Mutagenetix > Incidental Mutation

Incidental Mutation 'R1764:Otogl'

193312

Institutional Source

Beutler Lab

Gene Symbol

Otogl

Ensembl Gene

ENSMUSG00000091455

Gene Name

otogelin-like

Synonyms

Gm6924

MMRRC Submission

039796-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1764 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

107760531-107912134 bp(-) (GRCm38)

Type of Mutation

nonsense

DNA Base Change (assembly)

C to T at 107899461 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Tryptophan to Stop codon at position 154 (W154*)

Ref Sequence

ENSEMBL: ENSMUSP00000129467 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000165341]

AlphaFold

F7A4A7

Predicted Effect

probably null
Transcript: ENSMUST00000165341
AA Change: W154*

SMART Domains

Protein: ENSMUSP00000129467
Gene: ENSMUSG00000091455
AA Change: W154*

Domain	Start	End	E-Value	Type
signal peptide	1	22	N/A	INTRINSIC
EGF_like	71	101	3.36e1	SMART
VWD	104	264	4.74e-29	SMART
C8	305	378	6.13e-6	SMART
VWD	463	625	7e-41	SMART
C8	668	733	3.6e-3	SMART
Pfam:TIL	736	791	2.3e-11	PFAM
SCOP:d1coua_	833	911	1e-6	SMART
VWD	928	1085	1.29e-30	SMART
C8	1120	1194	1.81e-26	SMART
Pfam:AbfB	1230	1350	1.2e-10	PFAM
Pfam:TIL	1364	1418	6.1e-8	PFAM
VWD	1497	1671	2.34e-10	SMART
C8	1705	1775	9.56e-17	SMART
Pfam:TIL	1778	1836	1.6e-8	PFAM
low complexity region	1870	1886	N/A	INTRINSIC
CT	2242	2325	6.9e-14	SMART

Meta Mutation Damage Score

0.9717

Coding Region Coverage

1x: 97.4%
3x: 96.8%
10x: 95.1%
20x: 92.2%

Validation Efficiency

94% (94/100)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to the otogelin family. This gene is expressed in the inner ear of vertebrates with the highest level of expression seen at the embryonic stage and lowest in adult. Knockdown studies in zebrafish suggest that this gene is essential for normal inner ear function. Mutations in this gene are associated with autosomal recessive deafness. [provided by RefSeq, Dec 2012]

Allele List at MGI

Other mutations in this stock

Total: 95 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930522L14Rik	A	G	5: 109,736,789 (GRCm38)	V401A	probably benign	Het
Abca7	G	T	10: 80,008,950 (GRCm38)	W1502L	probably damaging	Het
Adcy7	A	G	8: 88,308,840 (GRCm38)	E124G	probably benign	Het
Aif1l	G	A	2: 31,965,106 (GRCm38)	E66K	probably benign	Het
Aldh8a1	A	T	10: 21,395,493 (GRCm38)	M373L	probably benign	Het
Alg6	T	C	4: 99,741,578 (GRCm38)	Y131H	probably benign	Het
Arhgef6	T	C	X: 57,338,562 (GRCm38)	M5V	probably benign	Het
Arrdc4	A	T	7: 68,741,874 (GRCm38)	I215K	probably damaging	Het
Asb4	A	G	6: 5,390,798 (GRCm38)		probably null	Het
Astn1	T	C	1: 158,504,251 (GRCm38)	I305T	probably benign	Het
Atp5f1b	T	A	10: 128,084,080 (GRCm38)		probably benign	Het
Atp8a1	C	A	5: 67,631,567 (GRCm38)	M1044I	probably benign	Het
Atp9b	C	T	18: 80,909,591 (GRCm38)		probably null	Het
Brd10	T	A	19: 29,719,160 (GRCm38)	T978S	possibly damaging	Het
Btaf1	A	G	19: 36,951,118 (GRCm38)	H113R	probably benign	Het
C87436	G	T	6: 86,453,612 (GRCm38)	C338F	possibly damaging	Het
Casz1	T	C	4: 148,942,900 (GRCm38)		probably benign	Het
Cbr3	T	A	16: 93,690,482 (GRCm38)	H184Q	probably damaging	Het
Cct8l1	T	C	5: 25,517,099 (GRCm38)	S271P	possibly damaging	Het
Cdc34	G	T	10: 79,685,338 (GRCm38)		probably null	Het
Cdc34	A	G	10: 79,685,340 (GRCm38)	K77R	probably benign	Het
Cdh20	A	G	1: 104,934,345 (GRCm38)		probably benign	Het
Celsr3	A	G	9: 108,828,958 (GRCm38)	E880G	probably damaging	Het
Cers1	T	G	8: 70,321,491 (GRCm38)		probably null	Het
Cntn5	T	C	9: 9,673,983 (GRCm38)	I705V	probably benign	Het
Dennd4c	T	A	4: 86,803,010 (GRCm38)	D636E	probably damaging	Het
Dnah11	T	C	12: 118,190,825 (GRCm38)	E240G	probably benign	Het
Dnah2	T	C	11: 69,423,543 (GRCm38)	Y4100C	probably damaging	Het
Dpysl3	T	C	18: 43,363,518 (GRCm38)	E151G	probably damaging	Het
Efcab9	T	G	11: 32,524,457 (GRCm38)	T9P	possibly damaging	Het
Eif4g2	A	T	7: 111,074,487 (GRCm38)	F725Y	probably damaging	Het
Epha6	T	A	16: 59,775,728 (GRCm38)	I867F	probably null	Het
Erbin	T	C	13: 103,843,451 (GRCm38)		probably benign	Het
Evi5l	A	G	8: 4,203,560 (GRCm38)	E468G	probably damaging	Het
Filip1l	C	T	16: 57,570,038 (GRCm38)	R330W	probably damaging	Het
Fmo3	C	T	1: 162,958,573 (GRCm38)	V283M	possibly damaging	Het
Gabarapl1	A	T	6: 129,533,518 (GRCm38)	K24N	possibly damaging	Het
Gigyf1	C	T	5: 137,522,508 (GRCm38)		probably benign	Het
Gm5581	T	A	6: 131,181,399 (GRCm38)		noncoding transcript	Het
Gon4l	G	T	3: 88,892,599 (GRCm38)	K850N	probably damaging	Het
Igf2bp3	C	T	6: 49,109,046 (GRCm38)	R233H	probably damaging	Het
Iqcf4	G	A	9: 106,568,694 (GRCm38)	R85C	probably benign	Het
Kalrn	C	T	16: 34,212,873 (GRCm38)	R473Q	probably damaging	Het
Lmod2	T	A	6: 24,603,377 (GRCm38)	V117E	probably damaging	Het
Mapk11	A	G	15: 89,144,391 (GRCm38)		probably null	Het
Mcm3	G	A	1: 20,805,879 (GRCm38)	R664C	probably damaging	Het
Mex3d	A	G	10: 80,386,936 (GRCm38)	M162T	probably benign	Het
Mrgprb3	A	G	7: 48,643,023 (GRCm38)	I260T	probably benign	Het
Ncor2	G	T	5: 125,028,615 (GRCm38)	A1637D	possibly damaging	Het
Nedd4	T	A	9: 72,730,907 (GRCm38)	D441E	probably damaging	Het
Nek5	A	T	8: 22,109,912 (GRCm38)	C194S	probably damaging	Het
Nos1ap	T	C	1: 170,318,878 (GRCm38)	D369G	possibly damaging	Het
Ntrk1	G	T	3: 87,780,084 (GRCm38)	T681K	probably damaging	Het
Or13a24	T	C	7: 140,574,470 (GRCm38)	W106R	probably damaging	Het
Or4f14	A	G	2: 111,912,181 (GRCm38)	F250L	possibly damaging	Het
Pcdh20	T	C	14: 88,469,184 (GRCm38)	T227A	possibly damaging	Het
Pcdhb17	T	C	18: 37,487,271 (GRCm38)	S705P	probably damaging	Het
Piezo2	T	C	18: 63,124,642 (GRCm38)	H335R	possibly damaging	Het
Pkn2	T	C	3: 142,793,854 (GRCm38)	Q954R	probably damaging	Het
Pramel23	C	A	4: 143,698,270 (GRCm38)	C201F	probably benign	Het
Prkcq	G	A	2: 11,232,631 (GRCm38)	V74M	probably damaging	Het
Prkrip1	A	T	5: 136,189,635 (GRCm38)		probably null	Het
Pttg1ip2	A	T	5: 5,478,943 (GRCm38)	I24N	possibly damaging	Het
Rb1cc1	A	G	1: 6,214,680 (GRCm38)		probably benign	Het
Rbm5	A	T	9: 107,767,564 (GRCm38)	Y11*	probably null	Het
Rsf1	CG	CGACGGCGGTG	7: 97,579,908 (GRCm38)		probably benign	Het
Ryr3	C	A	2: 112,860,460 (GRCm38)	V1082L	probably damaging	Het
Scart2	A	G	7: 140,297,265 (GRCm38)	E831G	probably benign	Het
Sel1l3	C	A	5: 53,170,447 (GRCm38)	E497*	probably null	Het
Serpina6	A	T	12: 103,653,923 (GRCm38)	I189N	probably damaging	Het
Serpinb11	A	T	1: 107,376,802 (GRCm38)	T166S	probably benign	Het
Skint7	T	C	4: 111,982,073 (GRCm38)	L188S	probably benign	Het
Slc25a45	C	T	19: 5,884,930 (GRCm38)	A269V	probably damaging	Het
Sltm	A	G	9: 70,561,800 (GRCm38)	T114A	probably benign	Het
Sned1	G	A	1: 93,281,654 (GRCm38)	V830M	possibly damaging	Het
Spen	C	A	4: 141,472,950 (GRCm38)	V2766L	probably damaging	Het
Srgap2	T	A	1: 131,319,537 (GRCm38)	I445F	possibly damaging	Het
Stox2	A	T	8: 47,194,016 (GRCm38)	Y200*	probably null	Het
Strada	C	A	11: 106,164,184 (GRCm38)	R384L	probably damaging	Het
Tctn2	G	A	5: 124,619,031 (GRCm38)		noncoding transcript	Het
Tgfbr3l	G	T	8: 4,249,282 (GRCm38)	R461L	probably benign	Het
Tmem65	A	G	15: 58,790,149 (GRCm38)		probably benign	Het
Tpst1	G	T	5: 130,114,502 (GRCm38)	V294F	possibly damaging	Het
Trim23	A	G	13: 104,198,618 (GRCm38)	Y384C	probably damaging	Het
Ube3b	C	G	5: 114,404,617 (GRCm38)	L512V	possibly damaging	Het
Ubxn4	T	A	1: 128,256,179 (GRCm38)	V92E	probably damaging	Het
Vmn2r57	A	T	7: 41,400,643 (GRCm38)	C561S	probably damaging	Het
Vwa8	A	G	14: 78,908,195 (GRCm38)	D104G	probably damaging	Het
Wdr25	T	A	12: 109,026,438 (GRCm38)	L73*	probably null	Het
Wnt9a	G	A	11: 59,330,902 (GRCm38)	A209T	probably benign	Het
Zcchc17	A	C	4: 130,329,595 (GRCm38)	C133G	probably damaging	Het
Zdhhc18	T	A	4: 133,608,676 (GRCm38)	M375L	probably benign	Het
Zfhx3	T	C	8: 108,951,644 (GRCm38)	F3109L	probably benign	Het
Zfp202	T	A	9: 40,210,466 (GRCm38)	D286E	probably benign	Het
Zzef1	T	C	11: 72,893,332 (GRCm38)	L2021P	probably benign	Het

Other mutations in Otogl

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
H8562:Otogl	UTSW	10	107,910,956 (GRCm38)	missense	probably benign	0.00
R0084:Otogl	UTSW	10	107,901,341 (GRCm38)	missense	probably damaging	0.96
R0164:Otogl	UTSW	10	107,874,530 (GRCm38)	missense	probably damaging	0.97
R0164:Otogl	UTSW	10	107,874,530 (GRCm38)	missense	probably damaging	0.97
R0238:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0238:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0239:Otogl	UTSW	10	107,806,696 (GRCm38)	missense	probably damaging	0.98
R0294:Otogl	UTSW	10	107,777,228 (GRCm38)	missense	probably damaging	1.00
R0360:Otogl	UTSW	10	107,770,650 (GRCm38)	splice site	probably benign
R0442:Otogl	UTSW	10	107,876,855 (GRCm38)	missense	probably damaging	1.00
R0488:Otogl	UTSW	10	107,803,605 (GRCm38)	missense	probably benign	0.02
R0507:Otogl	UTSW	10	107,866,740 (GRCm38)	missense	possibly damaging	0.51
R0573:Otogl	UTSW	10	107,780,988 (GRCm38)	missense	probably benign	0.00
R0581:Otogl	UTSW	10	107,789,040 (GRCm38)	missense	possibly damaging	0.79
R0613:Otogl	UTSW	10	107,817,070 (GRCm38)	missense	probably damaging	0.99
R0614:Otogl	UTSW	10	107,798,355 (GRCm38)	missense	probably benign	0.14
R0742:Otogl	UTSW	10	107,866,740 (GRCm38)	missense	possibly damaging	0.51
R0846:Otogl	UTSW	10	107,772,296 (GRCm38)	missense	probably benign	0.40
R1146:Otogl	UTSW	10	107,886,513 (GRCm38)	missense	probably damaging	1.00
R1146:Otogl	UTSW	10	107,886,513 (GRCm38)	missense	probably damaging	1.00
R1439:Otogl	UTSW	10	107,779,252 (GRCm38)	missense	probably benign	0.02
R1457:Otogl	UTSW	10	107,878,152 (GRCm38)	splice site	probably null
R1526:Otogl	UTSW	10	107,869,526 (GRCm38)	missense	probably damaging	1.00
R1662:Otogl	UTSW	10	107,798,357 (GRCm38)	missense	possibly damaging	0.84
R1664:Otogl	UTSW	10	107,806,576 (GRCm38)	missense	probably benign	0.00
R1667:Otogl	UTSW	10	107,813,965 (GRCm38)	nonsense	probably null
R1695:Otogl	UTSW	10	107,814,017 (GRCm38)	missense	probably damaging	0.99
R1731:Otogl	UTSW	10	107,817,111 (GRCm38)	missense	probably damaging	1.00
R1733:Otogl	UTSW	10	107,783,712 (GRCm38)	missense	possibly damaging	0.46
R1824:Otogl	UTSW	10	107,779,831 (GRCm38)	missense	probably benign
R1850:Otogl	UTSW	10	107,878,064 (GRCm38)	missense	probably damaging	1.00
R1856:Otogl	UTSW	10	107,854,264 (GRCm38)	missense	possibly damaging	0.92
R1875:Otogl	UTSW	10	107,899,590 (GRCm38)	missense	probably damaging	1.00
R1938:Otogl	UTSW	10	107,777,575 (GRCm38)	missense	probably damaging	0.98
R1986:Otogl	UTSW	10	107,794,190 (GRCm38)	critical splice acceptor site	probably null
R2072:Otogl	UTSW	10	107,781,043 (GRCm38)	missense	probably damaging	1.00
R2117:Otogl	UTSW	10	107,858,918 (GRCm38)	missense	probably benign	0.06
R2219:Otogl	UTSW	10	107,856,977 (GRCm38)	missense	probably damaging	1.00
R2508:Otogl	UTSW	10	107,874,500 (GRCm38)	missense	probably damaging	0.99
R2883:Otogl	UTSW	10	107,768,981 (GRCm38)	missense	probably damaging	1.00
R2931:Otogl	UTSW	10	107,820,004 (GRCm38)	missense	possibly damaging	0.85
R3620:Otogl	UTSW	10	107,874,371 (GRCm38)	missense	probably damaging	0.99
R3621:Otogl	UTSW	10	107,874,371 (GRCm38)	missense	probably damaging	0.99
R3735:Otogl	UTSW	10	107,899,529 (GRCm38)	nonsense	probably null
R3812:Otogl	UTSW	10	107,899,471 (GRCm38)	missense	probably damaging	1.00
R3880:Otogl	UTSW	10	107,827,704 (GRCm38)	missense	probably damaging	0.96
R3958:Otogl	UTSW	10	107,821,925 (GRCm38)	missense	probably damaging	1.00
R4063:Otogl	UTSW	10	107,790,649 (GRCm38)	missense	probably benign	0.02
R4064:Otogl	UTSW	10	107,790,649 (GRCm38)	missense	probably benign	0.02
R4108:Otogl	UTSW	10	107,771,244 (GRCm38)	missense	probably benign	0.01
R4352:Otogl	UTSW	10	107,869,535 (GRCm38)	missense	probably damaging	1.00
R4526:Otogl	UTSW	10	107,886,980 (GRCm38)	missense	probably damaging	1.00
R4614:Otogl	UTSW	10	107,892,124 (GRCm38)	nonsense	probably null
R4703:Otogl	UTSW	10	107,821,924 (GRCm38)	missense	probably damaging	1.00
R4741:Otogl	UTSW	10	107,779,260 (GRCm38)	missense	probably benign	0.00
R4790:Otogl	UTSW	10	107,822,033 (GRCm38)	critical splice acceptor site	probably null
R4801:Otogl	UTSW	10	107,901,336 (GRCm38)	missense	probably damaging	1.00
R4802:Otogl	UTSW	10	107,901,336 (GRCm38)	missense	probably damaging	1.00
R4910:Otogl	UTSW	10	107,879,517 (GRCm38)	missense	probably benign	0.05
R4913:Otogl	UTSW	10	107,876,855 (GRCm38)	missense	probably damaging	0.98
R5238:Otogl	UTSW	10	107,768,973 (GRCm38)	missense	probably damaging	1.00
R5261:Otogl	UTSW	10	107,777,592 (GRCm38)	missense	probably benign	0.16
R5387:Otogl	UTSW	10	107,780,933 (GRCm38)	missense	probably benign	0.03
R5395:Otogl	UTSW	10	107,817,138 (GRCm38)	missense	probably benign	0.39
R5403:Otogl	UTSW	10	107,808,756 (GRCm38)	missense	probably benign	0.08
R5482:Otogl	UTSW	10	107,821,941 (GRCm38)	missense	probably damaging	0.99
R5547:Otogl	UTSW	10	107,782,048 (GRCm38)	missense	possibly damaging	0.55
R5611:Otogl	UTSW	10	107,786,769 (GRCm38)	missense	probably damaging	1.00
R5642:Otogl	UTSW	10	107,886,552 (GRCm38)	missense	probably benign	0.44
R5690:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5711:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5731:Otogl	UTSW	10	107,881,464 (GRCm38)	missense	probably damaging	0.98
R5743:Otogl	UTSW	10	107,857,001 (GRCm38)	missense	possibly damaging	0.67
R5782:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5820:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R5897:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6004:Otogl	UTSW	10	107,879,529 (GRCm38)	missense	probably damaging	1.00
R6145:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6146:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6147:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6149:Otogl	UTSW	10	107,881,453 (GRCm38)	missense	probably benign	0.36
R6226:Otogl	UTSW	10	107,771,206 (GRCm38)	nonsense	probably null
R6283:Otogl	UTSW	10	107,790,500 (GRCm38)	missense	probably damaging	0.98
R6414:Otogl	UTSW	10	107,782,050 (GRCm38)	missense	probably damaging	1.00
R6604:Otogl	UTSW	10	107,822,034 (GRCm38)	splice site	probably null
R6634:Otogl	UTSW	10	107,862,304 (GRCm38)	missense	probably damaging	1.00
R6727:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6755:Otogl	UTSW	10	107,853,303 (GRCm38)	nonsense	probably null
R6795:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6797:Otogl	UTSW	10	107,777,117 (GRCm38)	synonymous	silent
R6864:Otogl	UTSW	10	107,827,806 (GRCm38)	missense	probably damaging	0.96
R6924:Otogl	UTSW	10	107,808,641 (GRCm38)	missense	probably damaging	1.00
R6967:Otogl	UTSW	10	107,814,050 (GRCm38)	missense	probably benign	0.01
R7000:Otogl	UTSW	10	107,779,831 (GRCm38)	missense	probably benign
R7075:Otogl	UTSW	10	107,778,929 (GRCm38)	missense	probably benign	0.16
R7122:Otogl	UTSW	10	107,866,654 (GRCm38)	missense	probably benign	0.08
R7176:Otogl	UTSW	10	107,778,911 (GRCm38)	missense	probably damaging	1.00
R7184:Otogl	UTSW	10	107,763,200 (GRCm38)	missense	probably damaging	1.00
R7199:Otogl	UTSW	10	107,874,533 (GRCm38)	missense	possibly damaging	0.88
R7252:Otogl	UTSW	10	107,821,943 (GRCm38)	missense	probably benign	0.06
R7286:Otogl	UTSW	10	107,770,610 (GRCm38)	missense	probably benign	0.00
R7373:Otogl	UTSW	10	107,901,251 (GRCm38)	missense	probably damaging	1.00
R7449:Otogl	UTSW	10	107,803,663 (GRCm38)	missense	probably damaging	1.00
R7486:Otogl	UTSW	10	107,821,988 (GRCm38)	missense	probably damaging	1.00
R7493:Otogl	UTSW	10	107,886,982 (GRCm38)	missense	probably benign	0.06
R7659:Otogl	UTSW	10	107,777,120 (GRCm38)	missense	probably benign	0.19
R7732:Otogl	UTSW	10	107,806,664 (GRCm38)	missense	probably benign	0.01
R7754:Otogl	UTSW	10	107,869,546 (GRCm38)	missense	probably damaging	0.99
R7757:Otogl	UTSW	10	107,876,921 (GRCm38)	missense	probably damaging	1.00
R7800:Otogl	UTSW	10	107,886,515 (GRCm38)	missense	probably damaging	0.99
R7864:Otogl	UTSW	10	107,869,567 (GRCm38)	missense	probably damaging	1.00
R7879:Otogl	UTSW	10	107,777,109 (GRCm38)	missense	probably benign	0.00
R7941:Otogl	UTSW	10	107,806,802 (GRCm38)	splice site	probably null
R7956:Otogl	UTSW	10	107,878,026 (GRCm38)	missense	possibly damaging	0.62
R7988:Otogl	UTSW	10	107,895,776 (GRCm38)	missense	probably damaging	1.00
R8057:Otogl	UTSW	10	107,808,615 (GRCm38)	missense	probably benign	0.00
R8058:Otogl	UTSW	10	107,762,426 (GRCm38)	missense	probably damaging	1.00
R8127:Otogl	UTSW	10	107,895,752 (GRCm38)	missense	probably damaging	1.00
R8143:Otogl	UTSW	10	107,806,666 (GRCm38)	missense	probably damaging	1.00
R8310:Otogl	UTSW	10	107,777,600 (GRCm38)	missense	possibly damaging	0.94
R8319:Otogl	UTSW	10	107,853,266 (GRCm38)	critical splice donor site	probably null
R8339:Otogl	UTSW	10	107,789,536 (GRCm38)	missense	probably benign	0.34
R8339:Otogl	UTSW	10	107,789,535 (GRCm38)	missense	probably damaging	0.99
R8394:Otogl	UTSW	10	107,886,465 (GRCm38)	critical splice donor site	probably null
R8428:Otogl	UTSW	10	107,798,736 (GRCm38)	missense	probably damaging	1.00
R8444:Otogl	UTSW	10	107,857,114 (GRCm38)	missense	probably benign	0.01
R8501:Otogl	UTSW	10	107,790,560 (GRCm38)	missense	probably benign
R8503:Otogl	UTSW	10	107,892,126 (GRCm38)	missense	probably damaging	1.00
R8680:Otogl	UTSW	10	107,912,075 (GRCm38)	critical splice donor site	probably null
R9025:Otogl	UTSW	10	107,777,571 (GRCm38)	missense	probably damaging	0.99
R9090:Otogl	UTSW	10	107,817,113 (GRCm38)	missense	probably null	0.99
R9223:Otogl	UTSW	10	107,854,344 (GRCm38)	missense	probably damaging	0.99
R9268:Otogl	UTSW	10	107,781,056 (GRCm38)	missense	probably damaging	1.00
R9271:Otogl	UTSW	10	107,817,113 (GRCm38)	missense	probably null	0.99
R9356:Otogl	UTSW	10	107,782,029 (GRCm38)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,901,295 (GRCm38)	missense	probably damaging	1.00
R9484:Otogl	UTSW	10	107,822,033 (GRCm38)	critical splice acceptor site	probably null
R9571:Otogl	UTSW	10	107,762,503 (GRCm38)	missense	possibly damaging	0.94
R9731:Otogl	UTSW	10	107,899,467 (GRCm38)	missense	probably damaging	1.00
X0065:Otogl	UTSW	10	107,895,782 (GRCm38)	missense	probably damaging	1.00
X0067:Otogl	UTSW	10	107,866,677 (GRCm38)	missense	probably damaging	1.00
Z1176:Otogl	UTSW	10	107,778,873 (GRCm38)	missense	probably damaging	0.97
Z1176:Otogl	UTSW	10	107,777,213 (GRCm38)	missense	probably benign
Z1176:Otogl	UTSW	10	107,789,032 (GRCm38)	missense	probably benign	0.00
Z1177:Otogl	UTSW	10	107,853,397 (GRCm38)	missense	possibly damaging	0.78
Z1177:Otogl	UTSW	10	107,763,258 (GRCm38)	nonsense	probably null
Z1177:Otogl	UTSW	10	107,876,903 (GRCm38)	missense	probably benign	0.14

Predicted Primers

PCR Primer
(F):5'- CCCTGTGCCTAAGATGCCAGTTATC -3'
(R):5'- TGCCTGTGCTGTTGTAGAACATTCC -3'

Sequencing Primer
(F):5'- CTCAGTGGGATGACACTCAATATG -3'
(R):5'- AACCTGGGGACAGTATCACT -3'

Posted On

2014-05-23