Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01960:Vmn1r222'

182357

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r222

Ensembl Gene

ENSMUSG00000061022

Gene Name

vomeronasal 1 receptor 222

Synonyms

V1rh16

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.099) question?

Stock #

IGL01960

Quality Score

Status

Chromosome

Chromosomal Location

23416285-23417211 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 23416315 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Lysine to Asparagine at position 299 (K299N)

Ref Sequence

ENSEMBL: ENSMUSP00000076365 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000077116]

AlphaFold

Q8R269

Predicted Effect

probably benign
Transcript: ENSMUST00000077116
AA Change: K299N

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000076365
Gene: ENSMUSG00000061022
AA Change: K299N

Domain	Start	End	E-Value	Type
Pfam:V1R	32	297	3.6e-39	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000225143

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 56 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adgrb2	G	A	4: 129,906,177 (GRCm39)		probably benign	Het
Adh7	T	C	3: 137,932,043 (GRCm39)	I219T	probably damaging	Het
Ankmy1	C	A	1: 92,799,385 (GRCm39)		probably benign	Het
Aoc1	A	G	6: 48,885,537 (GRCm39)	I681V	probably benign	Het
Arfgap3	T	C	15: 83,197,758 (GRCm39)	T333A	probably benign	Het
Cdc42ep4	A	G	11: 113,619,830 (GRCm39)	V187A	probably benign	Het
Cyp4f40	G	A	17: 32,878,535 (GRCm39)	G26R	probably benign	Het
Dnah7b	T	A	1: 46,163,497 (GRCm39)		probably benign	Het
Dnajb4	T	C	3: 151,892,176 (GRCm39)	E219G	probably damaging	Het
Dnmt3b	A	G	2: 153,518,631 (GRCm39)	K578R	possibly damaging	Het
Dst	A	T	1: 34,329,570 (GRCm39)	D4649V	probably damaging	Het
Fam20c	T	C	5: 138,792,075 (GRCm39)	S391P	probably damaging	Het
Fbxw10	A	T	11: 62,767,582 (GRCm39)	Y801F	probably damaging	Het
Frem2	T	G	3: 53,429,725 (GRCm39)	E2775A	probably benign	Het
Frmd4b	A	T	6: 97,272,741 (GRCm39)	S830T	possibly damaging	Het
Gatad2a	T	G	8: 70,362,598 (GRCm39)	S581R	possibly damaging	Het
Gpcpd1	C	T	2: 132,381,818 (GRCm39)		probably null	Het
Igsf10	A	G	3: 59,226,158 (GRCm39)	L2505P	probably benign	Het
Igsf9b	A	G	9: 27,239,902 (GRCm39)	D649G	possibly damaging	Het
Impact	T	C	18: 13,107,815 (GRCm39)	C28R	probably benign	Het
Ino80d	G	T	1: 63,097,306 (GRCm39)	Q863K	probably damaging	Het
Iqsec1	A	C	6: 90,653,762 (GRCm39)	M675R	probably damaging	Het
Kcng3	C	T	17: 83,895,279 (GRCm39)	V396I	probably damaging	Het
Klhl18	A	T	9: 110,279,814 (GRCm39)	D60E	probably benign	Het
Krtap7-1	C	T	16: 89,305,156 (GRCm39)		probably benign	Het
Mal2	T	A	15: 54,461,941 (GRCm39)	Y145*	probably null	Het
Mcpt8	A	T	14: 56,319,864 (GRCm39)		probably null	Het
Mdn1	A	G	4: 32,758,393 (GRCm39)	D4810G	probably benign	Het
Med24	T	C	11: 98,598,368 (GRCm39)	I766V	probably benign	Het
Mga	G	A	2: 119,769,138 (GRCm39)	V1477M	probably damaging	Het
Mybph	T	A	1: 134,121,663 (GRCm39)	V112E	probably benign	Het
Nmur2	A	T	11: 55,931,337 (GRCm39)	S125T	probably damaging	Het
Or2w3	T	C	11: 58,556,691 (GRCm39)	V102A	probably benign	Het
Or6c212	A	G	10: 129,558,756 (GRCm39)	I219T	probably damaging	Het
Or8b44	A	T	9: 38,410,003 (GRCm39)	I13F	probably damaging	Het
Otop3	A	G	11: 115,231,795 (GRCm39)	N220S	probably damaging	Het
Pacsin1	T	G	17: 27,923,809 (GRCm39)		probably null	Het
Pcsk1	A	G	13: 75,241,286 (GRCm39)	R89G	possibly damaging	Het
Pde2a	A	T	7: 101,153,947 (GRCm39)	E509V	probably benign	Het
Pex1	T	C	5: 3,677,588 (GRCm39)		probably benign	Het
Ppp4r4	T	G	12: 103,547,753 (GRCm39)		probably benign	Het
Pygb	T	A	2: 150,655,403 (GRCm39)	N251K	probably benign	Het
Rsf1	C	T	7: 97,310,782 (GRCm39)	T504I	probably benign	Het
Slc5a11	A	T	7: 122,869,163 (GRCm39)	T584S	probably benign	Het
Smad2	G	A	18: 76,395,555 (GRCm39)		probably benign	Het
Srsf6	G	A	2: 162,775,674 (GRCm39)	R161H	probably damaging	Het
Tbx3	T	A	5: 119,820,708 (GRCm39)	S573T	probably benign	Het
Tecpr1	C	T	5: 144,153,737 (GRCm39)	R172Q	probably benign	Het
Ttn	T	A	2: 76,619,244 (GRCm39)		probably null	Het
Ubr2	T	C	17: 47,284,893 (GRCm39)	M542V	probably benign	Het
Unc80	T	C	1: 66,647,659 (GRCm39)		probably benign	Het
Wwp1	A	T	4: 19,662,115 (GRCm39)		probably benign	Het
Zbtb46	T	A	2: 181,065,928 (GRCm39)	H74L	possibly damaging	Het
Zfp106	A	T	2: 120,354,524 (GRCm39)	L1416I	probably damaging	Het
Zfp106	A	G	2: 120,369,803 (GRCm39)	L73S	probably benign	Het
Zfp667	G	A	7: 6,308,336 (GRCm39)	G335R	probably benign	Het

