Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01941:Vmn1r196'

181136

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r196

Ensembl Gene

ENSMUSG00000069295

Gene Name

vomeronasal 1 receptor 196

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

IGL01941

Quality Score

Status

Chromosome

Chromosomal Location

22289920-22298360 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

T to A at 22293699 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Cysteine to Stop codon at position 169 (C169*)

Ref Sequence

ENSEMBL: ENSMUSP00000154145 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000091735] [ENSMUST00000226245] [ENSMUST00000227516] [ENSMUST00000228382] [ENSMUST00000228557]

AlphaFold

Q5SVD5

Predicted Effect

probably null
Transcript: ENSMUST00000091735
AA Change: C169*

SMART Domains

Protein: ENSMUSP00000089329
Gene: ENSMUSG00000069295
AA Change: C169*

Domain	Start	End	E-Value	Type
Pfam:V1R	35	297	3.9e-35	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000120610

Predicted Effect

probably null
Transcript: ENSMUST00000226245
AA Change: C92*

Predicted Effect

probably benign
Transcript: ENSMUST00000227516

Predicted Effect

probably null
Transcript: ENSMUST00000228382
AA Change: C169*

Predicted Effect

probably null
Transcript: ENSMUST00000228557
AA Change: C169*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 53 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
9030624G23Rik	A	T	12: 24,044,801	L123Q	probably benign	Het
Abca2	C	T	2: 25,443,095	S1602F	probably benign	Het
Abcc9	C	A	6: 142,605,904	C1191F	probably damaging	Het
Adam3	G	T	8: 24,681,446		probably benign	Het
Aldh1l1	G	T	6: 90,562,695	G202V	probably damaging	Het
Ankrd46	T	C	15: 36,485,937	N57D	possibly damaging	Het
Asic1	A	T	15: 99,699,101	H548L	possibly damaging	Het
Atpaf2	A	G	11: 60,403,898	I233T	probably benign	Het
Ccdc129	A	G	6: 55,968,045	R584G	probably benign	Het
Ccdc185	G	T	1: 182,748,204	Q307K	probably benign	Het
Cep120	T	C	18: 53,723,148	D399G	probably benign	Het
Cnn2	G	A	10: 79,992,554	V122M	probably benign	Het
Dgkd	T	C	1: 87,924,559	S472P	probably damaging	Het
Dock5	A	C	14: 67,812,232	I701S	probably damaging	Het
Efl1	A	G	7: 82,697,976	E570G	probably benign	Het
Eln	G	A	5: 134,718,170		probably benign	Het
Fat2	A	G	11: 55,312,005	V81A	probably benign	Het
Fbxw21	T	G	9: 109,148,156	I162L	probably benign	Het
Fhl2	G	A	1: 43,131,672	Q161*	probably null	Het
Gabrg2	A	G	11: 41,971,721	Y179H	probably damaging	Het
Gm10717	C	T	9: 3,025,616	S67L	probably benign	Het
Gm10718	A	T	9: 3,025,118	Y194F	probably benign	Het
Gm7714	A	G	5: 88,282,442	S66G	probably benign	Het
Grik5	A	T	7: 25,065,182	I152N	probably damaging	Het
H2-Ab1	A	T	17: 34,267,434	K156*	probably null	Het
Hecw1	T	C	13: 14,316,310	Y699C	probably benign	Het
Ipo9	A	C	1: 135,408,073	V202G	possibly damaging	Het
Jmjd6	A	T	11: 116,841,358		probably null	Het
Lama5	A	G	2: 180,192,392	I1416T	possibly damaging	Het
Matn1	T	C	4: 130,952,261		probably benign	Het
Mavs	T	C	2: 131,246,605	V443A	probably damaging	Het
Mpdz	A	T	4: 81,286,387	S1798R	possibly damaging	Het
Muc6	A	C	7: 141,638,584	S2059A	probably benign	Het
Olfr1251	A	T	2: 89,667,468	C139*	probably null	Het
Otud7b	G	T	3: 96,155,459	G672C	probably benign	Het
Palld	T	A	8: 61,535,700	T572S	probably benign	Het
Pde6b	T	A	5: 108,423,036	V379E	probably benign	Het
Peak1	A	G	9: 56,258,775	V623A	probably damaging	Het
Prr12	C	T	7: 45,048,659		probably benign	Het
Rxra	T	C	2: 27,754,241	I315T	probably damaging	Het
Slc11a1	C	T	1: 74,377,179	A55V	probably damaging	Het
Slitrk3	T	C	3: 73,051,071	N123D	possibly damaging	Het
Spcs1	A	G	14: 31,000,872	M82T	probably damaging	Het
Sspo	A	G	6: 48,495,182	E113G	probably benign	Het
Syne2	A	G	12: 75,967,220	K3062E	probably benign	Het
Traf3ip2	T	C	10: 39,634,660	S310P	probably benign	Het
Ubp1	T	C	9: 113,956,758	L167S	probably damaging	Het
Vmn1r223	T	A	13: 23,250,237	F334I	possibly damaging	Het
Vmn2r10	A	T	5: 108,995,954	I710N	probably damaging	Het
Vmn2r-ps159	C	T	4: 156,338,254		noncoding transcript	Het
Wdr26	A	G	1: 181,211,070		probably benign	Het
Wnt7a	A	G	6: 91,394,663	F106L	probably benign	Het
Zfp940	C	T	7: 29,846,870	V34M	probably damaging	Het

Other mutations in Vmn1r196

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0415:Vmn1r196	UTSW	13	22293836	missense	probably damaging	1.00
R0502:Vmn1r196	UTSW	13	22293387	missense	probably benign	0.01
R0503:Vmn1r196	UTSW	13	22293387	missense	probably benign	0.01
R2306:Vmn1r196	UTSW	13	22293303	missense	probably benign	0.08
R4463:Vmn1r196	UTSW	13	22293683	missense	probably benign
R6335:Vmn1r196	UTSW	13	22293717	missense	probably benign	0.18
R7664:Vmn1r196	UTSW	13	22293762	missense	probably damaging	1.00
R8062:Vmn1r196	UTSW	13	22293270	missense	probably damaging	1.00
R9017:Vmn1r196	UTSW	13	22294084	missense	probably benign	0.00
R9434:Vmn1r196	UTSW	13	22293620	nonsense	probably null
R9583:Vmn1r196	UTSW	13	22293750	missense	probably damaging	0.96
S24628:Vmn1r196	UTSW	13	22293836	missense	probably damaging	1.00

Posted On

2014-05-07