Incidental Mutation 'R1711:Ranbp2'
| ID |
190588 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ranbp2
|
| Ensembl Gene |
ENSMUSG00000003226 |
| Gene Name |
RAN binding protein 2 |
| Synonyms |
A430087B05Rik |
| MMRRC Submission |
039744-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1711 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
10 |
| Chromosomal Location |
58446920-58494356 bp(+) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 58460519 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 326
(V326A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000003310
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000003310]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000003310
AA Change: V326A
PolyPhen 2
Score 0.108 (Sensitivity: 0.93; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000003310
Gene: ENSMUSG00000003226
AA Change: V326A
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:TPR_1
|
60 |
93 |
1.8e-7 |
PFAM |
|
Pfam:TPR_8
|
60 |
93 |
8.9e-6 |
PFAM |
|
low complexity region
|
235 |
247 |
N/A |
INTRINSIC |
|
low complexity region
|
778 |
801 |
N/A |
INTRINSIC |
|
coiled coil region
|
808 |
832 |
N/A |
INTRINSIC |
|
RanBD
|
1166 |
1295 |
6.47e-64 |
SMART |
|
ZnF_RBZ
|
1348 |
1372 |
5.49e-2 |
SMART |
|
ZnF_RBZ
|
1412 |
1436 |
3.06e-6 |
SMART |
|
ZnF_RBZ
|
1471 |
1495 |
4.16e-8 |
SMART |
|
ZnF_RBZ
|
1500 |
1524 |
4.57e-5 |
SMART |
|
ZnF_RBZ
|
1560 |
1584 |
3.52e-6 |
SMART |
|
ZnF_RBZ
|
1619 |
1643 |
1.35e-7 |
SMART |
|
RanBD
|
1850 |
1979 |
2.84e-60 |
SMART |
|
low complexity region
|
2034 |
2048 |
N/A |
INTRINSIC |
|
low complexity region
|
2069 |
2090 |
N/A |
INTRINSIC |
|
low complexity region
|
2106 |
2121 |
N/A |
INTRINSIC |
|
RanBD
|
2147 |
2276 |
4.96e-83 |
SMART |
|
low complexity region
|
2310 |
2317 |
N/A |
INTRINSIC |
|
low complexity region
|
2328 |
2342 |
N/A |
INTRINSIC |
|
Pfam:IR1-M
|
2468 |
2530 |
2.5e-27 |
PFAM |
|
Pfam:IR1-M
|
2544 |
2604 |
7e-30 |
PFAM |
|
low complexity region
|
2673 |
2684 |
N/A |
INTRINSIC |
|
low complexity region
|
2722 |
2732 |
N/A |
INTRINSIC |
|
RanBD
|
2741 |
2869 |
5e-79 |
SMART |
|
Pfam:Pro_isomerase
|
2896 |
3052 |
4.5e-45 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000219332
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000220131
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.6%
- 20x: 93.6%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Heterozygous mice on some backgrounds display reduced ATP levels in the CNS, decreased glucose clearance, decreased weight gain on a high fat diet, and reduced scotopic responses. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 111 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2210408I21Rik |
C |
T |
13: 77,269,920 (GRCm38) |
T741I |
possibly damaging |
Het |
| Acot3 |
A |
T |
12: 84,053,573 (GRCm38) |
Q41L |
probably damaging |
Het |
| Actl7b |
G |
A |
4: 56,740,165 (GRCm38) |
Q398* |
probably null |
Het |
| Adgrb2 |
C |
A |
4: 129,992,624 (GRCm38) |
Q186K |
probably damaging |
Het |
| Akr1a1 |
A |
G |
4: 116,637,974 (GRCm38) |
|
probably null |
Het |
| Ap3s2 |
A |
T |
7: 79,880,490 (GRCm38) |
F192L |
probably damaging |
Het |
| Apobr |
T |
G |
7: 126,584,979 (GRCm38) |
|
probably null |
Het |
| Arhgap5 |
A |
G |
12: 52,519,345 (GRCm38) |
N1033S |
probably damaging |
Het |
| Arid3c |
G |
T |
4: 41,725,947 (GRCm38) |
R219S |
probably damaging |
Het |
| Bves |
C |
T |
10: 45,347,865 (GRCm38) |
T207M |
probably damaging |
Het |
| C330027C09Rik |
A |
C |
16: 49,017,486 (GRCm38) |
I850L |
probably benign |
Het |
| Cacna1d |
T |
C |
14: 30,066,056 (GRCm38) |
K1619R |
probably damaging |
Het |
| Caps2 |
A |
T |
10: 112,190,978 (GRCm38) |
D223V |
possibly damaging |
Het |
| Cd163l1 |
G |
T |
7: 140,220,609 (GRCm38) |
C101F |
probably damaging |
Het |
| Cd3g |
A |
C |
9: 44,974,342 (GRCm38) |
L35R |
probably damaging |
Het |
| Cdh23 |
A |
T |
10: 60,523,536 (GRCm38) |
V261E |
probably benign |
Het |
| Cfap54 |
T |
G |
10: 93,011,020 (GRCm38) |
T1028P |
probably damaging |
Het |
| Ch25h |
C |
A |
19: 34,474,286 (GRCm38) |
V281L |
probably benign |
Het |
| Clu |
G |
T |
14: 65,980,905 (GRCm38) |
V405L |
possibly damaging |
Het |
| Col6a3 |
A |
T |
1: 90,830,213 (GRCm38) |
H6Q |
probably damaging |
Het |
| Cps1 |
G |
A |
1: 67,168,374 (GRCm38) |
|
probably null |
Het |
| Ctr9 |
T |
C |
7: 111,055,663 (GRCm38) |
S1134P |
unknown |
Het |
| Cts7 |
C |
T |
13: 61,352,810 (GRCm38) |
G308S |
probably damaging |
Het |
| Cyp2c39 |
C |
A |
19: 39,566,891 (GRCm38) |
T385K |
probably damaging |
Het |
| Dennd5a |
A |
T |
7: 109,918,712 (GRCm38) |
D596E |
probably benign |
Het |
| Disc1 |
T |
A |
8: 125,124,610 (GRCm38) |
I413K |
probably benign |
Het |
| Dll3 |
C |
T |
7: 28,294,497 (GRCm38) |
G505D |
probably damaging |
Het |
| Dnah3 |
A |
G |
7: 120,078,571 (GRCm38) |
W377R |
probably damaging |
Het |
| Dopey2 |
A |
G |
16: 93,799,926 (GRCm38) |
D1792G |
probably damaging |
Het |
| Dpep3 |
T |
A |
8: 105,973,693 (GRCm38) |
R460S |
probably benign |
Het |
| Ebf4 |
A |
G |
2: 130,358,831 (GRCm38) |
N302S |
probably damaging |
Het |
| Egflam |
T |
C |
15: 7,289,915 (GRCm38) |
E194G |
possibly damaging |
Het |
| Ep400 |
A |
T |
5: 110,693,308 (GRCm38) |
|
probably benign |
Het |
| Ercc6 |
T |
C |
14: 32,526,176 (GRCm38) |
M228T |
probably damaging |
Het |
| Fbxo9 |
T |
C |
9: 78,087,247 (GRCm38) |
T264A |
probably damaging |
Het |
| Fcrl5 |
C |
A |
3: 87,457,414 (GRCm38) |
P486T |
possibly damaging |
Het |
| Fyb |
T |
C |
15: 6,580,479 (GRCm38) |
F178L |
probably damaging |
Het |
| Gaa |
T |
A |
11: 119,280,460 (GRCm38) |
I646N |
probably damaging |
Het |
| Gm11639 |
A |
G |
11: 104,720,688 (GRCm38) |
K452R |
probably benign |
Het |
| Gm13124 |
A |
T |
4: 144,555,406 (GRCm38) |
I272K |
probably damaging |
Het |
| Gm5431 |
A |
T |
11: 48,895,026 (GRCm38) |
V174E |
possibly damaging |
Het |
| Gnpat |
T |
G |
8: 124,886,952 (GRCm38) |
|
probably null |
Het |
| Gucy1a2 |
G |
T |
9: 3,759,622 (GRCm38) |
R476I |
probably benign |
Het |
| Hars |
A |
G |
18: 36,771,103 (GRCm38) |
L241P |
probably damaging |
Het |
| Haus5 |
G |
A |
7: 30,657,903 (GRCm38) |
Q399* |
probably null |
Het |
| Hephl1 |
T |
C |
9: 15,059,246 (GRCm38) |
E984G |
probably damaging |
Het |
| Hmces |
C |
T |
6: 87,921,592 (GRCm38) |
Q132* |
probably null |
Het |
| Hsp90b1 |
G |
T |
10: 86,694,525 (GRCm38) |
T490K |
probably damaging |
Het |
| Idh2 |
T |
G |
7: 80,099,158 (GRCm38) |
E125A |
probably damaging |
Het |
| Ipo13 |
G |
T |
4: 117,904,522 (GRCm38) |
H465Q |
probably benign |
Het |
| Isca2 |
C |
A |
12: 84,773,619 (GRCm38) |
T31K |
probably damaging |
Het |
| Itga9 |
T |
C |
9: 118,698,461 (GRCm38) |
V560A |
probably benign |
Het |
| Jhy |
G |
A |
9: 40,911,157 (GRCm38) |
Q562* |
probably null |
Het |
| Kcnj5 |
A |
G |
9: 32,322,569 (GRCm38) |
I150T |
probably damaging |
Het |
| Kmt2a |
A |
G |
9: 44,841,621 (GRCm38) |
I1419T |
unknown |
Het |
| Lix1 |
T |
C |
17: 17,446,058 (GRCm38) |
F160L |
possibly damaging |
Het |
| Lonrf2 |
G |
A |
1: 38,813,276 (GRCm38) |
P165S |
probably benign |
Het |
| Map4k1 |
A |
T |
7: 28,989,352 (GRCm38) |
Q276L |
possibly damaging |
Het |
| Mmp9 |
G |
A |
2: 164,949,422 (GRCm38) |
G171S |
probably damaging |
Het |
| Mvp |
C |
A |
7: 126,995,735 (GRCm38) |
|
probably null |
Het |
| Mylk3 |
T |
A |
8: 85,364,831 (GRCm38) |
E115V |
probably damaging |
Het |
| Nebl |
T |
A |
2: 17,388,754 (GRCm38) |
T603S |
probably damaging |
Het |
| Nudt15 |
T |
C |
14: 73,523,336 (GRCm38) |
D105G |
probably benign |
Het |
| Olfr1369-ps1 |
G |
A |
13: 21,116,306 (GRCm38) |
V205I |
probably benign |
Het |
| Olfr527 |
A |
C |
7: 140,335,999 (GRCm38) |
T46P |
possibly damaging |
Het |
| Olfr556 |
G |
T |
7: 102,670,162 (GRCm38) |
V81L |
probably damaging |
Het |
| Olfr65 |
T |
A |
7: 103,906,699 (GRCm38) |
W87R |
probably damaging |
Het |
| Olfr685 |
A |
T |
7: 105,180,760 (GRCm38) |
H199Q |
probably damaging |
Het |
| Olfr971 |
A |
G |
9: 39,840,285 (GRCm38) |
M284V |
probably benign |
Het |
| Osbpl9 |
A |
T |
4: 109,066,218 (GRCm38) |
C495S |
probably damaging |
Het |
| Pamr1 |
A |
G |
2: 102,640,852 (GRCm38) |
T507A |
probably benign |
Het |
| Pcdhb9 |
T |
A |
18: 37,403,327 (GRCm38) |
C791* |
probably null |
Het |
| Pcgf6 |
T |
C |
19: 47,050,518 (GRCm38) |
E101G |
probably damaging |
Het |
| Pdgfrl |
A |
T |
8: 40,985,794 (GRCm38) |
I256F |
probably benign |
Het |
| Pdzd7 |
T |
C |
19: 45,045,511 (GRCm38) |
R45G |
possibly damaging |
Het |
| Pecr |
C |
T |
1: 72,277,409 (GRCm38) |
V46I |
possibly damaging |
Het |
| Pgr |
A |
G |
9: 8,922,714 (GRCm38) |
|
probably null |
Het |
| Pik3c2a |
A |
T |
7: 116,417,927 (GRCm38) |
Y198* |
probably null |
Het |
| Pp2d1 |
T |
A |
17: 53,515,310 (GRCm38) |
M243L |
possibly damaging |
Het |
| Ppp1r1a |
T |
A |
15: 103,533,492 (GRCm38) |
I50L |
possibly damaging |
Het |
| Proc |
T |
C |
18: 32,127,406 (GRCm38) |
D222G |
probably benign |
Het |
| Ptprq |
T |
A |
10: 107,534,699 (GRCm38) |
R2044* |
probably null |
Het |
| Reep6 |
T |
A |
10: 80,333,981 (GRCm38) |
F122I |
possibly damaging |
Het |
| Rubcn |
C |
A |
16: 32,843,101 (GRCm38) |
R388S |
probably damaging |
Het |
| Rusc1 |
A |
G |
3: 89,089,293 (GRCm38) |
L62P |
probably damaging |
Het |
| Satb2 |
T |
C |
1: 56,850,289 (GRCm38) |
N423S |
probably damaging |
Het |
| Serpinb9d |
A |
G |
13: 33,200,748 (GRCm38) |
K236R |
probably benign |
Het |
| Slc4a7 |
A |
G |
14: 14,765,709 (GRCm38) |
R680G |
probably benign |
Het |
| Slitrk1 |
T |
A |
14: 108,913,096 (GRCm38) |
Y61F |
probably benign |
Het |
| Son |
A |
G |
16: 91,660,226 (GRCm38) |
|
probably benign |
Het |
| Sparc |
T |
A |
11: 55,395,776 (GRCm38) |
|
probably null |
Het |
| Spon2 |
A |
G |
5: 33,216,385 (GRCm38) |
F194S |
probably damaging |
Het |
| Spta1 |
A |
G |
1: 174,241,042 (GRCm38) |
E2136G |
probably damaging |
Het |
| Stat4 |
T |
C |
1: 52,106,925 (GRCm38) |
S746P |
probably damaging |
Het |
| Stk31 |
T |
A |
6: 49,469,304 (GRCm38) |
S958R |
probably benign |
Het |
| Stom |
T |
A |
2: 35,315,917 (GRCm38) |
I267F |
probably damaging |
Het |
| Stx12 |
A |
T |
4: 132,858,477 (GRCm38) |
D197E |
probably damaging |
Het |
| Taok3 |
A |
T |
5: 117,255,926 (GRCm38) |
N588I |
possibly damaging |
Het |
| Tgs1 |
A |
G |
4: 3,598,658 (GRCm38) |
D657G |
probably damaging |
Het |
| Trim6 |
A |
G |
7: 104,232,837 (GRCm38) |
T432A |
probably damaging |
Het |
| Trim72 |
C |
G |
7: 128,004,585 (GRCm38) |
C34W |
probably damaging |
Het |
| Trpc4ap |
A |
T |
2: 155,657,744 (GRCm38) |
I286N |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,863,561 (GRCm38) |
V321A |
possibly damaging |
Het |
| Utp4 |
T |
A |
8: 106,918,720 (GRCm38) |
I583N |
probably damaging |
Het |
| Wdfy2 |
G |
T |
14: 62,944,097 (GRCm38) |
M225I |
probably benign |
Het |
| Wfdc1 |
A |
G |
8: 119,681,037 (GRCm38) |
T134A |
probably benign |
Het |
| Wnt9b |
A |
G |
11: 103,732,128 (GRCm38) |
S150P |
probably damaging |
Het |
| Zbtb46 |
A |
T |
2: 181,411,684 (GRCm38) |
F412I |
probably damaging |
Het |
| Zc3h15 |
G |
A |
2: 83,661,148 (GRCm38) |
R240H |
probably benign |
Het |
| Zfp11 |
A |
T |
5: 129,656,673 (GRCm38) |
Y575N |
probably benign |
Het |
| Zfp687 |
T |
C |
3: 95,011,889 (GRCm38) |
M191V |
probably benign |
Het |
|
| Other mutations in Ranbp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00229:Ranbp2
|
APN |
10 |
58,477,256 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00336:Ranbp2
|
APN |
10 |
58,451,984 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00486:Ranbp2
|
APN |
10 |
58,477,612 (GRCm38) |
missense |
probably benign |
0.06 |
|
IGL00800:Ranbp2
|
APN |
10 |
58,490,704 (GRCm38) |
missense |
probably benign |
|
|
IGL00834:Ranbp2
|
APN |
10 |
58,453,323 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
IGL00852:Ranbp2
|
APN |
10 |
58,477,901 (GRCm38) |
missense |
probably benign |
|
|
IGL00984:Ranbp2
|
APN |
10 |
58,461,964 (GRCm38) |
nonsense |
probably null |
|
|
IGL01299:Ranbp2
|
APN |
10 |
58,492,817 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01325:Ranbp2
|
APN |
10 |
58,476,298 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL01444:Ranbp2
|
APN |
10 |
58,475,300 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
IGL01545:Ranbp2
|
APN |
10 |
58,478,881 (GRCm38) |
missense |
possibly damaging |
0.48 |
|
IGL01619:Ranbp2
|
APN |
10 |
58,464,078 (GRCm38) |
splice site |
probably null |
|
|
IGL01782:Ranbp2
|
APN |
10 |
58,478,309 (GRCm38) |
missense |
probably damaging |
0.97 |
|
IGL02020:Ranbp2
|
APN |
10 |
58,479,947 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02096:Ranbp2
|
APN |
10 |
58,461,967 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02182:Ranbp2
|
APN |
10 |
58,485,760 (GRCm38) |
nonsense |
probably null |
|
|
IGL02211:Ranbp2
|
APN |
10 |
58,478,242 (GRCm38) |
missense |
probably benign |
|
|
IGL02249:Ranbp2
|
APN |
10 |
58,480,078 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
IGL02268:Ranbp2
|
APN |
10 |
58,493,653 (GRCm38) |
unclassified |
probably benign |
|
|
IGL02421:Ranbp2
|
APN |
10 |
58,480,554 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03080:Ranbp2
|
APN |
10 |
58,476,791 (GRCm38) |
missense |
probably benign |
0.01 |
|
IGL03119:Ranbp2
|
APN |
10 |
58,452,003 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03206:Ranbp2
|
APN |
10 |
58,465,547 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03237:Ranbp2
|
APN |
10 |
58,492,961 (GRCm38) |
missense |
probably damaging |
0.98 |
|
En_passant
|
UTSW |
10 |
58,452,017 (GRCm38) |
missense |
probably damaging |
1.00 |
|
red_river
|
UTSW |
10 |
58,465,667 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02799:Ranbp2
|
UTSW |
10 |
58,480,264 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0058:Ranbp2
|
UTSW |
10 |
58,480,531 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0058:Ranbp2
|
UTSW |
10 |
58,480,531 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R0145:Ranbp2
|
UTSW |
10 |
58,480,046 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0309:Ranbp2
|
UTSW |
10 |
58,479,868 (GRCm38) |
missense |
probably benign |
0.04 |
|
R0375:Ranbp2
|
UTSW |
10 |
58,477,283 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0441:Ranbp2
|
UTSW |
10 |
58,485,768 (GRCm38) |
missense |
probably benign |
0.40 |
|
R0494:Ranbp2
|
UTSW |
10 |
58,467,432 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R0542:Ranbp2
|
UTSW |
10 |
58,478,414 (GRCm38) |
missense |
probably benign |
0.02 |
|
R0565:Ranbp2
|
UTSW |
10 |
58,476,336 (GRCm38) |
missense |
probably benign |
0.41 |
|
R0608:Ranbp2
|
UTSW |
10 |
58,493,898 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0661:Ranbp2
|
UTSW |
10 |
58,478,733 (GRCm38) |
missense |
probably benign |
|
|
R0670:Ranbp2
|
UTSW |
10 |
58,480,698 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0760:Ranbp2
|
UTSW |
10 |
58,476,791 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R0811:Ranbp2
|
UTSW |
10 |
58,465,529 (GRCm38) |
missense |
probably benign |
0.01 |
|
R0812:Ranbp2
|
UTSW |
10 |
58,465,529 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1180:Ranbp2
|
UTSW |
10 |
58,465,463 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1196:Ranbp2
|
UTSW |
10 |
58,477,053 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1216:Ranbp2
|
UTSW |
10 |
58,483,212 (GRCm38) |
splice site |
probably benign |
|
|
R1374:Ranbp2
|
UTSW |
10 |
58,485,893 (GRCm38) |
splice site |
probably benign |
|
|
R1541:Ranbp2
|
UTSW |
10 |
58,483,094 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
R1589:Ranbp2
|
UTSW |
10 |
58,463,986 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1761:Ranbp2
|
UTSW |
10 |
58,485,741 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1831:Ranbp2
|
UTSW |
10 |
58,479,222 (GRCm38) |
nonsense |
probably null |
|
|
R1840:Ranbp2
|
UTSW |
10 |
58,478,766 (GRCm38) |
missense |
probably benign |
0.41 |
|
R1869:Ranbp2
|
UTSW |
10 |
58,492,561 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1871:Ranbp2
|
UTSW |
10 |
58,492,561 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1892:Ranbp2
|
UTSW |
10 |
58,464,099 (GRCm38) |
missense |
probably benign |
0.36 |
|
R2270:Ranbp2
|
UTSW |
10 |
58,455,927 (GRCm38) |
missense |
probably benign |
0.06 |
|
R2363:Ranbp2
|
UTSW |
10 |
58,478,936 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R3844:Ranbp2
|
UTSW |
10 |
58,477,895 (GRCm38) |
missense |
possibly damaging |
0.87 |
|
R3937:Ranbp2
|
UTSW |
10 |
58,476,472 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3938:Ranbp2
|
UTSW |
10 |
58,476,472 (GRCm38) |
missense |
probably benign |
0.00 |
|
R4025:Ranbp2
|
UTSW |
10 |
58,480,556 (GRCm38) |
missense |
probably benign |
0.23 |
|
R4183:Ranbp2
|
UTSW |
10 |
58,465,666 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R4247:Ranbp2
|
UTSW |
10 |
58,478,864 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R4334:Ranbp2
|
UTSW |
10 |
58,463,994 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4656:Ranbp2
|
UTSW |
10 |
58,453,422 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4746:Ranbp2
|
UTSW |
10 |
58,492,670 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4852:Ranbp2
|
UTSW |
10 |
58,477,056 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4863:Ranbp2
|
UTSW |
10 |
58,492,421 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5011:Ranbp2
|
UTSW |
10 |
58,461,895 (GRCm38) |
missense |
probably benign |
0.36 |
|
R5014:Ranbp2
|
UTSW |
10 |
58,464,120 (GRCm38) |
missense |
probably benign |
0.40 |
|
R5145:Ranbp2
|
UTSW |
10 |
58,480,038 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5178:Ranbp2
|
UTSW |
10 |
58,476,785 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5199:Ranbp2
|
UTSW |
10 |
58,464,443 (GRCm38) |
missense |
probably benign |
|
|
R5294:Ranbp2
|
UTSW |
10 |
58,478,668 (GRCm38) |
missense |
probably benign |
0.23 |
|
R5508:Ranbp2
|
UTSW |
10 |
58,480,005 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R5511:Ranbp2
|
UTSW |
10 |
58,493,739 (GRCm38) |
missense |
probably benign |
0.29 |
|
R5575:Ranbp2
|
UTSW |
10 |
58,492,583 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5617:Ranbp2
|
UTSW |
10 |
58,465,667 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5630:Ranbp2
|
UTSW |
10 |
58,479,076 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5733:Ranbp2
|
UTSW |
10 |
58,485,836 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5751:Ranbp2
|
UTSW |
10 |
58,464,264 (GRCm38) |
splice site |
probably null |
|
|
R5767:Ranbp2
|
UTSW |
10 |
58,476,825 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6122:Ranbp2
|
UTSW |
10 |
58,465,529 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6147:Ranbp2
|
UTSW |
10 |
58,479,428 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6286:Ranbp2
|
UTSW |
10 |
58,479,572 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6344:Ranbp2
|
UTSW |
10 |
58,483,886 (GRCm38) |
splice site |
probably null |
|
|
R6452:Ranbp2
|
UTSW |
10 |
58,478,157 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6487:Ranbp2
|
UTSW |
10 |
58,485,741 (GRCm38) |
missense |
probably benign |
0.02 |
|
R6620:Ranbp2
|
UTSW |
10 |
58,455,807 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R6759:Ranbp2
|
UTSW |
10 |
58,457,737 (GRCm38) |
nonsense |
probably null |
|
|
R7010:Ranbp2
|
UTSW |
10 |
58,454,571 (GRCm38) |
critical splice acceptor site |
probably null |
|
|
R7071:Ranbp2
|
UTSW |
10 |
58,492,837 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7083:Ranbp2
|
UTSW |
10 |
58,479,230 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7088:Ranbp2
|
UTSW |
10 |
58,463,906 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7102:Ranbp2
|
UTSW |
10 |
58,463,950 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7194:Ranbp2
|
UTSW |
10 |
58,476,769 (GRCm38) |
missense |
probably benign |
0.05 |
|
R7217:Ranbp2
|
UTSW |
10 |
58,452,017 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7318:Ranbp2
|
UTSW |
10 |
58,483,087 (GRCm38) |
nonsense |
probably null |
|
|
R7341:Ranbp2
|
UTSW |
10 |
58,485,797 (GRCm38) |
missense |
possibly damaging |
0.72 |
|
R7398:Ranbp2
|
UTSW |
10 |
58,467,277 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7424:Ranbp2
|
UTSW |
10 |
58,479,194 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R7727:Ranbp2
|
UTSW |
10 |
58,455,438 (GRCm38) |
missense |
probably benign |
0.09 |
|
R7795:Ranbp2
|
UTSW |
10 |
58,483,907 (GRCm38) |
nonsense |
probably null |
|
|
R7812:Ranbp2
|
UTSW |
10 |
58,467,402 (GRCm38) |
missense |
probably benign |
|
|
R7845:Ranbp2
|
UTSW |
10 |
58,447,022 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7875:Ranbp2
|
UTSW |
10 |
58,478,455 (GRCm38) |
nonsense |
probably null |
|
|
R7934:Ranbp2
|
UTSW |
10 |
58,476,475 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R8022:Ranbp2
|
UTSW |
10 |
58,485,861 (GRCm38) |
missense |
possibly damaging |
0.53 |
|
R8050:Ranbp2
|
UTSW |
10 |
58,479,619 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R8100:Ranbp2
|
UTSW |
10 |
58,490,648 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R8194:Ranbp2
|
UTSW |
10 |
58,455,925 (GRCm38) |
missense |
possibly damaging |
0.84 |
|
R8258:Ranbp2
|
UTSW |
10 |
58,455,933 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8259:Ranbp2
|
UTSW |
10 |
58,455,933 (GRCm38) |
missense |
probably benign |
0.04 |
|
R8461:Ranbp2
|
UTSW |
10 |
58,476,394 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R8722:Ranbp2
|
UTSW |
10 |
58,476,227 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8755:Ranbp2
|
UTSW |
10 |
58,465,147 (GRCm38) |
nonsense |
probably null |
|
|
R8794:Ranbp2
|
UTSW |
10 |
58,492,592 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8879:Ranbp2
|
UTSW |
10 |
58,477,889 (GRCm38) |
missense |
probably benign |
0.10 |
|
R8994:Ranbp2
|
UTSW |
10 |
58,480,069 (GRCm38) |
missense |
possibly damaging |
0.89 |
|
R9023:Ranbp2
|
UTSW |
10 |
58,479,521 (GRCm38) |
nonsense |
probably null |
|
|
R9124:Ranbp2
|
UTSW |
10 |
58,492,897 (GRCm38) |
missense |
probably benign |
0.01 |
|
R9133:Ranbp2
|
UTSW |
10 |
58,477,228 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9145:Ranbp2
|
UTSW |
10 |
58,455,914 (GRCm38) |
missense |
probably benign |
0.03 |
|
R9190:Ranbp2
|
UTSW |
10 |
58,477,295 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9369:Ranbp2
|
UTSW |
10 |
58,480,664 (GRCm38) |
missense |
probably benign |
0.04 |
|
R9394:Ranbp2
|
UTSW |
10 |
58,455,876 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9642:Ranbp2
|
UTSW |
10 |
58,483,085 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9673:Ranbp2
|
UTSW |
10 |
58,465,141 (GRCm38) |
missense |
probably damaging |
1.00 |
|
X0018:Ranbp2
|
UTSW |
10 |
58,478,584 (GRCm38) |
missense |
probably benign |
0.13 |
|
X0022:Ranbp2
|
UTSW |
10 |
58,465,155 (GRCm38) |
missense |
probably benign |
0.33 |
|
Z1088:Ranbp2
|
UTSW |
10 |
58,492,893 (GRCm38) |
missense |
probably benign |
0.35 |
|
Z1088:Ranbp2
|
UTSW |
10 |
58,477,983 (GRCm38) |
frame shift |
probably null |
|
|
Z1088:Ranbp2
|
UTSW |
10 |
58,477,972 (GRCm38) |
frame shift |
probably null |
|
|
Z1176:Ranbp2
|
UTSW |
10 |
58,461,886 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Z1177:Ranbp2
|
UTSW |
10 |
58,493,891 (GRCm38) |
nonsense |
probably null |
|
|
| Predicted Primers |
|
| Posted On |
2014-05-14 |
Incidental Mutation