 (GRCm38) missense possibly damaging 0.95
R0007:Lama3 UTSW 18 12,497,881 (GRCm38) splice site probably benign
R0007:Lama3 UTSW 18 12,497,881 (GRCm38) splice site probably benign
R0050:Lama3 UTSW 18 12,404,103 (GRCm38) missense probably damaging 1.00
R0050:Lama3 UTSW 18 12,404,103 (GRCm38) missense probably damaging 1.00
R0063:Lama3 UTSW 18 12,528,705 (GRCm38) splice site probably benign
R0106:Lama3 UTSW 18 12,403,982 (GRCm38) missense probably damaging 0.96
R0148:Lama3 UTSW 18 12,448,272 (GRCm38) missense probably damaging 1.00
R0165:Lama3 UTSW 18 12,524,810 (GRCm38) missense probably damaging 0.99
R0240:Lama3 UTSW 18 12,539,823 (GRCm38) splice site probably null
R0240:Lama3 UTSW 18 12,539,823 (GRCm38) splice site probably null
R0316:Lama3 UTSW 18 12,519,877 (GRCm38) missense probably benign 0.09
R0325:Lama3 UTSW 18 12,482,126 (GRCm38) missense probably damaging 1.00
R0365:Lama3 UTSW 18 12,507,007 (GRCm38) missense probably damaging 0.96
R0390:Lama3 UTSW 18 12,407,563 (GRCm38) missense probably benign 0.10
R0408:Lama3 UTSW 18 12,456,837 (GRCm38) missense probably benign
R0449:Lama3 UTSW 18 12,500,512 (GRCm38) splice site probably null
R0453:Lama3 UTSW 18 12,465,478 (GRCm38) missense possibly damaging 0.63
R0480:Lama3 UTSW 18 12,450,424 (GRCm38) missense possibly damaging 0.81
R0536:Lama3 UTSW 18 12,525,894 (GRCm38) missense probably damaging 1.00
R0545:Lama3 UTSW 18 12,561,701 (GRCm38) missense possibly damaging 0.90
R0567:Lama3 UTSW 18 12,549,252 (GRCm38) missense probably benign
R0605:Lama3 UTSW 18 12,506,949 (GRCm38) missense probably benign 0.02
R0617:Lama3 UTSW 18 12,419,258 (GRCm38) critical splice donor site probably null
R0629:Lama3 UTSW 18 12,419,245 (GRCm38) missense possibly damaging 0.79
R0671:Lama3 UTSW 18 12,477,590 (GRCm38) missense possibly damaging 0.80
R0730:Lama3 UTSW 18 12,456,850 (GRCm38) splice site probably benign
R1216:Lama3 UTSW 18 12,421,134 (GRCm38) splice site probably benign
R1356:Lama3 UTSW 18 12,500,577 (GRCm38) unclassified probably benign
R1386:Lama3 UTSW 18 12,477,370 (GRCm38) missense probably benign 0.04
R1424:Lama3 UTSW 18 12,519,991 (GRCm38) missense probably benign 0.13
R1426:Lama3 UTSW 18 12,481,098 (GRCm38) critical splice donor site probably null
R1437:Lama3 UTSW 18 12,549,227 (GRCm38) missense possibly damaging 0.46
R1468:Lama3 UTSW 18 12,441,107 (GRCm38) missense probably benign 0.00
R1468:Lama3 UTSW 18 12,441,107 (GRCm38) missense probably benign 0.00
R1472:Lama3 UTSW 18 12,482,045 (GRCm38) missense probably benign 0.23
R1557:Lama3 UTSW 18 12,513,731 (GRCm38) splice site probably benign
R1571:Lama3 UTSW 18 12,539,717 (GRCm38) missense probably damaging 0.98
R1599:Lama3 UTSW 18 12,450,400 (GRCm38) nonsense probably null
R1631:Lama3 UTSW 18 12,407,494 (GRCm38) missense probably damaging 1.00
R1647:Lama3 UTSW 18 12,532,199 (GRCm38) missense possibly damaging 0.90
R1648:Lama3 UTSW 18 12,532,199 (GRCm38) missense possibly damaging 0.90
R1719:Lama3 UTSW 18 12,479,872 (GRCm38) critical splice donor site probably null
R1757:Lama3 UTSW 18 12,465,499 (GRCm38) missense probably benign 0.10
R1766:Lama3 UTSW 18 12,402,062 (GRCm38) missense probably damaging 1.00
R1853:Lama3 UTSW 18 12,513,705 (GRCm38) missense possibly damaging 0.75
