Incidental Mutation 'R1681:Cntln'
| ID |
188483 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cntln
|
| Ensembl Gene |
ENSMUSG00000038070 |
| Gene Name |
centlein, centrosomal protein |
| Synonyms |
D530005L17Rik, B430108F07Rik |
| MMRRC Submission |
039717-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.340)
|
| Stock # |
R1681 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
84802546-85050158 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 84865872 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Serine
at position 176
(L176S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130491
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000047023]
[ENSMUST00000102819]
[ENSMUST00000169371]
|
| AlphaFold |
A2AM05 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000047023
AA Change: L176S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000044138
Gene: ENSMUSG00000038070
AA Change: L176S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
24 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
86 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
198 |
219 |
1.25e-5 |
PROSPERO |
|
low complexity region
|
242 |
251 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
321 |
342 |
1.25e-5 |
PROSPERO |
|
low complexity region
|
346 |
358 |
N/A |
INTRINSIC |
|
coiled coil region
|
404 |
433 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
446 |
N/A |
INTRINSIC |
|
coiled coil region
|
458 |
481 |
N/A |
INTRINSIC |
|
coiled coil region
|
516 |
584 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
648 |
N/A |
INTRINSIC |
|
coiled coil region
|
674 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
829 |
N/A |
INTRINSIC |
|
coiled coil region
|
973 |
1114 |
N/A |
INTRINSIC |
|
low complexity region
|
1206 |
1217 |
N/A |
INTRINSIC |
|
Blast:HisKA
|
1270 |
1326 |
1e-24 |
BLAST |
|
low complexity region
|
1327 |
1348 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000102819
AA Change: L176S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000099883
Gene: ENSMUSG00000038070
AA Change: L176S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
24 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
86 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
coiled coil region
|
166 |
277 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169371
AA Change: L176S
PolyPhen 2
Score 0.996 (Sensitivity: 0.55; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000130491
Gene: ENSMUSG00000038070
AA Change: L176S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
4 |
24 |
N/A |
INTRINSIC |
|
low complexity region
|
58 |
86 |
N/A |
INTRINSIC |
|
coiled coil region
|
96 |
126 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
198 |
219 |
1.24e-5 |
PROSPERO |
|
low complexity region
|
242 |
251 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
321 |
342 |
1.24e-5 |
PROSPERO |
|
low complexity region
|
346 |
358 |
N/A |
INTRINSIC |
|
coiled coil region
|
404 |
433 |
N/A |
INTRINSIC |
|
low complexity region
|
434 |
446 |
N/A |
INTRINSIC |
|
coiled coil region
|
458 |
481 |
N/A |
INTRINSIC |
|
coiled coil region
|
516 |
584 |
N/A |
INTRINSIC |
|
coiled coil region
|
606 |
648 |
N/A |
INTRINSIC |
|
coiled coil region
|
674 |
780 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
829 |
N/A |
INTRINSIC |
|
coiled coil region
|
972 |
1113 |
N/A |
INTRINSIC |
|
low complexity region
|
1205 |
1216 |
N/A |
INTRINSIC |
|
Blast:HisKA
|
1269 |
1325 |
1e-24 |
BLAST |
|
low complexity region
|
1326 |