Other mutations in Vmn1r222

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01539:Vmn1r222	APN	13	23,417,059 (GRCm39)	missense	probably benign	0.45
IGL02082:Vmn1r222	APN	13	23,416,499 (GRCm39)	missense	probably damaging	1.00
IGL02616:Vmn1r222	APN	13	23,416,311 (GRCm39)	missense	possibly damaging	0.73
IGL03155:Vmn1r222	APN	13	23,416,863 (GRCm39)	missense	probably damaging	1.00
IGL03333:Vmn1r222	APN	13	23,417,177 (GRCm39)	missense	probably benign	0.18
IGL03391:Vmn1r222	APN	13	23,416,632 (GRCm39)	missense	possibly damaging	0.94
R0137:Vmn1r222	UTSW	13	23,416,974 (GRCm39)	missense	probably damaging	1.00
R1584:Vmn1r222	UTSW	13	23,416,932 (GRCm39)	missense	probably damaging	1.00
R2352:Vmn1r222	UTSW	13	23,416,683 (GRCm39)	missense	probably benign	0.35
R3079:Vmn1r222	UTSW	13	23,416,631 (GRCm39)	missense	possibly damaging	0.75
R3080:Vmn1r222	UTSW	13	23,416,631 (GRCm39)	missense	possibly damaging	0.75
R3963:Vmn1r222	UTSW	13	23,417,102 (GRCm39)	missense	probably benign	0.01
R4448:Vmn1r222	UTSW	13	23,416,830 (GRCm39)	missense	probably damaging	0.99
R4448:Vmn1r222	UTSW	13	23,416,463 (GRCm39)	missense	probably benign	0.11
R4979:Vmn1r222	UTSW	13	23,416,602 (GRCm39)	missense	possibly damaging	0.78
R5054:Vmn1r222	UTSW	13	23,416,901 (GRCm39)	missense	probably damaging	0.98
R5182:Vmn1r222	UTSW	13	23,416,667 (GRCm39)	missense	probably damaging	1.00
R5230:Vmn1r222	UTSW	13	23,417,172 (GRCm39)	missense	probably benign
R5462:Vmn1r222	UTSW	13	23,417,045 (GRCm39)	missense	probably benign	0.05
R5611:Vmn1r222	UTSW	13	23,416,743 (GRCm39)	missense	probably damaging	1.00
R5677:Vmn1r222	UTSW	13	23,416,950 (GRCm39)	missense	probably damaging	1.00
R6298:Vmn1r222	UTSW	13	23,416,965 (GRCm39)	missense	probably benign	0.15
R6655:Vmn1r222	UTSW	13	23,416,886 (GRCm39)	missense	probably damaging	1.00
R6748:Vmn1r222	UTSW	13	23,417,117 (GRCm39)	missense	probably benign	0.00
R6912:Vmn1r222	UTSW	13	23,416,374 (GRCm39)	missense	probably benign	0.44
R7663:Vmn1r222	UTSW	13	23,416,601 (GRCm39)	missense	possibly damaging	0.78
R7764:Vmn1r222	UTSW	13	23,416,529 (GRCm39)	missense	probably damaging	1.00
R8675:Vmn1r222	UTSW	13	23,416,607 (GRCm39)	missense	probably damaging	1.00
R8774:Vmn1r222	UTSW	13	23,416,418 (GRCm39)	missense	probably benign	0.02
R8774-TAIL:Vmn1r222	UTSW	13	23,416,418 (GRCm39)	missense	probably benign	0.02
R9320:Vmn1r222	UTSW	13	23,416,418 (GRCm39)	missense	probably benign	0.02
Z1177:Vmn1r222	UTSW	13	23,416,630 (GRCm39)	missense	possibly damaging	0.94

Posted On

2014-05-07