Mutagenetix > Incidental Mutation

Incidental Mutation 'R1694:Nlrp1b'

192043

Institutional Source

Beutler Lab

Gene Symbol

Nlrp1b

Ensembl Gene

ENSMUSG00000070390

Gene Name

NLR family, pyrin domain containing 1B

Synonyms

Nalp1b

MMRRC Submission

039727-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.063) question?

Stock #

R1694 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

71043928-71121559 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to G at 71107681 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000104156 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000094046] [ENSMUST00000094046] [ENSMUST00000108516] [ENSMUST00000108516] [ENSMUST00000136493]

AlphaFold

A1Z198

Predicted Effect

probably null
Transcript: ENSMUST00000094046

SMART Domains

Protein: ENSMUSP00000091588
Gene: ENSMUSG00000070390

Domain	Start	End	E-Value	Type
Pfam:NACHT	131	300	6.7e-43	PFAM
LRR	627	654	2.24e0	SMART
LRR	656	683	8.82e0	SMART
LRR	684	711	3.49e-5	SMART
Pfam:FIIND	812	1064	8.2e-104	PFAM
Pfam:CARD	1083	1166	3.1e-22	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000094046

SMART Domains

Protein: ENSMUSP00000091588
Gene: ENSMUSG00000070390

Domain	Start	End	E-Value	Type
Pfam:NACHT	131	300	6.7e-43	PFAM
LRR	627	654	2.24e0	SMART
LRR	656	683	8.82e0	SMART
LRR	684	711	3.49e-5	SMART
Pfam:FIIND	812	1064	8.2e-104	PFAM
Pfam:CARD	1083	1166	3.1e-22	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000108516

SMART Domains

Protein: ENSMUSP00000104156
Gene: ENSMUSG00000070390

Domain	Start	End	E-Value	Type
Pfam:NACHT	131	300	2.2e-42	PFAM
LRR	627	654	2.24e0	SMART
LRR	656	683	8.82e0	SMART
LRR	684	711	3.49e-5	SMART
Pfam:FIIND	811	1065	3.9e-136	PFAM
Pfam:CARD	1083	1166	1.1e-21	PFAM

Predicted Effect

probably null
Transcript: ENSMUST00000108516

SMART Domains

Protein: ENSMUSP00000104156
Gene: ENSMUSG00000070390

Domain	Start	End	E-Value	Type
Pfam:NACHT	131	300	2.2e-42	PFAM
LRR	627	654	2.24e0	SMART
LRR	656	683	8.82e0	SMART
LRR	684	711	3.49e-5	SMART
Pfam:FIIND	811	1065	3.9e-136	PFAM
Pfam:CARD	1083	1166	1.1e-21	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000136493

SMART Domains

Protein: ENSMUSP00000121155
Gene: ENSMUSG00000070390

Domain	Start	End	E-Value	Type
Pfam:NACHT	131	300	8.9e-43	PFAM
PDB:4IM6\|A	610	662	6e-10	PDB
Blast:LRR	627	654	3e-11	BLAST

Coding Region Coverage

1x: 99.1%
3x: 98.3%
10x: 96.3%
20x: 92.5%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit protection from anthrax lethal toxin-induced lung injury and pyroptosis of macrophages. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 98 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921513I03Rik	T	C	10: 120,614,533 (GRCm39)		probably benign	Het
4930447C04Rik	C	T	12: 72,931,992 (GRCm39)		probably null	Het
Abca16	A	G	7: 120,119,307 (GRCm39)	H1017R	probably damaging	Het
Actl11	A	G	9: 107,807,207 (GRCm39)	Y510C	probably damaging	Het
Agbl2	A	G	2: 90,631,664 (GRCm39)	T341A	probably damaging	Het
Agbl5	A	G	5: 31,050,726 (GRCm39)	Y458C	probably damaging	Het
Akap5	C	T	12: 76,376,698 (GRCm39)	S710L	probably damaging	Het
Akr1c21	A	G	13: 4,625,177 (GRCm39)	E36G	probably damaging	Het
Arhgap44	A	G	11: 64,944,023 (GRCm39)	S163P	probably damaging	Het
Armc1	A	G	3: 19,189,050 (GRCm39)	V205A	possibly damaging	Het
Asph	A	G	4: 9,610,869 (GRCm39)	L102P	probably damaging	Het
Brca1	T	C	11: 101,422,925 (GRCm39)	E74G	probably damaging	Het
Brms1l	A	G	12: 55,888,385 (GRCm39)	R58G	probably damaging	Het
C1qbp	G	T	11: 70,869,073 (GRCm39)		probably null	Het
Calcrl	A	T	2: 84,169,631 (GRCm39)	L350H	probably damaging	Het
Casr	A	T	16: 36,315,953 (GRCm39)	F706I	probably damaging	Het
Ceacam10	T	A	7: 24,480,491 (GRCm39)	N87K	probably benign	Het
Cfap206	G	T	4: 34,719,058 (GRCm39)	T316K	probably damaging	Het
Col4a3	A	T	1: 82,668,384 (GRCm39)		probably null	Het
Comtd1	A	G	14: 21,897,398 (GRCm39)	V183A	probably damaging	Het
Crygs	A	T	16: 22,625,425 (GRCm39)		probably null	Het
Dact1	C	A	12: 71,359,551 (GRCm39)	T139K	probably damaging	Het
Dlx6	T	C	6: 6,867,173 (GRCm39)	W259R	probably damaging	Het
Dnah9	G	T	11: 65,845,650 (GRCm39)	S627*	probably null	Het
Dnajc11	T	A	4: 152,063,730 (GRCm39)	V442D	probably damaging	Het
Dnajc21	A	T	15: 10,451,649 (GRCm39)	S393T	probably benign	Het
Dpysl3	C	A	18: 43,461,439 (GRCm39)	C584F	possibly damaging	Het
Efcab14	A	G	4: 115,603,736 (GRCm39)	K138R	possibly damaging	Het
Ephb3	A	G	16: 21,040,495 (GRCm39)	E577G	probably damaging	Het
Exoc3	C	T	13: 74,338,184 (GRCm39)		probably null	Het
Fam171a1	A	G	2: 3,226,660 (GRCm39)	S473G	probably benign	Het
Fbxl2	A	T	9: 113,832,239 (GRCm39)	F58L	probably damaging	Het
Fmo6	T	C	1: 162,750,241 (GRCm39)	M272V	probably benign	Het
Gm10000	T	C	12: 104,442,859 (GRCm39)		probably benign	Het
Grik1	T	A	16: 87,746,956 (GRCm39)	D442V	probably damaging	Het
Hectd1	A	G	12: 51,791,375 (GRCm39)	Y2588H	probably damaging	Het
Insrr	A	C	3: 87,711,369 (GRCm39)	T430P	probably benign	Het
Lats1	T	C	10: 7,577,709 (GRCm39)	S278P	probably benign	Het
Lrch4	A	G	5: 137,636,723 (GRCm39)	T463A	probably benign	Het
Ltbp1	A	G	17: 75,532,280 (GRCm39)	Q118R	possibly damaging	Het
Lyst	T	G	13: 13,835,746 (GRCm39)	F1809L	probably damaging	Het
Mad2l1bp	A	G	17: 46,463,770 (GRCm39)	Y85H	possibly damaging	Het
Magoh	G	T	4: 107,740,362 (GRCm39)	R82L	probably benign	Het
Mdfic2	A	C	6: 98,215,100 (GRCm39)	S174R	probably damaging	Het
Mlh1	A	G	9: 111,057,543 (GRCm39)	V756A	probably damaging	Het
Mlh3	T	C	12: 85,313,915 (GRCm39)	E757G	probably damaging	Het
Mycbp2	T	C	14: 103,464,947 (GRCm39)	T1339A	probably damaging	Het
Myh7b	A	T	2: 155,455,113 (GRCm39)	E46V	probably damaging	Het
Naalad2	T	A	9: 18,238,683 (GRCm39)	R677S	probably damaging	Het
Nadsyn1	G	A	7: 143,361,749 (GRCm39)	T324I	probably benign	Het
Neo1	A	T	9: 58,787,886 (GRCm39)	L1389Q	probably damaging	Het
Nup210	A	C	6: 91,039,785 (GRCm39)	I690S	probably benign	Het
Or55b3	A	T	7: 102,126,547 (GRCm39)	S177T	probably benign	Het
Or5an11	T	A	19: 12,246,281 (GRCm39)	I229N	probably damaging	Het
Or9r7	T	A	10: 129,962,123 (GRCm39)	I268F	possibly damaging	Het
Otud7a	C	A	7: 63,383,458 (GRCm39)	H316N	probably damaging	Het
Pcdh15	T	C	10: 74,429,995 (GRCm39)	S1241P	probably damaging	Het
Pclo	A	G	5: 14,570,977 (GRCm39)	K121E	probably damaging	Het
Pcmtd1	A	T	1: 7,217,872 (GRCm39)	I107L	probably benign	Het
Pde6c	A	G	19: 38,168,673 (GRCm39)	I755V	probably damaging	Het
Pes1	CGGAGGAGGAGGAGGAGGAGGAGG	CGGAGGAGGAGGAGGAGGAGG	11: 3,927,719 (GRCm39)		probably benign	Het
Pi4ka	A	T	16: 17,113,240 (GRCm39)	I1532N	probably damaging	Het
Pla2r1	A	G	2: 60,271,428 (GRCm39)		probably null	Het
Plb1	A	G	5: 32,474,621 (GRCm39)	N661S	probably null	Het
Plekhd1	A	G	12: 80,769,095 (GRCm39)	K452E	possibly damaging	Het
Prr12	C	A	7: 44,678,003 (GRCm39)	V2003F	unknown	Het
Ptger1	G	A	8: 84,395,107 (GRCm39)	G195R	probably benign	Het
Ptpn4	T	C	1: 119,711,240 (GRCm39)	Q67R	probably damaging	Het
Rgsl1	C	T	1: 153,680,422 (GRCm39)	R760H	probably damaging	Het
Rock1	A	G	18: 10,136,094 (GRCm39)		probably null	Het
Rtn1	T	C	12: 72,270,298 (GRCm39)	Y71C	probably damaging	Het
Rtp4	T	C	16: 23,431,870 (GRCm39)	*62Q	probably null	Het
Scaf4	GGCTGCTGCTGCTGCTGCTGCTGCTG	GGCTGCTGCTGCTGCTGCTGCTG	16: 90,026,745 (GRCm39)		probably benign	Het
Scimp	G	T	11: 70,684,618 (GRCm39)	P78H	probably damaging	Het
Scn8a	C	A	15: 100,853,409 (GRCm39)	S132*	probably null	Het
Set	A	G	2: 29,959,436 (GRCm39)	I124M	probably damaging	Het
Sf3b1	C	G	1: 55,058,554 (GRCm39)	E12Q	possibly damaging	Het
Sgce	A	G	6: 4,689,709 (GRCm39)	S375P	probably damaging	Het
Slc4a1ap	G	C	5: 31,701,098 (GRCm39)	E600Q	probably damaging	Het
Slit1	A	G	19: 41,626,031 (GRCm39)	V577A	possibly damaging	Het
Sqstm1	A	G	11: 50,098,307 (GRCm39)	V153A	probably benign	Het
Src	A	G	2: 157,311,675 (GRCm39)	M468V	possibly damaging	Het
Srrm3	A	G	5: 135,902,079 (GRCm39)		probably benign	Het
Stk11ip	C	T	1: 75,504,030 (GRCm39)	R257W	probably damaging	Het
Tfrc	T	A	16: 32,433,443 (GRCm39)	D32E	probably damaging	Het
Tor1aip2	A	T	1: 155,941,031 (GRCm39)	I446L	probably benign	Het
Trmt11	T	C	10: 30,411,221 (GRCm39)	H424R	probably benign	Het
Urb1	A	G	16: 90,563,928 (GRCm39)	Y1612H	probably benign	Het
Vcan	A	T	13: 89,836,602 (GRCm39)	S2981T	probably damaging	Het
Vdac1	G	C	11: 52,265,190 (GRCm39)	G21A	probably damaging	Het
Vmn2r76	A	G	7: 85,879,356 (GRCm39)	S315P	probably benign	Het
Xpo1	A	G	11: 23,231,399 (GRCm39)	T328A	probably benign	Het
Xrcc5	C	T	1: 72,358,255 (GRCm39)	L197F	possibly damaging	Het
Zfhx2	G	C	14: 55,311,401 (GRCm39)	S431C	possibly damaging	Het
Zfp410	C	T	12: 84,372,494 (GRCm39)	P54S	probably benign	Het
Zfp560	C	A	9: 20,259,282 (GRCm39)	G527*	probably null	Het
Zfp775	A	G	6: 48,596,389 (GRCm39)	T88A	possibly damaging	Het
Zfp780b	T	A	7: 27,663,808 (GRCm39)	H249L	possibly damaging	Het

Other mutations in Nlrp1b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00161:Nlrp1b	APN	11	71,072,007 (GRCm39)	intron	probably benign
IGL00571:Nlrp1b	APN	11	71,054,799 (GRCm39)	missense	probably null	0.48
IGL01358:Nlrp1b	APN	11	71,072,682 (GRCm39)	missense	possibly damaging	0.91
IGL01937:Nlrp1b	APN	11	71,072,233 (GRCm39)	missense	probably damaging	0.98
IGL01945:Nlrp1b	APN	11	71,072,233 (GRCm39)	missense	probably damaging	0.98
IGL02375:Nlrp1b	APN	11	71,052,506 (GRCm39)	missense	probably damaging	1.00
IGL02552:Nlrp1b	APN	11	71,063,057 (GRCm39)	missense	possibly damaging	0.96
IGL02552:Nlrp1b	APN	11	71,072,878 (GRCm39)	missense	possibly damaging	0.57
IGL02588:Nlrp1b	APN	11	71,073,105 (GRCm39)	nonsense	probably null
IGL02833:Nlrp1b	APN	11	71,051,998 (GRCm39)	missense	probably benign
IGL02955:Nlrp1b	APN	11	71,060,637 (GRCm39)	missense	possibly damaging	0.73
IGL03002:Nlrp1b	APN	11	71,059,685 (GRCm39)	missense	probably benign	0.00
IGL03033:Nlrp1b	APN	11	71,052,665 (GRCm39)	missense	probably benign	0.22
IGL03122:Nlrp1b	APN	11	71,072,659 (GRCm39)	missense	probably benign	0.00
IGL03131:Nlrp1b	APN	11	71,052,741 (GRCm39)	missense	possibly damaging	0.82
androcles	UTSW	11	71,062,901 (GRCm39)	nonsense	probably null
Fangled	UTSW	11	71,062,997 (GRCm39)	missense	possibly damaging	0.94
glitz	UTSW	11	71,072,376 (GRCm39)	missense	possibly damaging	0.89
honeydew	UTSW	11	71,108,710 (GRCm39)	missense	possibly damaging	0.93
Mush	UTSW	11	71,046,905 (GRCm39)	missense	probably damaging	1.00
Thorn	UTSW	11	71,047,126 (GRCm39)	splice site	probably benign
R0001:Nlrp1b	UTSW	11	71,052,585 (GRCm39)	missense	probably damaging	1.00
R0022:Nlrp1b	UTSW	11	71,052,755 (GRCm39)	missense	possibly damaging	0.61
R0022:Nlrp1b	UTSW	11	71,052,755 (GRCm39)	missense	possibly damaging	0.61
R0038:Nlrp1b	UTSW	11	71,062,997 (GRCm39)	missense	possibly damaging	0.94
R0038:Nlrp1b	UTSW	11	71,062,997 (GRCm39)	missense	possibly damaging	0.94
R0164:Nlrp1b	UTSW	11	71,054,925 (GRCm39)	missense	probably damaging	1.00
R0164:Nlrp1b	UTSW	11	71,054,925 (GRCm39)	missense	probably damaging	1.00
R0271:Nlrp1b	UTSW	11	71,052,591 (GRCm39)	missense	possibly damaging	0.51
R0464:Nlrp1b	UTSW	11	71,109,070 (GRCm39)	missense	probably damaging	1.00
R0504:Nlrp1b	UTSW	11	71,073,241 (GRCm39)	missense	probably damaging	0.99
R0605:Nlrp1b	UTSW	11	71,047,005 (GRCm39)	missense	possibly damaging	0.88
R0863:Nlrp1b	UTSW	11	71,072,173 (GRCm39)	missense	probably benign	0.00
R1075:Nlrp1b	UTSW	11	71,072,512 (GRCm39)	missense	probably benign	0.35
R1221:Nlrp1b	UTSW	11	71,072,290 (GRCm39)	missense	probably benign	0.07
R1501:Nlrp1b	UTSW	11	71,046,885 (GRCm39)	missense	probably damaging	1.00
R1654:Nlrp1b	UTSW	11	71,072,124 (GRCm39)	missense	probably damaging	0.99
R1671:Nlrp1b	UTSW	11	71,092,085 (GRCm39)	missense	probably benign	0.45
R1676:Nlrp1b	UTSW	11	71,073,637 (GRCm39)	missense	probably benign	0.13
R1709:Nlrp1b	UTSW	11	71,092,099 (GRCm39)	missense	probably benign	0.11
R1770:Nlrp1b	UTSW	11	71,050,979 (GRCm39)	missense	probably benign	0.22
R1775:Nlrp1b	UTSW	11	71,052,647 (GRCm39)	missense	probably damaging	1.00
R1851:Nlrp1b	UTSW	11	71,073,442 (GRCm39)	missense	possibly damaging	0.96
R1932:Nlrp1b	UTSW	11	71,072,964 (GRCm39)	missense	probably damaging	0.96
R2063:Nlrp1b	UTSW	11	71,051,912 (GRCm39)	missense	probably benign	0.09
R2189:Nlrp1b	UTSW	11	71,060,621 (GRCm39)	missense	probably damaging	1.00
R2223:Nlrp1b	UTSW	11	71,046,815 (GRCm39)	splice site	probably benign
R2284:Nlrp1b	UTSW	11	71,047,110 (GRCm39)	missense	probably benign	0.00
R2434:Nlrp1b	UTSW	11	71,047,552 (GRCm39)	splice site	probably null
R3079:Nlrp1b	UTSW	11	71,108,794 (GRCm39)	missense	probably benign	0.27
R3775:Nlrp1b	UTSW	11	71,047,126 (GRCm39)	splice site	probably benign
R3980:Nlrp1b	UTSW	11	71,072,437 (GRCm39)	missense	possibly damaging	0.56
R4016:Nlrp1b	UTSW	11	71,063,911 (GRCm39)	missense	probably damaging	1.00
R4085:Nlrp1b	UTSW	11	71,052,588 (GRCm39)	missense	probably damaging	0.98
R4542:Nlrp1b	UTSW	11	71,119,151 (GRCm39)	missense	probably damaging	1.00
R4623:Nlrp1b	UTSW	11	71,052,669 (GRCm39)	missense	probably benign	0.00
R4726:Nlrp1b	UTSW	11	71,072,232 (GRCm39)	missense	probably benign	0.10
R4764:Nlrp1b	UTSW	11	71,073,489 (GRCm39)	missense	probably damaging	1.00
R4885:Nlrp1b	UTSW	11	71,108,710 (GRCm39)	missense	possibly damaging	0.93
R4910:Nlrp1b	UTSW	11	71,108,103 (GRCm39)	missense	probably benign	0.09
R4997:Nlrp1b	UTSW	11	71,109,160 (GRCm39)	missense	probably damaging	1.00
R5046:Nlrp1b	UTSW	11	71,050,898 (GRCm39)	missense	possibly damaging	0.95
R5126:Nlrp1b	UTSW	11	71,072,359 (GRCm39)	missense	possibly damaging	0.67
R5369:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
R5388:Nlrp1b	UTSW	11	71,062,967 (GRCm39)	missense	probably damaging	1.00
R5445:Nlrp1b	UTSW	11	71,108,701 (GRCm39)	missense	probably benign	0.21
R5546:Nlrp1b	UTSW	11	71,108,102 (GRCm39)	missense	probably benign	0.04
R5567:Nlrp1b	UTSW	11	71,072,229 (GRCm39)	missense	probably benign
R5826:Nlrp1b	UTSW	11	71,072,022 (GRCm39)	missense	probably benign	0.17
R5955:Nlrp1b	UTSW	11	71,108,691 (GRCm39)	missense	probably damaging	1.00
R5995:Nlrp1b	UTSW	11	71,072,572 (GRCm39)	missense	probably damaging	1.00
R6059:Nlrp1b	UTSW	11	71,107,836 (GRCm39)	missense	possibly damaging	0.53
R6170:Nlrp1b	UTSW	11	71,046,905 (GRCm39)	missense	probably damaging	1.00
R6191:Nlrp1b	UTSW	11	71,109,283 (GRCm39)	nonsense	probably null
R6250:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign	0.11
R6312:Nlrp1b	UTSW	11	71,119,223 (GRCm39)	missense	probably benign	0.38
R6352:Nlrp1b	UTSW	11	71,072,527 (GRCm39)	missense	probably damaging	0.99
R6807:Nlrp1b	UTSW	11	71,108,530 (GRCm39)	missense	probably damaging	1.00
R6854:Nlrp1b	UTSW	11	71,119,259 (GRCm39)	missense	possibly damaging	0.93
R6908:Nlrp1b	UTSW	11	71,108,122 (GRCm39)	missense	probably benign
R6938:Nlrp1b	UTSW	11	71,109,042 (GRCm39)	missense	probably damaging	1.00
R7098:Nlrp1b	UTSW	11	71,109,100 (GRCm39)	missense	possibly damaging	0.89
R7142:Nlrp1b	UTSW	11	71,062,901 (GRCm39)	nonsense	probably null
R7149:Nlrp1b	UTSW	11	71,072,482 (GRCm39)	nonsense	probably null
R7349:Nlrp1b	UTSW	11	71,072,943 (GRCm39)	missense	probably benign	0.36
R7354:Nlrp1b	UTSW	11	71,072,376 (GRCm39)	missense	possibly damaging	0.89
R7750:Nlrp1b	UTSW	11	71,059,665 (GRCm39)	missense	probably benign	0.11
R7913:Nlrp1b	UTSW	11	71,108,537 (GRCm39)	missense	possibly damaging	0.93
R8031:Nlrp1b	UTSW	11	71,107,747 (GRCm39)	missense	probably benign	0.15
R8087:Nlrp1b	UTSW	11	71,062,897 (GRCm39)	missense	probably benign	0.04
R8164:Nlrp1b	UTSW	11	71,119,243 (GRCm39)	missense	possibly damaging	0.78
R8378:Nlrp1b	UTSW	11	71,052,545 (GRCm39)	missense	possibly damaging	0.95
R8405:Nlrp1b	UTSW	11	71,073,356 (GRCm39)	missense	possibly damaging	0.66
R8441:Nlrp1b	UTSW	11	71,073,204 (GRCm39)	missense	probably damaging	1.00
R8792:Nlrp1b	UTSW	11	71,050,919 (GRCm39)	missense	probably benign	0.02
R8898:Nlrp1b	UTSW	11	71,073,288 (GRCm39)	missense	probably damaging	1.00
R8953:Nlrp1b	UTSW	11	71,052,632 (GRCm39)	missense	probably damaging	0.96
