Incidental Mutation 'R1716:Phldb2'
| ID |
191069 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phldb2
|
| Ensembl Gene |
ENSMUSG00000033149 |
| Gene Name |
pleckstrin homology like domain, family B, member 2 |
| Synonyms |
LL5b, C820004H04Rik, LL5beta |
| MMRRC Submission |
039749-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1716 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
45566606-45773961 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 45595413 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Aspartic acid
at position 883
(G883D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000123284
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036355]
[ENSMUST00000076333]
[ENSMUST00000134802]
|
| AlphaFold |
Q8K1N2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000036355
AA Change: G838D
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000046496
Gene: ENSMUSG00000033149
AA Change: G838D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
coiled coil region
|
1027 |
1097 |
N/A |
INTRINSIC |
|
PH
|
1140 |
1244 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000076333
AA Change: G838D
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000075672
Gene: ENSMUSG00000033149
AA Change: G838D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
267 |
283 |
N/A |
INTRINSIC |
|
low complexity region
|
426 |
447 |
N/A |
INTRINSIC |
|
coiled coil region
|
580 |
692 |
N/A |
INTRINSIC |
|
coiled coil region
|
724 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
901 |
913 |
N/A |
INTRINSIC |
|
coiled coil region
|
1080 |
1150 |
N/A |
INTRINSIC |
|
PH
|
1193 |
1297 |
6.45e-17 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131003
|
| SMART Domains |
Protein: ENSMUSP00000119718
Gene: ENSMUSG00000033149
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
1 |
55 |
N/A |
INTRINSIC |
|
coiled coil region
|
87 |
163 |
N/A |
INTRINSIC |
|
coiled coil region
|
342 |
412 |
N/A |
INTRINSIC |
|
PH
|
456 |
560 |
6.45e-17 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000133111
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000134802
AA Change: G883D
PolyPhen 2
Score 0.006 (Sensitivity: 0.97; Specificity: 0.75)
|
| SMART Domains |
Protein: ENSMUSP00000123284
Gene: ENSMUSG00000033149
AA Change: G883D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
312 |
328 |
N/A |
INTRINSIC |
|
low complexity region
|
471 |
492 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
737 |
N/A |
INTRINSIC |
|
coiled coil region
|
769 |
845 |
N/A |
INTRINSIC |
|
coiled coil region
|
1072 |
1131 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151300
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.5%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acan |
A |
G |
7: 78,731,946 (GRCm39) |
T2A |
unknown |
Het |
| Adgrf3 |
T |
A |
5: 30,402,549 (GRCm39) |
Q493L |
probably benign |
Het |
| Ak6 |
T |
C |
13: 100,792,177 (GRCm39) |
S207P |
probably benign |
Het |
| Ang |
A |
G |
14: 51,338,937 (GRCm39) |
D26G |
probably benign |
Het |
| Ang |
T |
C |
14: 51,338,957 (GRCm39) |
F33L |
probably damaging |
Het |
| Arhgef38 |
T |
A |
3: 132,846,598 (GRCm39) |
Y389F |
probably benign |
Het |
| Arhgef7 |
C |
A |
8: 11,858,713 (GRCm39) |
|
probably null |
Het |
| Bicd2 |
C |
A |
13: 49,531,786 (GRCm39) |
H343N |
probably benign |
Het |
| Casp4 |
G |
A |
9: 5,308,919 (GRCm39) |
|
probably null |
Het |
| Cd22 |
A |
G |
7: 30,577,103 (GRCm39) |
F68S |
