Incidental Mutation 'R1707:Tnn'
| ID |
190110 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
039740-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.396)
|
| Stock # |
R1707 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 159972714 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 296
(Y296C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039178
AA Change: Y296C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: Y296C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000131919
AA Change: Y296C
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: Y296C
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.2142 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.9%
|
| Validation Efficiency |
96% (82/85) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930523C07Rik |
A |
T |
1: 159,898,372 (GRCm39) |
|
probably benign |
Het |
| 4931429P17Rik |
A |
G |
13: 48,114,481 (GRCm39) |
|
noncoding transcript |
Het |
| Acox3 |
T |
A |
5: 35,758,908 (GRCm39) |
I373N |
possibly damaging |
Het |
| Adgrb1 |
G |
T |
15: 74,401,192 (GRCm39) |
A63S |
probably damaging |
Het |
| Alkbh2 |
C |
T |
5: 114,262,287 (GRCm39) |
E148K |
probably damaging |
Het |
| Aplp2 |
A |
T |
9: 31,062,215 (GRCm39) |
H692Q |
probably damaging |
Het |
| Arhgap24 |
T |
C |
5: 103,039,953 (GRCm39) |
S297P |
probably benign |
Het |
| Arhgap9 |
C |
T |
10: 127,164,758 (GRCm39) |
P561S |
probably benign |
Het |
| Arhgef10l |
T |
G |
4: 140,291,600 (GRCm39) |
D62A |
probably damaging |
Het |
| Asb14 |
T |
G |
14: 26,623,079 (GRCm39) |
F150L |
probably benign |
Het |
| Atp8b3 |
A |
T |
10: 80,357,635 (GRCm39) |
|
probably null |
Het |
| Atrnl1 |
A |
G |
19: 57,675,169 (GRCm39) |
D686G |
probably benign |
Het |
| Bmpr1a |
A |
T |
14: 34,147,098 (GRCm39) |
|
probably benign |
Het |
| Cc2d2a |
T |
A |
5: 43,881,030 (GRCm39) |
|
probably null |
Het |
| Ccin |
T |
A |
4: 43,983,947 (GRCm39) |
I118N |
probably benign |
Het |
| Cd8b1 |
G |
A |
6: 71,303,168 (GRCm39) |
G81D |
probably damaging |
Het |
| Cep126 |
G |
A |
9: 8,100,383 (GRCm39) |
S717L |
probably benign |
Het |
| Cip2a |
A |
C |
16: 48,838,767 (GRCm39) |
Q861H |
probably damaging |
Het |
| Colgalt2 |
C |
T |
1: 152,276,114 (GRCm39) |
R76W |
probably damaging |
Het |
| Copg1 |
A |
T |
6: 87,882,192 (GRCm39) |
T596S |
probably benign |
Het |
| Cpb1 |
G |
A |
3: 20,329,655 (GRCm39) |
R24W |
probably damaging |
Het |
| Csad |
T |
A |
15: 102,088,407 (GRCm39) |
D134V |
probably damaging |
Het |
| Dchs2 |
A |
G |
3: 83,034,912 (GRCm39) |
|
probably benign |
Het |
| Ddb2 |
A |
G |
2: 91,064,554 (GRCm39) |
W119R |
probably damaging |
Het |
| Dhx57 |
A |
T |
17: 80,582,655 (GRCm39) |
S317T |
probably damaging |
Het |
| Dlc1 |
A |
G |
8: 37,404,763 (GRCm39) |
V342A |
probably benign |
Het |
| Dpp4 |
G |
A |
2: 62,189,679 (GRCm39) |
|
probably benign |
Het |
| Dst |
G |
T |
1: 34,206,727 (GRCm39) |
W1005L |
probably damaging |
Het |
| Ehmt1 |
T |
C |
2: 24,695,150 (GRCm39) |
M989V |
probably benign |
Het |
| Entr1 |
T |
A |
2: 26,277,618 (GRCm39) |
N69Y |
probably damaging |
Het |
| Gm5422 |
G |
A |
10: 31,124,458 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9944 |
A |
G |
4: 144,179,833 (GRCm39) |
|
probably benign |
Het |
| Gtf2ird2 |
T |
C |
5: 134,245,829 (GRCm39) |
Y696H |
probably damaging |
Het |
| H2-M11 |
T |
G |
17: 36,859,658 (GRCm39) |
V217G |
probably damaging |
Het |
| Hunk |
C |
T |
16: 90,183,295 (GRCm39) |
|
probably benign |
Het |
| Impg1 |
T |
C |
9: 80,285,799 (GRCm39) |
|
probably null |
Het |
| Ints11 |
T |
G |
4: 155,959,655 (GRCm39) |
D87E |
probably benign |
Het |
| Intu |
T |
A |
3: 40,595,073 (GRCm39) |
S21T |
probably benign |
Het |
| Intu |
C |
A |
3: 40,637,931 (GRCm39) |
D472E |
possibly damaging |
Het |
| Kbtbd3 |
T |
A |
9: 4,316,985 (GRCm39) |
N45K |
probably benign |
Het |
| Kif1c |
C |
T |
11: 70,619,223 (GRCm39) |
L953F |
probably damaging |
Het |
| Klrg2 |
C |
G |
6: 38,613,729 (GRCm39) |
E91D |
possibly damaging |
Het |
| Lamc3 |
T |
C |
2: 31,802,141 (GRCm39) |
|
probably null |
Het |
| Magi2 |
T |
G |
5: 20,420,491 (GRCm39) |
M309R |
probably damaging |
Het |
| Magohb |
G |
A |
6: 131,261,600 (GRCm39) |
P147S |
probably damaging |
Het |
| Mdn1 |
A |
G |
4: 32,693,504 (GRCm39) |
D1043G |
probably damaging |
Het |
| Mtmr3 |
T |
C |
11: 4,454,095 (GRCm39) |
D203G |
probably damaging |
Het |
| Mvp |
C |
T |
7: 126,600,744 (GRCm39) |
V86I |
probably benign |
Het |
| Naip5 |
A |
T |
13: 100,379,363 (GRCm39) |
F226I |
probably damaging |
Het |
| Nasp |
T |
A |
4: 116,476,133 (GRCm39) |
Q51L |
probably damaging |
Het |
| Nf1 |
T |
A |
11: 79,426,430 (GRCm39) |
F1594I |
probably damaging |
Het |
| Nod2 |
A |
C |
8: 89,397,104 (GRCm39) |
E816A |
possibly damaging |
Het |
| Nom1 |
G |
A |
5: 29,640,316 (GRCm39) |
S214N |
probably damaging |
Het |
| Or2l13b |
T |
C |
16: 19,348,927 (GRCm39) |
T248A |
probably benign |
Het |
| Or8c9 |
T |
A |
9: 38,241,197 (GRCm39) |
F105I |
probably damaging |
Het |
| Parp14 |
A |
C |
16: 35,678,219 (GRCm39) |
L583R |
probably damaging |
Het |
| Pclo |
T |
C |
5: 14,763,238 (GRCm39) |
S3904P |
unknown |
Het |
| Pkhd1 |
T |
A |
1: 20,621,064 (GRCm39) |
|
probably benign |
Het |
| Plaat1 |
A |
G |
16: 29,046,978 (GRCm39) |
K166E |
probably damaging |
Het |
| Polr1e |
A |
C |
4: 45,027,469 (GRCm39) |
D233A |
probably damaging |
Het |
| Prr29 |
T |
C |
11: 106,267,509 (GRCm39) |
V124A |
probably damaging |
Het |
| Rasgrp1 |
A |
T |
2: 117,129,028 (GRCm39) |
V197E |
probably damaging |
Het |
| Rgma |
A |
T |
7: 73,067,707 (GRCm39) |
T415S |
unknown |
Het |
| Sacs |
G |
T |
14: 61,447,211 (GRCm39) |
V3086L |
probably benign |
Het |
| Sash1 |
A |
G |
10: 8,606,141 (GRCm39) |
S750P |
probably benign |
Het |
| Scpppq1 |
T |
A |
5: 104,222,099 (GRCm39) |
|
probably benign |
Het |
| Sema6a |
A |
T |
18: 47,416,512 (GRCm39) |
S372T |
probably benign |
Het |
| Sis |
A |
G |
3: 72,816,420 (GRCm39) |
|
probably benign |
Het |
| Skint8 |
T |
A |
4: 111,796,769 (GRCm39) |
V291D |
probably damaging |
Het |
| Slc12a8 |
A |
G |
16: 33,371,377 (GRCm39) |
N171S |
probably damaging |
Het |
| Slc25a40 |
G |
A |
5: 8,490,793 (GRCm39) |
|
probably null |
Het |
| Spag6l |
A |
T |
16: 16,598,492 (GRCm39) |
I333N |
probably benign |
Het |
| Sspo |
T |
A |
6: 48,454,811 (GRCm39) |
F2999L |
probably damaging |
Het |
| Stambpl1 |
A |
C |
19: 34,216,221 (GRCm39) |
T363P |
probably damaging |
Het |
| Tenm4 |
A |
T |
7: 96,537,892 (GRCm39) |
N1785Y |
probably damaging |
Het |
| Tln2 |
C |
T |
9: 67,283,089 (GRCm39) |
S293N |
probably benign |
Het |
| Tmed3 |
G |
A |
9: 89,584,833 (GRCm39) |
L141F |
probably damaging |
Het |
| Tmem30c |
G |
T |
16: 57,086,843 (GRCm39) |
T320K |
possibly damaging |
Het |
| Ttn |
C |
T |
2: 76,620,430 (GRCm39) |
A15802T |
probably damaging |
Het |
| Usp53 |
T |
C |
3: 122,741,049 (GRCm39) |
M734V |
probably benign |
Het |
| Vmn1r24 |
A |
G |
6: 57,933,497 (GRCm39) |
I7T |
probably benign |
Het |
| Vmn1r74 |
T |
A |
7: 11,581,504 (GRCm39) |
V268E |
probably damaging |
Het |
| Xirp1 |
A |
T |
9: 119,847,841 (GRCm39) |
H347Q |
possibly damaging |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
159,975,338 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4868:Tnn
|
UTSW |
1 |
159,958,443 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
159,953,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
159,972,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
159,973,592 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATGTTCCTCACCTGTGGTGGCAAG -3'
(R):5'- GGTGTGATACGTAATCTGCACCCTG -3'
Sequencing Primer
(F):5'- ACCTGTGGTGGCAAGTAGATG -3'
(R):5'- CAGCCTTAAGTGAATAGTAGGTGC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation