Incidental Mutation 'IGL02000:Gm10406'
ID182989
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm10406
Ensembl Gene ENSMUSG00000093985
Gene Namepredicted gene 10406
Synonyms
Accession Numbers
Is this an essential gene? Not available question?
Stock #IGL02000
Quality Score
Status
Chromosome14
Chromosomal Location7006115-7027449 bp(-) (GRCm38)
Type of Mutationmissense
DNA Base Change (assembly) C to T at 7009867 bp
ZygosityHeterozygous
Amino Acid Change Glycine to Glutamic Acid at position 181 (G181E)
Ref Sequence ENSEMBL: ENSMUSP00000130661 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000100895] [ENSMUST00000170738]
Predicted Effect probably benign
Transcript: ENSMUST00000100895
AA Change: G181E

PolyPhen 2 Score 0.084 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000098455
Gene: ENSMUSG00000093985
AA Change: G181E

DomainStartEndE-ValueType
Pfam:Takusan 46 129 1.8e-32 PFAM
Predicted Effect probably benign
Transcript: ENSMUST00000170738
AA Change: G181E

PolyPhen 2 Score 0.084 (Sensitivity: 0.93; Specificity: 0.85)
SMART Domains Protein: ENSMUSP00000130661
Gene: ENSMUSG00000093985
AA Change: G181E

DomainStartEndE-ValueType
Pfam:Takusan 48 128 3.9e-23 PFAM
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arid5a T C 1: 36,319,497 F450S probably damaging Het
Astn1 C T 1: 158,674,614 R1133C probably damaging Het
Cd101 G A 3: 101,012,082 P568L probably benign Het
Cdkl4 T C 17: 80,543,763 E170G probably damaging Het
Chit1 A G 1: 134,146,675 E240G probably benign Het
Duox2 T C 2: 122,290,709 T741A probably benign Het
Eef2 T C 10: 81,180,011 V427A probably benign Het
Ewsr1 T C 11: 5,088,077 D105G probably damaging Het
Ftsj3 C T 11: 106,250,407 R629Q probably benign Het
Ilk A G 7: 105,741,169 H185R probably benign Het
Lamc1 A T 1: 153,240,433 C1001S probably damaging Het
Mcidas T C 13: 112,997,440 S153P probably benign Het
Mtcl1 T C 17: 66,354,190 E931G probably benign Het
Myo10 C T 15: 25,808,066 R1925C probably damaging Het
Notch3 A G 17: 32,122,742 V2012A probably damaging Het
Olfr809 C A 10: 129,776,069 H67N probably benign Het
Parp6 A G 9: 59,648,892 M542V probably benign Het
Rab27a G A 9: 73,084,972 G94D probably damaging Het
Ralgapb A G 2: 158,454,114 probably benign Het
Rassf4 T C 6: 116,645,972 E26G probably benign Het
Rnf166 C T 8: 122,467,222 D221N probably damaging Het
Rptn G T 3: 93,396,428 G356V probably benign Het
Rwdd2b T A 16: 87,436,940 probably benign Het
Scfd1 T A 12: 51,414,117 S337T probably benign Het
Sel1l3 T A 5: 53,145,493 D678V probably damaging Het
Sidt1 A T 16: 44,286,369 F233I probably damaging Het
Slc12a4 T C 8: 105,945,232 D917G probably damaging Het
Slc22a2 A T 17: 12,584,383 I35F possibly damaging Het
Smco1 A T 16: 32,273,933 T141S possibly damaging Het
Svs6 T C 2: 164,317,432 probably benign Het
Syne2 C T 12: 76,015,645 A4247V probably damaging Het
Tacc2 T A 7: 130,729,168 probably null Het
Tgm4 A T 9: 123,056,466 I358F probably damaging Het
Thnsl2 A G 6: 71,134,219 S222P probably damaging Het
Tmem25 G A 9: 44,798,271 R78* probably null Het
Ube2l6 T C 2: 84,809,162 probably benign Het
Usp10 T A 8: 119,948,741 Y63N possibly damaging Het
Vit A G 17: 78,605,486 I283V possibly damaging Het
Vmn1r214 G A 13: 23,035,100 V255I possibly damaging Het
Xpo1 A G 11: 23,296,003 R1038G probably damaging Het
Ybx1 T A 4: 119,282,312 N50I probably damaging Het
Zhx1 T C 15: 58,054,287 K188E probably damaging Het
Other mutations in Gm10406
AlleleSourceChrCoordTypePredicted EffectPPH Score
R7181:Gm10406 UTSW 14 7027359 splice site probably null
Posted On2014-05-07