Incidental Mutation 'IGL01972:Vmn1r69'
ID181649
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Vmn1r69
Ensembl Gene ENSMUSG00000091662
Gene Namevomeronasal 1 receptor 69
SynonymsV1re9
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.072) question?
Stock #IGL01972
Quality Score
Status
Chromosome7
Chromosomal Location10578930-10613659 bp(-) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) A to T at 10580659 bp
ZygosityHeterozygous
Amino Acid Change Tyrosine to Stop codon at position 48 (Y48*)
Ref Sequence ENSEMBL: ENSMUSP00000154076 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000163658] [ENSMUST00000176284] [ENSMUST00000176707] [ENSMUST00000226160] [ENSMUST00000226190] [ENSMUST00000226228] [ENSMUST00000227853] [ENSMUST00000228296] [ENSMUST00000228478] [ENSMUST00000228638]
Predicted Effect probably null
Transcript: ENSMUST00000163658
AA Change: Y48*
SMART Domains Protein: ENSMUSP00000129646
Gene: ENSMUSG00000091662
AA Change: Y48*

DomainStartEndE-ValueType
Pfam:V1R 50 307 3.3e-32 PFAM
Predicted Effect probably null
Transcript: ENSMUST00000176284
AA Change: Y48*
Predicted Effect probably null
Transcript: ENSMUST00000176707
AA Change: Y48*
Predicted Effect probably null
Transcript: ENSMUST00000226160
AA Change: Y48*
Predicted Effect probably null
Transcript: ENSMUST00000226190
AA Change: Y48*
Predicted Effect probably null
Transcript: ENSMUST00000226228
AA Change: Y48*
Predicted Effect noncoding transcript
Transcript: ENSMUST00000226990
Predicted Effect probably benign
Transcript: ENSMUST00000227853
Predicted Effect probably benign
Transcript: ENSMUST00000228296
Predicted Effect probably benign
Transcript: ENSMUST00000228478
Predicted Effect probably benign
Transcript: ENSMUST00000228638
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahr T G 12: 35,504,449 D557A possibly damaging Het
Akap11 T C 14: 78,507,857 Q1697R probably damaging Het
Alpi T A 1: 87,099,709 T312S probably damaging Het
Cacna1b C A 2: 24,635,095 probably null Het
Car5a C T 8: 121,927,082 probably null Het
Cubn T C 2: 13,446,072 T841A possibly damaging Het
Eml6 A T 11: 29,838,451 F545I possibly damaging Het
Fam114a2 G A 11: 57,509,394 T156I probably damaging Het
Fam160a2 T C 7: 105,390,145 N5S probably damaging Het
Fbxl21 C T 13: 56,536,859 R259* probably null Het
Gm5117 C T 8: 31,737,759 noncoding transcript Het
Hc T C 2: 34,983,772 Y1650C probably damaging Het
Med12l C A 3: 59,261,893 T1568K probably damaging Het
Olfr429 G T 1: 174,089,421 C127F probably damaging Het
Olfr701 A G 7: 106,818,532 I150V probably benign Het
Olfr996 T C 2: 85,579,773 F178S probably damaging Het
Orm3 A G 4: 63,359,326 S184G probably benign Het
Padi1 A G 4: 140,818,859 probably benign Het
Rnf133 T C 6: 23,648,989 T357A probably benign Het
Skiv2l2 T C 13: 112,881,061 K853E probably damaging Het
Tmem17 A G 11: 22,517,265 S60G probably benign Het
Ubqlnl G T 7: 104,149,697 Q198K probably benign Het
Zfp658 G A 7: 43,572,710 W136* probably null Het
Other mutations in Vmn1r69
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00155:Vmn1r69 APN 7 10579952 missense probably benign 0.00
IGL02339:Vmn1r69 APN 7 10580718 nonsense probably null
IGL02424:Vmn1r69 APN 7 10580658 missense probably benign 0.00
IGL02602:Vmn1r69 APN 7 10579974 missense probably benign 0.14
IGL03271:Vmn1r69 APN 7 10580669 missense probably benign 0.11
R0034:Vmn1r69 UTSW 7 10580811 intron probably benign
R0052:Vmn1r69 UTSW 7 10580400 missense probably benign 0.00
R0096:Vmn1r69 UTSW 7 10580058 missense probably damaging 1.00
R0539:Vmn1r69 UTSW 7 10580947 splice site probably benign
R0604:Vmn1r69 UTSW 7 10580654 missense probably benign 0.00
R1681:Vmn1r69 UTSW 7 10580252 missense probably benign 0.06
R1884:Vmn1r69 UTSW 7 10580751 missense probably benign 0.00
R3741:Vmn1r69 UTSW 7 10580142 missense possibly damaging 0.47
R4655:Vmn1r69 UTSW 7 10580099 missense probably benign 0.03
R4735:Vmn1r69 UTSW 7 10580999 utr 5 prime probably benign
R4758:Vmn1r69 UTSW 7 10580546 missense probably benign 0.00
R5582:Vmn1r69 UTSW 7 10580508 missense probably damaging 1.00
R5966:Vmn1r69 UTSW 7 10580790 missense probably benign 0.00
R5977:Vmn1r69 UTSW 7 10580490 missense probably damaging 1.00
R6458:Vmn1r69 UTSW 7 10580438 missense probably benign
R6987:Vmn1r69 UTSW 7 10580564 start codon destroyed probably null 0.99
R7133:Vmn1r69 UTSW 7 10581068 intron probably benign
R7532:Vmn1r69 UTSW 7 10580354 missense probably damaging 0.98
R7878:Vmn1r69 UTSW 7 10580790 missense probably benign 0.00
Z1176:Vmn1r69 UTSW 7 10580096 missense possibly damaging 0.64
Posted On2014-05-07