Incidental Mutation 'R1699:Dab1'
| ID |
192493 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dab1
|
| Ensembl Gene |
ENSMUSG00000028519 |
| Gene Name |
disabled 1 |
| Synonyms |
C630028C02Rik |
| MMRRC Submission |
039732-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.859)
|
| Stock # |
R1699 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
4 |
| Chromosomal Location |
103476556-104602041 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 104588948 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Alanine to Valine
at position 524
(A524V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000102443
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000106830]
[ENSMUST00000146078]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000106830
AA Change: A524V
PolyPhen 2
Score 0.289 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000102443
Gene: ENSMUSG00000028519
AA Change: A524V
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
254 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
470 |
487 |
N/A |
INTRINSIC |
|
low complexity region
|
490 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000146078
|
| SMART Domains |
Protein: ENSMUSP00000125033
Gene: ENSMUSG00000028519
| Domain | Start | End | E-Value | Type |
|---|
|
PTB
|
37 |
171 |
3.51e-36 |
SMART |
|
low complexity region
|
235 |
242 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.2232 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The laminar organization of multiple neuronal types in the cerebral cortex is required for normal cognitive function. In mice, the disabled-1 gene plays a central role in brain development, directing the migration of cortical neurons past previously formed neurons to reach their proper layer. This gene is similar to disabled-1, and the protein encoded by this gene is thought to be a signal transducer that interacts with protein kinase pathways to regulate neuronal positioning in the developing brain. [provided by RefSeq, Jan 2017]
PHENOTYPE: Homozygous null display unstable gait and whole-body tremor with a hypoplastic cerebellum devoid of folia, a probable consequence of defective neuronal migration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca2 |
A |
G |
2: 25,337,363 (GRCm39) |
E2406G |
possibly damaging |
Het |
| Adam6b |
T |
A |
12: 113,454,205 (GRCm39) |
F341I |
probably benign |
Het |
| Adam8 |
A |
T |
7: 139,563,224 (GRCm39) |
N767K |
possibly damaging |
Het |
| Aig1 |
T |
C |
10: 13,744,366 (GRCm39) |
D46G |
possibly damaging |
Het |
| Alms1 |
A |
G |
6: 85,599,862 (GRCm39) |
I2032V |
possibly damaging |
Het |
| Ankrd16 |
A |
G |
2: 11,789,204 (GRCm39) |
I264V |
probably benign |
Het |
| Areg |
T |
G |
5: 91,291,357 (GRCm39) |
V100G |
probably damaging |
Het |
| Bcan |
A |
G |
3: 87,896,543 (GRCm39) |
Y718H |
probably damaging |
Het |
| Brsk2 |
T |
A |
7: 141,539,200 (GRCm39) |
I188N |
probably damaging |
Het |
| Cdt1 |
T |
C |
8: 123,296,722 (GRCm39) |
Y203H |
probably damaging |
Het |
| Cfap119 |
A |
T |
7: 127,186,028 (GRCm39) |
|
probably null |
Het |
| Chil3 |
A |
C |
3: 106,067,682 (GRCm39) |
|
probably null |
Het |
| Ciao2b |
A |
G |
8: 105,366,718 (GRCm39) |
V132A |
probably damaging |
Het |
| Cimip2c |
A |
G |
5: 30,641,210 (GRCm39) |
|
probably null |
Het |
| Cth |
A |
G |
3: 157,613,073 (GRCm39) |
L253P |
probably damaging |
Het |
| Cyp11b1 |
A |
G |
15: 74,712,666 (GRCm39) |
F132L |
possibly damaging |
Het |
| Dnah11 |
A |
G |
12: 118,154,603 (GRCm39) |
S226P |
probably damaging |
Het |
| Egfr |
A |
T |
11: 16,809,019 (GRCm39) |
Q71L |
probably benign |
Het |
| Eml6 |
T |
A |
11: 29,696,282 (GRCm39) |
K1940* |
probably null |
Het |
| Epn2 |
T |
A |
11: 61,414,014 (GRCm39) |
K391* |
probably null |
Het |
| Erich1 |
A |
T |
8: 14,140,259 (GRCm39) |
S2T |
possibly damaging |
Het |
| Evi5 |
A |
C |
5: 107,966,786 (GRCm39) |
L245R |
probably damaging |
Het |
| Evpl |
T |
C |
11: 116,118,414 (GRCm39) |
Y731C |
probably damaging |
Het |
| Exoc3l |
G |
A |
8: 106,021,645 (GRCm39) |
H128Y |
probably benign |
Het |
| Extl1 |
G |
A |
4: 134,091,894 (GRCm39) |
Q320* |
probably null |
Het |
| Fam91a1 |
T |
A |
15: 58,304,797 (GRCm39) |
S416T |
probably benign |
Het |
| Fat3 |
A |
T |
9: 15,849,694 (GRCm39) |
S3903T |
probably damaging |
Het |
| Fer1l4 |
A |
G |
2: 155,871,605 (GRCm39) |
F1392L |
probably benign |
Het |
| Fstl4 |
T |
C |
11: 53,059,005 (GRCm39) |
I488T |
possibly damaging |
Het |
| Gak |
A |
T |
5: 108,752,243 (GRCm39) |
Y338* |
probably null |
Het |
| Garin4 |
T |
A |
1: 190,896,018 (GRCm39) |
E208D |
probably benign |
Het |
| Glp2r |
T |
C |
11: 67,648,367 (GRCm39) |
T112A |
probably benign |
Het |
| Glrb |
G |
A |
3: 80,769,081 (GRCm39) |
T180I |
probably damaging |
Het |
| Gm10118 |
C |
T |
10: 63,762,671 (GRCm39) |
|
probably benign |
Het |
| Gpr19 |
A |
T |
6: 134,847,192 (GRCm39) |
F72I |
possibly damaging |
Het |
| Grin3b |
C |
A |
10: 79,811,716 (GRCm39) |
N740K |
probably damaging |
Het |
| Gstk1 |
A |
T |
6: 42,223,535 (GRCm39) |
T42S |
probably benign |
Het |
| Hoxd1 |
G |
A |
2: 74,594,626 (GRCm39) |
A294T |
probably benign |
Het |
| Hspg2 |
T |
A |
4: 137,275,323 (GRCm39) |
|
probably null |
Het |
| Ift74 |
A |
T |
4: 94,573,940 (GRCm39) |
N472I |
probably benign |
Het |
| Il1a |
C |
T |
2: 129,144,813 (GRCm39) |
D202N |
probably damaging |
Het |
| Islr |
T |
C |
9: 58,064,778 (GRCm39) |
D243G |
probably damaging |
Het |
| Kif21a |
C |
T |
15: 90,843,946 (GRCm39) |
E1098K |
probably damaging |
Het |
| Krtap16-1 |
T |
C |
11: 99,876,852 (GRCm39) |
E184G |
probably damaging |
Het |
| Lrp1b |
A |
G |
2: 41,075,974 (GRCm39) |
I1889T |
possibly damaging |
Het |
| Mcpt4 |
A |
G |
14: 56,297,416 (GRCm39) |
*247Q |
probably null |
Het |
| Megf10 |
T |
C |
18: 57,410,802 (GRCm39) |
|
probably null |
Het |
| Mettl2 |
T |
A |
11: 105,030,544 (GRCm39) |
H373Q |
probably benign |
Het |
| Mocos |
A |
G |
18: 24,816,273 (GRCm39) |
K617E |
probably damaging |
Het |
| Ms4a8a |
A |
G |
19: 11,053,761 (GRCm39) |
I115T |
probably damaging |
Het |
| Ndst1 |
T |
C |
18: 60,828,580 (GRCm39) |
Y658C |
probably damaging |
Het |
| Nin |
G |
A |
12: 70,077,712 (GRCm39) |
A1031V |
probably benign |
Het |
| Nin |
C |
A |
12: 70,092,337 (GRCm39) |
K657N |
possibly damaging |
Het |
| Noc4l |
G |
A |
5: 110,797,713 (GRCm39) |
R344* |
probably null |
Het |
| Notch2 |
T |
C |
3: 98,052,443 (GRCm39) |
S1980P |
probably damaging |
Het |
| Npat |
C |
T |
9: 53,473,960 (GRCm39) |
S584L |
probably benign |
Het |
| Nphp4 |
A |
G |
4: 152,581,121 (GRCm39) |
T102A |
probably damaging |
Het |
| Olfml2b |
A |
G |
1: 170,472,642 (GRCm39) |
N51S |
possibly damaging |
Het |
| Or2n1e |
A |
G |
17: 38,585,932 (GRCm39) |
K90R |
probably benign |
Het |
| Or2y16 |
T |
A |
11: 49,335,116 (GRCm39) |
I146N |
possibly damaging |
Het |
| Or5al1 |
T |
C |
2: 85,990,280 (GRCm39) |
I145V |
probably benign |
Het |
| Or5w22 |
A |
G |
2: 87,362,427 (GRCm39) |
T17A |
probably benign |
Het |
| Pced1b |
T |
A |
15: 97,282,758 (GRCm39) |
W266R |
probably damaging |
Het |
| Pdcd6ip |
A |
G |
9: 113,507,422 (GRCm39) |
V378A |
probably damaging |
Het |
| Pde8b |
T |
A |
13: 95,169,374 (GRCm39) |
K683N |
probably damaging |
Het |
| Pfas |
T |
G |
11: 68,888,872 (GRCm39) |
|
probably null |
Het |
| Pirb |
A |
T |
7: 3,720,637 (GRCm39) |
L287Q |
probably benign |
Het |
| Plcd4 |
T |
G |
1: 74,587,394 (GRCm39) |
S51R |
probably benign |
Het |
| Plekhh2 |
T |
A |
17: 84,884,612 (GRCm39) |
Y775* |
probably null |
Het |
| Polr3a |
G |
A |
14: 24,534,232 (GRCm39) |
P91L |
probably damaging |
Het |
| Ppp4r3b |
C |
T |
11: 29,163,765 (GRCm39) |
T47I |
possibly damaging |
Het |
| Pter |
A |
T |
2: 12,999,572 (GRCm39) |
D169V |
probably damaging |
Het |
| Ptpn12 |
A |
G |
5: 21,203,168 (GRCm39) |
S537P |
probably benign |
Het |
| Ptpru |
T |
A |
4: 131,506,361 (GRCm39) |
D1067V |
probably damaging |
Het |
| Rcn1 |
A |
T |
2: 105,229,350 (GRCm39) |
D67E |
probably damaging |
Het |
| Rfc4 |
T |
C |
16: 22,932,983 (GRCm39) |
E318G |
probably benign |
Het |
| Samd13 |
C |
A |
3: 146,368,469 (GRCm39) |
R41L |
probably benign |
Het |
| Shoc1 |
T |
C |
4: 59,113,926 (GRCm39) |
K13R |
unknown |
Het |
| Slc6a2 |
T |
C |
8: 93,699,440 (GRCm39) |
I156T |
possibly damaging |
Het |
| Spag16 |
T |
C |
1: 70,036,015 (GRCm39) |
F348L |
probably benign |
Het |
| Spag4 |
T |
C |
2: 155,907,342 (GRCm39) |
Y21H |
probably damaging |
Het |
| Stam2 |
G |
A |
2: 52,593,187 (GRCm39) |
A368V |
possibly damaging |
Het |
| Stc1 |
A |
T |
14: 69,275,776 (GRCm39) |
M190L |
probably benign |
Het |
| Stxbp1 |
A |
G |
2: 32,690,629 (GRCm39) |
L475P |
probably damaging |
Het |
| Syn3 |
A |
T |
10: 85,916,075 (GRCm39) |
Y304N |
probably damaging |
Het |
| Tbc1d15 |
G |
T |
10: 115,056,219 (GRCm39) |
T251K |
probably benign |
Het |
| Tbpl2 |
A |
T |
2: 23,985,057 (GRCm39) |
M29K |
probably benign |
Het |
| Tead3 |
T |
G |
17: 28,553,698 (GRCm39) |
Q170H |
possibly damaging |
Het |
| Tpbpb |
T |
C |
13: 61,049,977 (GRCm39) |
N51D |
probably benign |
Het |
| Tstd3 |
A |
G |
4: 21,759,400 (GRCm39) |
M124T |
probably benign |
Het |
| Ttyh1 |
T |
A |
7: 4,122,695 (GRCm39) |
H14Q |
possibly damaging |
Het |
| Tubgcp4 |
G |
A |
2: 121,020,374 (GRCm39) |
W449* |
probably null |
Het |
| Txndc11 |
A |
G |
16: 10,905,639 (GRCm39) |
|
probably null |
Het |
| Usp24 |
T |
A |
4: 106,296,024 (GRCm39) |
D2615E |
probably damaging |
Het |
| Vars1 |
A |
G |
17: 35,233,734 (GRCm39) |
E1020G |
possibly damaging |
Het |
| Vmn2r58 |
A |
G |
7: 41,509,951 (GRCm39) |
I542T |
probably benign |
Het |
| Vwf |
A |
G |
6: 125,620,032 (GRCm39) |
Y1570C |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,662,863 (GRCm39) |
Y2749F |
possibly damaging |
Het |
| Zfand1 |
A |
C |
3: 10,406,115 (GRCm39) |
V198G |
possibly damaging |
Het |
| Zfp536 |
G |
A |
7: 37,268,879 (GRCm39) |
T179I |
probably damaging |
Het |
| Zfp599 |
T |
C |
9: 22,161,700 (GRCm39) |
Y155C |
probably benign |
Het |
|
| Other mutations in Dab1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00087:Dab1
|
APN |
4 |
104,535,950 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00087:Dab1
|
APN |
4 |
104,536,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00328:Dab1
|
APN |
4 |
104,545,635 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
IGL00756:Dab1
|
APN |
4 |
104,585,075 (GRCm39) |
missense |
probably benign |
|
|
IGL02074:Dab1
|
APN |
4 |
104,585,051 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02286:Dab1
|
APN |
4 |
104,537,267 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02986:Dab1
|
APN |
4 |
104,336,418 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03008:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03133:Dab1
|
APN |
4 |
104,584,777 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL03375:Dab1
|
APN |
4 |
104,538,798 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
LCD18:Dab1
|
UTSW |
4 |
103,903,769 (GRCm39) |
intron |
probably benign |
|
|
R0027:Dab1
|
UTSW |
4 |
104,561,396 (GRCm39) |
intron |
probably benign |
|
|
R0466:Dab1
|
UTSW |
4 |
104,577,747 (GRCm39) |
missense |
probably benign |
0.15 |
|
R0838:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R0840:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1086:Dab1
|
UTSW |
4 |
104,185,769 (GRCm39) |
intron |
probably benign |
|
|
R1598:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1640:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1749:Dab1
|
UTSW |
4 |
104,185,495 (GRCm39) |
intron |
probably benign |
|
|
R1770:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1846:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1847:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1848:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1885:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1986:Dab1
|
UTSW |
4 |
104,470,412 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1990:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2006:Dab1
|
UTSW |
4 |
104,462,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2030:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2032:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2034:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2061:Dab1
|
UTSW |
4 |
104,535,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2088:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2089:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2091:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2092:Dab1
|
UTSW |
4 |
104,535,974 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2194:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2361:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2362:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2391:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2424:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R2865:Dab1
|
UTSW |
4 |
104,537,343 (GRCm39) |
missense |
probably benign |
|
|
R3118:Dab1
|
UTSW |
4 |
104,537,266 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R3716:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3718:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3740:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3742:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R3965:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4057:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4393:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4396:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4418:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4607:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4608:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4648:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4693:Dab1
|
UTSW |
4 |
104,536,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4701:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4730:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R4760:Dab1
|
UTSW |
4 |
104,589,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4927:Dab1
|
UTSW |
4 |
104,561,449 (GRCm39) |
missense |
probably benign |
|
|
R5173:Dab1
|
UTSW |
4 |
104,545,645 (GRCm39) |
splice site |
probably null |
|
|
R5503:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6199:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6200:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6207:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6224:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6227:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6228:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6229:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6246:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6247:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6248:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6249:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6250:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6258:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6259:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6260:Dab1
|
UTSW |
4 |
104,588,948 (GRCm39) |
missense |
probably benign |
0.29 |
|
R6505:Dab1
|
UTSW |
4 |
104,369,461 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6817:Dab1
|
UTSW |
4 |
104,536,743 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7305:Dab1
|
UTSW |
4 |
104,570,987 (GRCm39) |
missense |
|
|
|
R7709:Dab1
|
UTSW |
4 |
104,577,756 (GRCm39) |
nonsense |
probably null |
|
|
R7894:Dab1
|
UTSW |
4 |
104,589,335 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8142:Dab1
|
UTSW |
4 |
104,535,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8462:Dab1
|
UTSW |
4 |
104,561,404 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8472:Dab1
|
UTSW |
4 |
104,336,439 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9138:Dab1
|
UTSW |
4 |
104,588,929 (GRCm39) |
nonsense |
probably null |
|
|
R9311:Dab1
|
UTSW |
4 |
104,369,463 (GRCm39) |
critical splice donor site |
probably null |
|
|
RF017:Dab1
|
UTSW |
4 |
104,570,849 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1088:Dab1
|
UTSW |
4 |
104,336,429 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Z1176:Dab1
|
UTSW |
4 |
104,585,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dab1
|
UTSW |
4 |
104,584,937 (GRCm39) |
missense |
probably benign |
0.05 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGCTTGCTTGTGTGTCAGAAG -3'
(R):5'- GCCTGTGATCCATCAGGCTAGAAC -3'
Sequencing Primer
(F):5'- TGACTCAGTAGCTCTCCAGTAGG -3'
(R):5'- TTTACAGGAGGCTGAAACTTCCC -3'
|
| Posted On |
2014-05-14 |
Incidental Mutation