Incidental Mutation 'IGL01938:Olfr820'
ID180752
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Olfr820
Ensembl Gene ENSMUSG00000048745
Gene Nameolfactory receptor 820
SynonymsGA_x6K02T2PULF-11688441-11689379, MOR116-1
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.065) question?
Stock #IGL01938
Quality Score
Status
Chromosome10
Chromosomal Location130012621-130021286 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) T to A at 130018112 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 250 (Y250*)
Ref Sequence ENSEMBL: ENSMUSP00000150332 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000059244] [ENSMUST00000214917] [ENSMUST00000215791]
Predicted Effect probably null
Transcript: ENSMUST00000059244
AA Change: Y250*
SMART Domains Protein: ENSMUSP00000052995
Gene: ENSMUSG00000048745
AA Change: Y250*

DomainStartEndE-ValueType
Pfam:7tm_4 29 306 1e-47 PFAM
Pfam:7tm_1 39 288 1.8e-21 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000214917
AA Change: Y250*
Predicted Effect probably null
Transcript: ENSMUST00000215791
AA Change: Y250*
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Allele List at MGI
Other mutations in this stock
Total: 36 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
2310003L06Rik C T 5: 87,971,708 T108I probably damaging Het
Adam34 A G 8: 43,651,016 Y531H probably damaging Het
Arhgef10 T A 8: 14,991,062 N1077K probably benign Het
BC034090 G T 1: 155,232,592 probably null Het
C87499 A G 4: 88,629,363 S24P possibly damaging Het
Cachd1 A G 4: 100,974,128 I706V possibly damaging Het
Cebpz A T 17: 78,934,961 C421* probably null Het
Celsr3 T C 9: 108,828,415 V699A probably benign Het
Col5a1 A G 2: 27,996,873 N935S unknown Het
Dnah1 C T 14: 31,283,887 V2312I probably benign Het
Ebf3 T C 7: 137,309,318 T156A probably damaging Het
Ern1 A G 11: 106,411,657 V457A probably benign Het
Fam129a A G 1: 151,689,614 T232A probably benign Het
Flii T C 11: 60,715,116 Y1177C probably damaging Het
Fryl T A 5: 73,122,364 K197M probably damaging Het
Glb1l3 A G 9: 26,818,529 F515S probably damaging Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Kif26b T C 1: 178,916,038 I1233T probably damaging Het
Kptn A G 7: 16,124,789 Y286C probably damaging Het
Lyst A G 13: 13,637,424 N807S possibly damaging Het
Mki67 C T 7: 135,694,330 V2992M probably benign Het
Myocd A G 11: 65,187,088 L627P probably damaging Het
Neto2 A G 8: 85,690,855 I40T probably benign Het
Nipsnap1 C T 11: 4,893,134 H269Y probably benign Het
Nlrp4g G A 9: 124,349,068 noncoding transcript Het
Nup188 A T 2: 30,329,359 R862S probably benign Het
Olfr1 T A 11: 73,395,645 I126F probably damaging Het
Olfr1253 G T 2: 89,752,348 A160D probably benign Het
Pde4c A T 8: 70,749,378 K549N probably damaging Het
Pkd1l3 A G 8: 109,635,301 T992A probably benign Het
Smyd2 A G 1: 189,888,882 V213A probably benign Het
Sult1c2 C T 17: 53,831,926 V208M probably damaging Het
Ush2a T C 1: 188,797,845 L3277P probably damaging Het
Wdr72 T C 9: 74,148,774 V304A probably benign Het
Xrra1 T C 7: 99,879,469 probably null Het
Zscan29 C T 2: 121,166,209 A344T probably benign Het
Other mutations in Olfr820
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01387:Olfr820 APN 10 130017841 missense probably damaging 0.98
IGL02369:Olfr820 APN 10 130017556 missense possibly damaging 0.81
R0378:Olfr820 UTSW 10 130018003 missense probably damaging 1.00
R0437:Olfr820 UTSW 10 130018096 missense probably damaging 1.00
R0648:Olfr820 UTSW 10 130017481 missense probably damaging 1.00
R1891:Olfr820 UTSW 10 130017570 missense probably damaging 1.00
R2187:Olfr820 UTSW 10 130017688 missense probably damaging 1.00
R4190:Olfr820 UTSW 10 130017978 missense probably damaging 0.96
R4730:Olfr820 UTSW 10 130017547 missense probably damaging 1.00
R6380:Olfr820 UTSW 10 130017913 missense probably benign 0.18
R6496:Olfr820 UTSW 10 130017579 missense probably benign 0.13
R7198:Olfr820 UTSW 10 130017891 missense probably damaging 1.00
R7667:Olfr820 UTSW 10 130017534 missense probably damaging 1.00
R7762:Olfr820 UTSW 10 130017181 intron probably benign
R7823:Olfr820 UTSW 10 130018267 missense probably benign 0.00
Z1177:Olfr820 UTSW 10 130017985 missense probably damaging 1.00
Posted On2014-05-07