Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01984:Sult3a1'

181822

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Sult3a1

Ensembl Gene

ENSMUSG00000069668

Gene Name

sulfotransferase family 3A, member 1

Synonyms

Sultx2

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.172) question?

Stock #

IGL01984

Quality Score

Status

Chromosome

Chromosomal Location

33857721-33879532 bp(+) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

G to T at 33879209 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glycine to Stop codon at position 257 (G257*)

Ref Sequence

ENSEMBL: ENSMUSP00000151228 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092597] [ENSMUST00000218204]

AlphaFold

no structure available at present

Predicted Effect

probably null
Transcript: ENSMUST00000092597
AA Change: G257*

SMART Domains

Protein: ENSMUSP00000090259
Gene: ENSMUSG00000069668
AA Change: G257*

Domain	Start	End	E-Value	Type
Pfam:Sulfotransfer_1	36	283	1.8e-81	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000218204
AA Change: G257*

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 33 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4933434E20Rik	C	T	3: 90,063,230	L24F	probably benign	Het
Adamts16	T	C	13: 70,787,147	D442G	probably damaging	Het
Ankmy1	T	C	1: 92,883,765	T634A	probably damaging	Het
Anxa3	A	T	5: 96,834,771		probably benign	Het
Ccnh	T	C	13: 85,206,151	L202P	probably damaging	Het
Clcn3	A	T	8: 60,929,580	S325T	probably damaging	Het
Clec2d	A	T	6: 129,184,229	E96D	possibly damaging	Het
Csn1s1	A	T	5: 87,676,510		probably benign	Het
Dcun1d5	T	A	9: 7,205,307	Y189N	possibly damaging	Het
Dnah7a	T	C	1: 53,702,015		probably null	Het
Erg	T	G	16: 95,409,927	D15A	probably damaging	Het
Gm11639	T	A	11: 104,738,308	D937E	probably benign	Het
Gm17018	C	T	19: 45,577,030	H148Y	probably benign	Het
Gm21759	T	A	5: 8,180,547		probably benign	Het
Heatr5b	C	T	17: 78,796,497	R1083Q	possibly damaging	Het
Ints3	A	G	3: 90,392,226	S1012P	possibly damaging	Het
Klhl3	C	T	13: 58,011,243		probably benign	Het
Lama4	T	A	10: 39,075,529		probably null	Het
Magi1	A	T	6: 93,708,174	V740D	probably damaging	Het
Nme8	C	A	13: 19,688,980	V165L	probably damaging	Het
Odf2l	G	T	3: 145,139,829	E5*	probably null	Het
Olfr115	T	C	17: 37,623,661		probably benign	Het
Olfr1297	A	G	2: 111,621,582	L164S	probably benign	Het
Olfr683	A	T	7: 105,143,716	D192E	probably benign	Het
Pcnx4	T	C	12: 72,574,409	V1001A	probably benign	Het
Plaa	A	G	4: 94,571,685		probably null	Het
Prkdc	G	A	16: 15,708,779	A1305T	probably benign	Het
Rnps1	T	C	17: 24,424,397		probably benign	Het
St8sia5	T	C	18: 77,248,461	F197L	probably benign	Het
Svep1	A	C	4: 58,068,877	Y2970D	possibly damaging	Het
Tns3	G	T	11: 8,548,992	Y30*	probably null	Het
Ubr1	G	T	2: 120,921,386	P791T	probably damaging	Het
Zfp592	T	C	7: 81,038,644	V1039A	probably benign	Het

Other mutations in Sult3a1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL02269:Sult3a1	APN	10	33879263	missense	probably benign	0.25
IGL02302:Sult3a1	APN	10	33866575	missense	possibly damaging	0.81
IGL02947:Sult3a1	APN	10	33864050	missense	possibly damaging	0.92
IGL02966:Sult3a1	APN	10	33877273	splice site	probably benign
IGL03271:Sult3a1	APN	10	33864001	missense	probably benign
IGL03367:Sult3a1	APN	10	33877346	missense	probably benign	0.01
R0539:Sult3a1	UTSW	10	33866523	missense	probably damaging	1.00
R0627:Sult3a1	UTSW	10	33864014	missense	probably benign	0.00
R0838:Sult3a1	UTSW	10	33879288	missense	probably damaging	0.99
R1538:Sult3a1	UTSW	10	33870170	missense	probably benign	0.29
R1604:Sult3a1	UTSW	10	33866620	missense	probably damaging	1.00
R1622:Sult3a1	UTSW	10	33870250	missense	probably benign	0.39
R3031:Sult3a1	UTSW	10	33877349	missense	possibly damaging	0.70
R4933:Sult3a1	UTSW	10	33866554	missense	probably damaging	1.00
R5943:Sult3a1	UTSW	10	33866641	missense	probably damaging	0.99
R6440:Sult3a1	UTSW	10	33870202	missense	possibly damaging	0.46
R7140:Sult3a1	UTSW	10	33877287	missense	probably damaging	1.00
R7356:Sult3a1	UTSW	10	33866583	missense	probably benign	0.25
R8342:Sult3a1	UTSW	10	33866521	missense	probably damaging	1.00

Posted On

2014-05-07