Incidental Mutation 'R1695:Kirrel1'
| ID |
192107 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
039728-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R1695 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 86996458 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Isoleucine
at position 380
(M380I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000041732
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000107618
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000159976
AA Change: M380I
PolyPhen 2
Score 0.461 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: M380I
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0922 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 83 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam1b |
T |
A |
5: 121,638,970 (GRCm39) |
T692S |
probably benign |
Het |
| Adgrf3 |
T |
A |
5: 30,408,553 (GRCm39) |
N75I |
probably benign |
Het |
| Adgrg5 |
A |
G |
8: 95,664,373 (GRCm39) |
M328V |
probably damaging |
Het |
| Adk |
A |
G |
14: 21,431,668 (GRCm39) |
D286G |
probably benign |
Het |
| Ankrd28 |
T |
A |
14: 31,429,201 (GRCm39) |
D917V |
probably damaging |
Het |
| Appl2 |
C |
T |
10: 83,457,446 (GRCm39) |
D141N |
probably damaging |
Het |
| Arfgef2 |
T |
C |
2: 166,706,632 (GRCm39) |
V952A |
probably damaging |
Het |
| Arpc2 |
T |
A |
1: 74,287,391 (GRCm39) |
H70Q |
probably damaging |
Het |
| Bpifa5 |
T |
C |
2: 154,009,580 (GRCm39) |
L261P |
probably damaging |
Het |
| Brca1 |
G |
T |
11: 101,415,281 (GRCm39) |
T951K |
probably damaging |
Het |
| Ccdc73 |
A |
T |
2: 104,822,450 (GRCm39) |
S800C |
probably damaging |
Het |
| Cdh15 |
C |
G |
8: 123,588,755 (GRCm39) |
D276E |
probably benign |
Het |
| Cfap119 |
A |
G |
7: 127,186,745 (GRCm39) |
|
probably null |
Het |
| Cfap418 |
T |
A |
4: 10,874,644 (GRCm39) |
D10E |
probably damaging |
Het |
| Cfh |
T |
C |
1: 140,030,575 (GRCm39) |
I551V |
probably damaging |
Het |
| Chd7 |
T |
A |
4: 8,833,960 (GRCm39) |
L1238Q |
probably damaging |
Het |
| Chd9 |
T |
G |
8: 91,728,410 (GRCm39) |
F1275L |
probably damaging |
Het |
| Chrnb3 |
A |
G |
8: 27,883,728 (GRCm39) |
Y155C |
probably damaging |
Het |
| Cltc |
C |
A |
11: 86,591,886 (GRCm39) |
|
probably null |
Het |
| Ctsll3 |
T |
A |
13: 60,948,791 (GRCm39) |
N55Y |
probably damaging |
Het |
| Cysltr2 |
T |
C |
14: 73,267,321 (GRCm39) |
M130V |
probably benign |
Het |
| Daglb |
T |
C |
5: 143,480,361 (GRCm39) |
M455T |
probably benign |
Het |
| Dbn1 |
A |
G |
13: 55,624,521 (GRCm39) |
S343P |
probably benign |
Het |
| Dnah2 |
T |
A |
11: 69,405,517 (GRCm39) |
D665V |
possibly damaging |
Het |
| Dusp6 |
T |
A |
10: 99,099,555 (GRCm39) |
M1K |
probably null |
Het |
| Eif3m |
T |
C |
2: 104,847,298 (GRCm39) |
E12G |
probably damaging |
Het |
| Epha2 |
T |
C |
4: 141,033,828 (GRCm39) |
V29A |
possibly damaging |
Het |
| Farp2 |
T |
A |
1: 93,488,047 (GRCm39) |
N91K |
probably damaging |
Het |
| Ferd3l |
C |
A |
12: 33,978,971 (GRCm39) |
S161R |
probably benign |
Het |
| Fgd2 |
A |
T |
17: 29,587,219 (GRCm39) |
D315V |
possibly damaging |
Het |
| Fhip2a |
T |
C |
19: 57,367,603 (GRCm39) |
W337R |
probably damaging |
Het |
| Fstl4 |
T |
A |
11: 53,056,705 (GRCm39) |
|
probably null |
Het |
| Grm5 |
A |
G |
7: 87,685,311 (GRCm39) |
D476G |
possibly damaging |
Het |
| Gtf3c3 |
C |
T |
1: 54,456,937 (GRCm39) |
A488T |
probably damaging |
Het |
| Hdlbp |
A |
G |
1: 93,364,922 (GRCm39) |
L115P |
probably damaging |
Het |
| Hk2 |
T |
A |
6: 82,721,932 (GRCm39) |
N136Y |
probably damaging |
Het |
| Hs2st1 |
G |
T |
3: 144,140,415 (GRCm39) |
A302E |
probably benign |
Het |
| Htr7 |
T |
C |
19: 35,947,136 (GRCm39) |
N293D |
probably benign |
Het |
| Ikbkb |
T |
A |
8: 23,163,496 (GRCm39) |
E271D |
probably benign |
Het |
| Il5ra |
A |
T |
6: 106,715,335 (GRCm39) |
Y166* |
probably null |
Het |
| Il9r |
T |
A |
11: 32,143,227 (GRCm39) |
H244L |
probably benign |
Het |
| Itih4 |
T |
C |
14: 30,613,456 (GRCm39) |
|
probably null |
Het |
| Large1 |
A |
T |
8: 73,544,710 (GRCm39) |
D689E |
probably damaging |
Het |
| Limk2 |
A |
G |
11: 3,303,275 (GRCm39) |
|
probably null |
Het |
| Med15 |
A |
G |
16: 17,540,644 (GRCm39) |
F34S |
probably damaging |
Het |
| Mprip |
C |
T |
11: 59,643,357 (GRCm39) |
T505I |
probably damaging |
Het |
| Mtor |
T |
A |
4: 148,623,364 (GRCm39) |
N2071K |
probably benign |
Het |
| Muc16 |
A |
G |
9: 18,408,729 (GRCm39) |
L2522P |
probably damaging |
Het |
| Myd88 |
A |
T |
9: 119,166,908 (GRCm39) |
|
probably null |
Het |
| Myo7a |
A |
C |
7: 97,741,703 (GRCm39) |
F484V |
possibly damaging |
Het |
| Nme1 |
A |
C |
11: 93,851,593 (GRCm39) |
L81R |
probably benign |
Het |
| Ntn4 |
T |
A |
10: 93,569,464 (GRCm39) |
|
probably null |
Het |
| Or2y13 |
T |
C |
11: 49,415,162 (GRCm39) |
V204A |
probably benign |
Het |
| Or4p19 |
T |
C |
2: 88,242,444 (GRCm39) |
D186G |
probably damaging |
Het |
| Or51l4 |
A |
T |
7: 103,404,131 (GRCm39) |
Y220* |
probably null |
Het |
| Otogl |
T |
G |
10: 107,649,878 (GRCm39) |
N1159T |
probably damaging |
Het |
| Pabpc6 |
G |
A |
17: 9,887,003 (GRCm39) |
T516I |
probably benign |
Het |
| Pcdh1 |
C |
T |
18: 38,335,921 (GRCm39) |
R238H |
probably damaging |
Het |
| Pex5l |
T |
A |
3: 33,008,531 (GRCm39) |
N151I |
probably benign |
Het |
| Plekha7 |
T |
C |
7: 115,727,920 (GRCm39) |
N980S |
probably damaging |
Het |
| Reg4 |
C |
T |
3: 98,143,677 (GRCm39) |
T157I |
probably benign |
Het |
| Rev3l |
A |
T |
10: 39,700,612 (GRCm39) |
E1703V |
probably damaging |
Het |
| Rev3l |
G |
T |
10: 39,700,611 (GRCm39) |
E1703* |
probably null |
Het |
| Rsf1 |
GCG |
GCGACG |
7: 97,229,114 (GRCm39) |
|
probably benign |
Het |
| Saal1 |
T |
C |
7: 46,342,340 (GRCm39) |
K368E |
probably damaging |
Het |
| Scn9a |
C |
T |
2: 66,335,220 (GRCm39) |
W1245* |
probably null |
Het |
| Slc38a11 |
T |
A |
2: 65,147,315 (GRCm39) |
L387F |
probably damaging |
Het |
| Sned1 |
G |
A |
1: 93,209,376 (GRCm39) |
V830M |
possibly damaging |
Het |
| Sptb |
C |
A |
12: 76,667,641 (GRCm39) |
V819L |
probably benign |
Het |
| Sptbn1 |
T |
C |
11: 30,086,124 (GRCm39) |
T1195A |
probably benign |
Het |
| Ssna1 |
C |
A |
2: 25,162,024 (GRCm39) |
V57F |
possibly damaging |
Het |
| Stk32a |
G |
T |
18: 43,446,485 (GRCm39) |
E312* |
probably null |
Het |
| Synpo |
A |
G |
18: 60,736,459 (GRCm39) |
F496L |
probably benign |
Het |
| Syt15 |
C |
T |
14: 33,944,858 (GRCm39) |
T135M |
probably benign |
Het |
| Tm9sf4 |
A |
G |
2: 153,032,832 (GRCm39) |
E246G |
probably benign |
Het |
| Trim44 |
T |
C |
2: 102,187,830 (GRCm39) |
M308V |
possibly damaging |
Het |
| Unc119b |
T |
A |
5: 115,272,885 (GRCm39) |
K29* |
probably null |
Het |
| Vim |
T |
A |
2: 13,584,921 (GRCm39) |
D367E |
probably benign |
Het |
| Virma |
T |
A |
4: 11,494,814 (GRCm39) |
N38K |
probably damaging |
Het |
| Vmn1r228 |
A |
T |
17: 20,996,560 (GRCm39) |
D319E |
possibly damaging |
Het |
| Vmn2r32 |
T |
A |
7: 7,466,991 (GRCm39) |
I846F |
probably benign |
Het |
| Vps13b |
T |
C |
15: 35,576,667 (GRCm39) |
V1025A |
probably benign |
Het |
| Vps13c |
G |
T |
9: 67,879,357 (GRCm39) |
E566* |
probably null |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5304:Kirrel1
|
UTSW |
3 |
86,996,902 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GTATGGCTGACTGCAAGTACCCTC -3'
(R):5'- GGGACGAAAACTCCACTAACCTGG -3'
Sequencing Primer
(F):5'- GACTGCAAGTACCCTCTTTCC -3'
(R):5'- AGCTGATGATTCTCAGGCAC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation