Incidental Mutation 'IGL01951:Gm9833'
ID181023
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm9833
Ensembl Gene ENSMUSG00000049230
Gene Namepredicted gene 9833
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.174) question?
Stock #IGL01951
Quality Score
Status
Chromosome3
Chromosomal Location10088110-10092565 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) G to A at 10089058 bp
ZygosityHeterozygous
Amino Acid Change Valine to Methionine at position 296 (V296M)
Ref Sequence ENSEMBL: ENSMUSP00000058811 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000061419]
Predicted Effect probably damaging
Transcript: ENSMUST00000061419
AA Change: V296M

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
SMART Domains Protein: ENSMUSP00000058811
Gene: ENSMUSG00000049230
AA Change: V296M

DomainStartEndE-ValueType
RRM 92 165 1.84e-22 SMART
low complexity region 198 211 N/A INTRINSIC
RRM 225 297 5.12e-21 SMART
low complexity region 318 335 N/A INTRINSIC
low complexity region 351 376 N/A INTRINSIC
low complexity region 382 410 N/A INTRINSIC
Pfam:RRM_1 459 497 1.3e-7 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000194684
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 43 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4921539E11Rik A G 4: 103,235,668 I152T probably damaging Het
A2m C T 6: 121,667,190 T949I possibly damaging Het
Begain T A 12: 109,033,645 Y605F probably benign Het
C130026I21Rik A G 1: 85,254,186 probably benign Het
Cavin2 A G 1: 51,289,411 E9G possibly damaging Het
Cdh16 A G 8: 104,617,691 V72A probably damaging Het
Dgkd T C 1: 87,916,916 L268P probably damaging Het
Eps8 T A 6: 137,537,671 Y28F possibly damaging Het
Erap1 T C 13: 74,675,295 I816T probably damaging Het
Fli1 A T 9: 32,461,364 F126Y probably damaging Het
Gm10717 C T 9: 3,025,616 S67L probably benign Het
Gm10718 A T 9: 3,025,118 Y194F probably benign Het
Gm21957 A T 7: 125,219,832 noncoding transcript Het
Gm5862 A C 5: 26,022,771 W41G probably benign Het
Hectd1 T A 12: 51,794,497 R618* probably null Het
Homez T C 14: 54,858,176 E25G probably damaging Het
Ifngr1 C A 10: 19,609,454 N400K possibly damaging Het
Lin7a G A 10: 107,412,025 V186I possibly damaging Het
Lpcat2 G T 8: 92,918,047 S448I probably damaging Het
Lrp10 C A 14: 54,468,662 Y436* probably null Het
Myo1f A G 17: 33,598,017 H707R possibly damaging Het
Neurl4 A G 11: 69,909,623 N1147D probably damaging Het
Olfr1272 G T 2: 90,282,007 D189E probably damaging Het
Olfr1414 T C 1: 92,511,131 D299G probably null Het
Pak6 T C 2: 118,693,260 S299P probably benign Het
Panx2 A G 15: 89,068,767 D487G probably damaging Het
Sbspon T C 1: 15,858,934 N211S probably benign Het
Sgsm1 T A 5: 113,286,767 probably benign Het
Slc38a4 T C 15: 97,019,763 Y27C probably benign Het
Sorbs1 A G 19: 40,318,016 probably benign Het
Ssh1 A T 5: 113,966,247 Y35N possibly damaging Het
Stx2 A T 5: 128,992,265 F127L probably damaging Het
Synm A T 7: 67,739,137 I325N probably damaging Het
Szt2 A G 4: 118,376,493 probably benign Het
Tbc1d23 A G 16: 57,186,685 probably benign Het
Tmem50a T C 4: 134,898,428 probably benign Het
Tpx2 T G 2: 152,884,176 L354V probably benign Het
Trafd1 G A 5: 121,374,031 R399C possibly damaging Het
Trem3 C T 17: 48,249,875 R125W probably damaging Het
Ubp1 T A 9: 113,951,618 Y92* probably null Het
Wnk1 T A 6: 119,963,485 T62S probably damaging Het
Zbtb6 T C 2: 37,429,331 E195G probably benign Het
Zc3h15 A G 2: 83,661,485 D306G probably damaging Het
Other mutations in Gm9833
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL03152:Gm9833 APN 3 10088274 missense probably benign 0.00
R0016:Gm9833 UTSW 3 10089319 missense possibly damaging 0.87
R0092:Gm9833 UTSW 3 10088573 missense possibly damaging 0.76
R0636:Gm9833 UTSW 3 10088783 missense possibly damaging 0.94
R1493:Gm9833 UTSW 3 10088884 missense probably damaging 1.00
R1697:Gm9833 UTSW 3 10089553 missense possibly damaging 0.89
R1957:Gm9833 UTSW 3 10089286 missense probably benign 0.42
R3754:Gm9833 UTSW 3 10088515 missense possibly damaging 0.95
R5658:Gm9833 UTSW 3 10088777 missense probably damaging 1.00
R5772:Gm9833 UTSW 3 10088506 missense probably damaging 1.00
R6298:Gm9833 UTSW 3 10089179 missense probably damaging 1.00
R8191:Gm9833 UTSW 3 10088854 missense probably damaging 1.00
X0023:Gm9833 UTSW 3 10088316 missense probably benign 0.01
Posted On2014-05-07