1347 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
T |
A |
11: 84,117,011 (GRCm39) |
I247N |
probably damaging |
Het |
| Ankle1 |
G |
T |
8: 71,860,262 (GRCm39) |
S260I |
probably benign |
Het |
| Aoc2 |
T |
C |
11: 101,216,018 (GRCm39) |
S34P |
probably benign |
Het |
| Ap1m1 |
A |
C |
8: 73,009,966 (GRCm39) |
I397L |
possibly damaging |
Het |
| Apba1 |
C |
A |
19: 23,913,925 (GRCm39) |
D649E |
probably damaging |
Het |
| Aptx |
C |
T |
4: 40,697,274 (GRCm39) |
V25M |
probably benign |
Het |
| Arhgef18 |
G |
A |
8: 3,489,645 (GRCm39) |
G326R |
probably damaging |
Het |
| Atm |
A |
C |
9: 53,433,455 (GRCm39) |
I265S |
possibly damaging |
Het |
| B3galt4 |
A |
T |
17: 34,170,187 (GRCm39) |
V17E |
probably benign |
Het |
| Bcl7a |
T |
A |
5: 123,494,086 (GRCm39) |
M86K |
possibly damaging |
Het |
| Calhm6 |
A |
G |
10: 34,003,896 (GRCm39) |
F4L |
probably benign |
Het |
| Cela3a |
T |
A |
4: 137,129,995 (GRCm39) |
|
probably null |
Het |
| Cep85 |
T |
A |
4: 133,876,039 (GRCm39) |
K456* |
probably null |
Het |
| Ces1f |
C |
A |
8: 94,002,042 (GRCm39) |
A29S |
probably benign |
Het |
| Chd9 |
A |
T |
8: 91,699,763 (GRCm39) |
I598F |
probably damaging |
Het |
| Cntn3 |
A |
T |
6: 102,147,629 (GRCm39) |
N909K |
probably damaging |
Het |
| Cntnap5b |
T |
C |
1: 100,003,832 (GRCm39) |
S271P |
probably damaging |
Het |
| Col6a3 |
T |
A |
1: 90,701,224 (GRCm39) |
H2564L |
unknown |
Het |
| Cyp2b19 |
C |
A |
7: 26,462,765 (GRCm39) |
|
probably null |
Het |
| Dapk1 |
G |
T |
13: 60,866,278 (GRCm39) |
|
probably null |
Het |
| Dnah7b |
T |
A |
1: 46,363,872 (GRCm39) |
Y3497* |
probably null |
Het |
| Duoxa2 |
T |
C |
2: 122,129,643 (GRCm39) |
|
probably null |
Het |
| Eny2 |
T |
C |
15: 44,295,874 (GRCm39) |
W42R |
probably damaging |
Het |
| Epha3 |
A |
G |
16: 63,416,091 (GRCm39) |
V635A |
probably damaging |
Het |
| Fam167b |
G |
C |
4: 129,472,069 (GRCm39) |
Q34E |
probably benign |
Het |
| Fancm |
T |
C |
12: 65,152,430 (GRCm39) |
M962T |
probably benign |
Het |
| Gimap8 |
T |
A |
6: 48,633,345 (GRCm39) |
I388N |
probably benign |
Het |
| Gpaa1 |
A |
G |
15: 76,215,653 (GRCm39) |
T22A |
probably benign |
Het |
| Hoxc11 |
T |
C |
15: 102,863,591 (GRCm39) |
S211P |
possibly damaging |
Het |
| Hsd17b12 |
T |
C |
2: 93,863,906 (GRCm39) |
N312S |
unknown |
Het |
| Idh2 |
T |
G |
7: 79,748,906 (GRCm39) |
E125A |
probably damaging |
Het |
| Igdcc4 |
A |
G |
9: 65,036,077 (GRCm39) |
Y712C |
probably damaging |
Het |
| Kank1 |
T |
C |
19: 25,387,668 (GRCm39) |
V447A |
possibly damaging |
Het |
| Kif1b |
T |
A |
4: 149,279,958 (GRCm39) |
|
probably null |
Het |
| Klc4 |
A |
T |
17: 46,947,696 (GRCm39) |
D335E |
probably damaging |
Het |
| Klhl33 |
T |
A |
14: 51,130,534 (GRCm39) |
D320V |
probably benign |
Het |
| Krt73 |
A |
T |
15: 101,710,482 (GRCm39) |
M84K |
possibly damaging |
Het |
| Kti12 |
T |
A |
4: 108,706,055 (GRCm39) |
I323N |
probably damaging |
Het |
| Kynu |
T |
C |
2: 43,569,837 (GRCm39) |
L373P |
probably damaging |
Het |
| Lats1 |
T |
C |
10: 7,581,678 (GRCm39) |
M821T |
probably damaging |
Het |
| Lnx1 |
A |
T |
5: 74,846,071 (GRCm39) |
H126Q |
probably benign |
Het |
| Lonrf2 |
G |
A |
1: 38,852,357 (GRCm39) |
P165S |
probably benign |
Het |
| Lrrc4b |
T |
A |
7: 44,110,601 (GRCm39) |
Y158N |
probably damaging |
Het |
| Lrrc74b |
C |
A |
16: 17,377,617 (GRCm39) |
R87L |
probably damaging |
Het |
| Meig1 |
T |
C |
2: 3,410,311 (GRCm39) |
D63G |
probably damaging |
Het |
| Mrpl38 |
G |
A |
11: 116,029,255 (GRCm39) |
|
probably benign |
Het |
| Mtcl2 |
T |
C |
2: 156,872,450 (GRCm39) |
T966A |
possibly damaging |
Het |
| Naip2 |
C |
T |
13: 100,298,368 (GRCm39) |
G556D |
probably benign |
Het |
| Naip2 |
T |
C |
13: 100,298,362 (GRCm39) |
E558G |
probably benign |
Het |
| Nlrp1a |
T |
A |
11: 71,033,184 (GRCm39) |
E3D |
unknown |
Het |
| Nphs2 |
T |
A |
1: 156,148,468 (GRCm39) |
D110E |
probably damaging |
Het |
| Nxn |
T |
A |
11: 76,163,290 (GRCm39) |
K244N |
probably benign |
Het |
| Oas3 |
A |
T |
5: 120,907,973 (GRCm39) |
F322L |
probably benign |
Het |
| Obscn |
T |
A |
11: 58,994,151 (GRCm39) |
Y1577F |
probably damaging |
Het |
| Or10ag57 |
G |
A |
2: 87,218,964 (GRCm39) |
R305K |
possibly damaging |
Het |
| Or8b47 |
T |
A |
9: 38,435,413 (GRCm39) |
N128K |
probably benign |
Het |
| Or8b50 |
G |
A |
9: 38,518,244 (GRCm39) |
G161D |
probably damaging |
Het |
| Or8b52 |
A |
G |
9: 38,576,616 (GRCm39) |
Y175H |
probably benign |
Het |
| Or8d2 |
T |
C |
9: 38,759,809 (GRCm39) |
M133T |
probably damaging |
Het |
| Panx1 |
T |
C |
9: 14,919,079 (GRCm39) |
D260G |
probably benign |
Het |
| Pcdhb15 |
T |
C |
18: 37,606,866 (GRCm39) |
Y33H |
probably damaging |
Het |
| Pik3ap1 |
C |
A |
19: 41,296,968 (GRCm39) |
V461F |
probably damaging |
Het |
| Plpp3 |
G |
A |
4: 105,066,002 (GRCm39) |
|
probably null |
Het |
| Prtn3 |
A |
T |
10: 79,716,375 (GRCm39) |
T61S |
probably benign |
Het |
| Psen1 |
T |
A |
12: 83,771,394 (GRCm39) |
Y225N |
probably damaging |
Het |
| Rab44 |
T |
A |
17: 29,359,098 (GRCm39) |
S429T |
possibly damaging |
Het |
| Ralgapa1 |
T |
C |
12: 55,809,388 (GRCm39) |
I462M |
probably benign |
Het |
| Rbfox3 |
T |
C |
11: 118,396,495 (GRCm39) |
N105S |
probably damaging |
Het |
| Rbm7 |
A |
C |
9: 48,401,021 (GRCm39) |
Y236D |
possibly damaging |
Het |
| Samhd1 |
T |
C |
2: 156,943,652 (GRCm39) |
T621A |
probably benign |
Het |
| Samt3 |
C |
A |
X: 85,090,256 (GRCm39) |
D49E |
probably benign |
Het |
| Sass6 |
T |
C |
3: 116,397,122 (GRCm39) |
V26A |
possibly damaging |
Het |
| Scn11a |
C |
T |
9: 119,633,478 (GRCm39) |
M418I |
possibly damaging |
Het |
| Scrib |
T |
C |
15: 75,936,416 (GRCm39) |
E480G |
probably damaging |
Het |
| Sec24a |
T |
G |
11: 51,586,016 (GRCm39) |
T1071P |
probably damaging |
Het |
| Siglecg |
A |
C |
7: 43,058,365 (GRCm39) |
E84A |
probably benign |
Het |
| Slc6a17 |
C |
T |
3: 107,381,702 (GRCm39) |
V419I |
probably damaging |
Het |
| Ssr2 |
T |
C |
3: 88,488,349 (GRCm39) |
M75T |
possibly damaging |
Het |
| Tbc1d22b |
A |
G |
17: 29,794,151 (GRCm39) |
T275A |
possibly damaging |
Het |
| Tbx15 |
T |
A |
3: 99,259,140 (GRCm39) |
|
probably null |
Het |
| Tll1 |
A |
C |
8: 64,538,585 (GRCm39) |
L353R |
possibly damaging |
Het |
| Tlr4 |
C |
T |
4: 66,759,342 (GRCm39) |
P712S |
probably damaging |
Het |
| Tmem145 |
T |
A |
7: 25,014,159 (GRCm39) |
F424L |
possibly damaging |
Het |
| Tnrc18 |
T |
C |
5: 142,759,572 (GRCm39) |
K755E |
unknown |
Het |
| Trmt44 |
A |
G |
5: 35,727,321 (GRCm39) |
I298T |
probably benign |
Het |
| Vmn1r69 |
A |
G |
7: 10,314,179 (GRCm39) |
V184A |
probably benign |
Het |
| Zfp84 |
T |
C |
7: 29,476,825 (GRCm39) |
C506R |
probably damaging |
Het |
|
| Other mutations in Cntln |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00639:Cntln
|
APN |
4 |
84,924,671 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL00743:Cntln
|
APN |
4 |
84,897,652 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL01014:Cntln
|
APN |
4 |
84,968,145 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL02217:Cntln
|
APN |
4 |
85,018,495 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02323:Cntln
|
APN |
4 |
84,968,026 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02353:Cntln
|
APN |
4 |
84,968,087 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02360:Cntln
|
APN |
4 |
84,968,087 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02616:Cntln
|
APN |
4 |
85,033,689 (GRCm39) |
critical splice donor site |
probably null |
|
|
PIT4696001:Cntln
|
UTSW |
4 |
84,892,237 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0110:Cntln
|
UTSW |
4 |
85,014,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0324:Cntln
|
UTSW |
4 |
85,010,932 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0349:Cntln
|
UTSW |
4 |
84,914,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0519:Cntln
|
UTSW |
4 |
84,923,290 (GRCm39) |
splice site |
probably benign |
|
|
R0529:Cntln
|
UTSW |
4 |
84,986,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0582:Cntln
|
UTSW |
4 |
84,802,978 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1077:Cntln
|
UTSW |
4 |
84,914,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1345:Cntln
|
UTSW |
4 |
84,892,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1457:Cntln
|
UTSW |
4 |
85,015,076 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1571:Cntln
|
UTSW |
4 |
84,865,823 (GRCm39) |
nonsense |
probably null |
|
|
R1622:Cntln
|
UTSW |
4 |
84,981,418 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1777:Cntln
|
UTSW |
4 |
85,048,916 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1808:Cntln
|
UTSW |
4 |
85,015,000 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1882:Cntln
|
UTSW |
4 |
85,019,072 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2056:Cntln
|
UTSW |
4 |
84,967,911 (GRCm39) |
missense |
probably benign |
|
|
R2965:Cntln
|
UTSW |
4 |
84,892,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2968:Cntln
|
UTSW |
4 |
84,875,504 (GRCm39) |
missense |
probably benign |
0.27 |
|
R3104:Cntln
|
UTSW |
4 |
84,875,406 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3106:Cntln
|
UTSW |
4 |
84,875,406 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R3121:Cntln
|
UTSW |
4 |
84,923,289 (GRCm39) |
splice site |
probably benign |
|
|
R3617:Cntln
|
UTSW |
4 |
84,923,214 (GRCm39) |
nonsense |
probably null |
|
|
R4009:Cntln
|
UTSW |
4 |
84,981,452 (GRCm39) |
missense |
probably benign |
0.45 |
|
R4036:Cntln
|
UTSW |
4 |
84,924,725 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4548:Cntln
|
UTSW |
4 |
85,015,079 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4592:Cntln
|
UTSW |
4 |
84,889,419 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4666:Cntln
|
UTSW |
4 |
84,889,453 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4826:Cntln
|
UTSW |
4 |
84,923,281 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4836:Cntln
|
UTSW |
4 |
84,967,957 (GRCm39) |
nonsense |
probably null |
|
|
R4856:Cntln
|
UTSW |
4 |
84,889,466 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4886:Cntln
|
UTSW |
4 |
84,889,466 (GRCm39) |
missense |
probably benign |
0.35 |
|
R4995:Cntln
|
UTSW |
4 |
84,968,120 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5090:Cntln
|
UTSW |
4 |
84,865,830 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5202:Cntln
|
UTSW |
4 |
84,889,466 (GRCm39) |
missense |
probably benign |
0.35 |
|
R5905:Cntln
|
UTSW |
4 |
84,889,410 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5953:Cntln
|
UTSW |
4 |
84,968,156 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6028:Cntln