probably damaging |
Het |
| Cd46 |
T |
A |
1: 194,760,117 (GRCm39) |
Q245L |
probably benign |
Het |
| Cntnap2 |
A |
T |
6: 47,084,826 (GRCm39) |
R1096* |
probably null |
Het |
| Cntnap3 |
A |
G |
13: 64,909,816 (GRCm39) |
V763A |
probably damaging |
Het |
| Cyp3a11 |
T |
C |
5: 145,805,776 (GRCm39) |
T171A |
probably benign |
Het |
| Defa30 |
A |
G |
8: 21,625,431 (GRCm39) |
Y65C |
probably damaging |
Het |
| Defb18 |
A |
T |
1: 18,306,875 (GRCm39) |
M27K |
probably benign |
Het |
| Dnah17 |
A |
G |
11: 117,923,424 (GRCm39) |
S4071P |
probably benign |
Het |
| Dnah7b |
T |
A |
1: 46,230,943 (GRCm39) |
D1400E |
probably damaging |
Het |
| Dpysl5 |
C |
T |
5: 30,935,338 (GRCm39) |
T147I |
probably benign |
Het |
| Dsg4 |
C |
T |
18: 20,595,518 (GRCm39) |
R574* |
probably null |
Het |
| Entrep2 |
A |
T |
7: 64,426,633 (GRCm39) |
|
probably null |
Het |
| Epm2a |
A |
G |
10: 11,324,580 (GRCm39) |
E223G |
probably benign |
Het |
| Etl4 |
T |
C |
2: 20,748,492 (GRCm39) |
S75P |
probably damaging |
Het |
| Fbxw15 |
T |
A |
9: 109,386,204 (GRCm39) |
M312L |
probably benign |
Het |
| Fcgr4 |
C |
T |
1: 170,847,672 (GRCm39) |
T90I |
probably damaging |
Het |
| Fras1 |
T |
A |
5: 96,700,584 (GRCm39) |
D201E |
probably benign |
Het |
| Gadl1 |
A |
T |
9: 115,835,576 (GRCm39) |
K335* |
probably null |
Het |
| Gcsam |
T |
G |
16: 45,440,356 (GRCm39) |
V133G |
probably damaging |
Het |
| Gml |
G |
T |
15: 74,685,665 (GRCm39) |
L107I |
possibly damaging |
Het |
| Golga2 |
T |
A |
2: 32,192,909 (GRCm39) |
L409Q |
probably damaging |
Het |
| Gtf2a1l |
A |
T |
17: 89,002,008 (GRCm39) |
Q241L |
probably benign |
Het |
| Gtf3c3 |
A |
G |
1: 54,438,419 (GRCm39) |
Y799H |
probably damaging |
Het |
| Guca1b |
T |
G |
17: 47,702,126 (GRCm39) |
|
probably benign |
Het |
| Igdcc4 |
C |
A |
9: 65,034,179 (GRCm39) |
H617Q |
probably damaging |
Het |
| Ip6k1 |
G |
A |
9: 107,918,195 (GRCm39) |
E77K |
possibly damaging |
Het |
| Itga2b |
A |
C |
11: 102,351,603 (GRCm39) |
I574S |
probably benign |
Het |
| Kcnk7 |
A |
T |
19: 5,756,859 (GRCm39) |
I283F |
probably damaging |
Het |
| Kirrel3 |
T |
A |
9: 34,934,843 (GRCm39) |
L450M |
probably damaging |
Het |
| Lmntd1 |
A |
T |
6: 145,365,600 (GRCm39) |
S176R |
probably damaging |
Het |
| Lrrc39 |
C |
T |
3: 116,373,216 (GRCm39) |
T292I |
probably benign |
Het |
| Ltbp1 |
A |
T |
17: 75,622,019 (GRCm39) |
H801L |
probably benign |
Het |
| Macf1 |
T |
A |
4: 123,295,196 (GRCm39) |
Q3318L |
probably damaging |
Het |
| Man1b1 |
T |
A |
2: 25,235,032 (GRCm39) |
N282K |
probably benign |
Het |
| Map2k6 |
A |
T |
11: 110,388,727 (GRCm39) |
E223V |
probably damaging |
Het |
| Marf1 |
C |
A |
16: 13,960,450 (GRCm39) |
R531S |
possibly damaging |
Het |
| Mfge8 |
G |
A |
7: 78,792,191 (GRCm39) |
R245C |
probably damaging |
Het |
| Mogat1 |
T |
G |
1: 78,514,681 (GRCm39) |
N318K |
probably benign |
Het |
| Myh4 |
T |
A |
11: 67,141,135 (GRCm39) |
S732R |
possibly damaging |
Het |
| Myt1l |
T |
A |
12: 29,861,537 (GRCm39) |
D106E |
unknown |
Het |
| Ndc1 |
T |
C |
4: 107,241,992 (GRCm39) |
F302L |
probably damaging |
Het |
| Ndrg4 |
C |
T |
8: 96,438,956 (GRCm39) |
A290V |
probably benign |
Het |
| Nfia |
A |
T |
4: 97,951,365 (GRCm39) |
K397N |
probably damaging |
Het |
| Nlrp4e |
A |
T |
7: 23,020,458 (GRCm39) |
Q315L |
possibly damaging |
Het |
| Oga |
C |
A |
19: 45,740,613 (GRCm39) |
K907N |
probably benign |
Het |
| Or10p22 |
A |
C |
10: 128,826,721 (GRCm39) |
*313C |
probably null |
Het |
| Or1ad8 |
T |
A |
11: 50,898,679 (GRCm39) |
N293K |
probably damaging |
Het |
| Peg3 |
T |
C |
7: 6,710,780 (GRCm39) |
I1481V |
possibly damaging |
Het |
| Pik3c2b |
T |
A |
1: 133,022,564 (GRCm39) |
Y1169N |
probably damaging |
Het |
| Plcl1 |
A |
T |
1: 55,734,997 (GRCm39) |
I113F |
probably damaging |
Het |
| Pomt2 |
T |
C |
12: 87,171,610 (GRCm39) |
I457V |
probably benign |
Het |
| Ppil1 |
T |
C |
17: 29,480,809 (GRCm39) |
N38S |
possibly damaging |
Het |
| Prf1 |
A |
G |
10: 61,136,231 (GRCm39) |
N169S |
probably benign |
Het |
| Prmt8 |
A |
C |
6: 127,703,486 (GRCm39) |
|
probably null |
Het |
| Ptprg |
T |
A |
14: 12,154,360 (GRCm38) |
S694T |
probably benign |
Het |
| Rab12 |
A |
T |
17: 66,807,315 (GRCm39) |
M138K |
possibly damaging |
Het |
| Reln |
T |
C |
5: 22,160,093 (GRCm39) |
T2159A |
probably damaging |
Het |
| Retsat |
A |
T |
6: 72,583,063 (GRCm39) |
Y36F |
probably damaging |
Het |
| Rgs14 |
A |
T |
13: 55,526,696 (GRCm39) |
Q116L |
probably damaging |
Het |
| Rlbp1 |
A |
T |
7: 79,025,684 (GRCm39) |
N252K |
probably damaging |
Het |
| Rtraf |
A |
G |
14: 19,862,242 (GRCm39) |
L215P |
probably damaging |
Het |
| Sec1 |
A |
T |
7: 45,328,789 (GRCm39) |
M86K |
probably benign |
Het |
| Sec24b |
A |
T |
3: 129,834,665 (GRCm39) |
S42T |
possibly damaging |
Het |
| Serpinb9d |
T |
C |
13: 33,380,500 (GRCm39) |
S129P |
probably damaging |
Het |
| Slc35f5 |
T |
G |
1: 125,512,269 (GRCm39) |
D356E |
possibly damaging |
Het |
| Smpd4 |
T |
C |
16: 17,460,365 (GRCm39) |
S694P |
probably damaging |
Het |
| Spag6 |
G |
T |
2: 18,750,420 (GRCm39) |
|
probably null |
Het |
| Spata31d1c |
T |
C |
13: 65,181,030 (GRCm39) |
I43T |
possibly damaging |
Het |
| Ssh1 |
T |
C |
5: 114,090,081 (GRCm39) |
D314G |
possibly damaging |
Het |
| Tnfrsf17 |
G |
A |
16: 11,137,595 (GRCm39) |
D111N |
probably benign |
Het |
| Ttn |
A |
G |
2: 76,553,635 (GRCm39) |
I30994T |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,614,320 (GRCm39) |
F8737L |
probably damaging |
Het |
| Ush1c |
G |
T |
7: 45,845,152 (GRCm39) |
F890L |
probably benign |
Het |
| Usp36 |
C |
T |
11: 118,162,957 (GRCm39) |
|
probably null |
Het |
| Vmn2r115 |
T |
C |
17: 23,566,795 (GRCm39) |
Y436H |
probably benign |
Het |
| Vmn2r94 |
T |
A |
17: 18,477,635 (GRCm39) |
M259L |
probably benign |
Het |
| Wwp1 |
T |
C |
4: 19,659,698 (GRCm39) |
T197A |
probably benign |
Het |
| Zbtb37 |
T |
A |
1: 160,847,814 (GRCm39) |
M398L |
probably benign |
Het |
| Zfp804b |
C |
T |
5: 6,819,673 (GRCm39) |
C1130Y |
probably benign |
Het |
| Zfp9 |
A |
G |
6: 118,441,712 (GRCm39) |
C317R |
probably damaging |
Het |
| Zscan20 |
T |
C |
4: 128,480,334 (GRCm39) |
H719R |
probably damaging |
Het |
|
| Other mutations in Phldb2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00321:Phldb2
|
APN |
16 |
45,592,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00485:Phldb2
|
APN |
16 |
45,577,551 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
IGL00544:Phldb2
|
APN |
16 |
45,645,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00547:Phldb2
|
APN |
16 |
45,645,898 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00835:Phldb2
|
APN |
16 |
45,571,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00987:Phldb2
|
APN |
16 |
45,583,465 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01102:Phldb2
|
APN |
16 |
45,645,423 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01530:Phldb2
|
APN |
16 |
45,623,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Phldb2
|
APN |
16 |
45,594,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01712:Phldb2
|
APN |
16 |
45,571,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01755:Phldb2
|
APN |
16 |
45,645,945 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01823:Phldb2
|
APN |
16 |
45,645,507 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02353:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02360:Phldb2
|
APN |
16 |
45,569,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02716:Phldb2
|
APN |
16 |
45,621,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0139:Phldb2
|
UTSW |
16 |
45,591,029 (GRCm39) |
splice site |
probably benign |
|
|
R0312:Phldb2
|
UTSW |
16 |
45,609,410 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0379:Phldb2
|
UTSW |
16 |
45,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0535:Phldb2
|
UTSW |
16 |
45,577,490 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1387:Phldb2
|
UTSW |
16 |
45,646,357 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R1444:Phldb2
|
UTSW |
16 |
45,577,616 (GRCm39) |
splice site |
probably benign |
|
|
R1487:Phldb2
|
UTSW |
16 |
45,609,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1501:Phldb2
|
UTSW |
16 |
45,598,146 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:Phldb2
|
UTSW |
16 |
45,591,142 (GRCm39) |
splice site |
probably benign |
|
|
R1732:Phldb2
|
UTSW |
16 |
45,577,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1779:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1824:Phldb2
|
UTSW |
16 |
45,646,374 (GRCm39) |
missense |
probably benign |
0.14 |
|
R2001:Phldb2
|
UTSW |
16 |
45,594,558 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R2066:Phldb2
|
UTSW |
16 |
45,591,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Phldb2
|
UTSW |
16 |
45,583,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2448:Phldb2
|
UTSW |
16 |
45,645,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2932:Phldb2
|
UTSW |
16 |
45,569,148 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3076:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3078:Phldb2
|
UTSW |
16 |
45,645,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3779:Phldb2
|
UTSW |
16 |
45,569,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3914:Phldb2
|
UTSW |
16 |
45,577,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4536:Phldb2
|
UTSW |
16 |
45,591,044 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4568:Phldb2
|
UTSW |
16 |
45,598,081 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Phldb2
|
UTSW |
16 |
45,646,237 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4853:Phldb2
|
UTSW |
16 |
45,623,079 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4906:Phldb2
|
UTSW |
16 |
45,571,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4984:Phldb2
|
UTSW |
16 |
45,645,996 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5078:Phldb2
|
UTSW |
16 |
45,598,105 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5137:Phldb2
|
UTSW |
16 |
45,628,621 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5237:Phldb2
|
UTSW |
16 |
45,568,249 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5410:Phldb2
|
UTSW |
16 |
45,645,975 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5825:Phldb2
|
UTSW |
16 |
45,583,460 (GRCm39) |
missense |
probably benign |
0.11 |
|
R5874:Phldb2
|
UTSW |
16 |
45,621,988 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5907:Phldb2
|
UTSW |
16 |
45,645,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6332:Phldb2
|
UTSW |
16 |
45,594,609 (GRCm39) |
missense |
probably benign |
|
|
R6354:Phldb2
|
UTSW |
16 |
45,645,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6355:Phldb2
|
UTSW |
16 |
45,645,701 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6383:Phldb2
|
UTSW |
16 |
45,569,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6463:Phldb2
|
UTSW |
16 |
45,595,356 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6513:Phldb2
|
UTSW |
16 |
45,568,240 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R6593:Phldb2
|
UTSW |
16 |
45,645,790 (GRCm39) |
nonsense |
probably null |
|
|
R6756:Phldb2
|
UTSW |
16 |
45,628,683 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6810:Phldb2
|
UTSW |
16 |
45,569,088 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6897:Phldb2
|
UTSW |
16 |
45,598,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7010:Phldb2
|
UTSW |
16 |
45,571,868 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7142:Phldb2
|
UTSW |
16 |
45,577,539 (GRCm39) |
nonsense |
probably null |
|
|
R7149:Phldb2
|
UTSW |
16 |
45,571,895 (GRCm39) |
nonsense |
probably null |
|
|
R7249:Phldb2
|
UTSW |
16 |
45,621,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7300:Phldb2
|
UTSW |
16 |
45,645,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7328:Phldb2
|
UTSW |
16 |
45,578,572 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7515:Phldb2
|
UTSW |
16 |
45,594,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7840:Phldb2
|
UTSW |
16 |
45,571,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7988:Phldb2
|
UTSW |
16 |
45,645,934 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8159:Phldb2
|
UTSW |
16 |
45,680,747 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8353:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8453:Phldb2
|
UTSW |
16 |
45,645,385 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8969:Phldb2
|
UTSW |
16 |
45,592,496 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9058:Phldb2
|
UTSW |
16 |
45,592,604 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R9106:Phldb2
|
UTSW |
16 |
45,680,757 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9278:Phldb2
|
UTSW |
16 |
45,646,308 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9324:Phldb2
|
UTSW |
16 |
45,595,437 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9563:Phldb2
|
UTSW |
16 |
45,645,247 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9626:Phldb2
|
UTSW |
16 |
45,592,547 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R9712:Phldb2
|
UTSW |
16 |
45,595,340 (GRCm39) |
missense |
probably benign |
0.27 |
|
R9718:Phldb2
|
UTSW |
16 |
45,601,756 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
RF008:Phldb2
|
UTSW |
16 |
45,583,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,773,871 (GRCm39) |
unclassified |
probably benign |
|
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,190 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Phldb2
|
UTSW |
16 |
45,646,189 (GRCm39) |
missense |
probably benign |
0.43 |
|
Z1190:Phldb2
|
UTSW |
16 |
45,645,697 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCAGTCTGGCTCTCTGGAACACAC -3'
(R):5'- TAGCCCATCAGCCATCACTTGC -3'
Sequencing Primer
(F):5'- ATCATTTTCAGTGAACAGTGGG -3'
(R):5'- GACATTCTTCAAGATTGAGCACCG -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation