Incidental Mutation 'IGL01961:Gm9958'
| ID |
182408 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Gm9958
|
| Ensembl Gene |
ENSMUSG00000054945 |
| Gene Name |
predicted gene 9958 |
| Synonyms |
|
| Accession Numbers |
|
| Essential gene? |
Not available
|
| Stock # |
IGL01961
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
5 |
| Chromosomal Location |
90514856-90516347 bp(+) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
C to A
at 90515837 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000151446
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014421]
[ENSMUST00000068250]
[ENSMUST00000081914]
[ENSMUST00000168058]
[ENSMUST00000218526]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000014421
|
| SMART Domains |
Protein: ENSMUSP00000014421
Gene: ENSMUSG00000055204
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
55 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
82 |
130 |
N/A |
INTRINSIC |
|
ANK
|
229 |
258 |
8.62e1 |
SMART |
|
ANK
|
262 |
291 |
3.31e-1 |
SMART |
|
ANK
|
296 |
325 |
3.51e-5 |
SMART |
|
ANK
|
329 |
358 |
1.33e-5 |
SMART |
|
ANK
|
362 |
391 |
3.46e-4 |
SMART |
|
ANK
|
396 |
425 |
3.23e-4 |
SMART |
|
ANK
|
429 |
458 |
1.61e-4 |
SMART |
|
ANK
|
462 |
491 |
1.46e-2 |
SMART |
|
ANK
|
495 |
524 |
3.88e-7 |
SMART |
|
ANK
|
529 |
558 |
4.19e-3 |
SMART |
|
ANK
|
559 |
588 |
1.76e-5 |
SMART |
|
ANK
|
592 |
621 |
3.51e-5 |
SMART |
|
ANK
|
625 |
654 |
5.62e-4 |
SMART |
|
ANK
|
659 |
688 |
1.29e-3 |
SMART |
|
ANK
|
692 |
721 |
1.44e-1 |
SMART |
|
coiled coil region
|
800 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
890 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
968 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
997 |
N/A |
INTRINSIC |
|
low complexity region
|
1046 |
1060 |
N/A |
INTRINSIC |
|
ANK
|
1078 |
1107 |
2.13e-4 |
SMART |
|
ANK
|
1111 |
1140 |
8.19e-6 |
SMART |
|
ANK
|
1145 |
1174 |
1.68e-2 |
SMART |
|
ANK
|
1178 |
1207 |
1.61e-4 |
SMART |
|
ANK
|
1213 |
1242 |
1.43e-5 |
SMART |
|
ANK
|
1247 |
1276 |
1.83e-3 |
SMART |
|
ANK
|
1280 |
1309 |
3.91e-3 |
SMART |
|
ANK
|
1315 |
1344 |
1.93e-2 |
SMART |
|
ANK
|
1348 |
1377 |
8.78e-6 |
SMART |
|
ANK
|
1381 |
1410 |
7.59e-1 |
SMART |
|
coiled coil region
|
1454 |
1522 |
N/A |
INTRINSIC |
|
low complexity region
|
1597 |
1611 |
N/A |
INTRINSIC |
|
low complexity region
|
1616 |
1636 |
N/A |
INTRINSIC |
|
KH
|
1720 |
1790 |
8.31e-14 |
SMART |
|
low complexity region
|
1816 |
1827 |
N/A |
INTRINSIC |
|
low complexity region
|
1834 |
1850 |
N/A |
INTRINSIC |
|
low complexity region
|
1946 |
1989 |
N/A |
INTRINSIC |
|
low complexity region
|
1996 |
2024 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2052 |
N/A |
INTRINSIC |
|
low complexity region
|
2068 |
2077 |
N/A |
INTRINSIC |
|
low complexity region
|
2086 |
2110 |
N/A |
INTRINSIC |
|
low complexity region
|
2175 |
