Incidental Mutation 'R1691:Phrf1'
| ID |
191790 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Phrf1
|
| Ensembl Gene |
ENSMUSG00000038611 |
| Gene Name |
PHD and ring finger domains 1 |
| Synonyms |
|
| MMRRC Submission |
039724-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1691 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
140808697-140842663 bp(+) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
C to A
at 140841787 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Stop codon
at position 715
(Y715*)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000026571]
[ENSMUST00000097952]
[ENSMUST00000106023]
[ENSMUST00000106027]
[ENSMUST00000122143]
[ENSMUST00000209899]
[ENSMUST00000132540]
[ENSMUST00000155123]
|
| AlphaFold |
A6H619 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000026571
|
| SMART Domains |
Protein: ENSMUSP00000026571
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
240 |
420 |
1.38e-63 |
SMART |
|
low complexity region
|
425 |
442 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000097952
|
| SMART Domains |
Protein: ENSMUSP00000095565
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
209 |
389 |
1.38e-63 |
SMART |
|
low complexity region
|
394 |
411 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106023
|
| SMART Domains |
Protein: ENSMUSP00000101644
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
5 |
127 |
1.13e-54 |
SMART |
|
IRF-3
|
208 |
388 |
1.38e-63 |
SMART |
|
low complexity region
|
393 |
410 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000106027
AA Change: Y1625*
|
| SMART Domains |
Protein: ENSMUSP00000101648
Gene: ENSMUSG00000038611
AA Change: Y1625*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
39 |
70 |
N/A |
INTRINSIC |
|
RING
|
109 |
149 |
3.78e-5 |
SMART |
|
C1
|
173 |
229 |
7.05e-2 |
SMART |
|
PHD
|
187 |
233 |
1.77e-14 |
SMART |
|
RING
|
188 |
232 |
3.17e0 |
SMART |
|
low complexity region
|
332 |
369 |
N/A |
INTRINSIC |
|
low complexity region
|
491 |
505 |
N/A |
INTRINSIC |
|
low complexity region
|
507 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
717 |
728 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
857 |
N/A |
INTRINSIC |
|
low complexity region
|
891 |
902 |
N/A |
INTRINSIC |
|
low complexity region
|
944 |
955 |
N/A |
INTRINSIC |
|
low complexity region
|
965 |
976 |
N/A |
INTRINSIC |
|
low complexity region
|
999 |
1020 |
N/A |
INTRINSIC |
|
low complexity region
|
1027 |
1043 |
N/A |
INTRINSIC |
|
low complexity region
|
1051 |
1090 |
N/A |
INTRINSIC |
|
low complexity region
|
1094 |
1151 |
N/A |
INTRINSIC |
|
low complexity region
|
1160 |
1173 |
N/A |
INTRINSIC |
|
low complexity region
|
1217 |
1241 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1261 |
N/A |
INTRINSIC |
|
low complexity region
|
1288 |
1306 |
N/A |
INTRINSIC |
|
low complexity region
|
1308 |
1319 |
N/A |
INTRINSIC |
|
low complexity region
|
1359 |
1376 |
N/A |
INTRINSIC |
|
low complexity region
|
1426 |
1441 |
N/A |
INTRINSIC |
|
low complexity region
|
1575 |
1592 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
1593 |
1636 |