R8963:Nlrp1b	UTSW	11	71,108,658 (GRCm39)	missense	probably damaging	1.00
R9145:Nlrp1b	UTSW	11	71,109,193 (GRCm39)	missense	probably benign
R9184:Nlrp1b	UTSW	11	71,072,067 (GRCm39)	missense	probably damaging	1.00
R9286:Nlrp1b	UTSW	11	71,060,573 (GRCm39)	missense	probably benign
R9322:Nlrp1b	UTSW	11	71,108,118 (GRCm39)	missense	probably benign	0.12
R9453:Nlrp1b	UTSW	11	71,072,913 (GRCm39)	missense	probably damaging	0.98
R9533:Nlrp1b	UTSW	11	71,109,095 (GRCm39)	missense	probably benign	0.12
R9659:Nlrp1b	UTSW	11	71,073,132 (GRCm39)	missense	possibly damaging	0.77
Z1176:Nlrp1b	UTSW	11	71,073,096 (GRCm39)	missense	probably damaging	1.00
Z1177:Nlrp1b	UTSW	11	71,108,050 (GRCm39)	missense	probably benign	0.03
Z1177:Nlrp1b	UTSW	11	71,072,125 (GRCm39)	nonsense	probably null
Z1186:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1186:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1186:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,073,135 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1186:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1186:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1186:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1187:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1187:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1187:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1187:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1187:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1188:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1188:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,135 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1188:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1188:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1189:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1189:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1189:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,073,135 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1189:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1189:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1189:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1190:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1190:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1190:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,135 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1190:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1191:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1191:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,073,135 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,072,539 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1191:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1191:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1191:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1192:Nlrp1b	UTSW	11	71,073,396 (GRCm39)	missense	probably benign	0.02
Z1192:Nlrp1b	UTSW	11	71,073,378 (GRCm39)	missense	probably benign
Z1192:Nlrp1b	UTSW	11	71,073,370 (GRCm39)	missense	probably benign	0.00
Z1192:Nlrp1b	UTSW	11	71,073,280 (GRCm39)	missense	probably benign	0.00
Z1192:Nlrp1b	UTSW	11	71,073,266 (GRCm39)	missense	probably benign
Z1192:Nlrp1b	UTSW	11	71,073,148 (GRCm39)	missense	probably benign
Z1192:Nlrp1b	UTSW	11	71,072,625 (GRCm39)	missense	probably benign
Z1192:Nlrp1b	UTSW	11	71,072,534 (GRCm39)	missense	probably benign	0.02
Z1192:Nlrp1b	UTSW	11	71,073,503 (GRCm39)	missense	probably benign

Predicted Primers

Posted On

2014-05-14