Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL01980:Vmn1r23'

182691

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn1r23

Ensembl Gene

ENSMUSG00000093376

Gene Name

vomeronasal 1 receptor 23

Synonyms

V1rc24

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.157) question?

Stock #

IGL01980

Quality Score

Status

Chromosome

Chromosomal Location

57925842-57926838 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 57926490 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Glutamine to Leucine at position 101 (Q101L)

Ref Sequence

ENSEMBL: ENSMUSP00000135676 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000175817]

AlphaFold

Q8R2D0

Predicted Effect

probably damaging
Transcript: ENSMUST00000175817
AA Change: Q101L

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

SMART Domains

Protein: ENSMUSP00000135676
Gene: ENSMUSG00000093376
AA Change: Q101L

Domain	Start	End	E-Value	Type
Pfam:V1R	28	293	3.1e-57	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 38 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Ankrd60	C	T	2: 173,571,203	C164Y	probably benign	Het
Atp13a2	C	T	4: 141,006,152	A979V	probably benign	Het
Col5a2	C	T	1: 45,382,233		probably benign	Het
Col6a6	T	C	9: 105,780,985	N676S	probably damaging	Het
Cpa1	T	C	6: 30,641,582	F192L	possibly damaging	Het
Entpd6	T	A	2: 150,762,366		probably null	Het
Fam185a	A	G	5: 21,459,173	K302E	probably damaging	Het
Il12rb2	T	C	6: 67,360,535	K121E	probably benign	Het
Impg2	G	A	16: 56,221,527	C178Y	probably damaging	Het
Kdm3b	G	T	18: 34,834,236	C1698F	probably damaging	Het
Llgl2	A	G	11: 115,850,025	D451G	probably damaging	Het
Mgat4b	T	A	11: 50,230,713	L52Q	probably damaging	Het
Mmp9	C	A	2: 164,950,916	S363R	probably benign	Het
Mtfmt	A	G	9: 65,437,074	Y94C	probably benign	Het
Myo7b	G	A	18: 31,961,900	L1881F	possibly damaging	Het
Olfr642	A	T	7: 104,050,093	M87K	probably benign	Het
Olfr782	G	T	10: 129,351,517		probably benign	Het
Pex5	T	C	6: 124,398,380	N524S	probably damaging	Het
Plppr1	A	T	4: 49,319,992	Y206F	possibly damaging	Het
Polr3e	A	G	7: 120,940,296		probably benign	Het
Rhbdd1	A	G	1: 82,340,834		probably benign	Het
Rims4	A	T	2: 163,865,782		probably benign	Het
Smarcal1	A	T	1: 72,616,520	K653*	probably null	Het
Stt3b	C	T	9: 115,276,699		probably null	Het
Syt8	C	A	7: 142,440,140	L343M	probably damaging	Het
Tbc1d23	G	A	16: 57,189,252		probably benign	Het
Tfec	T	C	6: 16,845,466	I65V	probably damaging	Het
Tmem236	A	T	2: 14,218,905	Q168H	probably benign	Het
Tmem25	G	A	9: 44,798,271	R78*	probably null	Het
Tnip2	A	G	5: 34,496,868	V288A	probably benign	Het
Ttc1	G	A	11: 43,730,464		probably benign	Het
Tubb4b-ps1	A	C	5: 7,179,843		probably benign	Het
Tut1	T	C	19: 8,954,000	C21R	probably damaging	Het
Ubr4	C	A	4: 139,429,602	Q2313K	probably damaging	Het
Unc5b	T	C	10: 60,780,187	E119G	probably damaging	Het
Vmn2r77	A	G	7: 86,801,470	D188G	probably benign	Het
Vmn2r79	A	G	7: 87,037,082	E557G	possibly damaging	Het
Zfp738	A	G	13: 67,669,977	F632L	possibly damaging	Het

Other mutations in Vmn1r23

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01563:Vmn1r23	APN	6	57926076	missense	possibly damaging	0.89
IGL02934:Vmn1r23	APN	6	57925929	missense	probably benign	0.26
IGL03153:Vmn1r23	APN	6	57925932	missense	probably damaging	0.98
R0410:Vmn1r23	UTSW	6	57926190	missense	probably benign	0.11
R0452:Vmn1r23	UTSW	6	57926484	missense	possibly damaging	0.90
R0590:Vmn1r23	UTSW	6	57926364	missense	probably benign	0.43
R0647:Vmn1r23	UTSW	6	57926184	missense	probably benign
R0692:Vmn1r23	UTSW	6	57926125	nonsense	probably null
R1674:Vmn1r23	UTSW	6	57926061	missense	possibly damaging	0.75
R1744:Vmn1r23	UTSW	6	57925925	missense	possibly damaging	0.81
R1774:Vmn1r23	UTSW	6	57926690	missense	probably damaging	0.97
R2101:Vmn1r23	UTSW	6	57926452	missense	possibly damaging	0.90
R2202:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R2204:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R2205:Vmn1r23	UTSW	6	57926619	missense	probably benign	0.01
R4282:Vmn1r23	UTSW	6	57926467	missense	probably benign	0.27
R4408:Vmn1r23	UTSW	6	57926368	missense	probably benign	0.01
R4532:Vmn1r23	UTSW	6	57925929	missense	probably benign	0.21
R4690:Vmn1r23	UTSW	6	57926025	missense	probably benign
R4700:Vmn1r23	UTSW	6	57926205	missense	probably benign	0.17
R4894:Vmn1r23	UTSW	6	57926325	missense	probably benign	0.00
R6164:Vmn1r23	UTSW	6	57926055	missense	possibly damaging	0.90
R6930:Vmn1r23	UTSW	6	57926145	missense	probably benign
R7129:Vmn1r23	UTSW	6	57926076	missense	possibly damaging	0.89
R7731:Vmn1r23	UTSW	6	57926334	missense	probably benign	0.03
R7877:Vmn1r23	UTSW	6	57926556	missense	probably benign
R8751:Vmn1r23	UTSW	6	57926467	missense	probably benign	0.27
R8809:Vmn1r23	UTSW	6	57926367	missense	probably damaging	0.97

Posted On

2014-05-07