Incidental Mutation 'IGL01976:Gm13103'
ID182678
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm13103
Ensembl Gene ENSMUSG00000029451
Gene Namepredicted gene 13103
Synonyms
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.075) question?
Stock #IGL01976
Quality Score
Status
Chromosome4
Chromosomal Location143846497-143853637 bp(+) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) A to G at 143852793 bp
ZygosityHeterozygous
Amino Acid Change Asparagine to Serine at position 316 (N316S)
Ref Sequence ENSEMBL: ENSMUSP00000092099 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000094522] [ENSMUST00000105768] [ENSMUST00000139747]
Predicted Effect probably benign
Transcript: ENSMUST00000094522
AA Change: N316S

PolyPhen 2 Score 0.175 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000092099
Gene: ENSMUSG00000029451
AA Change: N316S

DomainStartEndE-ValueType
low complexity region 403 413 N/A INTRINSIC
Predicted Effect silent
Transcript: ENSMUST00000105768
Predicted Effect probably benign
Transcript: ENSMUST00000139747
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 31 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Alms1 T C 6: 85,622,665 V1960A possibly damaging Het
Asph A T 4: 9,475,471 N537K probably damaging Het
Bnip2 T C 9: 70,000,834 probably benign Het
Cc2d2a C A 5: 43,683,115 Q104K probably benign Het
Cd300ld A G 11: 114,987,444 S81P probably damaging Het
Clec4a1 T C 6: 122,928,074 probably benign Het
Dnajb8 T C 6: 88,222,526 S15P probably damaging Het
Erp27 C A 6: 136,919,989 V72L probably damaging Het
Gpr156 A G 16: 37,979,033 T131A probably damaging Het
Grk1 T C 8: 13,415,993 V479A probably damaging Het
Hist1h2ba T A 13: 23,933,999 D53V possibly damaging Het
Hspg2 A G 4: 137,561,926 D3784G probably damaging Het
Irf2 A T 8: 46,807,225 K26M probably damaging Het
Irx6 C A 8: 92,676,089 C27* probably null Het
Izumo1r C T 9: 14,901,679 C99Y probably damaging Het
Klrb1a T A 6: 128,618,109 T132S probably benign Het
Mmp13 C T 9: 7,278,974 probably benign Het
Myo5b G A 18: 74,698,277 R766Q probably damaging Het
Myt1 T C 2: 181,795,739 L81P probably damaging Het
Nfat5 G A 8: 107,367,559 V793I probably damaging Het
Nup210 A G 6: 91,053,614 V108A possibly damaging Het
Olfr32 A G 2: 90,138,924 S72P probably damaging Het
Omd T A 13: 49,589,643 Y56* probably null Het
Psmd9 A G 5: 123,234,634 E60G probably damaging Het
Rab11fip1 T C 8: 27,152,797 E658G possibly damaging Het
Smchd1 T A 17: 71,394,725 K1091* probably null Het
Supt16 A T 14: 52,182,307 N111K possibly damaging Het
Trrap A G 5: 144,856,989 T3666A probably benign Het
Ttn T C 2: 76,785,751 D8289G probably damaging Het
Ush2a T A 1: 188,911,241 S4267T probably benign Het
Usp50 T A 2: 126,709,466 E31V probably benign Het
Other mutations in Gm13103
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01363:Gm13103 APN 4 143853276 missense probably benign 0.01
IGL01383:Gm13103 APN 4 143846532 utr 5 prime probably benign
IGL01735:Gm13103 APN 4 143851831 missense probably damaging 1.00
IGL03096:Gm13103 APN 4 143850915 missense probably benign 0.01
IGL03280:Gm13103 APN 4 143851919 missense possibly damaging 0.74
IGL03295:Gm13103 APN 4 143853189 missense probably damaging 1.00
FR4342:Gm13103 UTSW 4 143851643 frame shift probably null
PIT4687001:Gm13103 UTSW 4 143846533 start gained probably benign
R0218:Gm13103 UTSW 4 143851831 missense probably damaging 1.00
R0612:Gm13103 UTSW 4 143852088 unclassified probably benign
R1755:Gm13103 UTSW 4 143850810 missense probably damaging 1.00
R2509:Gm13103 UTSW 4 143851991 missense probably benign 0.01
R2510:Gm13103 UTSW 4 143851991 missense probably benign 0.01
R2511:Gm13103 UTSW 4 143851991 missense probably benign 0.01
R4603:Gm13103 UTSW 4 143852881 missense probably benign 0.01
R4694:Gm13103 UTSW 4 143852960 missense probably damaging 0.97
R4856:Gm13103 UTSW 4 143853303 missense probably benign 0.00
R4886:Gm13103 UTSW 4 143853303 missense probably benign 0.00
R4927:Gm13103 UTSW 4 143851617 missense probably damaging 1.00
R5168:Gm13103 UTSW 4 143853198 missense probably benign 0.02
R5270:Gm13103 UTSW 4 143851898 missense probably damaging 0.97
R5402:Gm13103 UTSW 4 143851655 critical splice donor site probably null
R5618:Gm13103 UTSW 4 143850693 missense possibly damaging 0.92
R6078:Gm13103 UTSW 4 143851585 missense possibly damaging 0.58
R6138:Gm13103 UTSW 4 143851585 missense possibly damaging 0.58
R6362:Gm13103 UTSW 4 143852865 missense probably damaging 0.99
R6526:Gm13103 UTSW 4 143852814 missense probably damaging 1.00
R6555:Gm13103 UTSW 4 143851570 missense possibly damaging 0.58
R6595:Gm13103 UTSW 4 143852756 missense probably damaging 1.00
R6675:Gm13103 UTSW 4 143853258 missense probably damaging 0.98
R7216:Gm13103 UTSW 4 143851829 missense probably damaging 0.96
R7282:Gm13103 UTSW 4 143851881 missense possibly damaging 0.85
R7424:Gm13103 UTSW 4 143853209 missense probably benign 0.01
R7511:Gm13103 UTSW 4 143846546 missense possibly damaging 0.68
R7591:Gm13103 UTSW 4 143850911 missense probably benign 0.01
R7868:Gm13103 UTSW 4 143851584 missense possibly damaging 0.58
R8192:Gm13103 UTSW 4 143851539 nonsense probably null
R8244:Gm13103 UTSW 4 143853284 missense probably damaging 1.00
R8256:Gm13103 UTSW 4 143851685 missense probably benign 0.05
U15987:Gm13103 UTSW 4 143851585 missense possibly damaging 0.58
Z1176:Gm13103 UTSW 4 143853110 missense probably benign 0.22
Posted On2014-05-07