Incidental Mutation 'R1761:Cr2'
| ID |
192741 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Cr2
|
| Ensembl Gene |
ENSMUSG00000026616 |
| Gene Name |
complement receptor 2 |
| Synonyms |
C3DR, CD21, Cr-1, Cr1, CD35, Cr-2 |
| MMRRC Submission |
039793-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.140)
|
| Stock # |
R1761 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
195136811-195176716 bp(-) (GRCm38) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 195155123 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000147804
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000082321]
[ENSMUST00000193356]
[ENSMUST00000193801]
[ENSMUST00000195120]
[ENSMUST00000210219]
[ENSMUST00000210219]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably null
Transcript: ENSMUST00000082321
|
| SMART Domains |
Protein: ENSMUSP00000080938
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
1.01e-11 |
SMART |
|
CCP
|
91 |
147 |
9.1e-14 |
SMART |
|
CCP
|
155 |
211 |
1.9e-16 |
SMART |
|
CCP
|
216 |
272 |
1.6e-9 |
SMART |
|
CCP
|
277 |
343 |
1.01e-11 |
SMART |
|
CCP
|
352 |
407 |
1.2e-13 |
SMART |
|
CCP
|
411 |
467 |
2.34e-16 |
SMART |
|
CCP
|
472 |
523 |
1.24e0 |
SMART |
|
CCP
|
528 |
594 |
4.48e-13 |
SMART |
|
CCP
|
603 |
658 |
1.95e-13 |
SMART |
|
CCP
|
718 |
778 |
1.75e-15 |
SMART |
|
CCP
|
787 |
842 |
2.06e-12 |
SMART |
|
CCP
|
850 |
906 |
7.92e-14 |
SMART |
|
CCP
|
911 |
967 |
1.29e-13 |
SMART |
|
transmembrane domain
|
975 |
997 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192604
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193356
|
| SMART Domains |
Protein: ENSMUSP00000141706
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
1 |
46 |
1.2e-1 |
SMART |
|
CCP
|
55 |
110 |
5.9e-16 |
SMART |
|
CCP
|
114 |
170 |
1.1e-18 |
SMART |
|
CCP
|
175 |
226 |
6.1e-3 |
SMART |
|
CCP
|
231 |
297 |
2.2e-15 |
SMART |
|
CCP
|
306 |
361 |
9.4e-16 |
SMART |
|
CCP
|
421 |
481 |
8.3e-18 |
SMART |
|
CCP
|
490 |
545 |
1e-14 |
SMART |
|
CCP
|
553 |
609 |
4e-16 |
SMART |
|
CCP
|
614 |
670 |
6.2e-16 |
SMART |
|
transmembrane domain
|
678 |
700 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193436
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193801
|
| SMART Domains |
Protein: ENSMUSP00000141276
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000195120
|
| SMART Domains |
Protein: ENSMUSP00000141538
Gene: ENSMUSG00000026616
| Domain | Start | End | E-Value | Type |
|---|
|
CCP
|
23 |
82 |
4.9e-14 |
SMART |
|
CCP
|
91 |
147 |
4.5e-16 |
SMART |
|
CCP
|
155 |
211 |
9.1e-19 |
SMART |
|
CCP
|
216 |
272 |
8e-12 |
SMART |
|
CCP
|
277 |
343 |
5e-14 |
SMART |
|
CCP
|
352 |
407 |
5.9e-16 |
SMART |
|
CCP
|
411 |
467 |
1.1e-18 |
SMART |
|
CCP
|
472 |
523 |
6.1e-3 |
SMART |
|
CCP
|
528 |
594 |
2.2e-15 |
SMART |
|
CCP
|
603 |
658 |
9.4e-16 |
SMART |
|
CCP
|
718 |
778 |
8.3e-18 |
SMART |
|
CCP
|
787 |
842 |
1e-14 |
SMART |
|
CCP
|
850 |
906 |
4e-16 |
SMART |
|
CCP
|
911 |
967 |
6.2e-16 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195737
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000210219
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000210219
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a membrane protein, which functions as a receptor for Epstein-Barr virus (EBV) binding on B and T lymphocytes. Genetic variations in this gene are associated with susceptibility to systemic lupus erythematosus type 9 (SLEB9). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Sep 2009]
PHENOTYPE: Homozygotes for targeted null mutations exhibit impaired humoral immune responses to T cell-dependent antigens, with limited affinity maturation, and reduced memory B cell and germinal center formation. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110017D15Rik |
G |
A |
4: 41,507,223 (GRCm38) |
P109L |
probably damaging |
Het |
| Abi3bp |
C |
T |
16: 56,668,309 (GRCm38) |
H1268Y |
possibly damaging |
Het |
| Acan |
T |
A |
7: 79,094,085 (GRCm38) |
Y621* |
probably null |
Het |
| Aig1 |
T |
C |
10: 13,690,584 (GRCm38) |
Y152C |
probably damaging |
Het |
| Arhgap33 |
C |
T |
7: 30,533,063 (GRCm38) |
|
probably null |
Het |
| Bcl6 |
G |
T |
16: 23,977,542 (GRCm38) |
A45D |
probably damaging |
Het |
| Cbx5 |
T |
C |
15: 103,213,180 (GRCm38) |
D10G |
possibly damaging |
Het |
| Ccdc191 |
A |
G |
16: 43,943,510 (GRCm38) |
I445V |
probably benign |
Het |
| Cdk4 |
T |
A |
10: 127,064,677 (GRCm38) |
|
probably benign |
Het |
| Chil6 |
A |
G |
3: 106,394,338 (GRCm38) |
F149L |
probably damaging |
Het |
| Cntn5 |
T |
C |
9: 10,172,054 (GRCm38) |
T42A |
probably benign |
Het |
| Cpn2 |
A |
T |
16: 30,260,196 (GRCm38) |
I229N |
probably damaging |
Het |
| Cpne8 |
A |
G |
15: 90,648,618 (GRCm38) |
V62A |
probably damaging |
Het |
| Crnn |
A |
T |
3: 93,148,651 (GRCm38) |
H248L |
probably benign |
Het |
| Csn1s1 |
A |
G |
5: 87,679,035 (GRCm38) |
S254G |
probably benign |
Het |
| Cubn |
A |
G |
2: 13,489,317 (GRCm38) |
|
probably null |
Het |
| Dnah8 |
A |
G |
17: 30,779,916 (GRCm38) |
N3525S |
probably damaging |
Het |
| Dpp3 |
A |
G |
19: 4,921,149 (GRCm38) |
L220P |
probably benign |
Het |
| Fam110a |
T |
C |
2: 151,970,205 (GRCm38) |
E215G |
probably benign |
Het |
| Fam20a |
A |
T |
11: 109,677,838 (GRCm38) |
N287K |
probably damaging |
Het |
| Fat4 |
T |
C |
3: 38,887,489 (GRCm38) |
V177A |
possibly damaging |
Het |
| Fzd8 |
C |
T |
18: 9,213,643 (GRCm38) |
R242C |
probably damaging |
Het |
| Gimap5 |
A |
T |
6: 48,753,261 (GRCm38) |
Q255L |
probably damaging |
Het |
| Gm13083 |
T |
C |
4: 143,615,868 (GRCm38) |
Y182H |
probably benign |
Het |
| Gm4787 |
A |
G |
12: 81,377,176 (GRCm38) |
L736S |
probably benign |
Het |
| Gmeb1 |
G |
A |
4: 132,234,887 (GRCm38) |
Q154* |
probably null |
Het |
| Gpr156 |
T |
C |
16: 37,987,567 (GRCm38) |
L192P |
probably damaging |
Het |
| Gpr179 |
A |
C |
11: 97,335,106 (GRCm38) |
S2074R |
probably benign |
Het |
| Hddc2 |
G |
T |
10: 31,326,139 (GRCm38) |
D161Y |
probably damaging |
Het |
| Hlcs |
T |
C |
16: 94,268,007 (GRCm38) |
D265G |
probably benign |
Het |
| Hspg2 |
A |
T |
4: 137,514,673 (GRCm38) |
I573F |
possibly damaging |
Het |
| Il1b |
T |
C |
2: 129,365,181 (GRCm38) |
K220E |
probably damaging |
Het |
| Il5 |
T |
C |
11: 53,723,730 (GRCm38) |
I66T |
probably damaging |
Het |
| Irf6 |
G |
A |
1: 193,169,301 (GRCm38) |
R400H |
probably damaging |
Het |
| Klra1 |
A |
T |
6: 130,372,873 (GRCm38) |
Y201N |
probably damaging |
Het |
| Lmf2 |
A |
G |
15: 89,352,713 (GRCm38) |
V442A |
possibly damaging |
Het |
| Mcm2 |
T |
C |
6: 88,889,788 (GRCm38) |
I412M |
possibly damaging |
Het |
| Mlkl |
T |
A |
8: 111,333,723 (GRCm38) |
L18F |
possibly damaging |
Het |
| Mug2 |
C |
A |
6: 122,074,705 (GRCm38) |
H949N |
probably benign |
Het |
| Nf1 |
T |
C |
11: 79,384,265 (GRCm38) |
F51L |
probably damaging |
Het |
| Olfr1049 |
T |
G |
2: 86,255,039 (GRCm38) |
Y218S |
probably damaging |
Het |
| Olfr592 |
T |
G |
7: 103,187,118 (GRCm38) |
C172W |
probably damaging |
Het |
| Olfr77 |
A |
T |
9: 19,921,149 (GRCm38) |
*313C |
probably null |
Het |
| P3h2 |
T |
C |
16: 25,985,050 (GRCm38) |
E322G |
probably damaging |
Het |
| Psmg2 |
CTTCAGTT |
CTTCAGTTCAGTT |
18: 67,646,025 (GRCm38) |
|
probably null |
Het |
| Ptdss1 |
T |
C |
13: 66,956,412 (GRCm38) |
V116A |
possibly damaging |
Het |
| Ranbp2 |
T |
C |
10: 58,485,741 (GRCm38) |
V2620A |
probably benign |
Het |
| Robo2 |
A |
G |
16: 74,035,024 (GRCm38) |
V256A |
probably damaging |
Het |
| Scg3 |
T |
A |
9: 75,676,758 (GRCm38) |
I154F |
probably damaging |
Het |
| Scgn |
A |
T |
13: 23,959,706 (GRCm38) |
F225Y |
probably damaging |
Het |
| Sec61b |
T |
C |
4: 47,480,137 (GRCm38) |
C58R |
possibly damaging |
Het |
| Slc25a46 |
G |
T |
18: 31,607,262 (GRCm38) |
Q96K |
possibly damaging |
Het |
| Sptb |
A |
G |
12: 76,612,608 (GRCm38) |
F1173L |
probably damaging |
Het |
| Srcap |
T |
A |
7: 127,534,845 (GRCm38) |
C893S |
probably damaging |
Het |
| Tet3 |
T |
C |
6: 83,403,659 (GRCm38) |
E509G |
probably damaging |
Het |
| Timm10b |
C |
T |
7: 105,683,708 (GRCm38) |
R897* |
probably null |
Het |
| Tln2 |
C |
T |
9: 67,286,514 (GRCm38) |
A1773T |
probably benign |
Het |
| Tom1 |
T |
C |
8: 75,051,551 (GRCm38) |
V87A |
probably benign |
Het |
| Tti1 |
T |
C |
2: 158,007,697 (GRCm38) |
I541V |
probably benign |
Het |
| Ttn |
A |
T |
2: 76,811,243 (GRCm38) |
L5176Q |
possibly damaging |
Het |
| Tubb1 |
A |
G |
2: 174,456,896 (GRCm38) |
S124G |
probably benign |
Het |
| Vgll3 |
A |
T |
16: 65,839,728 (GRCm38) |
D310V |
probably damaging |
Het |
| Vmac |
A |
G |
17: 56,715,788 (GRCm38) |
L74P |
probably damaging |
Het |
| Zbtb1 |
A |
T |
12: 76,385,821 (GRCm38) |
K194* |
probably null |
Het |
| Zfp429 |
A |
G |
13: 67,396,076 (GRCm38) |
M76T |
probably benign |
Het |
| Zfp808 |
T |
A |
13: 62,171,646 (GRCm38) |
C230S |
possibly damaging |
Het |
| Zfp980 |
A |
G |
4: 145,702,042 (GRCm38) |
Y447C |
probably damaging |
Het |
| Zfp985 |
A |
G |
4: 147,584,045 (GRCm38) |
T457A |
probably benign |
Het |
|
| Other mutations in Cr2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00587:Cr2
|
APN |
1 |
195,154,251 (GRCm38) |
missense |
possibly damaging |
0.76 |
|
IGL01326:Cr2
|
APN |
1 |
195,141,221 (GRCm38) |
missense |
probably null |
1.00 |
|
IGL01358:Cr2
|
APN |
1 |
195,159,820 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01410:Cr2
|
APN |
1 |
195,163,234 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01468:Cr2
|
APN |
1 |
195,168,535 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01608:Cr2
|
APN |
1 |
195,155,220 (GRCm38) |
missense |
possibly damaging |
0.50 |
|
IGL01810:Cr2
|
APN |
1 |
195,159,595 (GRCm38) |
missense |
possibly damaging |
0.49 |
|
IGL01843:Cr2
|
APN |
1 |
195,150,914 (GRCm38) |
splice site |
probably benign |
|
|
IGL02332:Cr2
|
APN |
1 |
195,160,322 (GRCm38) |
missense |
probably benign |
0.19 |
|
IGL02934:Cr2
|
APN |
1 |
195,154,325 (GRCm38) |
splice site |
probably benign |
|
|
IGL02938:Cr2
|
APN |
1 |
195,166,388 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03149:Cr2
|
APN |
1 |
195,166,366 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03327:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL03346:Cr2
|
APN |
1 |
195,169,759 (GRCm38) |
missense |
probably damaging |
1.00 |
|
Pillar
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
PIT4354001:Cr2
|
UTSW |
1 |
195,166,309 (GRCm38) |
missense |
probably damaging |
1.00 |
|
PIT4418001:Cr2
|
UTSW |
1 |
195,157,452 (GRCm38) |
missense |
probably benign |
0.08 |
|
R0128:Cr2
|
UTSW |
1 |
195,166,231 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0130:Cr2
|
UTSW |
1 |
195,166,231 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0380:Cr2
|
UTSW |
1 |
195,157,407 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0538:Cr2
|
UTSW |
1 |
195,160,359 (GRCm38) |
splice site |
probably benign |
|
|
R0605:Cr2
|
UTSW |
1 |
195,163,596 (GRCm38) |
splice site |
probably benign |
|
|
R0626:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.95 |
|
R1135:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1396:Cr2
|
UTSW |
1 |
195,169,253 (GRCm38) |
splice site |
probably null |
|
|
R1422:Cr2
|
UTSW |
1 |
195,171,125 (GRCm38) |
missense |
probably benign |
0.01 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1467:Cr2
|
UTSW |
1 |
195,157,509 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1511:Cr2
|
UTSW |
1 |
195,155,272 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R1572:Cr2
|
UTSW |
1 |
195,163,314 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1714:Cr2
|
UTSW |
1 |
195,151,686 (GRCm38) |
missense |
possibly damaging |
0.46 |
|
R1748:Cr2
|
UTSW |
1 |
195,155,905 (GRCm38) |
nonsense |
probably null |
|
|
R1824:Cr2
|
UTSW |
1 |
195,157,316 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1893:Cr2
|
UTSW |
1 |
195,155,187 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1990:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1991:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R1992:Cr2
|
UTSW |
1 |
195,154,150 (GRCm38) |
missense |
possibly damaging |
0.63 |
|
R2191:Cr2
|
UTSW |
1 |
195,163,381 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2276:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R2277:Cr2
|
UTSW |
1 |
195,157,368 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R3548:Cr2
|
UTSW |
1 |
195,155,888 (GRCm38) |
nonsense |
probably null |
|
|
R3743:Cr2
|
UTSW |
1 |
195,149,966 (GRCm38) |
splice site |
probably benign |
|
|
R3941:Cr2
|
UTSW |
1 |
195,165,814 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R3963:Cr2
|
UTSW |
1 |
195,159,739 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4211:Cr2
|
UTSW |
1 |
195,156,328 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R4484:Cr2
|
UTSW |
1 |
195,154,174 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4546:Cr2
|
UTSW |
1 |
195,171,041 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R4791:Cr2
|
UTSW |
1 |
195,155,935 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4801:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4802:Cr2
|
UTSW |
1 |
195,163,311 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4874:Cr2
|
UTSW |
1 |
195,176,570 (GRCm38) |
missense |
possibly damaging |
0.82 |
|
R4885:Cr2
|
UTSW |
1 |
195,158,731 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
R4889:Cr2
|
UTSW |
1 |
195,176,585 (GRCm38) |
missense |
possibly damaging |
0.70 |
|
R5154:Cr2
|
UTSW |
1 |
195,159,446 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5574:Cr2
|
UTSW |
1 |
195,141,236 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5594:Cr2
|
UTSW |
1 |
195,157,190 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5645:Cr2
|
UTSW |
1 |
195,154,273 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5700:Cr2
|
UTSW |
1 |
195,159,757 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R5929:Cr2
|
UTSW |
1 |
195,171,111 (GRCm38) |
missense |
possibly damaging |
0.91 |
|
R6237:Cr2
|
UTSW |
1 |
195,157,502 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6299:Cr2
|
UTSW |
1 |
195,168,646 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6368:Cr2
|
UTSW |
1 |
195,168,472 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6406:Cr2
|
UTSW |
1 |
195,169,771 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6618:Cr2
|
UTSW |
1 |
195,157,379 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6684:Cr2
|
UTSW |
1 |
195,171,021 (GRCm38) |
nonsense |
probably null |
|
|
R6720:Cr2
|
UTSW |
1 |
195,155,200 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R6866:Cr2
|
UTSW |
1 |
195,151,691 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6915:Cr2
|
UTSW |
1 |
195,171,146 (GRCm38) |
missense |
probably benign |
0.06 |
|
R7057:Cr2
|
UTSW |
1 |
195,151,610 (GRCm38) |
missense |
possibly damaging |
0.83 |
|
R7117:Cr2
|
UTSW |
1 |
195,160,601 (GRCm38) |
missense |
possibly damaging |
0.79 |
|
R7200:Cr2
|
UTSW |
1 |
195,163,249 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7209:Cr2
|
UTSW |
1 |
195,168,724 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7350:Cr2
|
UTSW |
1 |
195,155,286 (GRCm38) |
missense |
probably benign |
0.21 |
|
R7414:Cr2
|
UTSW |
1 |
195,150,036 (GRCm38) |
missense |
probably benign |
|
|
R7453:Cr2
|
UTSW |
1 |
195,165,257 (GRCm38) |
splice site |
probably null |
|
|
R7479:Cr2
|
UTSW |
1 |
195,158,410 (GRCm38) |
critical splice donor site |
probably null |
|
|
R7480:Cr2
|
UTSW |
1 |
195,154,176 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7570:Cr2
|
UTSW |
1 |
195,169,340 (GRCm38) |
nonsense |
probably null |
|
|
R7666:Cr2
|
UTSW |
1 |
195,154,225 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7921:Cr2
|
UTSW |
1 |
195,151,667 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7923:Cr2
|
UTSW |
1 |
195,168,687 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8396:Cr2
|
UTSW |
1 |
195,158,068 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8503:Cr2
|
UTSW |
1 |
195,163,542 (GRCm38) |
missense |
probably benign |
|
|
R8517:Cr2
|
UTSW |
1 |
195,155,899 (GRCm38) |
missense |
probably benign |
0.03 |
|
R8773:Cr2
|
UTSW |
1 |
195,158,605 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8849:Cr2
|
UTSW |
1 |
195,157,239 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8896:Cr2
|
UTSW |
1 |
195,169,273 (GRCm38) |
missense |
possibly damaging |
0.58 |
|
R8938:Cr2
|
UTSW |
1 |
195,171,116 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9027:Cr2
|
UTSW |
1 |
195,151,721 (GRCm38) |
missense |
probably benign |
0.08 |
|
R9045:Cr2
|
UTSW |
1 |
195,155,372 (GRCm38) |
missense |
possibly damaging |
0.61 |
|
R9116:Cr2
|
UTSW |
1 |
195,158,669 (GRCm38) |
nonsense |
probably null |
|
|
R9137:Cr2
|
UTSW |
1 |
195,168,332 (GRCm38) |
critical splice donor site |
probably null |
|
|
R9476:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9497:Cr2
|
UTSW |
1 |
195,168,435 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R9510:Cr2
|
UTSW |
1 |
195,158,108 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9752:Cr2
|
UTSW |
1 |
195,141,267 (GRCm38) |
missense |
probably benign |
0.37 |
|
R9799:Cr2
|
UTSW |
1 |
195,160,680 (GRCm38) |
missense |
probably benign |
0.02 |
|
X0028:Cr2
|
UTSW |
1 |
195,149,982 (GRCm38) |
missense |
probably benign |
0.09 |
|
X0066:Cr2
|
UTSW |
1 |
195,166,321 (GRCm38) |
missense |
probably damaging |
0.99 |
|
Z1176:Cr2
|
UTSW |
1 |
195,154,153 (GRCm38) |
missense |
probably benign |
0.23 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGAAGCTGCACCTCACTAGCAAG -3'
(R):5'- CTAACTCATTGCCCCGATCCAGAAG -3'
Sequencing Primer
(F):5'- GAAGGTCAGCTTCATTCTTCATTAC -3'
(R):5'- GATCCAGAAGTCAAACATGGTTAC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation