Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02052:Cyp2g1'

185119

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Cyp2g1

Ensembl Gene

ENSMUSG00000049685

Gene Name

cytochrome P450, family 2, subfamily g, polypeptide 1

Synonyms

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02052

Quality Score

Status

Chromosome

Chromosomal Location

26808892-26821205 bp(+) (GRCm38)

Type of Mutation

splice site

DNA Base Change (assembly)

G to A at 26814294 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000047150 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000040944]

AlphaFold

Q9WV19

Predicted Effect

probably benign
Transcript: ENSMUST00000040944

SMART Domains

Protein: ENSMUSP00000047150
Gene: ENSMUSG00000049685

Domain	Start	End	E-Value	Type
low complexity region	12	23	N/A	INTRINSIC
Pfam:p450	34	491	4e-150	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000205273

Coding Region Coverage

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 39 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arhgef37	C	T	18: 61,499,768	V533M	probably damaging	Het
Bicd2	A	G	13: 49,379,189	D343G	possibly damaging	Het
Ccl26	C	T	5: 135,563,339	S48N	possibly damaging	Het
Cdkn1b	A	T	6: 134,921,007	R30*	probably null	Het
Cds1	G	T	5: 101,814,472	V318L	probably benign	Het
Ceacam11	A	G	7: 17,973,623	S111G	probably benign	Het
Cntn1	A	C	15: 92,291,703	I636L	possibly damaging	Het
Cog2	G	A	8: 124,542,888		probably null	Het
Ddx54	T	C	5: 120,625,718	V644A	possibly damaging	Het
Dnah1	T	C	14: 31,268,786	Q3192R	probably damaging	Het
Dyrk2	T	G	10: 118,860,543	H270P	probably damaging	Het
Ephb6	A	G	6: 41,613,322	T3A	probably benign	Het
Fam120a	G	A	13: 48,933,945		probably benign	Het
Fam184a	A	G	10: 53,697,120		probably benign	Het
Fmo1	A	G	1: 162,850,060		probably null	Het
Gaa	A	G	11: 119,284,195	Y874C	possibly damaging	Het
Gabrr1	T	A	4: 33,152,567	I169N	probably damaging	Het
Gm13083	A	C	4: 143,615,073	D24A	probably benign	Het
Gm13734	T	C	2: 87,136,321		probably null	Het
Gnb1	T	C	4: 155,533,691		probably benign	Het
Hecw2	G	T	1: 53,926,511	F385L	probably benign	Het
Kif5a	C	T	10: 127,243,499	V277M	probably damaging	Het
Mogat2	A	T	7: 99,238,564	M1K	probably null	Het
Mrgprx2	A	T	7: 48,482,294	W259R	possibly damaging	Het
Nf1	T	C	11: 79,412,727	L410S	probably damaging	Het
Ntn4	T	G	10: 93,707,349	N312K	probably damaging	Het
Papss2	T	C	19: 32,660,583	V365A	possibly damaging	Het
Pde4c	A	G	8: 70,748,413	N420S	probably damaging	Het
Plec	C	T	15: 76,180,341	R1911H	probably damaging	Het
Rnf19b	A	G	4: 129,071,820	H237R	probably damaging	Het
Slfn4	T	C	11: 83,186,974	L196P	possibly damaging	Het
Steap2	G	T	5: 5,673,586	F431L	probably damaging	Het
Tex15	A	G	8: 33,582,465	E2680G	probably benign	Het
Tmprss15	A	T	16: 79,087,506	I96N	probably damaging	Het
Trim34a	T	G	7: 104,247,831	V34G	probably benign	Het
Ttyh1	A	G	7: 4,130,574		probably benign	Het
Usp29	A	C	7: 6,962,526	H456P	probably benign	Het
Wdfy1	A	G	1: 79,714,944	S219P	probably damaging	Het
Zfp738	A	T	13: 67,671,481	S117R	possibly damaging	Het

Other mutations in Cyp2g1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01134:Cyp2g1	APN	7	26809831	missense	probably benign	0.05
IGL01137:Cyp2g1	APN	7	26814259	missense	possibly damaging	0.87
IGL02338:Cyp2g1	APN	7	26814804	splice site	probably benign
IGL02452:Cyp2g1	APN	7	26811446	missense	probably benign	0.28
IGL02523:Cyp2g1	APN	7	26819187	missense	probably damaging	1.00
IGL03165:Cyp2g1	APN	7	26809776	missense	possibly damaging	0.94
IGL03230:Cyp2g1	APN	7	26819403	missense	probably damaging	1.00
PIT4472001:Cyp2g1	UTSW	7	26814194	missense	probably benign	0.28
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0106:Cyp2g1	UTSW	7	26814182	missense	probably damaging	1.00
R0380:Cyp2g1	UTSW	7	26814295	splice site	probably benign
R0697:Cyp2g1	UTSW	7	26814727	nonsense	probably null
R0830:Cyp2g1	UTSW	7	26814791	missense	probably benign	0.00
R1660:Cyp2g1	UTSW	7	26809682	critical splice acceptor site	probably null
R2093:Cyp2g1	UTSW	7	26819433	missense	probably benign	0.35
R2131:Cyp2g1	UTSW	7	26820710	missense	probably damaging	0.99
R4606:Cyp2g1	UTSW	7	26814154	missense	possibly damaging	0.80
R5030:Cyp2g1	UTSW	7	26820801	missense	probably benign	0.06
R5574:Cyp2g1	UTSW	7	26820740	missense	possibly damaging	0.81
R5877:Cyp2g1	UTSW	7	26816640	missense	possibly damaging	0.80
R6745:Cyp2g1	UTSW	7	26814179	missense	probably damaging	1.00
R7040:Cyp2g1	UTSW	7	26820759	missense	probably damaging	0.99
R7223:Cyp2g1	UTSW	7	26814632	missense	probably damaging	0.98
R7934:Cyp2g1	UTSW	7	26819193	missense	probably damaging	1.00
R8112:Cyp2g1	UTSW	7	26819461	missense	probably benign
R8177:Cyp2g1	UTSW	7	26819153	missense	probably damaging	1.00
R8194:Cyp2g1	UTSW	7	26814734	missense	possibly damaging	0.89
R9043:Cyp2g1	UTSW	7	26809831	missense	probably benign	0.05
R9406:Cyp2g1	UTSW	7	26819485	critical splice donor site	probably null
R9441:Cyp2g1	UTSW	7	26814635	missense	possibly damaging	0.72
X0067:Cyp2g1	UTSW	7	26820762	missense	possibly damaging	0.70

Posted On

2014-05-07