R1856:Lama3 UTSW 18 12,537,781 (GRCm38) nonsense probably null
R1909:Lama3 UTSW 18 12,581,798 (GRCm38) missense probably benign 0.19
R1913:Lama3 UTSW 18 12,495,279 (GRCm38) missense probably benign 0.15
R1975:Lama3 UTSW 18 12,453,863 (GRCm38) missense probably damaging 1.00
R2014:Lama3 UTSW 18 12,524,721 (GRCm38) splice site probably benign
R2059:Lama3 UTSW 18 12,528,333 (GRCm38) missense probably damaging 0.98
R2060:Lama3 UTSW 18 12,528,726 (GRCm38) missense probably benign 0.30
R2086:Lama3 UTSW 18 12,524,830 (GRCm38) missense probably benign 0.39
R2115:Lama3 UTSW 18 12,402,849 (GRCm38) missense possibly damaging 0.94
R2291:Lama3 UTSW 18 12,525,079 (GRCm38) missense probably damaging 0.98
R2860:Lama3 UTSW 18 12,453,750 (GRCm38) missense probably damaging 1.00
R2861:Lama3 UTSW 18 12,453,750 (GRCm38) missense probably damaging 1.00
R2862:Lama3 UTSW 18 12,453,750 (GRCm38) missense probably damaging 1.00
R3410:Lama3 UTSW 18 12,413,858 (GRCm38) critical splice donor site probably null
R3614:Lama3 UTSW 18 12,448,288 (GRCm38) missense probably benign 0.03
R3696:Lama3 UTSW 18 12,439,475 (GRCm38) splice site probably benign
R3752:Lama3 UTSW 18 12,507,029 (GRCm38) missense probably damaging 1.00
R3967:Lama3 UTSW 18 12,580,341 (GRCm38) missense probably damaging 1.00
R3968:Lama3 UTSW 18 12,580,341 (GRCm38) missense probably damaging 1.00
R3969:Lama3 UTSW 18 12,580,341 (GRCm38) missense probably damaging 1.00
R3970:Lama3 UTSW 18 12,580,341 (GRCm38) missense probably damaging 1.00
R4088:Lama3 UTSW 18 12,504,308 (GRCm38) nonsense probably null
R4118:Lama3 UTSW 18 12,450,431 (GRCm38) missense probably benign 0.01
R4222:Lama3 UTSW 18 12,450,403 (GRCm38) missense probably damaging 1.00
R4223:Lama3 UTSW 18 12,450,403 (GRCm38) missense probably damaging 1.00
R4224:Lama3 UTSW 18 12,450,403 (GRCm38) missense probably damaging 1.00
R4225:Lama3 UTSW 18 12,450,403 (GRCm38) missense probably damaging 1.00
R4367:Lama3 UTSW 18 12,513,690 (GRCm38) missense probably damaging 1.00
R4404:Lama3 UTSW 18 12,582,531 (GRCm38) missense probably benign 0.01
R4424:Lama3 UTSW 18 12,519,872 (GRCm38) nonsense probably null
R4483:Lama3 UTSW 18 12,549,253 (GRCm38) missense probably benign 0.32
R4484:Lama3 UTSW 18 12,481,088 (GRCm38) missense probably benign
R4516:Lama3 UTSW 18 12,495,358 (GRCm38) missense probably damaging 1.00
R4556:Lama3 UTSW 18 12,479,759 (GRCm38) missense possibly damaging 0.63
R4616:Lama3 UTSW 18 12,504,397 (GRCm38) critical splice donor site probably null
R4702:Lama3 UTSW 18 12,578,029 (GRCm38) nonsense probably null
R4704:Lama3 UTSW 18 12,553,223 (GRCm38) missense probably benign 0.08
R4750:Lama3 UTSW 18 12,504,359 (GRCm38) missense probably benign 0.25
R4753:Lama3 UTSW 18 12,482,084 (GRCm38) missense probably damaging 1.00
R4767:Lama3 UTSW 18 12,500,563 (GRCm38) missense probably benign 0.32
R4777:Lama3 UTSW 18 12,413,771 (GRCm38) missense probably damaging 1.00
R4782:Lama3 UTSW 18 12,411,570 (GRCm38) nonsense probably null
R4784:Lama3 UTSW 18 12,449,544 (GRCm38) missense probably benign 0.20
R4816:Lama3 UTSW 18 12,477,604 (GRCm38) missense possibly damaging 0.93
R4833:Lama3 UTSW 18 12,441,131 (GRCm38) missense probably benign 0.01
R4854:Lama3 UTSW 18 12,411,542 (GRCm38) missense probably benign 0.00
R4863:Lama3 UTSW 18 12,498,678 (GRCm38) intron probably benign
R4863:Lama3 UTSW 18 12,539,793 (GRCm38) missense probably damaging 0.99
R4953:Lama3 UTSW 18 12,448,305 (GRCm38) missense probably damaging 1.00
R4974:Lama3 UTSW 18 12,552,826 (GRCm38) missense probably damaging 0.98
R4996:Lama3 UTSW 18 12,518,743 (GRCm38) missense probably benign 0.24
R5049:Lama3 UTSW 18 12,582,611 (GRCm38) missense probably benign 0.19
R5057:Lama3 UTSW 18 12,531,948 (GRCm38) missense probably null 0.82
R5090:Lama3 UTSW 18 12,542,402 (GRCm38) missense possibly damaging 0.94
R5122:Lama3 UTSW 18 12,539,766 (GRCm38) missense possibly damaging 0.53
R5215:Lama3 UTSW 18 12,577,900 (GRCm38) missense probably damaging 1.00
R5245:Lama3 UTSW 18 12,419,893 (GRCm38) missense probably damaging 1.00
R5259:Lama3 UTSW 18 12,465,508 (GRCm38) missense probably damaging 1.00
R5320:Lama3 UTSW 18 12,552,855 (GRCm38) missense probably damaging 0.99
R5377:Lama3 UTSW 18 12,453,746 (GRCm38) missense probably damaging 0.99
R5432:Lama3 UTSW 18 12,572,066 (GRCm38) missense probably damaging 1.00
R5500:Lama3 UTSW 18 12,456,764 (GRCm38) missense possibly damaging 0.93
R5534:Lama3 UTSW 18 12,553,210 (GRCm38) missense probably benign 0.00
R5589:Lama3 UTSW 18 12,472,220 (GRCm38) missense possibly damaging 0.46
R5604:Lama3 UTSW 18 12,439,348 (GRCm38) missense probably benign
R5617:Lama3 UTSW 18 12,498,936 (GRCm38) intron probably benign
R5709:Lama3 UTSW 18 12,539,799 (GRCm38) missense probably damaging 1.00
R5965:Lama3 UTSW 18 12,429,887 (GRCm38) missense possibly damaging 0.67
R6042:Lama3 UTSW 18 12,574,254 (GRCm38) missense probably damaging 1.00
R6065:Lama3 UTSW 18 12,469,928 (GRCm38) missense possibly damaging 0.53
R6085:Lama3 UTSW 18 12,482,099 (GRCm38) missense probably benign 0.01
R6212:Lama3 UTSW 18 12,513,645 (GRCm38) missense probably damaging 1.00
R6268:Lama3 UTSW 18 12,524,737 (GRCm38) missense probably damaging 0.98
R6276:Lama3 UTSW 18 12,506,949 (GRCm38) missense probably benign 0.02
R6366:Lama3 UTSW 18 12,482,137 (GRCm38) missense probably damaging 1.00
R6393:Lama3 UTSW 18 12,479,756 (GRCm38) missense probably benign 0.44
R6493:Lama3 UTSW 18 12,482,148 (GRCm38) critical splice donor site probably null
R6505:Lama3 UTSW 18 12,495,348 (GRCm38) missense probably benign 0.02
R6563:Lama3 UTSW 18 12,537,766 (GRCm38) missense probably damaging 1.00
R6582:Lama3 UTSW 18 12,577,840 (GRCm38) missense probably damaging 1.00
R6585:Lama3 UTSW 18 12,419,257 (GRCm38) critical splice donor site probably null
R6609:Lama3 UTSW 18 12,513,678 (GRCm38) missense probably damaging 0.99
R6656:Lama3 UTSW 18 12,549,226 (GRCm38) missense possibly damaging 0.66
R6833:Lama3 UTSW 18 12,491,548 (GRCm38) missense probably damaging 1.00
R6834:Lama3 UTSW 18 12,491,548 (GRCm38) missense probably damaging 1.00
R7019:Lama3 UTSW 18 12,528,418 (GRCm38) missense probably damaging 0.97
R7026:Lama3 UTSW 18 12,516,548 (GRCm38) missense probably damaging 0.98
R7088:Lama3 UTSW 18 12,582,545 (GRCm38) missense possibly damaging 0.90
R7100:Lama3 UTSW 18 12,582,644 (GRCm38) missense possibly damaging 0.80
R7102:Lama3 UTSW 18 12,552,813 (GRCm38) missense possibly damaging 0.66
R7103:Lama3 UTSW 18 12,531,879 (GRCm38) missense probably benign 0.00
R7121:Lama3 UTSW 18 12,462,782 (GRCm38) missense probably benign 0.06
R7133:Lama3 UTSW 18 12,539,786 (GRCm38) missense probably benign 0.05
R7150:Lama3 UTSW 18 12,468,289 (GRCm38) missense probably damaging 1.00
R7158:Lama3 UTSW 18 12,456,812 (GRCm38) missense probably benign 0.20
R7170:Lama3 UTSW 18 12,404,076 (GRCm38) missense probably benign 0.26
R7216:Lama3 UTSW 18 12,430,000 (GRCm38) missense probably damaging 1.00
R7223:Lama3 UTSW 18 12,582,608 (GRCm38) missense possibly damaging 0.53
R7243:Lama3 UTSW 18 12,419,845 (GRCm38) missense probably damaging 1.00
R7282:Lama3 UTSW 18 12,439,392 (GRCm38) missense probably damaging 0.99
R7337:Lama3 UTSW 18 12,507,040 (GRCm38) splice site probably null
R7442:Lama3 UTSW 18 12,472,181 (GRCm38) critical splice acceptor site probably null
R7487:Lama3 UTSW 18 12,419,237 (GRCm38) missense probably benign
R7604:Lama3 UTSW 18 12,500,493 (GRCm38) missense possibly damaging 0.93
R7609:Lama3 UTSW 18 12,531,834 (GRCm38) critical splice acceptor site probably null
R7650:Lama3 UTSW 18 12,537,838 (GRCm38) missense probably benign 0.01
R7894:Lama3 UTSW 18 12,462,807 (GRCm38) missense probably benign 0.07
R7975:Lama3 UTSW 18 12,537,739 (GRCm38) missense probably damaging 1.00
R8099:Lama3 UTSW 18 12,534,063 (GRCm38) missense probably damaging 0.97
R8168:Lama3 UTSW 18 12,506,942 (GRCm38) missense probably null
R8219:Lama3 UTSW 18 12,439,360 (GRCm38) missense probably benign 0.07
R8227:Lama3 UTSW 18 12,407,551 (GRCm38) missense probably benign
R8229:Lama3 UTSW 18 12,407,551 (GRCm38) missense probably benign
R8298:Lama3 UTSW 18 12,525,853 (GRCm38) missense probably benign 0.12
R8351:Lama3 UTSW 18 12,540,613 (GRCm38) missense probably damaging 1.00
R8364:Lama3 UTSW 18 12,528,347 (GRCm38) missense probably damaging 0.99
R8463:Lama3 UTSW 18 12,449,839 (GRCm38) missense probably damaging 0.96
R8515:Lama3 UTSW 18 12,411,631 (GRCm38) missense probably null 0.01
R8784:Lama3 UTSW 18 12,421,155 (GRCm38) missense probably benign
R8799:Lama3 UTSW 18 12,490,943 (GRCm38) missense probably damaging 0.96
R8874:Lama3 UTSW 18 12,449,586 (GRCm38) critical splice donor site probably null
R8938:Lama3 UTSW 18 12,556,705 (GRCm38) missense probably damaging 1.00
R8967:Lama3 UTSW 18 12,532,039 (GRCm38) missense possibly damaging 0.46
R9039:Lama3 UTSW 18 12,481,063 (GRCm38) nonsense probably null
R9126:Lama3 UTSW 18 12,450,470 (GRCm38) missense probably damaging 1.00
R9200:Lama3 UTSW 18 12,472,240 (GRCm38) missense probably benign 0.00
R9203:Lama3 UTSW 18 12,462,812 (GRCm38) missense probably benign 0.04
R9246:Lama3 UTSW 18 12,577,902 (GRCm38) missense probably damaging 0.99
R9284:Lama3 UTSW 18 12,450,484 (GRCm38) nonsense probably null
R9553:Lama3 UTSW 18 12,429,962 (GRCm38) missense probably damaging 1.00
R9716:Lama3 UTSW 18 12,450,403 (GRCm38) missense probably damaging 1.00
R9734:Lama3 UTSW 18 12,549,263 (GRCm38) missense possibly damaging 0.94
X0019:Lama3 UTSW 18 12,582,574 (GRCm38) missense possibly damaging 0.94
Z1177:Lama3 UTSW 18 12,429,879 (GRCm38) critical splice acceptor site probably null
Posted On 2013-03-25