Incidental Mutation 'R1682:Cep295'
| ID |
189250 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cep295
|
| Ensembl Gene |
ENSMUSG00000046111 |
| Gene Name |
centrosomal protein 295 |
| Synonyms |
5830418K08Rik, LOC382128 |
| MMRRC Submission |
039718-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.952)
|
| Stock # |
R1682 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
15228211-15269084 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 15245217 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Valine
at position 1080
(M1080V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096578
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098979]
[ENSMUST00000161132]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000058041
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000059410
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000066038
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098979
AA Change: M1080V
PolyPhen 2
Score 0.023 (Sensitivity: 0.95; Specificity: 0.81)
|
| SMART Domains |
Protein: ENSMUSP00000096578
Gene: ENSMUSG00000046111
AA Change: M1080V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
159 |
175 |
N/A |
INTRINSIC |
|
coiled coil region
|
258 |
288 |
N/A |
INTRINSIC |
|
coiled coil region
|
536 |
583 |
N/A |
INTRINSIC |
|
coiled coil region
|
861 |
889 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
890 |
1104 |
6.8e-5 |
PROSPERO |
|
internal_repeat_1
|
1277 |
1489 |
6.8e-5 |
PROSPERO |
|
low complexity region
|
1537 |
1548 |
N/A |
INTRINSIC |
|
low complexity region
|
1611 |
1625 |
N/A |
INTRINSIC |
|
coiled coil region
|
1707 |
1736 |
N/A |
INTRINSIC |
|
low complexity region
|
2003 |
2018 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000160946
|
| SMART Domains |
Protein: ENSMUSP00000125494
Gene: ENSMUSG00000046111
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
92 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
282 |
293 |
N/A |
INTRINSIC |
|
low complexity region
|
356 |
370 |
N/A |
INTRINSIC |
|
coiled coil region
|
451 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
828 |
843 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161132
AA Change: M1080V
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000123788
Gene: ENSMUSG00000046111
AA Change: M1080V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
coiled coil region
|
1300 |
1327 |
N/A |
INTRINSIC |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2050 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000161795
AA Change: M1032V
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000125035
Gene: ENSMUSG00000046111
AA Change: M1032V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
111 |
127 |
N/A |
INTRINSIC |
|
coiled coil region
|
210 |
240 |
N/A |
INTRINSIC |
|
coiled coil region
|
488 |
535 |
N/A |
INTRINSIC |
|
coiled coil region
|
813 |
841 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
842 |
1056 |
7.14e-5 |
PROSPERO |
|
internal_repeat_1
|
1229 |
1441 |
7.14e-5 |
PROSPERO |
|
low complexity region
|
1489 |
1500 |
N/A |
INTRINSIC |
|
low complexity region
|
1563 |
1577 |
N/A |
INTRINSIC |
|
coiled coil region
|
1659 |
1688 |
N/A |
INTRINSIC |
|
low complexity region
|
1955 |
1970 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162264
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 88 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acaca |
A |
G |
11: 84,283,043 (GRCm39) |
D2203G |
probably benign |
Het |
| Acin1 |
A |
G |
14: 54,901,175 (GRCm39) |
S629P |
probably damaging |
Het |
| Agbl2 |
T |
A |
2: 90,614,434 (GRCm39) |
I22N |
probably benign |
Het |
| Ank1 |
A |
G |
8: 23,599,343 (GRCm39) |
E796G |
probably damaging |
Het |
| Ankrd13d |
A |
G |
19: 4,332,961 (GRCm39) |
L13P |
probably damaging |
Het |
| Ankrd36 |
T |
C |
11: 5,557,143 (GRCm39) |
S364P |
possibly damaging |
Het |
| Ap2a1 |
T |
C |
7: 44,565,362 (GRCm39) |
T126A |
probably benign |
Het |
| Apob |
A |
G |
12: 8,062,365 (GRCm39) |
I3616V |
probably benign |
Het |
| Arl5a |
A |
T |
2: 52,306,214 (GRCm39) |
N39K |
probably benign |
Het |
| Baiap2 |
G |
A |
11: 119,888,366 (GRCm39) |
R334H |
probably damaging |
Het |
| Bbox1 |
T |
A |
2: 110,122,893 (GRCm39) |
N132I |
possibly damaging |
Het |
| Bcl11b |
A |
G |
12: 107,882,908 (GRCm39) |
L469P |
probably damaging |
Het |
| Brca1 |
A |
G |
11: 101,416,391 (GRCm39) |
I581T |
probably damaging |
Het |
| Cacng2 |
T |
C |
15: 78,002,997 (GRCm39) |
Y32C |
probably damaging |
Het |
| Capn9 |
G |
T |
8: 125,338,304 (GRCm39) |
|
probably null |
Het |
| Cdh18 |
A |
G |
15: 23,400,671 (GRCm39) |
T290A |
probably benign |
Het |
| Cdk5rap2 |
C |
T |
4: 70,220,387 (GRCm39) |
V593I |
possibly damaging |
Het |
| Cep128 |
G |
C |
12: 91,197,596 (GRCm39) |
D91E |
probably damaging |
Het |
| Coq8b |
T |
A |
7: 26,939,549 (GRCm39) |
M193K |
probably benign |
Het |
| Csn1s2b |
A |
G |
5: 87,970,162 (GRCm39) |
Y131C |
probably damaging |
Het |
| D130043K22Rik |
T |
C |
13: 25,066,539 (GRCm39) |
S779P |
probably damaging |
Het |
| Dgat1 |
C |
T |
15: 76,387,219 (GRCm39) |
C356Y |
probably benign |
Het |
| Dipk1c |
A |
T |
18: 84,754,988 (GRCm39) |
I155F |
possibly damaging |
Het |
| Dnah12 |
A |
T |
14: 26,500,840 (GRCm39) |
T1543S |
possibly damaging |
Het |
| Dock3 |
T |
C |
9: 106,851,040 (GRCm39) |
S821G |
probably damaging |
Het |
| Dock4 |
G |
A |
12: 40,775,779 (GRCm39) |
C574Y |
probably damaging |
Het |
| Dr1 |
T |
C |
5: 108,417,604 (GRCm39) |
I50T |
probably damaging |
Het |
| Dzip3 |
A |
T |
16: 48,778,780 (GRCm39) |
|
probably null |
Het |
| Eln |
C |
A |
5: 134,732,636 (GRCm39) |
*861L |
probably null |
Het |
| Eml6 |
T |
A |
11: 29,709,065 (GRCm39) |
H24L |
probably benign |
Het |
| Eps8l3 |
A |
C |
3: 107,798,622 (GRCm39) |
T503P |
possibly damaging |
Het |
| Fgf1 |
C |
A |
18: 38,974,985 (GRCm39) |
D155Y |
possibly damaging |
Het |
| Fkbp15 |
A |
T |
4: 62,242,431 (GRCm39) |
M507K |
probably damaging |
Het |
| Flnb |
A |
T |
14: 7,913,121 (GRCm38) |
R1463S |
probably benign |
Het |
| Fras1 |
C |
T |
5: 96,793,732 (GRCm39) |
T1018I |
probably benign |
Het |
| Gm10803 |
T |
A |
2: 93,394,533 (GRCm39) |
C102S |
probably damaging |
Het |
| Gpatch1 |
C |
A |
7: 35,002,812 (GRCm39) |
V233L |
possibly damaging |
Het |
| Gramd1a |
T |
C |
7: 30,842,325 (GRCm39) |
|
probably null |
Het |
| Gsk3a |
T |
C |
7: 24,935,133 (GRCm39) |
T106A |
possibly damaging |
Het |
| Hap1 |
A |
G |
11: 100,240,302 (GRCm39) |
V136A |
possibly damaging |
Het |
| Helq |
A |
T |
5: 100,940,679 (GRCm39) |
S307T |
probably benign |
Het |
| Herc2 |
T |
A |
7: 55,738,148 (GRCm39) |
S264T |
possibly damaging |
Het |
| Htr4 |
A |
G |
18: 62,561,137 (GRCm39) |
M133V |
possibly damaging |
Het |
| Iqca1 |
C |
A |
1: 90,070,453 (GRCm39) |
G133V |
probably null |
Het |
| Jakmip2 |
A |
G |
18: 43,714,896 (GRCm39) |
|
probably null |
Het |
| Ldhd |
T |
A |
8: 112,354,745 (GRCm39) |
S358C |
possibly damaging |
Het |
| Lrp1 |
A |
T |
10: 127,410,201 (GRCm39) |
V1515E |
probably damaging |
Het |
| Ltbp3 |
A |
G |
19: 5,801,782 (GRCm39) |
D700G |
probably benign |
Het |
| Magel2 |
T |
G |
7: 62,029,983 (GRCm39) |
S962R |
unknown |
Het |
| Map2 |
A |
C |
1: 66,454,781 (GRCm39) |
|
probably null |
Het |
| Map3k1 |
T |
A |
13: 111,893,684 (GRCm39) |
E704V |
probably damaging |
Het |
| Mrpl39 |
A |
T |
16: 84,527,347 (GRCm39) |
V180D |
probably damaging |
Het |
| Myef2 |
T |
C |
2: 124,939,978 (GRCm39) |
M383V |
probably damaging |
Het |
| Myh3 |
A |
G |
11: 66,979,891 (GRCm39) |
Y610C |
probably damaging |
Het |
| Or10ak7 |
A |
G |
4: 118,791,778 (GRCm39) |
L89P |
probably damaging |
Het |
| Or51h1 |
T |
C |
7: 102,308,904 (GRCm39) |
V292A |
probably damaging |
Het |
| Or8g54 |
T |
A |
9: 39,706,954 (GRCm39) |
Y94* |
probably null |
Het |
