Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02007:Cyp3a16'

182258

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp3a16

Ensembl Gene

ENSMUSG00000038656

Gene Name

cytochrome P450, family 3, subfamily a, polypeptide 16

Synonyms

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.155) question?

Stock #

IGL02007

Quality Score

Status

Chromosome

Chromosomal Location

145373119-145406533 bp(-) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

T to C at 145378758 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000031633 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000031633]

AlphaFold

Q64481

Predicted Effect

probably benign
Transcript: ENSMUST00000031633

SMART Domains

Protein: ENSMUSP00000031633
Gene: ENSMUSG00000038656

Domain	Start	End	E-Value	Type
low complexity region	3	22	N/A	INTRINSIC
Pfam:p450	38	494	5.5e-132	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 28 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adam28	C	A	14: 68,870,668 (GRCm39)	R335L	possibly damaging	Het
Adgrv1	T	C	13: 81,716,862 (GRCm39)		probably benign	Het
Calcrl	A	G	2: 84,205,668 (GRCm39)	C8R	probably benign	Het
Cntn4	T	A	6: 106,632,490 (GRCm39)	S505T	probably benign	Het
Dync2i2	A	G	2: 29,928,402 (GRCm39)	S75P	probably benign	Het
Fhip1a	G	T	3: 85,629,752 (GRCm39)	P280T	probably damaging	Het
Gpatch11	A	G	17: 79,149,593 (GRCm39)	T198A	probably benign	Het
H2-T15	G	T	17: 36,367,222 (GRCm39)	N333K	possibly damaging	Het
Heatr5a	C	A	12: 51,962,941 (GRCm39)	L986F	probably damaging	Het
Ift172	A	G	5: 31,443,948 (GRCm39)	I90T	probably benign	Het
Igkv3-9	A	G	6: 70,565,445 (GRCm39)		probably benign	Het
Iqsec1	G	A	6: 90,667,331 (GRCm39)	P369S	probably benign	Het
Myh1	C	A	11: 67,111,382 (GRCm39)	T1607K	probably benign	Het
Myo18b	T	C	5: 113,022,838 (GRCm39)		probably benign	Het
Nobox	A	G	6: 43,284,472 (GRCm39)	L58P	probably damaging	Het
Nwd2	T	A	5: 63,962,042 (GRCm39)	I542N	possibly damaging	Het
Or4k51	A	G	2: 111,584,824 (GRCm39)	T77A	probably damaging	Het
Or5p54	A	G	7: 107,553,953 (GRCm39)	Y35C	probably damaging	Het
Osm	C	T	11: 4,189,470 (GRCm39)	R85W	probably damaging	Het
Pcdh20	T	C	14: 88,707,031 (GRCm39)	R90G	probably benign	Het
Pkhd1l1	T	C	15: 44,397,129 (GRCm39)		probably benign	Het
Sec14l2	A	G	11: 4,061,114 (GRCm39)	S116P	probably benign	Het
Selenbp2	A	C	3: 94,605,461 (GRCm39)	N96H	possibly damaging	Het
Smarcal1	T	C	1: 72,635,099 (GRCm39)	S393P	probably damaging	Het
Tbc1d1	A	G	5: 64,414,335 (GRCm39)	Q103R	probably damaging	Het
Tmem63c	T	C	12: 87,119,647 (GRCm39)	Y314H	probably damaging	Het
Zfp663	A	C	2: 165,200,993 (GRCm39)	S14A	probably benign	Het
Zmynd10	A	G	9: 107,427,731 (GRCm39)	N345S	probably damaging	Het

