Incidental Mutation 'IGL01972:Zfp658'
ID181665
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Zfp658
Ensembl Gene ENSMUSG00000056592
Gene Namezinc finger protein 658
Synonyms
Accession Numbers
Is this an essential gene? Non essential (E-score: 0.000) question?
Stock #IGL01972
Quality Score
Status
Chromosome7
Chromosomal Location43562256-43575461 bp(+) (GRCm38)
Type of Mutationnonsense
DNA Base Change (assembly) G to A at 43572710 bp
ZygosityHeterozygous
Amino Acid Change Tryptophan to Stop codon at position 136 (W136*)
Ref Sequence ENSEMBL: ENSMUSP00000103606 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000005597] [ENSMUST00000107972]
Predicted Effect probably null
Transcript: ENSMUST00000005597
AA Change: W136*
SMART Domains Protein: ENSMUSP00000005597
Gene: ENSMUSG00000056592
AA Change: W136*

DomainStartEndE-ValueType
KRAB 23 83 3.7e-27 SMART
ZnF_C2H2 276 295 8.84e1 SMART
ZnF_C2H2 301 323 5.81e-2 SMART
ZnF_C2H2 328 350 1.5e-4 SMART
ZnF_C2H2 356 378 1.84e-4 SMART
ZnF_C2H2 384 406 3.16e-3 SMART
ZnF_C2H2 412 434 1.45e-2 SMART
ZnF_C2H2 440 462 4.87e-4 SMART
ZnF_C2H2 468 490 4.87e-4 SMART
ZnF_C2H2 496 518 6.88e-4 SMART
ZnF_C2H2 524 546 1.69e-3 SMART
ZnF_C2H2 552 574 9.73e-4 SMART
ZnF_C2H2 580 602 1.82e-3 SMART
ZnF_C2H2 608 630 3.16e-3 SMART
ZnF_C2H2 636 658 8.94e-3 SMART
ZnF_C2H2 664 686 3.74e-5 SMART
ZnF_C2H2 692 714 2.99e-4 SMART
ZnF_C2H2 720 742 5.21e-4 SMART
ZnF_C2H2 748 770 2.79e-4 SMART
ZnF_C2H2 776 798 1.58e-3 SMART
ZnF_C2H2 804 826 3.44e-4 SMART
ZnF_C2H2 832 854 5.59e-4 SMART
ZnF_C2H2 860 882 5.81e-2 SMART
Predicted Effect probably null
Transcript: ENSMUST00000107972
AA Change: W136*
SMART Domains Protein: ENSMUSP00000103606
Gene: ENSMUSG00000056592
AA Change: W136*

DomainStartEndE-ValueType
KRAB 23 83 3.7e-27 SMART
ZnF_C2H2 276 295 8.84e1 SMART
ZnF_C2H2 301 323 5.81e-2 SMART
ZnF_C2H2 328 350 1.5e-4 SMART
ZnF_C2H2 356 378 1.84e-4 SMART
ZnF_C2H2 384 406 3.16e-3 SMART
ZnF_C2H2 412 434 1.45e-2 SMART
ZnF_C2H2 440 462 4.87e-4 SMART
ZnF_C2H2 468 490 4.87e-4 SMART
ZnF_C2H2 496 518 6.88e-4 SMART
ZnF_C2H2 524 546 1.69e-3 SMART
ZnF_C2H2 552 574 9.73e-4 SMART
ZnF_C2H2 580 602 1.82e-3 SMART
ZnF_C2H2 608 630 3.16e-3 SMART
ZnF_C2H2 636 658 8.94e-3 SMART
ZnF_C2H2 664 686 3.74e-5 SMART
ZnF_C2H2 692 714 2.99e-4 SMART
ZnF_C2H2 720 742 5.21e-4 SMART
ZnF_C2H2 748 770 2.79e-4 SMART
ZnF_C2H2 776 798 1.58e-3 SMART
ZnF_C2H2 804 826 3.44e-4 SMART
ZnF_C2H2 832 854 5.59e-4 SMART
ZnF_C2H2 860 882 5.81e-2 SMART
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 23 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Ahr T G 12: 35,504,449 D557A possibly damaging Het
Akap11 T C 14: 78,507,857 Q1697R probably damaging Het
Alpi T A 1: 87,099,709 T312S probably damaging Het
Cacna1b C A 2: 24,635,095 probably null Het
Car5a C T 8: 121,927,082 probably null Het
Cubn T C 2: 13,446,072 T841A possibly damaging Het
Eml6 A T 11: 29,838,451 F545I possibly damaging Het
Fam114a2 G A 11: 57,509,394 T156I probably damaging Het
Fam160a2 T C 7: 105,390,145 N5S probably damaging Het
Fbxl21 C T 13: 56,536,859 R259* probably null Het
Gm5117 C T 8: 31,737,759 noncoding transcript Het
Hc T C 2: 34,983,772 Y1650C probably damaging Het
Med12l C A 3: 59,261,893 T1568K probably damaging Het
Olfr429 G T 1: 174,089,421 C127F probably damaging Het
Olfr701 A G 7: 106,818,532 I150V probably benign Het
Olfr996 T C 2: 85,579,773 F178S probably damaging Het
Orm3 A G 4: 63,359,326 S184G probably benign Het
Padi1 A G 4: 140,818,859 probably benign Het
Rnf133 T C 6: 23,648,989 T357A probably benign Het
Skiv2l2 T C 13: 112,881,061 K853E probably damaging Het
Tmem17 A G 11: 22,517,265 S60G probably benign Het
Ubqlnl G T 7: 104,149,697 Q198K probably benign Het
Vmn1r69 A T 7: 10,580,659 Y48* probably null Het
Other mutations in Zfp658
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00465:Zfp658 APN 7 43567356 missense probably benign 0.03
IGL00475:Zfp658 APN 7 43574076 missense possibly damaging 0.68
IGL03223:Zfp658 APN 7 43567311 missense possibly damaging 0.85
R0135:Zfp658 UTSW 7 43573595 nonsense probably null
R1863:Zfp658 UTSW 7 43573899 missense possibly damaging 0.78
R1962:Zfp658 UTSW 7 43573821 missense possibly damaging 0.93
R2698:Zfp658 UTSW 7 43573545 missense possibly damaging 0.53
R3781:Zfp658 UTSW 7 43573846 missense probably benign
R4791:Zfp658 UTSW 7 43574466 missense possibly damaging 0.93
R5392:Zfp658 UTSW 7 43572931 missense probably benign 0.07
R6092:Zfp658 UTSW 7 43574527 missense possibly damaging 0.73
R6594:Zfp658 UTSW 7 43567277 missense possibly damaging 0.86
R7003:Zfp658 UTSW 7 43574748 missense possibly damaging 0.85
R7008:Zfp658 UTSW 7 43573912 missense possibly damaging 0.95
R7077:Zfp658 UTSW 7 43573989 missense probably benign 0.32
R7689:Zfp658 UTSW 7 43574678 missense probably benign 0.00
R7793:Zfp658 UTSW 7 43574684 missense possibly damaging 0.74
R7939:Zfp658 UTSW 7 43574877 missense possibly damaging 0.73
Z1176:Zfp658 UTSW 7 43573217 missense possibly damaging 0.72
Posted On2014-05-07