4e-14 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000122143
AA Change: Y1466*
|
| SMART Domains |
Protein: ENSMUSP00000113195
Gene: ENSMUSG00000038611
AA Change: Y1466*
| Domain | Start | End | E-Value | Type |
|---|
|
C1
|
14 |
70 |
7.05e-2 |
SMART |
|
PHD
|
28 |
74 |
1.77e-14 |
SMART |
|
low complexity region
|
173 |
210 |
N/A |
INTRINSIC |
|
low complexity region
|
332 |
346 |
N/A |
INTRINSIC |
|
low complexity region
|
348 |
363 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
672 |
698 |
N/A |
INTRINSIC |
|
low complexity region
|
732 |
743 |
N/A |
INTRINSIC |
|
low complexity region
|
785 |
796 |
N/A |
INTRINSIC |
|
low complexity region
|
806 |
817 |
N/A |
INTRINSIC |
|
low complexity region
|
840 |
861 |
N/A |
INTRINSIC |
|
low complexity region
|
868 |
884 |
N/A |
INTRINSIC |
|
low complexity region
|
892 |
931 |
N/A |
INTRINSIC |
|
low complexity region
|
935 |
992 |
N/A |
INTRINSIC |
|
low complexity region
|
1001 |
1014 |
N/A |
INTRINSIC |
|
low complexity region
|
1058 |
1082 |
N/A |
INTRINSIC |
|
low complexity region
|
1086 |
1102 |
N/A |
INTRINSIC |
|
low complexity region
|
1129 |
1147 |
N/A |
INTRINSIC |
|
low complexity region
|
1149 |
1160 |
N/A |
INTRINSIC |
|
low complexity region
|
1200 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1267 |
1282 |
N/A |
INTRINSIC |
|
low complexity region
|
1416 |
1433 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
1434 |
1477 |
4e-14 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000122868
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000123525
|
| SMART Domains |
Protein: ENSMUSP00000121026
Gene: ENSMUSG00000025498
| Domain | Start | End | E-Value | Type |
|---|
|
IRF
|
1 |
69 |
6.35e-3 |
SMART |
|
IRF-3
|
77 |
251 |
2.62e-55 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000130687
AA Change: Y273*
|
| SMART Domains |
Protein: ENSMUSP00000123351
Gene: ENSMUSG00000038611
AA Change: Y273*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
33 |
50 |
N/A |
INTRINSIC |
|
low complexity region
|
100 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
224 |
241 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
242 |
285 |
5e-15 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000142572
AA Change: Y715*
|
| SMART Domains |
Protein: ENSMUSP00000117393
Gene: ENSMUSG00000038611
AA Change: Y715*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
31 |
N/A |
INTRINSIC |
|
low complexity region
|
41 |
52 |
N/A |
INTRINSIC |
|
low complexity region
|
75 |
96 |
N/A |
INTRINSIC |
|
low complexity region
|
103 |
119 |
N/A |
INTRINSIC |
|
low complexity region
|
127 |
166 |
N/A |
INTRINSIC |
|
low complexity region
|
170 |
227 |
N/A |
INTRINSIC |
|
low complexity region
|
236 |
249 |
N/A |
INTRINSIC |
|
low complexity region
|
293 |
317 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
337 |
N/A |
INTRINSIC |
|
low complexity region
|
364 |
382 |
N/A |
INTRINSIC |
|
low complexity region
|
384 |
395 |
N/A |
INTRINSIC |
|
low complexity region
|
435 |
452 |
N/A |
INTRINSIC |
|
low complexity region
|
666 |
683 |
N/A |
INTRINSIC |
|
Blast:IG_like
|
684 |
727 |
3e-14 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000209899
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000132540
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000155744
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000156938
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000144250
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148414
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127161
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000127223
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146373
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000131399
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000210506
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000155123
|
| SMART Domains |
Protein: ENSMUSP00000120759
Gene: ENSMUSG00000038611
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
24 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
39 |
70 |
N/A |
INTRINSIC |
|
RING
|
109 |
149 |
3.78e-5 |
SMART |
|
Blast:C1
|
165 |
209 |
2e-17 |
BLAST |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamtsl3 |
T |
C |
7: 82,148,814 (GRCm39) |
S283P |
probably damaging |
Het |
| Adck2 |
T |
A |
6: 39,551,902 (GRCm39) |
L223* |
probably null |
Het |
| Ank |
T |
C |
15: 27,591,030 (GRCm39) |
W390R |
probably damaging |
Het |
| Ano5 |
T |
C |
7: 51,240,327 (GRCm39) |
Y752H |
probably damaging |
Het |
| Apcs |
T |
A |
1: 172,722,160 (GRCm39) |
D62V |
probably damaging |
Het |
| Atad5 |
A |
G |
11: 79,986,358 (GRCm39) |
T482A |
probably benign |
Het |
| Atp7b |
A |
G |
8: 22,501,039 (GRCm39) |
Y955H |
possibly damaging |
Het |
| Ccdc13 |
A |
T |
9: 121,654,134 (GRCm39) |
|
probably null |
Het |
| Ccdc157 |
G |
A |
11: 4,099,030 (GRCm39) |
P159S |
probably benign |
Het |
| Cdhr3 |
C |
T |
12: 33,132,246 (GRCm39) |
V126M |
probably damaging |
Het |
| Cdr1 |
T |
C |
X: 60,227,780 (GRCm39) |
D462G |
possibly damaging |
Het |
| Cisd1 |
A |
G |
10: 71,180,559 (GRCm39) |
V9A |
probably benign |
Het |
| Col19a1 |
T |
C |
1: 24,576,022 (GRCm39) |
R107G |
unknown |
Het |
| Col1a2 |
C |
A |
6: 4,536,038 (GRCm39) |
H972Q |
unknown |
Het |
| Col3a1 |
T |
A |
1: 45,387,776 (GRCm39) |
|
probably benign |
Het |
| Dbnl |
A |
G |
11: 5,747,174 (GRCm39) |
S235G |
probably null |
Het |
| Dock4 |
T |
A |
12: 40,775,754 (GRCm39) |
S566T |
probably benign |
Het |
| Efcab6 |
T |
C |
15: 83,817,407 (GRCm39) |
D722G |
probably benign |
Het |
| Esyt1 |
T |
C |
10: 128,361,403 (GRCm39) |
Q97R |
probably benign |
Het |
| Fat2 |
G |
A |
11: 55,202,678 (GRCm39) |
T132I |
probably damaging |
Het |
| Fgd2 |
C |
T |
17: 29,597,918 (GRCm39) |
Q618* |
probably null |
Het |
| Flnc |
T |
A |
6: 29,441,213 (GRCm39) |
V389E |
probably benign |
Het |
| Garnl3 |
A |
T |
2: 32,887,675 (GRCm39) |
Y778* |
probably null |
Het |
| Gpaa1 |
A |
T |
15: 76,216,416 (GRCm39) |
Y45F |
probably damaging |
Het |
| Grid1 |
A |
T |
14: 35,174,286 (GRCm39) |
I643F |
probably damaging |
Het |
| Gsdmc2 |
T |
C |
15: 63,705,314 (GRCm39) |
D133G |
probably damaging |
Het |
| Hp |
T |
C |
8: 110,302,204 (GRCm39) |
D248G |
probably benign |
Het |
| Hsh2d |
G |
A |
8: 72,954,304 (GRCm39) |
D229N |
probably benign |
Het |
| Ifna13 |
T |
C |
4: 88,562,291 (GRCm39) |
D111G |
probably benign |
Het |
| Il9r |
T |
A |
11: 32,141,829 (GRCm39) |
Q309L |
possibly damaging |
Het |
| Insyn2a |
C |
T |
7: 134,520,015 (GRCm39) |
A172T |
probably damaging |
Het |
| Ints1 |
A |
T |
5: 139,754,687 (GRCm39) |
D617E |
probably damaging |
Het |
| Kcnj12 |
A |
T |
11: 60,961,103 (GRCm39) |
N467I |
possibly damaging |
Het |
| Kmt2e |
T |
A |
5: 23,669,847 (GRCm39) |
D111E |
probably damaging |
Het |
| Lama4 |
A |
G |
10: 38,956,559 (GRCm39) |
K1161E |
probably benign |
Het |
| Lamc1 |
C |
T |
1: 153,122,995 (GRCm39) |
D732N |
probably benign |
Het |
| Larp1 |
A |
G |
11: 57,938,874 (GRCm39) |
T517A |
probably benign |
Het |
| Lrp12 |
A |
G |
15: 39,735,661 (GRCm39) |
I757T |
probably damaging |
Het |
| Max |
T |
C |
12: 77,000,046 (GRCm39) |
D23G |
possibly damaging |
Het |
| Nars1 |
A |
T |
18: 64,649,485 (GRCm39) |
|
probably null |
Het |
| Nipsnap3a |
G |
A |
4: 52,994,185 (GRCm39) |
D91N |
probably null |
Het |
| Nphp3 |
A |
G |
9: 103,880,010 (GRCm39) |
T11A |
probably benign |
Het |
| Nr2c2 |
C |
A |
6: 92,133,673 (GRCm39) |
T226K |
probably damaging |
Het |
| Nrxn1 |
A |
G |
17: 90,469,717 (GRCm39) |
I1288T |
probably damaging |
Het |
| Nt5c1b |
C |
T |
12: 10,425,537 (GRCm39) |
T360I |
possibly damaging |
Het |
| Ofcc1 |
C |
T |
13: 40,362,305 (GRCm39) |
G206R |
probably benign |
Het |
| Or10a3b |
A |
G |
7: 108,444,348 (GRCm39) |
Y290H |
possibly damaging |
Het |
| Or13a21 |
A |
T |
7: 139,998,855 (GRCm39) |
L277Q |
probably damaging |
Het |
| Or4e1 |
A |
T |
14: 52,701,288 (GRCm39) |
H59Q |
possibly damaging |
Het |
| Or4k37 |
G |
A |
2: 111,159,198 (GRCm39) |
V145I |
probably benign |
Het |
| Or6d14 |
A |
G |
6: 116,533,538 (GRCm39) |
T51A |
probably benign |
Het |
| Or9i1b |
C |
T |
19: 13,896,783 (GRCm39) |
T133I |
probably benign |
Het |
| Pcsk1 |
A |
G |
13: 75,280,344 (GRCm39) |
D723G |
possibly damaging |
Het |
| Pigm |
T |
C |
1: 172,204,354 (GRCm39) |
V30A |
probably benign |
Het |
| Pkd1l2 |
A |
T |
8: 117,783,158 (GRCm39) |
F721I |
possibly damaging |
Het |
| Pla2g15 |
A |
G |
8: 106,881,581 (GRCm39) |
D70G |
possibly damaging |
Het |
| Prl7d1 |
A |
T |
13: 27,893,365 (GRCm39) |
I182N |
probably damaging |
Het |
| Prss23 |
T |
C |
7: 89,159,922 (GRCm39) |
K49R |
probably benign |
Het |
| Rps6 |
A |
T |
4: 86,775,046 (GRCm39) |
D19E |
probably benign |
Het |
| Slco6d1 |
A |
T |
1: 98,435,292 (GRCm39) |
H669L |
probably benign |
Het |
| Svil |
G |
T |
18: 5,056,336 (GRCm39) |
C490F |
probably benign |
Het |
| Tom1 |
T |
C |
8: 75,778,227 (GRCm39) |
I103T |
probably damaging |
Het |
| Trim10 |
T |
A |
17: 37,187,791 (GRCm39) |
Y336N |
probably damaging |
Het |
| Trim43c |
G |
T |
9: 88,722,752 (GRCm39) |
V133F |
probably damaging |
Het |
| Tvp23a |
A |
G |
16: 10,246,551 (GRCm39) |
L78P |
possibly damaging |
Het |
| Ugt2b38 |
T |
A |
5: 87,571,991 (GRCm39) |
I14L |
probably benign |
Het |
| Unc5a |
A |
C |
13: 55,150,737 (GRCm39) |
M520L |
probably damaging |
Het |
| Vmn1r174 |
T |
A |
7: 23,453,337 (GRCm39) |
M1K |
probably null |
Het |
| Vmn2r58 |
C |
T |
7: 41,486,913 (GRCm39) |
G661R |
possibly damaging |
Het |
| Vps41 |
A |
C |
13: 19,025,413 (GRCm39) |
D471A |
probably damaging |
Het |
| Zbtb14 |
C |
A |
17: 69,695,497 (GRCm39) |
F398L |
probably damaging |
Het |
| Zfp462 |
T |
A |
4: 55,013,489 (GRCm39) |
F1818L |
possibly damaging |
Het |
| Zp3 |
G |
A |
5: 136,009,135 (GRCm39) |
E50K |
possibly damaging |
Het |
|
| Other mutations in Phrf1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00551:Phrf1
|
APN |
7 |
140,838,790 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01391:Phrf1
|
APN |
7 |
140,842,394 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01472:Phrf1
|
APN |
7 |
140,836,403 (GRCm39) |
splice site |
probably benign |
|
|
IGL01633:Phrf1
|
APN |
7 |
140,840,413 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL01808:Phrf1
|
APN |
7 |
140,840,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02004:Phrf1
|
APN |
7 |
140,840,246 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02138:Phrf1
|
APN |
7 |
140,839,196 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02678:Phrf1
|
APN |
7 |
140,840,195 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03077:Phrf1
|
APN |
7 |
140,834,881 (GRCm39) |
nonsense |
probably null |
|
|
PIT4466001:Phrf1
|
UTSW |
7 |
140,838,725 (GRCm39) |
missense |
unknown |
|
|
R0036:Phrf1
|
UTSW |
7 |
140,841,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0036:Phrf1
|
UTSW |
7 |
140,841,693 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Phrf1
|
UTSW |
7 |
140,823,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0358:Phrf1
|
UTSW |
7 |
140,838,217 (GRCm39) |
unclassified |
probably benign |
|
|
R0445:Phrf1
|
UTSW |
7 |
140,827,244 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R0535:Phrf1
|
UTSW |
7 |
140,839,978 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0561:Phrf1
|
UTSW |
7 |
140,834,876 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0940:Phrf1
|
UTSW |
7 |
140,834,768 (GRCm39) |
splice site |
probably benign |
|
|
R1499:Phrf1
|
UTSW |
7 |
140,836,564 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1511:Phrf1
|
UTSW |
7 |
140,839,714 (GRCm39) |
unclassified |
probably benign |
|
|
R1651:Phrf1
|
UTSW |
7 |
140,817,434 (GRCm39) |
missense |
probably benign |
|
|
R1778:Phrf1
|
UTSW |
7 |
140,812,369 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1851:Phrf1
|
UTSW |
7 |
140,820,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2239:Phrf1
|
UTSW |
7 |
140,817,605 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2857:Phrf1
|
UTSW |
7 |
140,839,593 (GRCm39) |
unclassified |
probably benign |
|
|
R3796:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3797:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3798:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R3799:Phrf1
|
UTSW |
7 |
140,839,831 (GRCm39) |
nonsense |
probably null |
|
|
R4080:Phrf1
|
UTSW |
7 |
140,839,633 (GRCm39) |
unclassified |
probably benign |
|
|
R4081:Phrf1
|
UTSW |
7 |
140,838,970 (GRCm39) |
unclassified |
probably benign |
|
|
R4557:Phrf1
|
UTSW |
7 |
140,838,842 (GRCm39) |
unclassified |
probably benign |
|
|
R5217:Phrf1
|
UTSW |
7 |
140,840,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5218:Phrf1
|
UTSW |
7 |
140,841,214 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5276:Phrf1
|
UTSW |
7 |
140,839,196 (GRCm39) |
unclassified |
probably benign |
|
|
R5442:Phrf1
|
UTSW |
7 |
140,820,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5501:Phrf1
|
UTSW |
7 |
140,839,834 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5695:Phrf1
|
UTSW |
7 |
140,838,378 (GRCm39) |
unclassified |
probably benign |
|
|
R5837:Phrf1
|
UTSW |
7 |
140,839,974 (GRCm39) |
missense |
probably benign |
0.34 |
|
R5907:Phrf1
|
UTSW |
7 |
140,840,453 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5996:Phrf1
|
UTSW |
7 |
140,839,015 (GRCm39) |
unclassified |
probably benign |
|
|
R6024:Phrf1
|
UTSW |
7 |
140,838,898 (GRCm39) |
unclassified |
probably benign |
|
|
R6244:Phrf1
|
UTSW |
7 |
140,817,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6512:Phrf1
|
UTSW |
7 |
140,840,309 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7016:Phrf1
|
UTSW |
7 |
140,817,476 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7311:Phrf1
|
UTSW |
7 |
140,820,846 (GRCm39) |
missense |
unknown |
|
|
R7409:Phrf1
|
UTSW |
7 |
140,839,205 (GRCm39) |
missense |
unknown |
|
|
R7517:Phrf1
|
UTSW |
7 |
140,836,523 (GRCm39) |
missense |
unknown |
|
|
R7560:Phrf1
|
UTSW |
7 |
140,811,138 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7699:Phrf1
|
UTSW |
7 |
140,834,842 (GRCm39) |
missense |
unknown |
|
|
R7700:Phrf1
|
UTSW |
7 |
140,834,842 (GRCm39) |
missense |
unknown |
|
|
R7867:Phrf1
|
UTSW |
7 |
140,836,524 (GRCm39) |
missense |
unknown |
|
|
R7895:Phrf1
|
UTSW |
7 |
140,839,288 (GRCm39) |
missense |
unknown |
|
|
R8179:Phrf1
|
UTSW |
7 |
140,836,493 (GRCm39) |
missense |
unknown |
|
|
R8705:Phrf1
|
UTSW |
7 |
140,838,651 (GRCm39) |
missense |
unknown |
|
|
R8708:Phrf1
|
UTSW |
7 |
140,812,446 (GRCm39) |
missense |
unknown |
|
|
R8748:Phrf1
|
UTSW |
7 |
140,838,148 (GRCm39) |
missense |
unknown |
|
|
R8768:Phrf1
|
UTSW |
7 |
140,838,651 (GRCm39) |
missense |
unknown |
|
|
R8789:Phrf1
|
UTSW |
7 |
140,836,581 (GRCm39) |
missense |
unknown |
|
|
R8859:Phrf1
|
UTSW |
7 |
140,836,516 (GRCm39) |
missense |
unknown |
|
|
R8991:Phrf1
|
UTSW |
7 |
140,823,671 (GRCm39) |
missense |
unknown |
|
|
R9086:Phrf1
|
UTSW |
7 |
140,839,412 (GRCm39) |
missense |
unknown |
|
|
R9158:Phrf1
|
UTSW |
7 |
140,836,466 (GRCm39) |
missense |
unknown |
|
|
R9287:Phrf1
|
UTSW |
7 |
140,840,055 (GRCm39) |
missense |
probably benign |
0.35 |
|
R9561:Phrf1
|
UTSW |
7 |
140,834,815 (GRCm39) |
missense |
unknown |
|
|
X0027:Phrf1
|
UTSW |
7 |
140,836,481 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Phrf1
|
UTSW |
7 |
140,838,731 (GRCm39) |
missense |
unknown |
|
|
Z1176:Phrf1
|
UTSW |
7 |
140,823,796 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AACTCCTGGCTTCTCGCCAATG -3'
(R):5'- TGTAACCACACTTCACAGAGCTGC -3'
Sequencing Primer
(F):5'- GAAGCTGCACATGCAAGAAC -3'
(R):5'- CACAGAGCTGCTGAGGTTTATC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation