Incidental Mutation 'IGL01977:Cyp2c29'
ID181747
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Cyp2c29
Ensembl Gene ENSMUSG00000003053
Gene Namecytochrome P450, family 2, subfamily c, polypeptide 29
SynonymsAh-2, Cyp2c, P450-2C, Ahh-1, AHOHase, AHOH
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.102) question?
Stock #IGL01977
Quality Score
Status
Chromosome19
Chromosomal Location39269405-39330713 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) T to C at 39290897 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000135839 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000003137] [ENSMUST00000176624] [ENSMUST00000177087]
Predicted Effect probably benign
Transcript: ENSMUST00000003137
SMART Domains Protein: ENSMUSP00000003137
Gene: ENSMUSG00000003053

DomainStartEndE-ValueType
low complexity region 7 19 N/A INTRINSIC
Pfam:p450 30 487 5.4e-165 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000176624
SMART Domains Protein: ENSMUSP00000135863
Gene: ENSMUSG00000003053

DomainStartEndE-ValueType
Pfam:p450 12 448 2.7e-156 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000177087
SMART Domains Protein: ENSMUSP00000135839
Gene: ENSMUSG00000003053

DomainStartEndE-ValueType
low complexity region 7 19 N/A INTRINSIC
Pfam:p450 30 118 8.4e-22 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 53 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Abca7 T A 10: 80,006,152 S1040T probably benign Het
Adam25 T C 8: 40,755,097 Y467H probably benign Het
Ank1 A G 8: 23,115,433 I1061V probably benign Het
Anxa10 T C 8: 62,076,314 E123G probably damaging Het
Arhgap35 G A 7: 16,563,203 L646F probably damaging Het
Atp8b5 A G 4: 43,320,590 probably null Het
Brap A G 5: 121,678,847 probably benign Het
Carmil3 A G 14: 55,493,536 T87A probably damaging Het
Ccdc172 A G 19: 58,552,877 D256G possibly damaging Het
Cep350 C T 1: 155,911,968 A1375T probably benign Het
Chrdl2 A T 7: 100,022,056 Q127L probably benign Het
Ddi1 C A 9: 6,266,226 V48F probably benign Het
Ddrgk1 C T 2: 130,655,246 probably benign Het
Fastkd1 C T 2: 69,694,588 V626I possibly damaging Het
Fgd5 A G 6: 92,024,562 T755A probably benign Het
Fpgt G T 3: 155,088,018 T124K probably damaging Het
Gnl2 G A 4: 125,047,612 probably null Het
Got1 A T 19: 43,515,845 S46T probably benign Het
Hbb-bt G T 7: 103,813,863 H3N probably benign Het
Ikbke C T 1: 131,272,101 probably benign Het
Il2rb A G 15: 78,481,697 S467P probably benign Het
Kcnma1 A G 14: 23,530,299 probably benign Het
Ltbp2 T C 12: 84,830,199 N391D probably damaging Het
Npr3 A T 15: 11,858,718 I360N probably damaging Het
Nradd G A 9: 110,622,169 P44S possibly damaging Het
Olfr1023 G T 2: 85,887,367 C189F probably damaging Het
Olfr871 G A 9: 20,212,459 V37I possibly damaging Het
Pcdh17 A G 14: 84,533,097 E1005G possibly damaging Het
Pcdhb11 A G 18: 37,422,291 T225A possibly damaging Het
Pja2 T C 17: 64,297,826 D454G probably benign Het
Pon3 T C 6: 5,221,670 Y320C probably damaging Het
Prl2a1 A G 13: 27,806,278 D70G probably damaging Het
Proc T A 18: 32,127,419 T218S probably benign Het
Proz G T 8: 13,066,913 G155V probably damaging Het
Rab11fip3 T C 17: 26,068,003 E392G possibly damaging Het
Rab3gap2 C T 1: 185,267,023 R976* probably null Het
Shisa2 G A 14: 59,629,986 C229Y probably damaging Het
Slc2a5 T C 4: 150,142,218 V379A probably damaging Het
Slc31a2 A T 4: 62,295,960 K47N probably damaging Het
Sult2a6 G A 7: 14,253,486 T88I probably benign Het
Tbc1d14 T C 5: 36,505,037 Y302C probably damaging Het
Thumpd3 C A 6: 113,059,966 N275K possibly damaging Het
Tnks2 T C 19: 36,872,590 probably null Het
Tube1 G A 10: 39,135,045 probably benign Het
