Mutagenetix > Incidental Mutations

Incidental Mutation 'IGL02061:Scgb2b26'

185394

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Scgb2b26

Ensembl Gene

ENSMUSG00000066586

Gene Name

secretoglobin, family 2B, member 26

Synonyms

Abpg, C2d, Abpbg26, Scgb2b4, Abpbg4

Accession Numbers

Is this an essential gene?

Probably non essential (E-score: 0.052) question?

Stock #

IGL02061

Quality Score

Status

Chromosome

Chromosomal Location

33943002-33945040 bp(-) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 33943185 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Asparagine to Serine at position 107 (N107S)

Ref Sequence

ENSEMBL: ENSMUSP00000082763 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000085623]

AlphaFold

Q8JZX1

Predicted Effect

probably benign
Transcript: ENSMUST00000085623
AA Change: N107S

PolyPhen 2 Score 0.162 (Sensitivity: 0.92; Specificity: 0.87)

SMART Domains

Protein: ENSMUSP00000082763
Gene: ENSMUSG00000066586
AA Change: N107S

Domain	Start	End	E-Value	Type
low complexity region	5	11	N/A	INTRINSIC
Pfam:Feld-I_B	24	90	2.9e-29	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000117273

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arl15	T	A	13: 113,794,657	D3E	probably benign	Het
Atp4a	A	G	7: 30,715,029	Y159C	probably damaging	Het
Card10	A	G	15: 78,778,215	F861S	probably damaging	Het
Ccdc85c	A	G	12: 108,221,743	V279A	probably damaging	Het
Cndp1	G	A	18: 84,634,626	R136W	probably damaging	Het
Eif2b3	A	G	4: 117,028,411	E50G	possibly damaging	Het
Eva1c	C	T	16: 90,866,275	Q67*	probably null	Het
Exoc1	A	G	5: 76,542,120	E169G	probably damaging	Het
Fam189b	C	T	3: 89,188,596	R545*	probably null	Het
Fsd2	T	A	7: 81,540,424	K537*	probably null	Het
Gbf1	T	G	19: 46,279,258	S1236A	possibly damaging	Het
Gpt	C	A	15: 76,699,417		probably benign	Het
Gsap	A	G	5: 21,281,611		probably benign	Het
Hdac6	A	C	X: 7,943,639		probably null	Het
Ivns1abp	T	A	1: 151,351,573	L44Q	probably damaging	Het
Kcnt1	T	A	2: 25,900,482		probably null	Het
Kdm2b	A	G	5: 122,883,341	I58T	probably damaging	Het
Mrpl23	C	T	7: 142,540,582	P76S	probably benign	Het
Nbea	A	G	3: 55,717,887	I2261T	possibly damaging	Het
Oasl1	G	A	5: 114,923,592	V61M	probably damaging	Het
Olfr1288	T	A	2: 111,479,269	F162I	possibly damaging	Het
Pabpc2	A	G	18: 39,774,993	Q437R	probably benign	Het
Ppp1r26	T	A	2: 28,450,627	C90S	possibly damaging	Het
Ppp3ca	A	G	3: 136,797,863	T66A	probably benign	Het
Prss55	A	G	14: 64,075,743	Y231H	possibly damaging	Het
Psmb10	T	C	8: 105,937,711	T38A	probably damaging	Het
Rfx5	A	G	3: 94,958,481	T364A	probably benign	Het
Seh1l	A	G	18: 67,787,258		probably benign	Het
Sod1	T	A	16: 90,225,238	H111Q	probably benign	Het
Thbs2	A	T	17: 14,679,914	D592E	probably benign	Het
Tmem67	G	A	4: 12,053,526	A740V	probably damaging	Het
Tra2a	A	G	6: 49,249,098	V136A	possibly damaging	Het
Ttc37	T	A	13: 76,129,541		probably null	Het
Utp18	T	C	11: 93,882,141	D158G	probably benign	Het
Zfp524	A	G	7: 5,017,872	E133G	probably damaging	Het

Other mutations in Scgb2b26

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R0010:Scgb2b26	UTSW	7	33944349	missense	probably damaging	0.98
R0010:Scgb2b26	UTSW	7	33944349	missense	probably damaging	0.98
R6768:Scgb2b26	UTSW	7	33944954	missense	probably damaging	1.00
R7188:Scgb2b26	UTSW	7	33944954	missense	probably damaging	1.00
R7325:Scgb2b26	UTSW	7	33944357	missense	probably benign	0.14
R8205:Scgb2b26	UTSW	7	33944408	missense	probably benign	0.03
R8679:Scgb2b26	UTSW	7	33944359	missense	probably damaging	0.99
Z1088:Scgb2b26	UTSW	7	33944367	missense	probably benign	0.00

Posted On

2014-05-07