|
UTSW |
4 |
84,889,410 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6298:Cntln
|
UTSW |
4 |
85,014,998 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6351:Cntln
|
UTSW |
4 |
85,033,591 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6371:Cntln
|
UTSW |
4 |
84,802,816 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6481:Cntln
|
UTSW |
4 |
84,985,747 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6864:Cntln
|
UTSW |
4 |
85,015,029 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6874:Cntln
|
UTSW |
4 |
84,985,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6919:Cntln
|
UTSW |
4 |
85,033,605 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7071:Cntln
|
UTSW |
4 |
85,018,622 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7113:Cntln
|
UTSW |
4 |
84,968,064 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7152:Cntln
|
UTSW |
4 |
84,802,937 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7253:Cntln
|
UTSW |
4 |
85,036,710 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7289:Cntln
|
UTSW |
4 |
84,964,540 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R7440:Cntln
|
UTSW |
4 |
84,981,453 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7670:Cntln
|
UTSW |
4 |
84,897,577 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7707:Cntln
|
UTSW |
4 |
84,802,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7895:Cntln
|
UTSW |
4 |
84,981,561 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8176:Cntln
|
UTSW |
4 |
84,806,926 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8247:Cntln
|
UTSW |
4 |
85,019,017 (GRCm39) |
missense |
probably benign |
0.39 |
|
R8264:Cntln
|
UTSW |
4 |
85,016,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8293:Cntln
|
UTSW |
4 |
84,952,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8536:Cntln
|
UTSW |
4 |
84,875,286 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8844:Cntln
|
UTSW |
4 |
84,892,234 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8924:Cntln
|
UTSW |
4 |
84,806,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8955:Cntln
|
UTSW |
4 |
84,986,110 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8960:Cntln
|
UTSW |
4 |
85,018,961 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8979:Cntln
|
UTSW |
4 |
85,048,910 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9255:Cntln
|
UTSW |
4 |
85,019,103 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9314:Cntln
|
UTSW |
4 |
84,924,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9353:Cntln
|
UTSW |
4 |
84,802,597 (GRCm39) |
unclassified |
probably benign |
|
|
R9361:Cntln
|
UTSW |
4 |
84,968,151 (GRCm39) |
missense |
probably benign |
0.23 |
|
R9376:Cntln
|
UTSW |
4 |
84,875,258 (GRCm39) |
missense |
probably benign |
0.24 |
|
R9382:Cntln
|
UTSW |
4 |
84,968,318 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9471:Cntln
|
UTSW |
4 |
84,968,019 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9478:Cntln
|
UTSW |
4 |
84,897,630 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9527:Cntln
|
UTSW |
4 |
84,892,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9788:Cntln
|
UTSW |
4 |
84,968,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9793:Cntln
|
UTSW |
4 |
84,985,798 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGTGGACATTTAAAGGAGCGGC -3'
(R):5'- ACCCTCACAGGCTCATTAGATGGAG -3'
Sequencing Primer
(F):5'- ggctgggagagtggtagag -3'
(R):5'- ACACCTTGTTAAGCATCTGATTG -3'
|
| Posted On |
2014-05-09 |
Incidental Mutation