Umodl1 T A 17: 30,973,768 Y290N probably damaging Het
Usp34 G A 11: 23,452,661 E726K probably damaging Het
Vmn2r84 T A 10: 130,394,066 D59V probably benign Het
Vps11 T A 9: 44,356,219 probably benign Het
Wdr19 T C 5: 65,228,569 Y631H probably benign Het
Wdr62 G A 7: 30,258,101 H88Y probably damaging Het
Wdr93 A T 7: 79,752,505 N184I probably damaging Het
Wnk4 T A 11: 101,265,414 F473Y probably damaging Het
Zbtb16 A G 9: 48,657,183 W661R probably damaging Het
Other mutations in Cyp2c29
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00420:Cyp2c29 APN 19 39321699 splice site probably benign
IGL00482:Cyp2c29 APN 19 39325023 missense probably damaging 0.97
IGL00694:Cyp2c29 APN 19 39321635 missense possibly damaging 0.64
IGL00836:Cyp2c29 APN 19 39324990 missense probably damaging 0.98
IGL00858:Cyp2c29 APN 19 39307656 missense probably damaging 1.00
IGL01350:Cyp2c29 APN 19 39330327 missense probably damaging 1.00
IGL01455:Cyp2c29 APN 19 39329117 missense possibly damaging 0.89
IGL01718:Cyp2c29 APN 19 39330260 missense possibly damaging 0.48
IGL01991:Cyp2c29 APN 19 39330315 missense probably damaging 1.00
IGL02097:Cyp2c29 APN 19 39307620 missense probably damaging 1.00
IGL02267:Cyp2c29 APN 19 39330422 missense probably benign 0.19
IGL02451:Cyp2c29 APN 19 39290847 missense possibly damaging 0.66
IGL02452:Cyp2c29 APN 19 39290847 missense possibly damaging 0.66
IGL02548:Cyp2c29 APN 19 39290847 missense possibly damaging 0.66
IGL02549:Cyp2c29 APN 19 39309785 missense possibly damaging 0.48
IGL02938:Cyp2c29 APN 19 39287123 missense probably damaging 0.99
IGL03252:Cyp2c29 APN 19 39287175 missense probably damaging 1.00
IGL03367:Cyp2c29 APN 19 39329215 missense probably damaging 0.97
H8562:Cyp2c29 UTSW 19 39309662 missense probably damaging 1.00
IGL03052:Cyp2c29 UTSW 19 39287218 missense possibly damaging 0.90
R0415:Cyp2c29 UTSW 19 39329095 splice site probably benign
R0504:Cyp2c29 UTSW 19 39309780 missense probably benign 0.29
R0690:Cyp2c29 UTSW 19 39309726 missense probably benign 0.00
R1531:Cyp2c29 UTSW 19 39324968 missense probably damaging 1.00
R1730:Cyp2c29 UTSW 19 39324945 missense possibly damaging 0.79
R1981:Cyp2c29 UTSW 19 39307772 splice site probably null
R2113:Cyp2c29 UTSW 19 39330264 missense probably damaging 1.00
R2220:Cyp2c29 UTSW 19 39287232 missense probably benign 0.09
R3873:Cyp2c29 UTSW 19 39329144 missense probably damaging 0.99
R4424:Cyp2c29 UTSW 19 39287176 missense probably damaging 0.98
R4451:Cyp2c29 UTSW 19 39290826 missense probably damaging 0.99
R4803:Cyp2c29 UTSW 19 39324995 missense probably benign 0.01
R5288:Cyp2c29 UTSW 19 39330372 missense probably damaging 0.96
R5474:Cyp2c29 UTSW 19 39324992 missense probably damaging 1.00
R5475:Cyp2c29 UTSW 19 39330287 missense possibly damaging 0.91
R5893:Cyp2c29 UTSW 19 39330389 missense possibly damaging 0.93
R5894:Cyp2c29 UTSW 19 39330389 missense possibly damaging 0.93
R6000:Cyp2c29 UTSW 19 39307606 critical splice acceptor site probably null
R6144:Cyp2c29 UTSW 19 39321609 missense possibly damaging 0.96
R6296:Cyp2c29 UTSW 19 39330261 missense possibly damaging 0.64
R6365:Cyp2c29 UTSW 19 39307754 missense probably damaging 1.00
R6449:Cyp2c29 UTSW 19 39290867 missense probably benign 0.05
R6464:Cyp2c29 UTSW 19 39329225 missense probably damaging 0.96
R6919:Cyp2c29 UTSW 19 39291141 missense probably benign 0.26
R6978:Cyp2c29 UTSW 19 39321663 missense probably damaging 1.00
R7038:Cyp2c29 UTSW 19 39287127 missense probably benign 0.01
R7040:Cyp2c29 UTSW 19 39330337 missense possibly damaging 0.95
R7391:Cyp2c29 UTSW 19 39307767 missense probably null 0.98
X0024:Cyp2c29 UTSW 19 39321599 missense probably benign 0.01
Posted On2014-05-07