Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02052:Ceacam11'

185101

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Ceacam11

Ensembl Gene

ENSMUSG00000030368

Gene Name

CEA cell adhesion molecule 11

Synonyms

Ceacam11-C1, Ceacam11-C3, Ceacam11-C4, 1600015D01Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.050) question?

Stock #

IGL02052

Quality Score

Status

Chromosome

Chromosomal Location

17706092-17712481 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 17707548 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Glycine at position 111 (S111G)

Ref Sequence

ENSEMBL: ENSMUSP00000092393 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094799]

AlphaFold

Q9D0Z8

Predicted Effect

probably benign
Transcript: ENSMUST00000094799
AA Change: S111G

PolyPhen 2 Score 0.094 (Sensitivity: 0.93; Specificity: 0.85)

SMART Domains

Protein: ENSMUSP00000092393
Gene: ENSMUSG00000030368
AA Change: S111G

Domain	Start	End	E-Value	Type
IG_like	40	141	8.06e0	SMART
IG_like	160	261	8.5e0	SMART

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arhgef37	C	T	18: 61,632,839 (GRCm39)	V533M	probably damaging	Het
Bicd2	A	G	13: 49,532,665 (GRCm39)	D343G	possibly damaging	Het
Ccl26	C	T	5: 135,592,193 (GRCm39)	S48N	possibly damaging	Het
Cdkn1b	A	T	6: 134,897,970 (GRCm39)	R30*	probably null	Het
Cds1	G	T	5: 101,962,338 (GRCm39)	V318L	probably benign	Het
Cntn1	A	C	15: 92,189,584 (GRCm39)	I636L	possibly damaging	Het
Cog2	G	A	8: 125,269,627 (GRCm39)		probably null	Het
Cyp2g1	G	A	7: 26,513,719 (GRCm39)		probably benign	Het
Ddx54	T	C	5: 120,763,783 (GRCm39)	V644A	possibly damaging	Het
Dnah1	T	C	14: 30,990,743 (GRCm39)	Q3192R	probably damaging	Het
Dyrk2	T	G	10: 118,696,448 (GRCm39)	H270P	probably damaging	Het
Ephb6	A	G	6: 41,590,256 (GRCm39)	T3A	probably benign	Het
Fam120a	G	A	13: 49,087,421 (GRCm39)		probably benign	Het
Fam184a	A	G	10: 53,573,216 (GRCm39)		probably benign	Het
Fmo1	A	G	1: 162,677,629 (GRCm39)		probably null	Het
Gaa	A	G	11: 119,175,021 (GRCm39)	Y874C	possibly damaging	Het
Gabrr1	T	A	4: 33,152,567 (GRCm39)	I169N	probably damaging	Het
Gm13734	T	C	2: 86,966,665 (GRCm39)		probably null	Het
Gnb1	T	C	4: 155,618,148 (GRCm39)		probably benign	Het
Hecw2	G	T	1: 53,965,670 (GRCm39)	F385L	probably benign	Het
Kif5a	C	T	10: 127,079,368 (GRCm39)	V277M	probably damaging	Het
Mogat2	A	T	7: 98,887,771 (GRCm39)	M1K	probably null	Het
Mrgprx2	A	T	7: 48,132,042 (GRCm39)	W259R	possibly damaging	Het
Nf1	T	C	11: 79,303,553 (GRCm39)	L410S	probably damaging	Het
Ntn4	T	G	10: 93,543,211 (GRCm39)	N312K	probably damaging	Het
Papss2	T	C	19: 32,637,983 (GRCm39)	V365A	possibly damaging	Het
Pde4c	A	G	8: 71,201,062 (GRCm39)	N420S	probably damaging	Het
Plec	C	T	15: 76,064,541 (GRCm39)	R1911H	probably damaging	Het
Pramel21	A	C	4: 143,341,643 (GRCm39)	D24A	probably benign	Het
Rnf19b	A	G	4: 128,965,613 (GRCm39)	H237R	probably damaging	Het
Slfn4	T	C	11: 83,077,800 (GRCm39)	L196P	possibly damaging	Het
Steap2	G	T	5: 5,723,586 (GRCm39)	F431L	probably damaging	Het
Tex15	A	G	8: 34,072,493 (GRCm39)	E2680G	probably benign	Het
Tmprss15	A	T	16: 78,884,394 (GRCm39)	I96N	probably damaging	Het
Trim34a	T	G	7: 103,897,038 (GRCm39)	V34G	probably benign	Het
Ttyh1	A	G	7: 4,133,573 (GRCm39)		probably benign	Het
Usp29	A	C	7: 6,965,525 (GRCm39)	H456P	probably benign	Het
Wdfy1	A	G	1: 79,692,661 (GRCm39)	S219P	probably damaging	Het
Zfp738	A	T	13: 67,819,600 (GRCm39)	S117R	possibly damaging	Het

Other mutations in Ceacam11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00844:Ceacam11	APN	7	17,707,595 (GRCm39)	missense	possibly damaging	0.82
IGL01161:Ceacam11	APN	7	17,712,435 (GRCm39)	missense	possibly damaging	0.95
IGL01744:Ceacam11	APN	7	17,707,323 (GRCm39)	missense	possibly damaging	0.95
IGL02337:Ceacam11	APN	7	17,707,550 (GRCm39)	missense	probably benign	0.09
IGL03079:Ceacam11	APN	7	17,712,361 (GRCm39)	missense	probably benign	0.02
R1902:Ceacam11	UTSW	7	17,709,252 (GRCm39)	missense	probably benign	0.05
R2204:Ceacam11	UTSW	7	17,709,273 (GRCm39)	missense	possibly damaging	0.92
R2851:Ceacam11	UTSW	7	17,712,451 (GRCm39)	missense	probably benign	0.01
R3237:Ceacam11	UTSW	7	17,707,379 (GRCm39)	missense	probably benign	0.02
R4786:Ceacam11	UTSW	7	17,706,239 (GRCm39)	critical splice donor site	probably null
R8097:Ceacam11	UTSW	7	17,709,455 (GRCm39)	nonsense	probably null
R8109:Ceacam11	UTSW	7	17,709,243 (GRCm39)	missense	probably benign	0.01
R8476:Ceacam11	UTSW	7	17,707,618 (GRCm39)	missense	probably benign	0.03
R8878:Ceacam11	UTSW	7	17,709,536 (GRCm39)	missense	probably benign	0.01
R9492:Ceacam11	UTSW	7	17,709,468 (GRCm39)	missense	probably benign	0.00

Posted On

2014-05-07