2189 |
N/A |
INTRINSIC |
|
low complexity region
|
2348 |
2365 |
N/A |
INTRINSIC |
|
low complexity region
|
2392 |
2411 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000068250
AA Change: N45K
|
| SMART Domains |
Protein: ENSMUSP00000067622
Gene: ENSMUSG00000054945
AA Change: N45K
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
15 |
33 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000081914
|
| SMART Domains |
Protein: ENSMUSP00000080587
Gene: ENSMUSG00000055204
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
55 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
82 |
130 |
N/A |
INTRINSIC |
|
ANK
|
229 |
258 |
8.62e1 |
SMART |
|
ANK
|
262 |
291 |
3.31e-1 |
SMART |
|
ANK
|
296 |
325 |
3.51e-5 |
SMART |
|
ANK
|
329 |
358 |
1.33e-5 |
SMART |
|
ANK
|
362 |
391 |
3.46e-4 |
SMART |
|
ANK
|
396 |
425 |
3.23e-4 |
SMART |
|
ANK
|
429 |
458 |
1.61e-4 |
SMART |
|
ANK
|
462 |
491 |
1.46e-2 |
SMART |
|
ANK
|
495 |
524 |
3.88e-7 |
SMART |
|
ANK
|
529 |
558 |
4.19e-3 |
SMART |
|
ANK
|
559 |
588 |
1.76e-5 |
SMART |
|
ANK
|
592 |
621 |
3.51e-5 |
SMART |
|
ANK
|
625 |
654 |
5.62e-4 |
SMART |
|
ANK
|
659 |
688 |
1.29e-3 |
SMART |
|
ANK
|
692 |
721 |
1.44e-1 |
SMART |
|
low complexity region
|
795 |
809 |
N/A |
INTRINSIC |
|
ANK
|
827 |
856 |
2.13e-4 |
SMART |
|
ANK
|
860 |
889 |
8.19e-6 |
SMART |
|
ANK
|
894 |
923 |
1.68e-2 |
SMART |
|
ANK
|
927 |
956 |
1.61e-4 |
SMART |
|
ANK
|
962 |
991 |
1.43e-5 |
SMART |
|
ANK
|
996 |
1025 |
1.83e-3 |
SMART |
|
ANK
|
1029 |
1058 |
3.91e-3 |
SMART |
|
ANK
|
1064 |
1093 |
1.93e-2 |
SMART |
|
ANK
|
1097 |
1126 |
8.78e-6 |
SMART |
|
ANK
|
1130 |
1159 |
7.59e-1 |
SMART |
|
coiled coil region
|
1203 |
1271 |
N/A |
INTRINSIC |
|
low complexity region
|
1346 |
1360 |
N/A |
INTRINSIC |
|
low complexity region
|
1365 |
1385 |
N/A |
INTRINSIC |
|
KH
|
1469 |
1539 |
8.31e-14 |
SMART |
|
low complexity region
|
1565 |
1576 |
N/A |
INTRINSIC |
|
low complexity region
|
1583 |
1599 |
N/A |
INTRINSIC |
|
low complexity region
|
1695 |
1738 |
N/A |
INTRINSIC |
|
low complexity region
|
1745 |
1773 |
N/A |
INTRINSIC |
|
low complexity region
|
1784 |
1801 |
N/A |
INTRINSIC |
|
low complexity region
|
1817 |
1826 |
N/A |
INTRINSIC |
|
low complexity region
|
1835 |
1859 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1938 |
N/A |
INTRINSIC |
|
low complexity region
|
2097 |
2114 |
N/A |
INTRINSIC |
|
low complexity region
|
2141 |
2160 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000168058
|
| SMART Domains |
Protein: ENSMUSP00000128960
Gene: ENSMUSG00000055204
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
40 |
N/A |
INTRINSIC |
|
low complexity region
|
55 |
71 |
N/A |
INTRINSIC |
|
low complexity region
|
82 |
130 |
N/A |
INTRINSIC |
|
ANK
|
229 |
258 |
8.62e1 |
SMART |
|
ANK
|
262 |
291 |
3.31e-1 |
SMART |
|
ANK
|
296 |
325 |
3.51e-5 |
SMART |
|
ANK
|
329 |
358 |
1.33e-5 |
SMART |
|
ANK
|
362 |
391 |
3.46e-4 |
SMART |
|
ANK
|
396 |
425 |
3.23e-4 |
SMART |
|
ANK
|
429 |
458 |
1.61e-4 |
SMART |
|
ANK
|
462 |
491 |
1.46e-2 |
SMART |
|
ANK
|
495 |
524 |
3.88e-7 |
SMART |
|
ANK
|
529 |
558 |
4.19e-3 |
SMART |
|
ANK
|
559 |
588 |
1.76e-5 |
SMART |
|
ANK
|
592 |
621 |
3.51e-5 |
SMART |
|
ANK
|
625 |
654 |
5.62e-4 |
SMART |
|
ANK
|
659 |
688 |
1.29e-3 |
SMART |
|
ANK
|
692 |
721 |
1.44e-1 |
SMART |
|
coiled coil region
|
800 |
883 |
N/A |
INTRINSIC |
|
low complexity region
|
890 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
968 |
N/A |
INTRINSIC |
|
low complexity region
|
986 |
997 |
N/A |
INTRINSIC |
|
low complexity region
|
1046 |
1060 |
N/A |
INTRINSIC |
|
ANK
|
1078 |
1107 |
2.13e-4 |
SMART |
|
ANK
|
1111 |
1140 |
8.19e-6 |
SMART |
|
ANK
|
1145 |
1174 |
1.68e-2 |
SMART |
|
ANK
|
1178 |
1207 |
1.61e-4 |
SMART |
|
ANK
|
1213 |
1242 |
1.43e-5 |
SMART |
|
ANK
|
1247 |
1276 |
1.83e-3 |
SMART |
|
ANK
|
1280 |
1309 |
3.91e-3 |
SMART |
|
ANK
|
1315 |
1344 |
1.93e-2 |
SMART |
|
ANK
|
1348 |
1377 |
8.78e-6 |
SMART |
|
ANK
|
1381 |
1410 |
7.59e-1 |
SMART |
|
coiled coil region
|
1454 |
1522 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000202226
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000218526
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 15 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Catsperg2 |
A |
G |
7: 29,421,097 (GRCm39) |
|
probably benign |
Het |
| Kdelr2 |
T |
C |
5: 143,406,556 (GRCm39) |
V202A |
probably benign |
Het |
| Mideas |
T |
C |
12: 84,220,388 (GRCm39) |
K189E |
probably damaging |
Het |
| Mlh3 |
T |
C |
12: 85,313,118 (GRCm39) |
R1023G |
probably benign |
Het |
| Pcdhb7 |
A |
G |
18: 37,475,526 (GRCm39) |
K221E |
probably damaging |
Het |
| Ptprq |
A |
G |
10: 107,479,515 (GRCm39) |
S1171P |
probably damaging |
Het |
| Sez6l |
G |
A |
5: 112,619,597 (GRCm39) |
T345M |
probably damaging |
Het |
| Skint7 |
T |
C |
4: 111,834,660 (GRCm39) |
Y15H |
probably benign |
Het |
| Strip2 |
T |
C |
6: 29,928,426 (GRCm39) |
|
probably benign |
Het |
| Syne1 |
C |
A |
10: 4,993,723 (GRCm39) |
R8339M |
possibly damaging |
Het |
| Tmtc3 |
A |
T |
10: 100,282,893 (GRCm39) |
D887E |
probably benign |
Het |
| Ush1g |
A |
G |
11: 115,209,361 (GRCm39) |
S278P |
probably benign |
Het |
| Wars1 |
A |
T |
12: 108,832,096 (GRCm39) |
M323K |
probably damaging |
Het |
| Zc3h11a |
G |
A |
1: 133,554,805 (GRCm39) |
R392W |
probably benign |
Het |
| Zswim8 |
T |
C |
14: 20,762,402 (GRCm39) |
F305L |
possibly damaging |
Het |
|
| Other mutations in Gm9958 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
R7970:Gm9958
|
UTSW |
5 |
90,515,568 (GRCm39) |
unclassified |
probably benign |
|
|
Z1177:Gm9958
|
UTSW |
5 |
90,515,857 (GRCm39) |
missense |
unknown |
|
|
| Posted On |
2014-05-07 |
Incidental Mutation