Other mutations in Cyp3a16

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01386:Cyp3a16	APN	5	145,377,244 (GRCm39)	missense	probably damaging	0.98
IGL01964:Cyp3a16	APN	5	145,392,372 (GRCm39)	missense	probably benign	0.41
IGL02139:Cyp3a16	APN	5	145,392,290 (GRCm39)	missense	probably benign	0.10
IGL02177:Cyp3a16	APN	5	145,386,964 (GRCm39)	missense	probably benign	0.43
IGL02407:Cyp3a16	APN	5	145,388,652 (GRCm39)	missense	probably damaging	0.99
IGL02473:Cyp3a16	APN	5	145,377,304 (GRCm39)	missense	possibly damaging	0.54
polywog	UTSW	5	145,404,280 (GRCm39)	nonsense	probably null
R0363:Cyp3a16	UTSW	5	145,392,689 (GRCm39)	splice site	probably benign
R0556:Cyp3a16	UTSW	5	145,392,790 (GRCm39)	missense	probably benign	0.37
R0557:Cyp3a16	UTSW	5	145,406,398 (GRCm39)	missense	unknown
R0636:Cyp3a16	UTSW	5	145,399,895 (GRCm39)	missense	probably benign	0.03
R0749:Cyp3a16	UTSW	5	145,392,987 (GRCm39)	critical splice acceptor site	probably null
R0788:Cyp3a16	UTSW	5	145,401,886 (GRCm39)	missense	probably benign	0.00
R1552:Cyp3a16	UTSW	5	145,373,346 (GRCm39)	missense	probably benign	0.01
R1575:Cyp3a16	UTSW	5	145,373,267 (GRCm39)	missense	probably benign	0.01
R1580:Cyp3a16	UTSW	5	145,378,885 (GRCm39)	missense	probably damaging	1.00
R1580:Cyp3a16	UTSW	5	145,378,884 (GRCm39)	missense	possibly damaging	0.94
R1642:Cyp3a16	UTSW	5	145,406,399 (GRCm39)	missense	unknown
R1763:Cyp3a16	UTSW	5	145,401,841 (GRCm39)	critical splice donor site	probably null
R2029:Cyp3a16	UTSW	5	145,388,667 (GRCm39)	missense	probably damaging	0.96
R2144:Cyp3a16	UTSW	5	145,392,894 (GRCm39)	missense	probably damaging	1.00
R2409:Cyp3a16	UTSW	5	145,377,177 (GRCm39)	missense	probably benign	0.01
R2473:Cyp3a16	UTSW	5	145,392,404 (GRCm39)	missense	possibly damaging	0.79
R2860:Cyp3a16	UTSW	5	145,392,309 (GRCm39)	nonsense	probably null
R2861:Cyp3a16	UTSW	5	145,392,309 (GRCm39)	nonsense	probably null
R3747:Cyp3a16	UTSW	5	145,378,881 (GRCm39)	missense	probably damaging	1.00
R4654:Cyp3a16	UTSW	5	145,373,267 (GRCm39)	missense	probably benign	0.01
R4781:Cyp3a16	UTSW	5	145,392,922 (GRCm39)	missense	possibly damaging	0.85
R4873:Cyp3a16	UTSW	5	145,389,659 (GRCm39)	missense	probably benign	0.01
R4875:Cyp3a16	UTSW	5	145,389,659 (GRCm39)	missense	probably benign	0.01
R4925:Cyp3a16	UTSW	5	145,389,644 (GRCm39)	missense	probably benign	0.00
R5365:Cyp3a16	UTSW	5	145,389,597 (GRCm39)	missense	probably damaging	1.00
R5496:Cyp3a16	UTSW	5	145,404,341 (GRCm39)	missense	probably damaging	1.00
R5640:Cyp3a16	UTSW	5	145,389,633 (GRCm39)	missense	possibly damaging	0.94
R5761:Cyp3a16	UTSW	5	145,378,843 (GRCm39)	missense	possibly damaging	0.79
R6401:Cyp3a16	UTSW	5	145,377,174 (GRCm39)	missense	probably damaging	1.00
R6526:Cyp3a16	UTSW	5	145,392,705 (GRCm39)	missense	probably benign	0.01
R6528:Cyp3a16	UTSW	5	145,377,241 (GRCm39)	missense	probably damaging	1.00
R7000:Cyp3a16	UTSW	5	145,399,980 (GRCm39)	critical splice acceptor site	probably null
R7268:Cyp3a16	UTSW	5	145,404,280 (GRCm39)	nonsense	probably null
R7630:Cyp3a16	UTSW	5	145,373,120 (GRCm39)	splice site	probably null
R7938:Cyp3a16	UTSW	5	145,389,666 (GRCm39)	missense	probably benign	0.00
R8827:Cyp3a16	UTSW	5	145,387,008 (GRCm39)	missense	probably benign	0.38
R9040:Cyp3a16	UTSW	5	145,392,922 (GRCm39)	missense	possibly damaging	0.85
R9137:Cyp3a16	UTSW	5	145,406,413 (GRCm39)	missense	unknown
R9139:Cyp3a16	UTSW	5	145,406,434 (GRCm39)	missense	unknown
R9140:Cyp3a16	UTSW	5	145,406,434 (GRCm39)	missense	unknown
R9284:Cyp3a16	UTSW	5	145,377,304 (GRCm39)	missense	probably damaging	1.00
R9657:Cyp3a16	UTSW	5	145,386,979 (GRCm39)	missense	probably null	1.00
R9680:Cyp3a16	UTSW	5	145,389,690 (GRCm39)	missense	probably damaging	1.00

Posted On

2014-05-07