Mutagenetix > Incidental Mutation

Incidental Mutation 'R1760:Fsip2'

192660

Institutional Source

Beutler Lab

Gene Symbol

Fsip2

Ensembl Gene

ENSMUSG00000075249

Gene Name

fibrous sheath-interacting protein 2

Synonyms

OTTMUSG00000013335

MMRRC Submission

039792-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.174) question?

Stock #

R1760 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

82943634-83008937 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 82984896 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Methionine at position 3658 (V3658M)

Ref Sequence

ENSEMBL: ENSMUSP00000120314 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000143764]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000132967

SMART Domains

Protein: ENSMUSP00000122350
Gene: ENSMUSG00000075249

Domain	Start	End	E-Value	Type
low complexity region	22	38	N/A	INTRINSIC
low complexity region	79	90	N/A	INTRINSIC
low complexity region	381	392	N/A	INTRINSIC
low complexity region	411	430	N/A	INTRINSIC
low complexity region	735	746	N/A	INTRINSIC
low complexity region	953	962	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000143764
AA Change: V3658M

PolyPhen 2 Score 0.073 (Sensitivity: 0.93; Specificity: 0.84)

SMART Domains

Protein: ENSMUSP00000120314
Gene: ENSMUSG00000075249
AA Change: V3658M

Domain	Start	End	E-Value	Type
coiled coil region	271	297	N/A	INTRINSIC
low complexity region	544	561	N/A	INTRINSIC
low complexity region	586	597	N/A	INTRINSIC
low complexity region	882	895	N/A	INTRINSIC
low complexity region	925	939	N/A	INTRINSIC
low complexity region	1115	1120	N/A	INTRINSIC
low complexity region	1531	1545	N/A	INTRINSIC
low complexity region	2044	2057	N/A	INTRINSIC
low complexity region	2507	2523	N/A	INTRINSIC
low complexity region	2564	2575	N/A	INTRINSIC
low complexity region	2866	2877	N/A	INTRINSIC
low complexity region	2896	2915	N/A	INTRINSIC
low complexity region	3220	3231	N/A	INTRINSIC
low complexity region	3438	3447	N/A	INTRINSIC
Pfam:FSIP2	4045	4408	3.5e-42	PFAM
Pfam:FSIP2	4375	4613	7.7e-26	PFAM
Pfam:FSIP2	4622	4932	4.3e-17	PFAM
Pfam:FSIP2	4903	5454	7e-27	PFAM
low complexity region	5507	5522	N/A	INTRINSIC
low complexity region	5769	5780	N/A	INTRINSIC
low complexity region	5834	5846	N/A	INTRINSIC
low complexity region	5851	5867	N/A	INTRINSIC
Pfam:FSIP2	5998	6867	N/A	PFAM
low complexity region	6977	6990	N/A	INTRINSIC

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 97.5%
3x: 96.9%
10x: 95.3%
20x: 92.6%

Validation Efficiency

97% (95/98)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein associated with the sperm fibrous sheath. Genes encoding most of the fibrous-sheath associated proteins genes are transcribed only during the postmeiotic period of spermatogenesis. The protein encoded by this gene is specific to spermatogenic cells. Copy number variation in this gene may be associated with testicular germ cell tumors. Pseudogenes associated with this gene are reported on chromosomes 2 and X. [provided by RefSeq, Aug 2016]

Allele List at MGI

Other mutations in this stock

Total: 90 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca2	T	C	2: 25,443,043 (GRCm38)	S1585P	probably benign	Het
Abhd16b	T	C	2: 181,493,404 (GRCm38)	F33S	probably damaging	Het
Adgra2	G	A	8: 27,119,767 (GRCm38)	R856Q	probably damaging	Het
Aff3	A	T	1: 38,329,864 (GRCm38)		probably benign	Het
Anxa2	A	T	9: 69,489,767 (GRCm38)	Y251F	probably benign	Het
Arid1b	A	G	17: 5,341,813 (GRCm38)	T1873A	probably damaging	Het
Baz1b	C	A	5: 135,242,524 (GRCm38)	D1320E	probably benign	Het
Bbs1	A	T	19: 4,894,322 (GRCm38)	S426R	probably benign	Het
Bid	A	G	6: 120,900,248 (GRCm38)	V44A	possibly damaging	Het
Ccdc60	T	A	5: 116,172,473 (GRCm38)	M177L	probably damaging	Het
Cdh23	G	A	10: 60,326,076 (GRCm38)	T1997M	probably damaging	Het
Cdh5	T	A	8: 104,128,169 (GRCm38)	M243K	probably benign	Het
Clpb	T	A	7: 101,786,698 (GRCm38)	V578E	possibly damaging	Het
Cngb1	C	A	8: 95,299,700 (GRCm38)	C151F	probably benign	Het
Cntnap5b	T	C	1: 99,772,810 (GRCm38)	S16P	probably benign	Het
Cr1l	T	A	1: 195,114,815 (GRCm38)	M305L	probably benign	Het
Ctnnal1	A	T	4: 56,838,988 (GRCm38)	M235K	probably damaging	Het
Ddx55	A	T	5: 124,568,113 (GRCm38)	R534W	probably damaging	Het
Dip2b	T	A	15: 100,212,029 (GRCm38)	L1465Q	probably damaging	Het
Dnah9	G	T	11: 65,981,222 (GRCm38)	D2727E	probably benign	Het
Dph3b-ps	A	C	13: 106,546,989 (GRCm38)		noncoding transcript	Het
Dst	T	A	1: 34,228,603 (GRCm38)	L2702Q	probably damaging	Het
Efnb2	T	C	8: 8,623,184 (GRCm38)	T158A	possibly damaging	Het
Exosc10	A	T	4: 148,578,469 (GRCm38)	K712*	probably null	Het
Fgr	T	C	4: 132,998,342 (GRCm38)	V354A	possibly damaging	Het
Gm1527	G	A	3: 28,895,550 (GRCm38)		probably benign	Het
Gm5150	G	T	3: 16,006,304 (GRCm38)	Q7K	probably benign	Het
Gpr155	C	T	2: 73,381,935 (GRCm38)	V115M	probably damaging	Het
Gpr75	T	C	11: 30,891,527 (GRCm38)	L144P	probably damaging	Het
Gsn	T	A	2: 35,284,823 (GRCm38)	Y127N	probably damaging	Het
Hk1	A	G	10: 62,281,899 (GRCm38)	L615S	probably damaging	Het
Igsf9b	A	G	9: 27,317,827 (GRCm38)	T194A	possibly damaging	Het
Il17rd	C	T	14: 27,091,806 (GRCm38)	Q46*	probably null	Het
Jak1	T	A	4: 101,162,929 (GRCm38)	M678L	probably benign	Het
Kif6	T	C	17: 49,615,283 (GRCm38)	V16A	probably benign	Het
Kpna3	T	C	14: 61,370,541 (GRCm38)	E405G	probably benign	Het
Lmtk2	C	A	5: 144,174,175 (GRCm38)	T571K	probably damaging	Het
Mucl2	T	C	15: 103,897,572 (GRCm38)	T40A	possibly damaging	Het
Myh11	G	A	16: 14,233,695 (GRCm38)		probably benign	Het
Myh7	C	T	14: 54,972,713 (GRCm38)	R1845Q	probably damaging	Het
Myo1f	T	A	17: 33,586,198 (GRCm38)	L480Q	probably benign	Het
Nek9	T	C	12: 85,310,410 (GRCm38)	E660G	probably benign	Het
Nek9	T	G	12: 85,305,590 (GRCm38)	D833A	possibly damaging	Het
Or10z1	C	T	1: 174,250,360 (GRCm38)	C189Y	probably damaging	Het
Or2a12	A	G	6: 42,927,497 (GRCm38)	I89V	possibly damaging	Het
Or2t45	A	G	11: 58,778,369 (GRCm38)	M81V	possibly damaging	Het
Or5h18	T	C	16: 59,026,987 (GRCm38)	R307G	probably benign	Het
Or6c65	T	A	10: 129,767,548 (GRCm38)	D17E	probably benign	Het
Or6f2	G	A	7: 140,176,275 (GRCm38)	V52M	probably damaging	Het
Or7s1a-ps1	T	A	9: 18,932,495 (GRCm38)		probably benign	Het
Otud3	G	T	4: 138,895,781 (GRCm38)	T383K	possibly damaging	Het
Pkp4	T	C	2: 59,311,841 (GRCm38)	L496P	probably damaging	Het
Pla2g4e	C	A	2: 120,170,046 (GRCm38)	A737S	possibly damaging	Het
Pla2g4f	T	C	2: 120,314,066 (GRCm38)		probably benign	Het
Plxnd1	A	T	6: 115,967,779 (GRCm38)	V1018E	possibly damaging	Het
Ppp1r21	T	G	17: 88,562,225 (GRCm38)	V402G	possibly damaging	Het
Prkcq	T	G	2: 11,300,070 (GRCm38)	M690R	probably damaging	Het
Ptpra	T	C	2: 130,549,827 (GRCm38)	I719T	probably damaging	Het
Rab3ip	C	T	10: 116,937,510 (GRCm38)	D133N	probably damaging	Het
Relch	T	G	1: 105,719,444 (GRCm38)		probably benign	Het
Rsbn1	T	A	3: 103,960,031 (GRCm38)	Y563N	probably damaging	Het
Rtf1	A	C	2: 119,728,408 (GRCm38)	D530A	probably benign	Het
Rybp	G	T	6: 100,232,263 (GRCm38)	S199R	probably benign	Het
Sema5a	T	G	15: 32,641,106 (GRCm38)	C689G	probably damaging	Het
Senp6	T	A	9: 80,118,629 (GRCm38)	V314E	probably benign	Het
Setd1a	T	A	7: 127,785,890 (GRCm38)	C47S	possibly damaging	Het
Slamf1	C	A	1: 171,777,166 (GRCm38)	T168K	probably benign	Het
Slc12a5	T	C	2: 164,996,128 (GRCm38)	S937P	probably damaging	Het
Slc38a11	C	T	2: 65,355,319 (GRCm38)		probably null	Het
Slc6a2	C	T	8: 92,961,218 (GRCm38)		probably benign	Het
Snw1	A	T	12: 87,464,689 (GRCm38)	F64Y	probably benign	Het
Spata9	A	C	13: 75,998,524 (GRCm38)	I172L	probably benign	Het
Sphkap	T	C	1: 83,277,544 (GRCm38)	H828R	probably benign	Het
Spmip6	T	A	4: 41,507,330 (GRCm38)		probably null	Het
Tmem94	A	T	11: 115,796,754 (GRCm38)	K1146N	probably damaging	Het
Trdn	A	G	10: 33,233,887 (GRCm38)	T294A	possibly damaging	Het
Tsc22d1	T	C	14: 76,416,948 (GRCm38)	V289A	possibly damaging	Het
Tti1	C	A	2: 157,993,035 (GRCm38)	V1002L	possibly damaging	Het
Tubgcp4	T	A	2: 121,189,471 (GRCm38)		probably null	Het
Ush2a	G	A	1: 188,910,983 (GRCm38)	E4181K	possibly damaging	Het
Uvrag	A	G	7: 98,888,348 (GRCm38)	S547P	probably benign	Het
Vav3	T	C	3: 109,341,127 (GRCm38)	V30A	possibly damaging	Het
Vegfa	A	G	17: 46,025,469 (GRCm38)	Y242H	probably damaging	Het
Vmn2r75	G	T	7: 86,148,811 (GRCm38)	T598K	probably damaging	Het
Vps13b	C	T	15: 35,884,619 (GRCm38)	S3146L	possibly damaging	Het
Vrk3	A	G	7: 44,768,471 (GRCm38)	Y310C	probably damaging	Het
Zfhx4	A	G	3: 5,382,616 (GRCm38)	K1100R	probably benign	Het
Zfp748	T	A	13: 67,545,421 (GRCm38)		probably null	Het
Zfp760	A	T	17: 21,722,330 (GRCm38)	D162V	probably damaging	Het
Znfx1	T	A	2: 167,039,866 (GRCm38)	M1068L	probably damaging	Het

Other mutations in Fsip2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00094:Fsip2	APN	2	82,990,386 (GRCm38)	missense	probably benign	0.18
IGL00557:Fsip2	APN	2	82,991,313 (GRCm38)	missense	possibly damaging	0.53
IGL01343:Fsip2	APN	2	82,999,819 (GRCm38)	missense	possibly damaging	0.53
IGL01387:Fsip2	APN	2	82,992,982 (GRCm38)	missense	possibly damaging	0.71
IGL01523:Fsip2	APN	2	82,977,519 (GRCm38)	missense	probably benign
IGL01554:Fsip2	APN	2	82,977,278 (GRCm38)	missense	possibly damaging	0.68
IGL01650:Fsip2	APN	2	82,991,086 (GRCm38)	missense	probably benign	0.33
IGL01809:Fsip2	APN	2	82,978,347 (GRCm38)	missense	possibly damaging	0.80
IGL01826:Fsip2	APN	2	82,982,639 (GRCm38)	missense	probably benign	0.18
IGL01830:Fsip2	APN	2	82,984,929 (GRCm38)	missense	probably benign
IGL01918:Fsip2	APN	2	82,992,138 (GRCm38)	missense	possibly damaging	0.71
IGL01932:Fsip2	APN	2	82,994,005 (GRCm38)	missense	possibly damaging	0.71
IGL01989:Fsip2	APN	2	82,993,867 (GRCm38)	missense	probably damaging	0.99
IGL02096:Fsip2	APN	2	82,991,860 (GRCm38)	missense	possibly damaging	0.85
IGL02153:Fsip2	APN	2	82,978,721 (GRCm38)	missense	probably benign
IGL02155:Fsip2	APN	2	82,998,352 (GRCm38)	missense	probably benign
IGL02219:Fsip2	APN	2	82,977,830 (GRCm38)	missense	probably benign	0.07
IGL02248:Fsip2	APN	2	82,982,772 (GRCm38)	missense	possibly damaging	0.73
IGL02316:Fsip2	APN	2	82,978,793 (GRCm38)	missense	probably benign
IGL02478:Fsip2	APN	2	82,984,392 (GRCm38)	missense	probably benign	0.00
IGL02504:Fsip2	APN	2	82,978,855 (GRCm38)	missense	possibly damaging	0.83
IGL02572:Fsip2	APN	2	82,992,003 (GRCm38)	missense	probably benign	0.32
IGL02625:Fsip2	APN	2	82,949,492 (GRCm38)	missense	probably benign	0.00
IGL02665:Fsip2	APN	2	82,993,063 (GRCm38)	missense	probably damaging	1.00
IGL02668:Fsip2	APN	2	82,998,318 (GRCm38)	missense	probably benign	0.06
IGL02676:Fsip2	APN	2	82,982,157 (GRCm38)	missense	possibly damaging	0.53
IGL02717:Fsip2	APN	2	82,951,026 (GRCm38)	splice site	probably benign
IGL02805:Fsip2	APN	2	82,993,495 (GRCm38)	missense	probably benign	0.01
IGL02943:Fsip2	APN	2	82,992,357 (GRCm38)	missense	probably benign	0.32
IGL02965:Fsip2	APN	2	82,983,054 (GRCm38)	missense	probably benign	0.33
IGL03001:Fsip2	APN	2	82,990,624 (GRCm38)	intron	probably benign
IGL03076:Fsip2	APN	2	82,982,138 (GRCm38)	missense	possibly damaging	0.96
IGL03229:Fsip2	APN	2	82,978,076 (GRCm38)	missense	possibly damaging	0.86
IGL03353:Fsip2	APN	2	82,977,393 (GRCm38)	missense	possibly damaging	0.85
IGL03401:Fsip2	APN	2	82,990,470 (GRCm38)	missense	probably benign
bubblegum	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
Dao	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
engulf	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
envelope	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
gladius	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
glove	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
Katana	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
scarf	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
Sock	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
swaddle	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
wrap	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
Wrapper	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
D4186:Fsip2	UTSW	2	82,988,412 (GRCm38)	missense	probably benign	0.32
FR4976:Fsip2	UTSW	2	82,984,365 (GRCm38)	critical splice acceptor site	probably benign
FR4976:Fsip2	UTSW	2	82,984,362 (GRCm38)	critical splice acceptor site	probably benign
PIT4382001:Fsip2	UTSW	2	82,990,852 (GRCm38)	missense	possibly damaging	0.86
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0017:Fsip2	UTSW	2	82,992,072 (GRCm38)	missense	probably damaging	0.98
R0021:Fsip2	UTSW	2	82,999,857 (GRCm38)	splice site	probably benign
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,986,955 (GRCm38)	missense	possibly damaging	0.85
R0054:Fsip2	UTSW	2	82,976,608 (GRCm38)	missense	probably damaging	0.96
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0104:Fsip2	UTSW	2	82,978,973 (GRCm38)	missense	possibly damaging	0.91
R0127:Fsip2	UTSW	2	82,984,925 (GRCm38)	missense	probably benign	0.28
R0131:Fsip2	UTSW	2	82,991,121 (GRCm38)	missense	probably benign
R0149:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0167:Fsip2	UTSW	2	82,980,807 (GRCm38)	missense	possibly damaging	0.53
R0190:Fsip2	UTSW	2	82,985,177 (GRCm38)	missense	possibly damaging	0.73
R0323:Fsip2	UTSW	2	82,985,896 (GRCm38)	missense	probably benign	0.33
R0358:Fsip2	UTSW	2	82,983,333 (GRCm38)	missense	possibly damaging	0.56
R0361:Fsip2	UTSW	2	82,975,505 (GRCm38)	missense	possibly damaging	0.93
R0369:Fsip2	UTSW	2	82,984,564 (GRCm38)	missense	probably benign	0.33
R0394:Fsip2	UTSW	2	82,991,075 (GRCm38)	missense	possibly damaging	0.70
R0532:Fsip2	UTSW	2	82,977,785 (GRCm38)	missense	probably benign	0.33
R0595:Fsip2	UTSW	2	82,946,952 (GRCm38)	missense	probably damaging	0.99
R0613:Fsip2	UTSW	2	82,993,795 (GRCm38)	missense	probably damaging	0.99
R0614:Fsip2	UTSW	2	82,977,533 (GRCm38)	missense	probably benign	0.15
R0619:Fsip2	UTSW	2	82,944,140 (GRCm38)	missense	probably damaging	1.00
R0626:Fsip2	UTSW	2	82,988,958 (GRCm38)	missense	probably benign	0.06
R0644:Fsip2	UTSW	2	82,976,897 (GRCm38)	missense	probably benign	0.02
R0661:Fsip2	UTSW	2	82,986,169 (GRCm38)	missense	possibly damaging	0.92
R0680:Fsip2	UTSW	2	82,991,359 (GRCm38)	missense	possibly damaging	0.73
R0688:Fsip2	UTSW	2	82,982,339 (GRCm38)	missense	probably benign	0.18
R0881:Fsip2	UTSW	2	82,986,273 (GRCm38)	missense	possibly damaging	0.52
R0919:Fsip2	UTSW	2	82,985,484 (GRCm38)	missense	possibly damaging	0.53
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0973:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0974:Fsip2	UTSW	2	82,977,092 (GRCm38)	missense	probably benign	0.05
R0976:Fsip2	UTSW	2	82,998,031 (GRCm38)	missense	possibly damaging	0.92
R1025:Fsip2	UTSW	2	82,989,436 (GRCm38)	nonsense	probably null
R1026:Fsip2	UTSW	2	82,988,461 (GRCm38)	missense	possibly damaging	0.52
R1140:Fsip2	UTSW	2	82,975,034 (GRCm38)	missense	probably damaging	0.99
R1170:Fsip2	UTSW	2	82,991,500 (GRCm38)	missense	possibly damaging	0.72
R1180:Fsip2	UTSW	2	82,975,226 (GRCm38)	missense	probably damaging	0.99
R1188:Fsip2	UTSW	2	82,975,017 (GRCm38)	missense	possibly damaging	0.96
R1226:Fsip2	UTSW	2	82,981,011 (GRCm38)	missense	probably damaging	0.96
R1248:Fsip2	UTSW	2	82,989,763 (GRCm38)	missense	possibly damaging	0.93
R1273:Fsip2	UTSW	2	82,989,408 (GRCm38)	missense	possibly damaging	0.92
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1323:Fsip2	UTSW	2	82,985,752 (GRCm38)	missense	probably damaging	1.00
R1356:Fsip2	UTSW	2	82,989,745 (GRCm38)	missense	probably benign	0.38
R1413:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R1430:Fsip2	UTSW	2	82,998,063 (GRCm38)	missense	possibly damaging	0.71
R1475:Fsip2	UTSW	2	82,987,195 (GRCm38)	missense	probably damaging	0.99
R1489:Fsip2	UTSW	2	82,979,811 (GRCm38)	missense	probably benign
R1520:Fsip2	UTSW	2	82,980,714 (GRCm38)	missense	possibly damaging	0.96
R1543:Fsip2	UTSW	2	82,981,587 (GRCm38)	missense	possibly damaging	0.91
R1581:Fsip2	UTSW	2	82,986,282 (GRCm38)	missense	probably damaging	0.98
R1590:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R1646:Fsip2	UTSW	2	82,978,517 (GRCm38)	missense	probably benign	0.07
R1678:Fsip2	UTSW	2	82,986,345 (GRCm38)	missense	probably benign
R1700:Fsip2	UTSW	2	82,991,737 (GRCm38)	missense	probably benign	0.33
R1717:Fsip2	UTSW	2	82,974,945 (GRCm38)	missense	possibly damaging	0.68
R1741:Fsip2	UTSW	2	82,989,912 (GRCm38)	missense	probably benign	0.32
R1760:Fsip2	UTSW	2	82,999,841 (GRCm38)	missense	possibly damaging	0.85
R1760:Fsip2	UTSW	2	82,987,711 (GRCm38)	missense	possibly damaging	0.71
R1789:Fsip2	UTSW	2	82,977,562 (GRCm38)	missense	probably benign	0.00
R1850:Fsip2	UTSW	2	82,984,589 (GRCm38)	missense	possibly damaging	0.72
R1854:Fsip2	UTSW	2	82,993,257 (GRCm38)	missense	possibly damaging	0.84
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1888:Fsip2	UTSW	2	82,944,160 (GRCm38)	missense	probably benign	0.04
R1905:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1907:Fsip2	UTSW	2	82,983,428 (GRCm38)	missense	possibly damaging	0.93
R1920:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,986,820 (GRCm38)	missense	probably benign	0.04
R1921:Fsip2	UTSW	2	82,980,783 (GRCm38)	nonsense	probably null
R1931:Fsip2	UTSW	2	82,986,733 (GRCm38)	missense	probably damaging	0.99
R1934:Fsip2	UTSW	2	82,980,558 (GRCm38)	missense	possibly damaging	0.91
R1959:Fsip2	UTSW	2	82,991,550 (GRCm38)	missense	probably benign
R1965:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1966:Fsip2	UTSW	2	82,992,780 (GRCm38)	missense	possibly damaging	0.86
R1983:Fsip2	UTSW	2	82,979,831 (GRCm38)	missense	probably benign
R1988:Fsip2	UTSW	2	82,976,517 (GRCm38)	missense	possibly damaging	0.56
R2016:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2017:Fsip2	UTSW	2	82,982,732 (GRCm38)	missense	possibly damaging	0.53
R2026:Fsip2	UTSW	2	82,989,444 (GRCm38)	missense	possibly damaging	0.71
R2034:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R2037:Fsip2	UTSW	2	82,978,512 (GRCm38)	missense	probably damaging	0.99
R2070:Fsip2	UTSW	2	82,976,355 (GRCm38)	missense	probably damaging	0.98
R2072:Fsip2	UTSW	2	83,008,815 (GRCm38)	missense	possibly damaging	0.53
R2075:Fsip2	UTSW	2	82,988,579 (GRCm38)	missense	possibly damaging	0.85
R2143:Fsip2	UTSW	2	82,990,271 (GRCm38)	missense	possibly damaging	0.93
R2207:Fsip2	UTSW	2	82,977,479 (GRCm38)	missense	probably benign	0.02
R2256:Fsip2	UTSW	2	82,962,751 (GRCm38)	missense	probably benign	0.07
R2315:Fsip2	UTSW	2	82,975,093 (GRCm38)	missense	probably benign
R2344:Fsip2	UTSW	2	82,989,913 (GRCm38)	missense	possibly damaging	0.71
R2377:Fsip2	UTSW	2	82,976,249 (GRCm38)	missense	probably benign	0.29
R2403:Fsip2	UTSW	2	82,980,720 (GRCm38)	missense	possibly damaging	0.53
R2441:Fsip2	UTSW	2	82,985,341 (GRCm38)	missense	possibly damaging	0.53
R2504:Fsip2	UTSW	2	82,979,610 (GRCm38)	missense	possibly damaging	0.86
R2510:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,986,438 (GRCm38)	missense	probably benign
R2511:Fsip2	UTSW	2	82,951,657 (GRCm38)	missense	probably damaging	1.00
R2512:Fsip2	UTSW	2	82,978,167 (GRCm38)	missense	probably benign	0.04
R2568:Fsip2	UTSW	2	82,990,431 (GRCm38)	missense	probably benign	0.14
R2656:Fsip2	UTSW	2	82,979,045 (GRCm38)	missense	possibly damaging	0.83
R2883:Fsip2	UTSW	2	82,991,524 (GRCm38)	missense	possibly damaging	0.86
R3417:Fsip2	UTSW	2	82,986,510 (GRCm38)	missense	possibly damaging	0.51
R3431:Fsip2	UTSW	2	82,992,010 (GRCm38)	missense	possibly damaging	0.85
R3441:Fsip2	UTSW	2	82,986,727 (GRCm38)	missense	probably benign	0.00
R3605:Fsip2	UTSW	2	82,984,909 (GRCm38)	missense	probably benign	0.28
R3620:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3621:Fsip2	UTSW	2	82,980,258 (GRCm38)	missense	probably benign	0.00
R3726:Fsip2	UTSW	2	82,988,967 (GRCm38)	missense	possibly damaging	0.84
R3755:Fsip2	UTSW	2	82,978,217 (GRCm38)	missense	probably benign	0.26
R3789:Fsip2	UTSW	2	82,982,714 (GRCm38)	missense	probably damaging	0.96
R3836:Fsip2	UTSW	2	82,950,946 (GRCm38)	missense	probably damaging	1.00
R3844:Fsip2	UTSW	2	82,989,606 (GRCm38)	missense	possibly damaging	0.52
R3846:Fsip2	UTSW	2	82,986,415 (GRCm38)	missense	possibly damaging	0.52
R3861:Fsip2	UTSW	2	82,984,776 (GRCm38)	missense	probably damaging	0.98
R3981:Fsip2	UTSW	2	82,958,662 (GRCm38)	missense	probably benign	0.08
R4014:Fsip2	UTSW	2	82,983,518 (GRCm38)	missense	probably benign
R4042:Fsip2	UTSW	2	82,983,552 (GRCm38)	missense	probably benign	0.02
R4075:Fsip2	UTSW	2	82,982,901 (GRCm38)	missense	probably benign	0.26
R4154:Fsip2	UTSW	2	82,987,069 (GRCm38)	missense	possibly damaging	0.71
R4210:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4211:Fsip2	UTSW	2	82,975,149 (GRCm38)	missense	probably damaging	0.99
R4327:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R4332:Fsip2	UTSW	2	82,977,857 (GRCm38)	missense	probably benign	0.00
R4440:Fsip2	UTSW	2	82,991,206 (GRCm38)	missense	possibly damaging	0.85
R4454:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4455:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4457:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4458:Fsip2	UTSW	2	82,990,776 (GRCm38)	missense	possibly damaging	0.70
R4540:Fsip2	UTSW	2	82,951,665 (GRCm38)	missense	probably benign
R4549:Fsip2	UTSW	2	82,989,628 (GRCm38)	missense	probably damaging	0.99
R4558:Fsip2	UTSW	2	82,984,953 (GRCm38)	missense	possibly damaging	0.73
R4573:Fsip2	UTSW	2	82,986,166 (GRCm38)	missense	possibly damaging	0.71
R4583:Fsip2	UTSW	2	82,978,673 (GRCm38)	missense	probably benign	0.33
R4618:Fsip2	UTSW	2	82,987,759 (GRCm38)	missense	probably benign
R4700:Fsip2	UTSW	2	82,987,029 (GRCm38)	missense	probably benign	0.32
R4716:Fsip2	UTSW	2	82,974,859 (GRCm38)	missense	probably damaging	0.96
R4739:Fsip2	UTSW	2	82,975,353 (GRCm38)	missense	possibly damaging	0.92
R4749:Fsip2	UTSW	2	82,989,285 (GRCm38)	missense	probably benign	0.06
R4791:Fsip2	UTSW	2	82,982,108 (GRCm38)	missense	possibly damaging	0.53
R4793:Fsip2	UTSW	2	82,987,700 (GRCm38)	nonsense	probably null
R4819:Fsip2	UTSW	2	82,988,442 (GRCm38)	missense	probably benign	0.06
R4832:Fsip2	UTSW	2	82,990,171 (GRCm38)	missense	possibly damaging	0.92
R4840:Fsip2	UTSW	2	82,949,395 (GRCm38)	missense	probably benign	0.01
R4840:Fsip2	UTSW	2	82,985,471 (GRCm38)	missense	probably benign	0.26
R4865:Fsip2	UTSW	2	82,990,951 (GRCm38)	missense	possibly damaging	0.86
R4876:Fsip2	UTSW	2	82,974,858 (GRCm38)	missense	possibly damaging	0.91
R4885:Fsip2	UTSW	2	82,988,094 (GRCm38)	missense	probably benign	0.02
R4911:Fsip2	UTSW	2	82,981,493 (GRCm38)	missense	possibly damaging	0.85
R4918:Fsip2	UTSW	2	82,993,770 (GRCm38)	missense	possibly damaging	0.51
R4936:Fsip2	UTSW	2	82,985,040 (GRCm38)	missense	probably benign	0.18
R4950:Fsip2	UTSW	2	82,946,932 (GRCm38)	missense	probably damaging	0.97
R4950:Fsip2	UTSW	2	82,977,414 (GRCm38)	missense	probably benign	0.03
R4959:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4971:Fsip2	UTSW	2	82,985,878 (GRCm38)	missense	probably benign	0.38
R4973:Fsip2	UTSW	2	82,984,825 (GRCm38)	missense	probably benign	0.00
R4976:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5022:Fsip2	UTSW	2	82,979,429 (GRCm38)	missense	probably benign	0.33
R5027:Fsip2	UTSW	2	82,989,133 (GRCm38)	missense	possibly damaging	0.71
R5030:Fsip2	UTSW	2	82,988,492 (GRCm38)	missense	possibly damaging	0.85
R5048:Fsip2	UTSW	2	82,993,150 (GRCm38)	missense	probably damaging	0.97
R5096:Fsip2	UTSW	2	82,991,116 (GRCm38)	missense	probably benign	0.00
R5097:Fsip2	UTSW	2	82,991,985 (GRCm38)	missense	probably benign
R5119:Fsip2	UTSW	2	82,988,191 (GRCm38)	missense	probably damaging	0.99
R5138:Fsip2	UTSW	2	82,981,424 (GRCm38)	missense	probably benign	0.12
R5152:Fsip2	UTSW	2	82,978,572 (GRCm38)	missense	probably benign	0.43
R5174:Fsip2	UTSW	2	82,980,741 (GRCm38)	missense	probably benign	0.07
R5193:Fsip2	UTSW	2	82,982,994 (GRCm38)	missense	possibly damaging	0.53
R5245:Fsip2	UTSW	2	82,993,161 (GRCm38)	missense	probably benign	0.02
R5282:Fsip2	UTSW	2	82,978,581 (GRCm38)	missense	possibly damaging	0.61
R5323:Fsip2	UTSW	2	82,988,145 (GRCm38)	missense	possibly damaging	0.71
R5326:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5378:Fsip2	UTSW	2	82,989,841 (GRCm38)	missense	possibly damaging	0.71
R5380:Fsip2	UTSW	2	82,975,398 (GRCm38)	missense	possibly damaging	0.91
R5396:Fsip2	UTSW	2	82,990,918 (GRCm38)	missense	probably benign	0.00
R5422:Fsip2	UTSW	2	82,982,228 (GRCm38)	missense	probably benign	0.00
R5481:Fsip2	UTSW	2	82,979,886 (GRCm38)	missense	probably benign	0.26
R5482:Fsip2	UTSW	2	82,985,310 (GRCm38)	missense	possibly damaging	0.80
R5513:Fsip2	UTSW	2	82,985,198 (GRCm38)	missense	possibly damaging	0.72
R5513:Fsip2	UTSW	2	82,950,912 (GRCm38)	missense	probably benign	0.07
R5513:Fsip2	UTSW	2	82,950,908 (GRCm38)	missense	probably damaging	1.00
R5536:Fsip2	UTSW	2	82,987,059 (GRCm38)	missense	probably benign	0.25
R5542:Fsip2	UTSW	2	82,981,863 (GRCm38)	missense	possibly damaging	0.84
R5553:Fsip2	UTSW	2	82,962,746 (GRCm38)	missense	probably benign
R5568:Fsip2	UTSW	2	82,986,564 (GRCm38)	missense	probably benign	0.25
R5581:Fsip2	UTSW	2	82,998,128 (GRCm38)	missense	possibly damaging	0.84
R5664:Fsip2	UTSW	2	82,988,095 (GRCm38)	missense	probably benign	0.05
R5672:Fsip2	UTSW	2	82,987,494 (GRCm38)	nonsense	probably null
R5712:Fsip2	UTSW	2	83,008,848 (GRCm38)	missense	possibly damaging	0.73
R5762:Fsip2	UTSW	2	82,977,916 (GRCm38)	missense	probably benign	0.33
R5772:Fsip2	UTSW	2	82,984,740 (GRCm38)	missense	probably benign
R5881:Fsip2	UTSW	2	82,984,441 (GRCm38)	missense	possibly damaging	0.72
R5919:Fsip2	UTSW	2	82,992,609 (GRCm38)	missense	possibly damaging	0.71
R5920:Fsip2	UTSW	2	82,988,508 (GRCm38)	nonsense	probably null
R5934:Fsip2	UTSW	2	82,986,748 (GRCm38)	missense	possibly damaging	0.86
R5938:Fsip2	UTSW	2	82,977,491 (GRCm38)	missense	probably benign	0.00
R5974:Fsip2	UTSW	2	82,963,313 (GRCm38)	missense	possibly damaging	0.68
R5991:Fsip2	UTSW	2	82,990,468 (GRCm38)	missense	probably benign	0.28
R6019:Fsip2	UTSW	2	82,987,939 (GRCm38)	missense	possibly damaging	0.52
R6020:Fsip2	UTSW	2	82,992,127 (GRCm38)	missense	probably damaging	0.99
R6056:Fsip2	UTSW	2	82,985,673 (GRCm38)	missense	probably benign	0.01
R6057:Fsip2	UTSW	2	82,979,433 (GRCm38)	missense	probably damaging	0.99
R6139:Fsip2	UTSW	2	82,991,044 (GRCm38)	missense	possibly damaging	0.85
R6145:Fsip2	UTSW	2	82,993,768 (GRCm38)	missense	possibly damaging	0.71
R6160:Fsip2	UTSW	2	82,987,945 (GRCm38)	nonsense	probably null
R6161:Fsip2	UTSW	2	82,987,257 (GRCm38)	missense	possibly damaging	0.80
R6166:Fsip2	UTSW	2	82,980,727 (GRCm38)	missense	probably benign	0.00
R6187:Fsip2	UTSW	2	82,982,454 (GRCm38)	missense	probably benign	0.33
R6196:Fsip2	UTSW	2	82,989,883 (GRCm38)	missense	possibly damaging	0.71
R6217:Fsip2	UTSW	2	82,988,418 (GRCm38)	missense	possibly damaging	0.93
R6276:Fsip2	UTSW	2	82,980,441 (GRCm38)	missense	possibly damaging	0.91
R6278:Fsip2	UTSW	2	82,988,898 (GRCm38)	missense	probably benign	0.16
R6349:Fsip2	UTSW	2	82,993,072 (GRCm38)	missense	probably benign	0.05
R6351:Fsip2	UTSW	2	82,992,684 (GRCm38)	missense	possibly damaging	0.51
R6401:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6404:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6405:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6437:Fsip2	UTSW	2	82,983,492 (GRCm38)	missense	possibly damaging	0.73
R6478:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6479:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6480:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6481:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6521:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6529:Fsip2	UTSW	2	82,982,313 (GRCm38)	missense	probably benign
R6621:Fsip2	UTSW	2	82,989,814 (GRCm38)	missense	possibly damaging	0.93
R6639:Fsip2	UTSW	2	82,983,227 (GRCm38)	missense	possibly damaging	0.85
R6649:Fsip2	UTSW	2	82,967,817 (GRCm38)	missense	possibly damaging	0.83
R6714:Fsip2	UTSW	2	82,990,086 (GRCm38)	missense	possibly damaging	0.71
R6714:Fsip2	UTSW	2	82,979,534 (GRCm38)	missense	probably benign	0.01
R6749:Fsip2	UTSW	2	82,978,394 (GRCm38)	missense	possibly damaging	0.85
R6765:Fsip2	UTSW	2	82,986,432 (GRCm38)	missense	probably benign
R6790:Fsip2	UTSW	2	82,990,939 (GRCm38)	missense	possibly damaging	0.53
R6793:Fsip2	UTSW	2	82,989,494 (GRCm38)	missense	probably benign	0.43
R6795:Fsip2	UTSW	2	82,980,959 (GRCm38)	missense	probably benign	0.08
R6818:Fsip2	UTSW	2	82,985,200 (GRCm38)	missense	probably benign	0.04
R6844:Fsip2	UTSW	2	82,983,625 (GRCm38)	missense	possibly damaging	0.72
R6848:Fsip2	UTSW	2	82,982,787 (GRCm38)	missense	probably benign	0.26
R6945:Fsip2	UTSW	2	82,992,840 (GRCm38)	missense	probably benign	0.16
R6950:Fsip2	UTSW	2	82,985,988 (GRCm38)	missense	probably benign	0.03
R6951:Fsip2	UTSW	2	82,981,949 (GRCm38)	missense	possibly damaging	0.68
R6974:Fsip2	UTSW	2	82,978,717 (GRCm38)	missense	probably damaging	0.96
R6987:Fsip2	UTSW	2	82,948,286 (GRCm38)	nonsense	probably null
R6989:Fsip2	UTSW	2	82,976,954 (GRCm38)	missense	probably benign	0.00
R7001:Fsip2	UTSW	2	82,986,925 (GRCm38)	missense	probably damaging	1.00
R7002:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.86
R7016:Fsip2	UTSW	2	82,990,635 (GRCm38)	missense	probably benign	0.25
R7066:Fsip2	UTSW	2	82,990,891 (GRCm38)	missense	possibly damaging	0.86
R7067:Fsip2	UTSW	2	82,980,734 (GRCm38)	missense	possibly damaging	0.85
R7077:Fsip2	UTSW	2	82,983,152 (GRCm38)	missense	probably benign	0.18
R7099:Fsip2	UTSW	2	82,987,624 (GRCm38)	missense	probably benign
R7126:Fsip2	UTSW	2	82,983,141 (GRCm38)	missense	possibly damaging	0.53
R7156:Fsip2	UTSW	2	82,982,741 (GRCm38)	missense	probably benign	0.00
R7165:Fsip2	UTSW	2	82,981,197 (GRCm38)	missense	possibly damaging	0.77
R7171:Fsip2	UTSW	2	82,986,227 (GRCm38)	nonsense	probably null
R7189:Fsip2	UTSW	2	82,993,237 (GRCm38)	missense	possibly damaging	0.92
R7217:Fsip2	UTSW	2	82,989,068 (GRCm38)	missense	possibly damaging	0.85
R7222:Fsip2	UTSW	2	82,983,671 (GRCm38)	missense	probably benign
R7228:Fsip2	UTSW	2	82,992,307 (GRCm38)	missense	possibly damaging	0.93
R7238:Fsip2	UTSW	2	82,982,140 (GRCm38)	missense	possibly damaging	0.72
R7244:Fsip2	UTSW	2	82,993,263 (GRCm38)	missense	possibly damaging	0.92
R7251:Fsip2	UTSW	2	82,979,081 (GRCm38)	missense	possibly damaging	0.95
R7259:Fsip2	UTSW	2	82,982,130 (GRCm38)	missense	possibly damaging	0.85
R7291:Fsip2	UTSW	2	82,980,519 (GRCm38)	missense	possibly damaging	0.91
R7316:Fsip2	UTSW	2	82,989,691 (GRCm38)	missense	possibly damaging	0.93
R7323:Fsip2	UTSW	2	82,989,516 (GRCm38)	missense	probably benign	0.07
R7335:Fsip2	UTSW	2	82,983,118 (GRCm38)	missense	probably benign
R7343:Fsip2	UTSW	2	82,979,367 (GRCm38)	missense	probably benign	0.07
R7346:Fsip2	UTSW	2	82,998,180 (GRCm38)	missense	probably benign	0.00
R7389:Fsip2	UTSW	2	82,988,796 (GRCm38)	missense	possibly damaging	0.51
R7391:Fsip2	UTSW	2	82,990,319 (GRCm38)	missense	possibly damaging	0.70
R7397:Fsip2	UTSW	2	82,985,257 (GRCm38)	missense	possibly damaging	0.53
R7426:Fsip2	UTSW	2	82,980,097 (GRCm38)	missense	probably damaging	0.98
R7450:Fsip2	UTSW	2	82,951,680 (GRCm38)	missense	probably benign	0.30
R7538:Fsip2	UTSW	2	82,988,550 (GRCm38)	missense	possibly damaging	0.86
R7542:Fsip2	UTSW	2	82,984,852 (GRCm38)	missense	possibly damaging	0.96
R7549:Fsip2	UTSW	2	82,993,993 (GRCm38)	missense	probably damaging	0.99
R7564:Fsip2	UTSW	2	82,989,017 (GRCm38)	missense	probably benign	0.02
R7565:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7583:Fsip2	UTSW	2	82,975,241 (GRCm38)	missense	probably benign	0.12
R7641:Fsip2	UTSW	2	82,986,912 (GRCm38)	nonsense	probably null
R7655:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7656:Fsip2	UTSW	2	82,977,542 (GRCm38)	missense	possibly damaging	0.91
R7665:Fsip2	UTSW	2	82,981,805 (GRCm38)	missense	probably benign	0.03
R7672:Fsip2	UTSW	2	82,990,111 (GRCm38)	missense	possibly damaging	0.93
R7764:Fsip2	UTSW	2	82,980,908 (GRCm38)	missense	possibly damaging	0.93
R7790:Fsip2	UTSW	2	82,988,379 (GRCm38)	missense	probably benign
R7811:Fsip2	UTSW	2	82,998,453 (GRCm38)	missense	possibly damaging	0.93
R7838:Fsip2	UTSW	2	82,976,700 (GRCm38)	missense	probably benign	0.00
R7873:Fsip2	UTSW	2	82,949,512 (GRCm38)	missense	probably damaging	0.97
R7902:Fsip2	UTSW	2	82,977,824 (GRCm38)	missense	possibly damaging	0.72
R7920:Fsip2	UTSW	2	82,951,021 (GRCm38)	missense	possibly damaging	0.94
R7959:Fsip2	UTSW	2	82,985,776 (GRCm38)	missense	possibly damaging	0.51
R8009:Fsip2	UTSW	2	82,988,449 (GRCm38)	missense	possibly damaging	0.85
R8031:Fsip2	UTSW	2	82,986,891 (GRCm38)	missense	probably benign
R8034:Fsip2	UTSW	2	82,989,355 (GRCm38)	missense	possibly damaging	0.92
R8037:Fsip2	UTSW	2	82,985,978 (GRCm38)	missense	possibly damaging	0.72
R8110:Fsip2	UTSW	2	82,958,673 (GRCm38)	missense	probably benign	0.00
R8117:Fsip2	UTSW	2	82,992,952 (GRCm38)	missense	possibly damaging	0.86
R8138:Fsip2	UTSW	2	82,975,797 (GRCm38)	missense	possibly damaging	0.83
R8175:Fsip2	UTSW	2	82,987,677 (GRCm38)	missense	probably benign	0.16
R8175:Fsip2	UTSW	2	82,984,744 (GRCm38)	missense	probably benign	0.06
R8182:Fsip2	UTSW	2	82,976,607 (GRCm38)	missense	probably damaging	0.99
R8206:Fsip2	UTSW	2	82,990,464 (GRCm38)	missense	possibly damaging	0.85
R8229:Fsip2	UTSW	2	82,978,143 (GRCm38)	missense	possibly damaging	0.63
R8239:Fsip2	UTSW	2	82,989,343 (GRCm38)	missense	possibly damaging	0.71
R8245:Fsip2	UTSW	2	82,981,002 (GRCm38)	missense	possibly damaging	0.79
R8303:Fsip2	UTSW	2	82,988,380 (GRCm38)	missense	probably benign	0.00
R8336:Fsip2	UTSW	2	82,990,755 (GRCm38)	missense	possibly damaging	0.53
R8347:Fsip2	UTSW	2	82,987,854 (GRCm38)	missense	probably benign	0.16
R8351:Fsip2	UTSW	2	82,991,895 (GRCm38)	missense	possibly damaging	0.73
R8352:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8419:Fsip2	UTSW	2	82,978,619 (GRCm38)	missense	probably damaging	0.96
R8431:Fsip2	UTSW	2	82,981,566 (GRCm38)	missense	probably damaging	1.00
R8439:Fsip2	UTSW	2	82,977,086 (GRCm38)	missense	probably benign	0.24
R8452:Fsip2	UTSW	2	82,984,593 (GRCm38)	missense	probably benign
R8459:Fsip2	UTSW	2	82,979,678 (GRCm38)	missense	possibly damaging	0.95
R8465:Fsip2	UTSW	2	82,979,940 (GRCm38)	missense	probably benign	0.26
R8473:Fsip2	UTSW	2	82,946,992 (GRCm38)	missense	probably damaging	0.99
R8703:Fsip2	UTSW	2	82,991,527 (GRCm38)	missense	probably damaging	0.98
R8711:Fsip2	UTSW	2	82,984,902 (GRCm38)	missense	possibly damaging	0.53
R8713:Fsip2	UTSW	2	82,981,109 (GRCm38)	missense	probably damaging	1.00
R8789:Fsip2	UTSW	2	82,985,478 (GRCm38)	missense	possibly damaging	0.73
R8805:Fsip2	UTSW	2	82,983,109 (GRCm38)	missense	possibly damaging	0.46
R8840:Fsip2	UTSW	2	82,991,262 (GRCm38)	missense	probably benign	0.03
R8855:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8866:Fsip2	UTSW	2	82,980,177 (GRCm38)	missense	probably benign	0.04
R8875:Fsip2	UTSW	2	82,990,438 (GRCm38)	missense	possibly damaging	0.95
R8883:Fsip2	UTSW	2	82,979,180 (GRCm38)	missense	possibly damaging	0.68
R8903:Fsip2	UTSW	2	82,977,337 (GRCm38)	missense	possibly damaging	0.83
R8907:Fsip2	UTSW	2	82,986,640 (GRCm38)	missense	probably benign	0.20
R8912:Fsip2	UTSW	2	82,980,594 (GRCm38)	missense	probably benign
R8926:Fsip2	UTSW	2	82,993,583 (GRCm38)	missense	possibly damaging	0.84
R8991:Fsip2	UTSW	2	82,985,026 (GRCm38)	missense	probably benign	0.33
R9014:Fsip2	UTSW	2	82,976,554 (GRCm38)	missense	probably benign	0.32
R9014:Fsip2	UTSW	2	82,986,731 (GRCm38)	missense	possibly damaging	0.71
R9039:Fsip2	UTSW	2	82,998,201 (GRCm38)	missense	probably benign	0.32
R9054:Fsip2	UTSW	2	82,975,836 (GRCm38)	missense	possibly damaging	0.68
R9114:Fsip2	UTSW	2	82,976,957 (GRCm38)	missense	probably benign	0.00
R9124:Fsip2	UTSW	2	82,985,759 (GRCm38)	missense	probably benign	0.00
R9131:Fsip2	UTSW	2	82,982,826 (GRCm38)	missense	probably benign
R9149:Fsip2	UTSW	2	82,982,030 (GRCm38)	missense	possibly damaging	0.86
R9180:Fsip2	UTSW	2	82,985,230 (GRCm38)	missense	possibly damaging	0.96
R9192:Fsip2	UTSW	2	82,987,500 (GRCm38)	missense	probably benign	0.06
R9216:Fsip2	UTSW	2	82,990,081 (GRCm38)	missense	probably damaging	0.99
R9218:Fsip2	UTSW	2	82,992,718 (GRCm38)	missense	probably damaging	0.97
R9222:Fsip2	UTSW	2	82,985,614 (GRCm38)	missense	probably benign	0.00
R9262:Fsip2	UTSW	2	82,977,318 (GRCm38)	missense	probably benign	0.00
R9340:Fsip2	UTSW	2	82,988,260 (GRCm38)	missense	possibly damaging	0.71
R9342:Fsip2	UTSW	2	82,988,403 (GRCm38)	missense	possibly damaging	0.71
R9368:Fsip2	UTSW	2	82,980,695 (GRCm38)	missense	possibly damaging	0.68
R9372:Fsip2	UTSW	2	82,992,412 (GRCm38)	missense	possibly damaging	0.71
R9385:Fsip2	UTSW	2	82,989,449 (GRCm38)	missense	possibly damaging	0.84
R9432:Fsip2	UTSW	2	82,975,563 (GRCm38)	missense	probably damaging	0.98
R9434:Fsip2	UTSW	2	82,986,358 (GRCm38)	missense	possibly damaging	0.71
R9445:Fsip2	UTSW	2	82,975,788 (GRCm38)	missense	probably damaging	0.99
R9472:Fsip2	UTSW	2	82,986,941 (GRCm38)	missense	possibly damaging	0.85
R9496:Fsip2	UTSW	2	82,962,718 (GRCm38)	missense	probably benign
R9523:Fsip2	UTSW	2	82,977,628 (GRCm38)	missense	probably damaging	0.99
R9567:Fsip2	UTSW	2	82,967,829 (GRCm38)	missense	probably benign
R9636:Fsip2	UTSW	2	82,990,219 (GRCm38)	missense	possibly damaging	0.52
R9643:Fsip2	UTSW	2	82,991,640 (GRCm38)	missense	possibly damaging	0.53
R9680:Fsip2	UTSW	2	82,988,928 (GRCm38)	missense	probably benign	0.32
R9695:Fsip2	UTSW	2	82,975,882 (GRCm38)	missense	probably benign
R9705:Fsip2	UTSW	2	82,993,290 (GRCm38)	missense	probably benign
R9739:Fsip2	UTSW	2	82,993,552 (GRCm38)	missense	possibly damaging	0.71
R9751:Fsip2	UTSW	2	82,987,897 (GRCm38)	missense	probably benign	0.00
R9761:Fsip2	UTSW	2	82,991,650 (GRCm38)	missense	probably benign	0.00
R9798:Fsip2	UTSW	2	82,979,881 (GRCm38)	nonsense	probably null
RF003:Fsip2	UTSW	2	82,991,521 (GRCm38)	missense	probably benign	0.02
RF005:Fsip2	UTSW	2	82,992,532 (GRCm38)	missense	probably benign	0.04
RF008:Fsip2	UTSW	2	82,977,840 (GRCm38)	missense	probably benign
RF028:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF029:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF036:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
RF038:Fsip2	UTSW	2	82,994,008 (GRCm38)	frame shift	probably null
RF062:Fsip2	UTSW	2	82,984,363 (GRCm38)	critical splice acceptor site	probably benign
X0018:Fsip2	UTSW	2	82,982,507 (GRCm38)	nonsense	probably null
X0020:Fsip2	UTSW	2	82,951,020 (GRCm38)	missense	probably damaging	1.00
X0025:Fsip2	UTSW	2	82,954,946 (GRCm38)	missense	possibly damaging	0.70
X0027:Fsip2	UTSW	2	82,976,778 (GRCm38)	missense	probably benign	0.35
X0066:Fsip2	UTSW	2	82,987,463 (GRCm38)	missense	possibly damaging	0.51
Z1088:Fsip2	UTSW	2	82,988,634 (GRCm38)	missense	possibly damaging	0.85
Z1088:Fsip2	UTSW	2	82,987,653 (GRCm38)	missense	possibly damaging	0.86
Z1088:Fsip2	UTSW	2	82,975,448 (GRCm38)	missense	probably damaging	0.96
Z1176:Fsip2	UTSW	2	82,989,665 (GRCm38)	missense	probably benign	0.02
Z1177:Fsip2	UTSW	2	82,984,524 (GRCm38)	missense	probably damaging	0.98
Z1177:Fsip2	UTSW	2	82,946,960 (GRCm38)	missense	probably damaging	0.99
Z1177:Fsip2	UTSW	2	82,987,203 (GRCm38)	missense	possibly damaging	0.71

Predicted Primers

PCR Primer
(F):5'- GCTGATAAGGCACATCAGGCTTCC -3'
(R):5'- TGCCAGATTTTCCAACAGCTCTGAC -3'

Sequencing Primer
(F):5'- GGCACATCAGGCTTCCATAAAAG -3'
(R):5'- GGAAAGCCCTACATTGTTTGC -3'

Posted On

2014-05-23