Incidental Mutation 'IGL01949:Stk-ps2'
ID181012
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Stk-ps2
Ensembl Gene ENSMUSG00000044457
Gene Nameserine/threonine kinase 2
SynonymsGm4776
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.088) question?
Stock #IGL01949
Quality Score
Status
Chromosome1
Chromosomal Location46020072-46030469 bp(-) (GRCm38)
Type of Mutationexon
DNA Base Change (assembly) A to G at 46029988 bp
ZygosityHeterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
Predicted Effect noncoding transcript
Transcript: ENSMUST00000051224
SMART Domains Protein: ENSMUSP00000054781
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000167676
SMART Domains Protein: ENSMUSP00000133145
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000171707
SMART Domains Protein: ENSMUSP00000125766
Gene: ENSMUSG00000044457

DomainStartEndE-ValueType
S_TKc 14 262 5.9e-85 SMART
UBA 276 313 8.44e-4 SMART
low complexity region 335 349 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000187808
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adamts20 C A 15: 94,326,106 R1247L probably benign Het
Atp2a3 T A 11: 72,981,897 M757K probably damaging Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
D430042O09Rik G A 7: 125,761,842 W108* probably null Het
Dusp5 T C 19: 53,537,473 I182T probably damaging Het
Fuca1 T A 4: 135,923,109 probably benign Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21738 G A 14: 19,416,979 S144L probably benign Het
Hap1 G T 11: 100,348,762 D610E probably damaging Het
Hoxa6 T A 6: 52,206,531 Y178F possibly damaging Het
Ighmbp2 A C 19: 3,265,538 D627E probably benign Het
Itgae T C 11: 73,118,184 I497T probably benign Het
Kbtbd3 A G 9: 4,331,066 D480G possibly damaging Het
Kmt2b A T 7: 30,577,161 probably null Het
Krt5 T A 15: 101,710,613 M278L probably benign Het
Krtap4-9 G A 11: 99,785,565 probably benign Het
Myl12a T C 17: 70,996,714 D56G probably benign Het
Olfr117 T C 17: 37,659,466 Y289C probably damaging Het
Pdgfra C A 5: 75,170,665 H310Q probably damaging Het
Pglyrp2 G T 17: 32,416,106 probably null Het
Polk C T 13: 96,483,538 S718N probably benign Het
Ppip5k1 T A 2: 121,337,860 H687L probably benign Het
Pram1 A T 17: 33,641,335 Q292L probably damaging Het
Prodh2 A G 7: 30,509,765 probably null Het
Rgs9 A T 11: 109,259,834 probably null Het
Svep1 C T 4: 58,176,006 G298R probably damaging Het
Troap T C 15: 99,081,221 S341P probably benign Het
Ugt3a2 T C 15: 9,335,729 F12S probably damaging Het
Vmn2r-ps159 C T 4: 156,338,254 noncoding transcript Het
Zfp236 G T 18: 82,624,396 T1123K probably damaging Het
Other mutations in Stk-ps2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01088:Stk-ps2 APN 1 46029850 exon noncoding transcript
IGL01662:Stk-ps2 APN 1 46029362 unclassified noncoding transcript
IGL01859:Stk-ps2 APN 1 46030042 exon noncoding transcript
IGL02338:Stk-ps2 APN 1 46030177 exon noncoding transcript
R0087:Stk-ps2 UTSW 1 46029889 exon noncoding transcript
R0139:Stk-ps2 UTSW 1 46029795 exon noncoding transcript
R0627:Stk-ps2 UTSW 1 46029691 exon noncoding transcript
R3086:Stk-ps2 UTSW 1 46029076 unclassified noncoding transcript
R3763:Stk-ps2 UTSW 1 46029921 exon noncoding transcript
R4817:Stk-ps2 UTSW 1 46028965 unclassified noncoding transcript
R4951:Stk-ps2 UTSW 1 46029442 unclassified noncoding transcript
Posted On2014-05-07