Incidental Mutation 'IGL01955:Tas2r113'
ID181409
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Tas2r113
Ensembl Gene ENSMUSG00000056926
Gene Nametaste receptor, type 2, member 113
SynonymsT2R13, mGR13, mt2r58, Tas2r13
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.057) question?
Stock #IGL01955
Quality Score
Status
Chromosome6
Chromosomal Location132893011-132893940 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to T at 132893854 bp
ZygosityHeterozygous
Amino Acid Change Methionine to Leucine at position 282 (M282L)
Ref Sequence ENSEMBL: ENSMUSP00000078044 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000079035]
Predicted Effect probably benign
Transcript: ENSMUST00000079035
AA Change: M282L

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
SMART Domains Protein: ENSMUSP00000078044
Gene: ENSMUSG00000056926
AA Change: M282L

DomainStartEndE-ValueType
Pfam:TAS2R 1 301 9.4e-78 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 39 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
4930432E11Rik G T 7: 29,573,995 noncoding transcript Het
Abcc1 T A 16: 14,410,795 I302N probably damaging Het
Abhd16a A G 17: 35,101,340 S394G probably damaging Het
Adgrv1 T C 13: 81,182,783 Y71C probably damaging Het
Apol8 A G 15: 77,749,699 C226R probably benign Het
Armc4 C T 18: 7,127,291 R974Q possibly damaging Het
Bbs7 A G 3: 36,610,322 S45P probably benign Het
Cacna1b T C 2: 24,639,137 Y1575C probably damaging Het
Cckbr T A 7: 105,434,962 V301E probably damaging Het
Cwc27 A G 13: 104,807,737 Y79H probably damaging Het
Dchs1 T C 7: 105,757,591 T2236A probably benign Het
Ddx50 T C 10: 62,647,183 R36G probably benign Het
Extl3 T A 14: 65,075,966 Y589F probably benign Het
Gab2 T C 7: 97,304,223 V601A probably damaging Het
Hsd3b1 T A 3: 98,853,147 N176I probably benign Het
L3mbtl3 A T 10: 26,318,438 S420R unknown Het
Olfr1000 A G 2: 85,608,707 F68L probably benign Het
Olfr319 T C 11: 58,702,129 S143P probably damaging Het
Olfr589 T A 7: 103,154,854 K298* probably null Het
Polr2a T C 11: 69,741,848 D974G probably damaging Het
Ptges3l T C 11: 101,423,818 K13E possibly damaging Het
Ptprk A G 10: 28,595,865 probably benign Het
Rassf3 T C 10: 121,417,122 Y60C probably damaging Het
Rnf157 T C 11: 116,359,896 T160A probably damaging Het
Secisbp2l A G 2: 125,743,812 probably null Het
Setd2 A G 9: 110,549,318 T734A probably benign Het
Skint5 A G 4: 113,623,736 probably null Het
Slc38a9 A G 13: 112,695,418 probably benign Het
Snx17 T G 5: 31,197,082 probably benign Het
Tbc1d31 A G 15: 57,942,370 N404D probably benign Het
Tmem63c A T 12: 87,077,208 I487F probably benign Het
Tpm3 A G 3: 90,088,435 M164V probably benign Het
Trafd1 G T 5: 121,375,154 N340K probably benign Het
Trpv4 T A 5: 114,622,682 K863* probably null Het
Ttn A T 2: 76,797,352 M13003K possibly damaging Het
Tulp1 G A 17: 28,356,424 T103M probably damaging Het
Unc5b T C 10: 60,778,255 T272A probably benign Het
Vmn1r82 A C 7: 12,305,723 probably null Het
Zc3h7b A G 15: 81,792,004 N704D probably benign Het
Other mutations in Tas2r113
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00858:Tas2r113 APN 6 132893152 missense probably benign 0.01
IGL01118:Tas2r113 APN 6 132893315 missense probably benign 0.00
IGL01366:Tas2r113 APN 6 132893797 missense probably benign 0.06
IGL02629:Tas2r113 APN 6 132893336 missense probably damaging 1.00
IGL02681:Tas2r113 APN 6 132893367 missense probably damaging 1.00
IGL02883:Tas2r113 APN 6 132893419 missense probably damaging 1.00
R0002:Tas2r113 UTSW 6 132893779 missense probably benign 0.21
R0309:Tas2r113 UTSW 6 132893378 missense probably damaging 1.00
R1700:Tas2r113 UTSW 6 132893792 missense possibly damaging 0.92
R1748:Tas2r113 UTSW 6 132893732 missense probably damaging 0.98
R1854:Tas2r113 UTSW 6 132893329 missense probably damaging 1.00
R1974:Tas2r113 UTSW 6 132893833 missense probably benign 0.00
R4697:Tas2r113 UTSW 6 132893516 missense probably benign 0.04
R4798:Tas2r113 UTSW 6 132893707 missense possibly damaging 0.69
R4816:Tas2r113 UTSW 6 132893782 missense probably benign 0.09
R4906:Tas2r113 UTSW 6 132893558 missense possibly damaging 0.69
R6005:Tas2r113 UTSW 6 132893696 missense probably benign 0.02
R6012:Tas2r113 UTSW 6 132893681 missense probably damaging 1.00
R6107:Tas2r113 UTSW 6 132893014 missense probably damaging 1.00
R6603:Tas2r113 UTSW 6 132893458 missense probably benign 0.01
R7263:Tas2r113 UTSW 6 132893576 missense possibly damaging 0.90
R7434:Tas2r113 UTSW 6 132893309 missense probably benign 0.03
R7759:Tas2r113 UTSW 6 132893927 missense possibly damaging 0.85
X0022:Tas2r113 UTSW 6 132893296 missense probably damaging 0.98
Posted On2014-05-07