Incidental Mutation 'IGL02061:Scgb2b26'
ID 185394
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Scgb2b26
Ensembl Gene ENSMUSG00000066586
Gene Name secretoglobin, family 2B, member 26
Synonyms Abpg, C2d, Abpbg26, Scgb2b4, Abpbg4
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.052) question?
Stock # IGL02061
Quality Score
Status
Chromosome 7
Chromosomal Location 33943002-33945040 bp(-) (GRCm38)
Type of Mutation missense
DNA Base Change (assembly) T to C at 33943185 bp (GRCm38)
Zygosity Heterozygous
Amino Acid Change Asparagine to Serine at position 107 (N107S)
Ref Sequence ENSEMBL: ENSMUSP00000082763 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000085623]
AlphaFold Q8JZX1
Predicted Effect probably benign
Transcript: ENSMUST00000085623
AA Change: N107S

PolyPhen 2 Score 0.162 (Sensitivity: 0.92; Specificity: 0.87)
SMART Domains Protein: ENSMUSP00000082763
Gene: ENSMUSG00000066586
AA Change: N107S

DomainStartEndE-ValueType
low complexity region 5 11 N/A INTRINSIC
Pfam:Feld-I_B 24 90 2.9e-29 PFAM
Predicted Effect noncoding transcript
Transcript: ENSMUST00000117273
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 35 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Arl15 T A 13: 113,794,657 D3E probably benign Het
Atp4a A G 7: 30,715,029 Y159C probably damaging Het
Card10 A G 15: 78,778,215 F861S probably damaging Het
Ccdc85c A G 12: 108,221,743 V279A probably damaging Het
Cndp1 G A 18: 84,634,626 R136W probably damaging Het
Eif2b3 A G 4: 117,028,411 E50G possibly damaging Het
Eva1c C T 16: 90,866,275 Q67* probably null Het
Exoc1 A G 5: 76,542,120 E169G probably damaging Het
Fam189b C T 3: 89,188,596 R545* probably null Het
Fsd2 T A 7: 81,540,424 K537* probably null Het
Gbf1 T G 19: 46,279,258 S1236A possibly damaging Het
Gpt C A 15: 76,699,417 probably benign Het
Gsap A G 5: 21,281,611 probably benign Het
Hdac6 A C X: 7,943,639 probably null Het
Ivns1abp T A 1: 151,351,573 L44Q probably damaging Het
Kcnt1 T A 2: 25,900,482 probably null Het
Kdm2b A G 5: 122,883,341 I58T probably damaging Het
Mrpl23 C T 7: 142,540,582 P76S probably benign Het
Nbea A G 3: 55,717,887 I2261T possibly damaging Het
Oasl1 G A 5: 114,923,592 V61M probably damaging Het
Olfr1288 T A 2: 111,479,269 F162I possibly damaging Het
Pabpc2 A G 18: 39,774,993 Q437R probably benign Het
Ppp1r26 T A 2: 28,450,627 C90S possibly damaging Het
Ppp3ca A G 3: 136,797,863 T66A probably benign Het
Prss55 A G 14: 64,075,743 Y231H possibly damaging Het
Psmb10 T C 8: 105,937,711 T38A probably damaging Het
Rfx5 A G 3: 94,958,481 T364A probably benign Het
Seh1l A G 18: 67,787,258 probably benign Het
Sod1 T A 16: 90,225,238 H111Q probably benign Het
Thbs2 A T 17: 14,679,914 D592E probably benign Het
Tmem67 G A 4: 12,053,526 A740V probably damaging Het
Tra2a A G 6: 49,249,098 V136A possibly damaging Het
Ttc37 T A 13: 76,129,541 probably null Het
Utp18 T C 11: 93,882,141 D158G probably benign Het
Zfp524 A G 7: 5,017,872 E133G probably damaging Het
Other mutations in Scgb2b26
AlleleSourceChrCoordTypePredicted EffectPPH Score
R0010:Scgb2b26 UTSW 7 33944349 missense probably damaging 0.98
R0010:Scgb2b26 UTSW 7 33944349 missense probably damaging 0.98
R6768:Scgb2b26 UTSW 7 33944954 missense probably damaging 1.00
R7188:Scgb2b26 UTSW 7 33944954 missense probably damaging 1.00
R7325:Scgb2b26 UTSW 7 33944357 missense probably benign 0.14
R8205:Scgb2b26 UTSW 7 33944408 missense probably benign 0.03
R8679:Scgb2b26 UTSW 7 33944359 missense probably damaging 0.99
Z1088:Scgb2b26 UTSW 7 33944367 missense probably benign 0.00
Posted On 2014-05-07