| Oxtr |
C |
T |
6: 112,454,138 (GRCm39) |
R42Q |
probably benign |
Het |
| Pabpc1 |
T |
A |
15: 36,605,785 (GRCm39) |
N135I |
possibly damaging |
Het |
| Pcsk6 |
T |
A |
7: 65,559,976 (GRCm39) |
H100Q |
probably damaging |
Het |
| Pdss1 |
A |
G |
2: 22,805,531 (GRCm39) |
K270E |
probably damaging |
Het |
| Pigx |
A |
T |
16: 31,906,268 (GRCm39) |
S18T |
possibly damaging |
Het |
| Plbd2 |
T |
A |
5: 120,623,849 (GRCm39) |
T558S |
probably damaging |
Het |
| Plppr1 |
A |
T |
4: 49,325,617 (GRCm39) |
|
probably null |
Het |
| Plppr2 |
T |
A |
9: 21,855,717 (GRCm39) |
V230E |
possibly damaging |
Het |
| Pola2 |
A |
G |
19: 6,003,091 (GRCm39) |
|
probably null |
Het |
| Ppp2r3d |
A |
G |
9: 101,089,505 (GRCm39) |
S273P |
probably benign |
Het |
| Prkdc |
A |
G |
16: 15,494,853 (GRCm39) |
E741G |
probably benign |
Het |
| Prom2 |
C |
A |
2: 127,382,082 (GRCm39) |
V111L |
possibly damaging |
Het |
| Rapgef4 |
A |
G |
2: 72,056,912 (GRCm39) |
D557G |
possibly damaging |
Het |
| Rgs10 |
T |
C |
7: 127,975,694 (GRCm39) |
T158A |
probably benign |
Het |
| Rnf123 |
A |
C |
9: 107,954,597 (GRCm39) |
Y40D |
probably benign |
Het |
| Rnf14 |
A |
G |
18: 38,441,242 (GRCm39) |
T211A |
probably benign |
Het |
| Rp1l1 |
T |
A |
14: 64,266,417 (GRCm39) |
S668T |
probably damaging |
Het |
| Sema6d |
T |
A |
2: 124,507,069 (GRCm39) |
L946Q |
probably benign |
Het |
| Sgcd |
T |
G |
11: 47,085,869 (GRCm39) |
K94Q |
probably benign |
Het |
| Skor2 |
A |
T |
18: 76,947,211 (GRCm39) |
D311V |
unknown |
Het |
| Slc34a1 |
A |
T |
13: 23,996,623 (GRCm39) |
I43F |
probably damaging |
Het |
| Spdye4c |
C |
A |
2: 128,434,542 (GRCm39) |
P40T |
probably damaging |
Het |
| Srp72 |
C |
A |
5: 77,135,717 (GRCm39) |
Q216K |
possibly damaging |
Het |
| Tmem62 |
C |
T |
2: 120,837,538 (GRCm39) |
T485I |
probably benign |
Het |
| Tmem94 |
G |
T |
11: 115,681,056 (GRCm39) |
V432L |
probably damaging |
Het |
| Trio |
T |
C |
15: 27,744,232 (GRCm39) |
|
probably null |
Het |
| Uggt2 |
A |
T |
14: 119,292,055 (GRCm39) |
D581E |
probably benign |
Het |
| Unc5d |
T |
A |
8: 29,249,109 (GRCm39) |
S319C |
probably damaging |
Het |
| Vmn1r211 |
T |
C |
13: 23,035,813 (GRCm39) |
I285V |
probably damaging |
Het |
| Vmn2r68 |
A |
G |
7: 84,882,574 (GRCm39) |
Y393H |
possibly damaging |
Het |
| Vmn2r99 |
A |
C |
17: 19,598,207 (GRCm39) |
N77T |
probably damaging |
Het |
|
| Other mutations in Cep295 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Cep295
|
APN |
9 |
15,237,368 (GRCm39) |
splice site |
probably null |
|
|
IGL00769:Cep295
|
APN |
9 |
15,237,440 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00771:Cep295
|
APN |
9 |
15,233,861 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00850:Cep295
|
APN |
9 |
15,234,148 (GRCm39) |
missense |
probably benign |
0.36 |
|
IGL01505:Cep295
|
APN |
9 |
15,229,345 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL01510:Cep295
|
APN |
9 |
15,265,922 (GRCm39) |
nonsense |
probably null |
|
|
IGL01759:Cep295
|
APN |
9 |
15,234,855 (GRCm39) |
splice site |
probably null |
|
|
IGL02415:Cep295
|
APN |
9 |
15,264,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02447:Cep295
|
APN |
9 |
15,243,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02502:Cep295
|
APN |
9 |
15,262,209 (GRCm39) |
splice site |
probably benign |
|
|
IGL02665:Cep295
|
APN |
9 |
15,237,928 (GRCm39) |
splice site |
probably benign |
|
|
IGL02718:Cep295
|
APN |
9 |
15,237,049 (GRCm39) |
splice site |
probably null |
|
|
IGL02995:Cep295
|
APN |
9 |
15,244,608 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03024:Cep295
|
APN |
9 |
15,236,868 (GRCm39) |
missense |
probably benign |
|
|
R0196:Cep295
|
UTSW |
9 |
15,249,509 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0398:Cep295
|
UTSW |
9 |
15,266,032 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0595:Cep295
|
UTSW |
9 |
15,243,487 (GRCm39) |
nonsense |
probably null |
|
|
R0610:Cep295
|
UTSW |
9 |
15,234,050 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0616:Cep295
|
UTSW |
9 |
15,243,618 (GRCm39) |
nonsense |
probably null |
|
|
R0840:Cep295
|
UTSW |
9 |
15,245,611 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1215:Cep295
|
UTSW |
9 |
15,239,178 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1376:Cep295
|
UTSW |
9 |
15,252,164 (GRCm39) |
splice site |
probably benign |
|
|
R1381:Cep295
|
UTSW |
9 |
15,233,861 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1484:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1557:Cep295
|
UTSW |
9 |
15,243,306 (GRCm39) |
nonsense |
probably null |
|
|
R1655:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1700:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1734:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1736:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1743:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1765:Cep295
|
UTSW |
9 |
15,239,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1889:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1895:Cep295
|
UTSW |
9 |
15,243,399 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1994:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1995:Cep295
|
UTSW |
9 |
15,252,179 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2071:Cep295
|
UTSW |
9 |
15,252,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2161:Cep295
|
UTSW |
9 |
15,264,354 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2195:Cep295
|
UTSW |
9 |
15,243,617 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2354:Cep295
|
UTSW |
9 |
15,246,080 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2427:Cep295
|
UTSW |
9 |
15,245,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2992:Cep295
|
UTSW |
9 |
15,244,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3873:Cep295
|
UTSW |
9 |
15,244,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3981:Cep295
|
UTSW |
9 |
15,228,363 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R4201:Cep295
|
UTSW |
9 |
15,243,834 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4297:Cep295
|
UTSW |
9 |
15,233,950 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4543:Cep295
|
UTSW |
9 |
15,246,549 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R4584:Cep295
|
UTSW |
9 |
15,246,095 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R4724:Cep295
|
UTSW |
9 |
15,242,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4878:Cep295
|
UTSW |
9 |
15,246,252 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4884:Cep295
|
UTSW |
9 |
15,263,056 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4934:Cep295
|
UTSW |
9 |
15,244,456 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4990:Cep295
|
UTSW |
9 |
15,243,434 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5057:Cep295
|
UTSW |
9 |
15,233,979 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5153:Cep295
|
UTSW |
9 |
15,268,925 (GRCm39) |
missense |
probably benign |
0.32 |
|
R5180:Cep295
|
UTSW |
9 |
15,243,416 (GRCm39) |
missense |
probably benign |
|
|
R5285:Cep295
|
UTSW |
9 |
15,233,887 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5360:Cep295
|
UTSW |
9 |
15,238,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5419:Cep295
|
UTSW |
9 |
15,235,533 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5432:Cep295
|
UTSW |
9 |
15,262,991 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5625:Cep295
|
UTSW |
9 |
15,252,187 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5637:Cep295
|
UTSW |
9 |
15,245,108 (GRCm39) |
splice site |
probably null |
|
|
R5645:Cep295
|
UTSW |
9 |
15,246,404 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5645:Cep295
|
UTSW |
9 |
15,244,090 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5678:Cep295
|
UTSW |
9 |
15,234,154 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5688:Cep295
|
UTSW |
9 |
15,243,282 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5807:Cep295
|
UTSW |
9 |
15,243,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5824:Cep295
|
UTSW |
9 |
15,236,952 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5837:Cep295
|
UTSW |
9 |
15,258,280 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5915:Cep295
|
UTSW |
9 |
15,252,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5988:Cep295
|
UTSW |
9 |
15,252,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6239:Cep295
|
UTSW |
9 |
15,233,927 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Cep295
|
UTSW |
9 |
15,246,210 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6383:Cep295
|
UTSW |
9 |
15,244,050 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6737:Cep295
|
UTSW |
9 |
15,243,647 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R6929:Cep295
|
UTSW |
9 |
15,244,358 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7428:Cep295
|
UTSW |
9 |
15,244,794 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7697:Cep295
|
UTSW |
9 |
15,266,006 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7963:Cep295
|
UTSW |
9 |
15,244,737 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8055:Cep295
|
UTSW |
9 |
15,244,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8069:Cep295
|
UTSW |
9 |
15,233,882 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8092:Cep295
|
UTSW |
9 |
15,244,278 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8117:Cep295
|
UTSW |
9 |
15,245,660 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8140:Cep295
|
UTSW |
9 |
15,252,829 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8178:Cep295
|
UTSW |
9 |
15,244,836 (GRCm39) |
missense |
|
|
|
R8323:Cep295
|
UTSW |
9 |
15,264,357 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8323:Cep295
|
UTSW |
9 |
15,249,529 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R8339:Cep295
|
UTSW |
9 |
15,236,846 (GRCm39) |
missense |
|
|
|
R8351:Cep295
|
UTSW |
9 |
15,234,202 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8367:Cep295
|
UTSW |
9 |
15,245,826 (GRCm39) |
missense |
probably benign |
0.09 |
|
R8725:Cep295
|
UTSW |
9 |
15,243,715 (GRCm39) |
nonsense |
probably null |
|
|
R8919:Cep295
|
UTSW |
9 |
15,238,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Cep295
|
UTSW |
9 |
15,244,264 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9054:Cep295
|
UTSW |
9 |
15,235,551 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9088:Cep295
|
UTSW |
9 |
15,233,815 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9159:Cep295
|
UTSW |
9 |
15,252,904 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9243:Cep295
|
UTSW |
9 |
15,243,605 (GRCm39) |
missense |
probably benign |
0.36 |
|
R9408:Cep295
|
UTSW |
9 |
15,244,619 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9424:Cep295
|
UTSW |
9 |
15,244,499 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9455:Cep295
|
UTSW |
9 |
15,245,046 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9607:Cep295
|
UTSW |
9 |
15,234,009 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9648:Cep295
|
UTSW |
9 |
15,234,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9659:Cep295
|
UTSW |
9 |
15,233,846 (GRCm39) |
missense |
probably benign |
0.19 |
|
R9731:Cep295
|
UTSW |
9 |
15,245,262 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
X0065:Cep295
|
UTSW |
9 |
15,234,187 (GRCm39) |
missense |
probably benign |
0.36 |
|
Z1176:Cep295
|
UTSW |
9 |
15,268,993 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1177:Cep295
|
UTSW |
9 |
15,242,113 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- CTCAGATGAATACACGTCCTGGAGC -3'
(R):5'- GGTCTTCTTTGCCACATCAGGTAGC -3'
Sequencing Primer
(F):5'- GTCCTGGAGCCGCTTAG -3'
(R):5'- CAGGTAGCTCAGCAGTCATTTAG -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation