Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL02051:Moxd1'

186126

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Moxd1

Ensembl Gene

ENSMUSG00000020000

Gene Name

monooxygenase, DBH-like 1

Synonyms

3230402N08Rik

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

IGL02051

Quality Score

Status

Chromosome

Chromosomal Location

24099415-24178681 bp(+) (GRCm39)

Type of Mutation

splice site (3 bp from exon)

DNA Base Change (assembly)

A to G at 24128916 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000093460 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000095784]

AlphaFold

Q9CXI3

Predicted Effect

probably null
Transcript: ENSMUST00000095784

SMART Domains

Protein: ENSMUSP00000093460
Gene: ENSMUSG00000020000

Domain	Start	End	E-Value	Type
signal peptide	1	18	N/A	INTRINSIC
DoH	59	148	7.89e-15	SMART
Pfam:Cu2_monooxygen	186	315	2.7e-50	PFAM
Pfam:Cu2_monoox_C	334	491	2.1e-48	PFAM
low complexity region	602	613	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 21 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Cacul1	T	C	19: 60,531,504 (GRCm39)	D255G	probably damaging	Het
Chi3l1	T	C	1: 134,111,887 (GRCm39)	S94P	probably damaging	Het
Defa38	A	G	8: 21,585,275 (GRCm39)		probably benign	Het
Dzip3	T	C	16: 48,792,617 (GRCm39)	T223A	probably benign	Het
Firrm	T	C	1: 163,785,091 (GRCm39)	T763A	probably benign	Het
Gfra3	T	C	18: 34,828,894 (GRCm39)	T167A	possibly damaging	Het
Glb1l3	T	C	9: 26,736,464 (GRCm39)	I533V	probably benign	Het
Gm11437	T	A	11: 84,043,592 (GRCm39)	Q233L	probably benign	Het
Hif1an	A	G	19: 44,551,829 (GRCm39)	Y93C	probably damaging	Het
Hspg2	A	G	4: 137,295,700 (GRCm39)		probably benign	Het
Ints15	A	G	5: 143,293,737 (GRCm39)	C247R	probably damaging	Het
Mak	G	A	13: 41,195,558 (GRCm39)	A385V	probably benign	Het
Mical2	G	T	7: 111,980,597 (GRCm39)	K190N	probably benign	Het
Ptpn5	A	G	7: 46,732,507 (GRCm39)		probably null	Het
Ryr1	A	G	7: 28,771,083 (GRCm39)	Y2614H	probably benign	Het
Sema3e	T	A	5: 14,274,324 (GRCm39)	Y192N	possibly damaging	Het
Smpd4	T	C	16: 17,444,382 (GRCm39)	L145P	probably damaging	Het
Tesk2	A	G	4: 116,608,381 (GRCm39)	E101G	probably damaging	Het
Vmn1r68	A	T	7: 10,261,948 (GRCm39)	V50E	probably benign	Het
Vpreb3	G	A	10: 75,784,244 (GRCm39)		probably null	Het
Vps72	T	C	3: 95,030,040 (GRCm39)	L353P	possibly damaging	Het

Other mutations in Moxd1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00091:Moxd1	APN	10	24,155,762 (GRCm39)	missense	probably damaging	1.00
IGL00227:Moxd1	APN	10	24,158,491 (GRCm39)	missense	probably damaging	1.00
IGL00331:Moxd1	APN	10	24,158,453 (GRCm39)	splice site	probably benign
IGL01074:Moxd1	APN	10	24,155,282 (GRCm39)	missense	probably benign	0.45
IGL01462:Moxd1	APN	10	24,120,286 (GRCm39)	critical splice donor site	probably null
IGL01777:Moxd1	APN	10	24,128,494 (GRCm39)	missense	probably benign	0.00
IGL02272:Moxd1	APN	10	24,158,598 (GRCm39)	nonsense	probably null
IGL02343:Moxd1	APN	10	24,155,762 (GRCm39)	missense	probably damaging	1.00
IGL02425:Moxd1	APN	10	24,155,334 (GRCm39)	missense	probably benign	0.01
IGL02448:Moxd1	APN	10	24,158,617 (GRCm39)	missense	probably damaging	0.99
IGL02452:Moxd1	APN	10	24,158,650 (GRCm39)	missense	probably damaging	1.00
IGL03301:Moxd1	APN	10	24,155,382 (GRCm39)	missense	probably damaging	0.99
R0631:Moxd1	UTSW	10	24,128,852 (GRCm39)	missense	probably damaging	1.00
R1436:Moxd1	UTSW	10	24,120,256 (GRCm39)	missense	probably damaging	1.00
R1484:Moxd1	UTSW	10	24,099,758 (GRCm39)	missense	probably damaging	1.00
R1574:Moxd1	UTSW	10	24,176,217 (GRCm39)	missense	probably damaging	1.00
R1574:Moxd1	UTSW	10	24,176,217 (GRCm39)	missense	probably damaging	1.00
R1713:Moxd1	UTSW	10	24,157,394 (GRCm39)	missense	probably damaging	1.00
R1954:Moxd1	UTSW	10	24,155,781 (GRCm39)	missense	probably benign	0.17
R3115:Moxd1	UTSW	10	24,177,429 (GRCm39)	nonsense	probably null
R3116:Moxd1	UTSW	10	24,177,429 (GRCm39)	nonsense	probably null
R5183:Moxd1	UTSW	10	24,163,034 (GRCm39)	missense	probably damaging	1.00
R5183:Moxd1	UTSW	10	24,155,445 (GRCm39)	critical splice donor site	probably null
R5322:Moxd1	UTSW	10	24,120,151 (GRCm39)	missense	possibly damaging	0.88
R5728:Moxd1	UTSW	10	24,099,581 (GRCm39)	missense	possibly damaging	0.92
R5824:Moxd1	UTSW	10	24,162,995 (GRCm39)	missense	probably damaging	1.00
R6158:Moxd1	UTSW	10	24,160,675 (GRCm39)	missense	probably damaging	1.00
R6322:Moxd1	UTSW	10	24,160,709 (GRCm39)	missense	probably damaging	1.00
R6662:Moxd1	UTSW	10	24,160,658 (GRCm39)	missense	probably damaging	1.00
R6827:Moxd1	UTSW	10	24,155,748 (GRCm39)	missense	probably benign	0.29
R6928:Moxd1	UTSW	10	24,176,186 (GRCm39)	missense	probably damaging	1.00
R7048:Moxd1	UTSW	10	24,157,374 (GRCm39)	missense	probably damaging	1.00
R7320:Moxd1	UTSW	10	24,177,363 (GRCm39)	missense	probably benign	0.05
R7736:Moxd1	UTSW	10	24,158,608 (GRCm39)	missense	probably damaging	1.00
R8060:Moxd1	UTSW	10	24,177,510 (GRCm39)	missense	unknown
R8073:Moxd1	UTSW	10	24,128,848 (GRCm39)	missense	probably damaging	1.00
R8089:Moxd1	UTSW	10	24,157,417 (GRCm39)	missense	probably benign	0.43
R8255:Moxd1	UTSW	10	24,099,700 (GRCm39)	missense	probably benign	0.02
R8314:Moxd1	UTSW	10	24,128,438 (GRCm39)	missense	possibly damaging	0.81
R9039:Moxd1	UTSW	10	24,155,251 (GRCm39)	splice site	probably benign
R9099:Moxd1	UTSW	10	24,155,762 (GRCm39)	missense	probably damaging	1.00
R9306:Moxd1	UTSW	10	24,128,824 (GRCm39)	splice site	probably benign
R9657:Moxd1	UTSW	10	24,128,485 (GRCm39)	missense	probably benign	0.16
X0063:Moxd1	UTSW	10	24,128,398 (GRCm39)	missense	probably benign	0.18
Z1177:Moxd1	UTSW	10	24,160,702 (GRCm39)	missense	probably benign

Posted On

2014-05-07