Incidental Mutation 'IGL02055:Vmn1r42'
| ID |
185216 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Vmn1r42
|
| Ensembl Gene |
ENSMUSG00000068232 |
| Gene Name |
vomeronasal 1 receptor 42 |
| Synonyms |
V1ra6 |
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.059)
|
| Stock # |
IGL02055
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
6 |
| Chromosomal Location |
89821500-89822597 bp(-) (GRCm39) |
| Type of Mutation |
utr 5 prime |
| DNA Base Change (assembly) |
T to C
at 89822571 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000154442
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089419]
[ENSMUST00000226436]
[ENSMUST00000227279]
|
| AlphaFold |
Q8VBS7 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000089419
|
| SMART Domains |
Protein: ENSMUSP00000086840
Gene: ENSMUSG00000068232
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:V1R
|
54 |
318 |
3.6e-132 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000226436
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000227279
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 34 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Ap1b1 |
T |
A |
11: 4,974,452 (GRCm39) |
C353* |
probably null |
Het |
| Asl |
C |
T |
5: 130,041,891 (GRCm39) |
G309R |
possibly damaging |
Het |
| B4galnt4 |
T |
C |
7: 140,650,731 (GRCm39) |
F835S |
probably damaging |
Het |
| Bltp2 |
A |
G |
11: 78,177,457 (GRCm39) |
T1921A |
probably damaging |
Het |
| Carmil2 |
A |
G |
8: 106,423,539 (GRCm39) |
|
probably benign |
Het |
| Ccnt2 |
C |
A |
1: 127,719,447 (GRCm39) |
P116T |
possibly damaging |
Het |
| Clcn1 |
T |
G |
6: 42,284,489 (GRCm39) |
M609R |
probably damaging |
Het |
| Csmd1 |
A |
G |
8: 16,119,015 (GRCm39) |
I1858T |
probably damaging |
Het |
| Eefsec |
T |
C |
6: 88,353,385 (GRCm39) |
I95V |
probably damaging |
Het |
| Galk2 |
A |
G |
2: 125,773,324 (GRCm39) |
K252R |
probably benign |
Het |
| Gbp2 |
A |
T |
3: 142,337,991 (GRCm39) |
N369I |
probably benign |
Het |
| Glis2 |
G |
T |
16: 4,431,972 (GRCm39) |
|
probably benign |
Het |
| Igdcc3 |
T |
C |
9: 65,088,562 (GRCm39) |
V388A |
possibly damaging |
Het |
| Klhl1 |
A |
G |
14: 96,517,539 (GRCm39) |
F379S |
possibly damaging |
Het |
| Or5b12 |
T |
A |
19: 12,896,930 (GRCm39) |
I248F |
possibly damaging |
Het |
| Pigm |
C |
T |
1: 172,204,732 (GRCm39) |
S156L |
probably benign |
Het |
| Pikfyve |
T |
C |
1: 65,277,703 (GRCm39) |
|
probably null |
Het |
| Ppp6r3 |
A |
G |
19: 3,571,781 (GRCm39) |
F123L |
probably benign |
Het |
| Pum1 |
C |
A |
4: 130,481,365 (GRCm39) |
S637R |
probably benign |
Het |
| Rp1 |
A |
G |
1: 4,422,745 (GRCm39) |
S112P |
probably damaging |
Het |
| Serpina3k |
A |
T |
12: 104,307,295 (GRCm39) |
K176* |
probably null |
Het |
| Smad4 |
A |
G |
18: 73,774,999 (GRCm39) |
|
probably benign |
Het |
| Tas2r140 |
T |
A |
6: 40,468,493 (GRCm39) |
F108I |
probably damaging |
Het |
| Tbc1d20 |
G |
A |
2: 152,149,978 (GRCm39) |
R73H |
probably damaging |
Het |
| Tmem131l |
T |
C |
3: 83,817,673 (GRCm39) |
|
probably null |
Het |
| Tmem86b |
A |
C |
7: 4,631,762 (GRCm39) |
|
probably benign |
Het |
| Trav6-4 |
G |
A |
14: 53,692,237 (GRCm39) |
V115I |
probably benign |
Het |
| Trim37 |
T |
G |
11: 87,057,475 (GRCm39) |
V303G |
probably benign |
Het |
| Trpc7 |
C |
T |
13: 57,035,357 (GRCm39) |
R192Q |
probably benign |
Het |
| Ush1g |
T |
C |
11: 115,208,925 (GRCm39) |
D423G |
possibly damaging |
Het |
| Veph1 |
T |
A |
3: 66,113,048 (GRCm39) |
D252V |
possibly damaging |
Het |
| Vmn1r181 |
T |
G |
7: 23,683,978 (GRCm39) |
L148V |
probably damaging |
Het |
| Vmn2r77 |
T |
A |
7: 86,450,763 (GRCm39) |
H216Q |
probably benign |
Het |
| Zfp39 |
A |
G |
11: 58,782,156 (GRCm39) |
V202A |
probably benign |
Het |
|
| Other mutations in Vmn1r42 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02151:Vmn1r42
|
APN |
6 |
89,822,023 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02158:Vmn1r42
|
APN |
6 |
89,822,296 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02731:Vmn1r42
|
APN |
6 |
89,822,407 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL02738:Vmn1r42
|
APN |
6 |
89,821,630 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02817:Vmn1r42
|
APN |
6 |
89,822,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
volkan
|
UTSW |
6 |
89,821,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1131:Vmn1r42
|
UTSW |
6 |
89,822,551 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1500:Vmn1r42
|
UTSW |
6 |
89,822,483 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1557:Vmn1r42
|
UTSW |
6 |
89,821,733 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1561:Vmn1r42
|
UTSW |
6 |
89,822,363 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1574:Vmn1r42
|
UTSW |
6 |
89,822,363 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1574:Vmn1r42
|
UTSW |
6 |
89,822,059 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1574:Vmn1r42
|
UTSW |
6 |
89,822,059 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1857:Vmn1r42
|
UTSW |
6 |
89,821,597 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1858:Vmn1r42
|
UTSW |
6 |
89,821,597 (GRCm39) |
missense |
probably benign |
0.28 |
|
R1916:Vmn1r42
|
UTSW |
6 |
89,821,949 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2284:Vmn1r42
|
UTSW |
6 |
89,821,681 (GRCm39) |
missense |
probably benign |
0.26 |
|
R2912:Vmn1r42
|
UTSW |
6 |
89,821,688 (GRCm39) |
missense |
probably benign |
|
|
R4541:Vmn1r42
|
UTSW |
6 |
89,822,533 (GRCm39) |
missense |
probably benign |
|
|
R5085:Vmn1r42
|
UTSW |
6 |
89,821,598 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5384:Vmn1r42
|
UTSW |
6 |
89,822,366 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5616:Vmn1r42
|
UTSW |
6 |
89,822,084 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5647:Vmn1r42
|
UTSW |
6 |
89,822,314 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5867:Vmn1r42
|
UTSW |
6 |
89,821,761 (GRCm39) |
nonsense |
probably null |
|
|
R6569:Vmn1r42
|
UTSW |
6 |
89,822,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6852:Vmn1r42
|
UTSW |
6 |
89,821,769 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7054:Vmn1r42
|
UTSW |
6 |
89,822,051 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7399:Vmn1r42
|
UTSW |
6 |
89,822,495 (GRCm39) |
missense |
probably benign |
0.27 |
|
R7958:Vmn1r42
|
UTSW |
6 |
89,822,059 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Posted On |
2014-05-07 |
Incidental Mutation