Incidental Mutation 'R1752:Chd1'
| ID |
193663 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chd1
|
| Ensembl Gene |
ENSMUSG00000023852 |
| Gene Name |
chromodomain helicase DNA binding protein 1 |
| Synonyms |
4930525N21Rik |
| MMRRC Submission |
039784-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1752 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
15925229-15992872 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 15963494 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000024627]
[ENSMUST00000173311]
|
| AlphaFold |
P40201 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000024627
|
| SMART Domains |
Protein: ENSMUSP00000024627
Gene: ENSMUSG00000023852
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
67 |
N/A |
INTRINSIC |
|
low complexity region
|
105 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
175 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
230 |
N/A |
INTRINSIC |
|
CHROMO
|
268 |
355 |
6.43e-20 |
SMART |
|
CHROMO
|
385 |
443 |
1.19e-14 |
SMART |
|
DEXDc
|
475 |
672 |
3.44e-34 |
SMART |
|
Blast:DEXDc
|
692 |
786 |
2e-54 |
BLAST |
|
low complexity region
|
787 |
799 |
N/A |
INTRINSIC |
|
HELICc
|
816 |
900 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
955 |
1234 |
1e-112 |
BLAST |
|
PDB:4B4C|A
|
1119 |
1320 |
1e-132 |
PDB |
|
low complexity region
|
1325 |
1348 |
N/A |
INTRINSIC |
|
low complexity region
|
1377 |
1388 |
N/A |
INTRINSIC |
|
DUF4208
|
1396 |
1500 |
5.54e-51 |
SMART |
|
low complexity region
|
1507 |
1516 |
N/A |
INTRINSIC |
|
low complexity region
|
1538 |
1549 |
N/A |
INTRINSIC |
|
low complexity region
|
1626 |
1650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000173311
|
| SMART Domains |
Protein: ENSMUSP00000134091
Gene: ENSMUSG00000023852
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
17 |
67 |
N/A |
INTRINSIC |
|
low complexity region
|
105 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
116 |
136 |
N/A |
INTRINSIC |
|
low complexity region
|
151 |
175 |
N/A |
INTRINSIC |
|
low complexity region
|
213 |
230 |
N/A |
INTRINSIC |
|
CHROMO
|
268 |
355 |
6.43e-20 |
SMART |
|
CHROMO
|
385 |
443 |
1.19e-14 |
SMART |
|
DEXDc
|
475 |
672 |
3.44e-34 |
SMART |
|
Blast:DEXDc
|
692 |
786 |
2e-54 |
BLAST |
|
low complexity region
|
787 |
799 |
N/A |
INTRINSIC |
|
HELICc
|
816 |
900 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
955 |
1078 |
2e-38 |
BLAST |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000174461
|
| SMART Domains |
Protein: ENSMUSP00000134718
Gene: ENSMUSG00000023852
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:SNF2_N
|
1 |
148 |
3.6e-34 |
PFAM |
|
low complexity region
|
172 |
184 |
N/A |
INTRINSIC |
|
HELICc
|
201 |
285 |
8.48e-25 |
SMART |
|
Blast:DEXDc
|
340 |
516 |
1e-47 |
BLAST |
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.2%
- 20x: 92.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The CHD family of proteins is characterized by the presence of chromo (chromatin organization modifier) domains and SNF2-related helicase/ATPase domains. CHD genes alter gene expression possibly by modification of chromatin structure thus altering access of the transcriptional apparatus to its chromosomal DNA template. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a knock-out allele exhibit complete embryonic lethality associated with arrest of epiblast development due to increased apoptosis and cell cycle defects, abnormal rostral-caudal axis patterning, and failure to gastrulate. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 90 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca7 |
T |
C |
10: 79,842,468 (GRCm39) |
V1134A |
probably benign |
Het |
| Accsl |
C |
T |
2: 93,688,375 (GRCm39) |
G420S |
probably damaging |
Het |
| Adam29 |
A |
G |
8: 56,325,309 (GRCm39) |
S382P |
probably damaging |
Het |
| Apob |
T |
C |
12: 8,038,766 (GRCm39) |
L393P |
probably benign |
Het |
| Arhgef19 |
T |
G |
4: 140,978,354 (GRCm39) |
S616A |
probably benign |
Het |
| Atp11a |
C |
T |
8: 12,863,094 (GRCm39) |
T91I |
probably damaging |
Het |
| Ccdc88b |
C |
T |
19: 6,830,690 (GRCm39) |
V751I |
probably benign |
Het |
| Ccni |
T |
C |
5: 93,350,315 (GRCm39) |
|
probably benign |
Het |
| Cd2 |
G |
A |
3: 101,183,511 (GRCm39) |
A266V |
probably benign |
Het |
| Cd33 |
T |
C |
7: 43,181,722 (GRCm39) |
D146G |
probably benign |
Het |
| Cdh16 |
A |
G |
8: 105,346,505 (GRCm39) |
|
probably null |
Het |
| Chd5 |
A |
T |
4: 152,459,590 (GRCm39) |
I1109F |
probably damaging |
Het |
| Cir1 |
T |
C |
2: 73,140,882 (GRCm39) |
E29G |
probably damaging |
Het |
| Clec5a |
T |
C |
6: 40,559,187 (GRCm39) |
T66A |
probably damaging |
Het |
| Cpa2 |
A |
G |
6: 30,552,023 (GRCm39) |
D250G |
probably damaging |
Het |
| Crybg2 |
T |
A |
4: 133,800,961 (GRCm39) |
L707H |
probably damaging |
Het |
| Csmd3 |
T |
C |
15: 47,523,669 (GRCm39) |
T2646A |
probably benign |
Het |
| Cul7 |
G |
A |
17: 46,964,093 (GRCm39) |
R390Q |
probably benign |
Het |
| Cyp2c69 |
T |
A |
19: 39,869,597 (GRCm39) |
I141F |
probably damaging |
Het |
| Dapk2 |
C |
G |
9: 66,127,925 (GRCm39) |
R68G |
probably damaging |
Het |
| Dclk2 |
C |
T |
3: 86,713,434 (GRCm39) |
V470I |
possibly damaging |
Het |
| Dixdc1 |
A |
G |
9: 50,593,850 (GRCm39) |
V530A |
probably benign |
Het |
| Dock7 |
A |
G |
4: 98,854,681 (GRCm39) |
F1528L |
probably damaging |
Het |
| Edn1 |
T |
A |
13: 42,457,075 (GRCm39) |
V36E |
possibly damaging |
Het |
| Eng |
T |
C |
2: 32,563,404 (GRCm39) |
V319A |
probably benign |
Het |
| Epb41l2 |
A |
G |
10: 25,336,690 (GRCm39) |
K229E |
probably damaging |
Het |
| Fam184a |
T |
C |
10: 53,550,666 (GRCm39) |
N698S |
probably benign |
Het |
| Fndc7 |
T |
C |
3: 108,776,646 (GRCm39) |
N465S |
probably benign |
Het |
| Fstl4 |
T |
C |
11: 53,077,622 (GRCm39) |
V793A |
probably benign |
Het |
| Gm9797 |
A |
T |
10: 11,485,287 (GRCm39) |
|
noncoding transcript |
Het |
| Hsd17b4 |
T |
C |
18: 50,303,834 (GRCm39) |
S436P |
probably benign |
Het |
| Itsn2 |
T |
G |
12: 4,761,950 (GRCm39) |
|
probably null |
Het |
| Kank3 |
T |
C |
17: 34,038,791 (GRCm39) |
V570A |
probably damaging |
Het |
| Kif13a |
A |
T |
13: 46,951,885 (GRCm39) |
F733Y |
probably damaging |
Het |
| Kif16b |
G |
T |
2: 142,532,586 (GRCm39) |
D1184E |
probably benign |
Het |
| Kif20a |
A |
G |
18: 34,764,634 (GRCm39) |
D727G |
possibly damaging |
Het |
| Kif20b |
T |
A |
19: 34,915,736 (GRCm39) |
S504R |
probably benign |
Het |
| Lrrc37 |
T |
C |
11: 103,505,381 (GRCm39) |
T2196A |
possibly damaging |
Het |
| Ltbp3 |
C |
A |
19: 5,795,685 (GRCm39) |
H180Q |
probably benign |
Het |
| Luzp2 |
T |
C |
7: 54,914,088 (GRCm39) |
S306P |
possibly damaging |
Het |
| Macf1 |
T |
C |
4: 123,377,465 (GRCm39) |
I1490V |
possibly damaging |
Het |
| Manba |
T |
A |
3: 135,212,706 (GRCm39) |
W72R |
probably damaging |
Het |
| Mast1 |
A |
G |
8: 85,651,965 (GRCm39) |
V339A |
probably benign |
Het |
| Mnx1 |
A |
G |
5: 29,682,727 (GRCm39) |
S183P |
unknown |
Het |
| Muc5b |
T |
G |
7: 141,421,488 (GRCm39) |
L4326R |
possibly damaging |
Het |
| Myb |
T |
C |
10: 21,032,336 (GRCm39) |
D15G |
possibly damaging |
Het |
| Ncapg2 |
A |
T |
12: 116,390,338 (GRCm39) |
D429V |
probably damaging |
Het |
| Neurod6 |
A |
G |
6: 55,656,511 (GRCm39) |
V42A |
probably benign |
Het |
| Nfxl1 |
A |
T |
5: 72,698,218 (GRCm39) |
C276S |
probably damaging |
Het |
| Nptx2 |
C |
A |
5: 144,492,171 (GRCm39) |
T316N |
probably damaging |
Het |
| Nrp2 |
T |
A |
1: 62,777,600 (GRCm39) |
F135Y |
probably damaging |
Het |
| Nxpe3 |
A |
T |
16: 55,686,837 (GRCm39) |
F57Y |
probably benign |
Het |
| Or4c109 |
C |
A |
2: 88,817,659 (GRCm39) |
A296S |
possibly damaging |
Het |
| Or51ag1 |
T |
A |
7: 103,155,765 (GRCm39) |
R129S |
probably benign |
Het |
| Osbpl11 |
T |
C |
16: 33,025,205 (GRCm39) |
Y144H |
probably damaging |
Het |
| Pax5 |
T |
C |
4: 44,609,729 (GRCm39) |
Y233C |
probably damaging |
Het |
| Pck1 |
A |
G |
2: 172,998,906 (GRCm39) |
N388S |
probably benign |
Het |
| Plcd3 |
T |
A |
11: 102,971,085 (GRCm39) |
Q157L |
probably benign |
Het |
| Pnma2 |
A |
C |
14: 67,153,785 (GRCm39) |
M70L |
probably benign |
Het |
| Pogk |
T |
C |
1: 166,235,997 (GRCm39) |
K35E |
probably damaging |
Het |
| Ptprb |
T |
A |
10: 116,176,895 (GRCm39) |
V1227E |
probably benign |
Het |
| Pygm |
T |
A |
19: 6,441,064 (GRCm39) |
V450E |
probably damaging |
Het |
| Rb1 |
T |
A |
14: 73,525,064 (GRCm39) |
I190F |
probably damaging |
Het |
| Setd2 |
T |
A |
9: 110,423,673 (GRCm39) |
Y2243N |
probably damaging |
Het |
| Slc11a2 |
A |
T |
15: 100,303,687 (GRCm39) |
L182Q |
probably damaging |
Het |
| Slc45a3 |
T |
C |
1: 131,905,259 (GRCm39) |
L94P |
probably damaging |
Het |
| Slc9a4 |
T |
C |
1: 40,668,421 (GRCm39) |
F688S |
probably benign |
Het |
| Slit3 |
A |
T |
11: 35,455,480 (GRCm39) |
I196F |
probably damaging |
Het |
| Sprn |
G |
A |
7: 139,733,408 (GRCm39) |
|
probably benign |
Het |
| Spsb2 |
A |
G |
6: 124,787,292 (GRCm39) |
D242G |
probably benign |
Het |
| Srpk2 |
A |
G |
5: 23,733,017 (GRCm39) |
I111T |
probably damaging |
Het |
| St8sia4 |
T |
A |
1: 95,519,537 (GRCm39) |
Y317F |
probably benign |
Het |
| Stat5a |
T |
A |
11: 100,774,884 (GRCm39) |
*798K |
probably null |
Het |
| Sult1c2 |
C |
T |
17: 54,271,777 (GRCm39) |
V137M |
possibly damaging |
Het |
| Synj1 |
T |
C |
16: 90,735,361 (GRCm39) |
T1531A |
probably benign |
Het |
| Tasor |
T |
A |
14: 27,193,885 (GRCm39) |
Y1028* |
probably null |
Het |
| Tax1bp1 |
A |
G |
6: 52,698,398 (GRCm39) |
T37A |
probably damaging |
Het |
| Tet1 |
T |
A |
10: 62,648,768 (GRCm39) |
D1888V |
probably damaging |
Het |
| Tln1 |
T |
C |
4: 43,536,311 (GRCm39) |
T1994A |
probably damaging |
Het |
| Tmco3 |
A |
C |
8: 13,341,741 (GRCm39) |
D5A |
probably benign |
Het |
| Tnk1 |
T |
A |
11: 69,747,532 (GRCm39) |
N74I |
possibly damaging |
Het |
| Ttc16 |
A |
T |
2: 32,662,162 (GRCm39) |
S120T |
probably damaging |
Het |
| Ttn |
T |
A |
2: 76,774,448 (GRCm39) |
T2153S |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,594,606 (GRCm39) |
V20480A |
probably damaging |
Het |
| Usp4 |
T |
C |
9: 108,251,441 (GRCm39) |
Y539H |
probably damaging |
Het |
| Zar1 |
A |
C |
5: 72,734,715 (GRCm39) |
V168G |
probably damaging |
Het |
| Zcchc9 |
T |
C |
13: 91,953,899 (GRCm39) |
K119E |
possibly damaging |
Het |
| Zfp251 |
T |
C |
15: 76,737,863 (GRCm39) |
N410S |
possibly damaging |
Het |
| Zfp605 |
A |
T |
5: 110,271,639 (GRCm39) |
D10V |
probably damaging |
Het |
| Zyg11a |
A |
T |
4: 108,062,479 (GRCm39) |
N107K |
possibly damaging |
Het |
|
| Other mutations in Chd1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00704:Chd1
|
APN |
17 |
15,952,827 (GRCm39) |
missense |
probably benign |
0.37 |
|
IGL01356:Chd1
|
APN |
17 |
15,970,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01369:Chd1
|
APN |
17 |
15,975,259 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01519:Chd1
|
APN |
17 |
17,598,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01604:Chd1
|
APN |
17 |
15,990,359 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01635:Chd1
|
APN |
17 |
17,598,858 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01721:Chd1
|
APN |
17 |
15,990,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01959:Chd1
|
APN |
17 |
15,962,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02367:Chd1
|
APN |
17 |
17,610,315 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02476:Chd1
|
APN |
17 |
15,954,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02756:Chd1
|
APN |
17 |
15,951,069 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02817:Chd1
|
APN |
17 |
15,969,762 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03084:Chd1
|
APN |
17 |
15,990,560 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL03108:Chd1
|
APN |
17 |
15,945,543 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
Holly
|
UTSW |
17 |
15,946,545 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R0053:Chd1
|
UTSW |
17 |
15,967,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0053:Chd1
|
UTSW |
17 |
15,967,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0128:Chd1
|
UTSW |
17 |
17,613,829 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0197:Chd1
|
UTSW |
17 |
15,945,693 (GRCm39) |
missense |
probably benign |
|
|
R0285:Chd1
|
UTSW |
17 |
17,594,942 (GRCm39) |
splice site |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,988,830 (GRCm39) |
missense |
probably benign |
|
|
R0326:Chd1
|
UTSW |
17 |
15,988,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0372:Chd1
|
UTSW |
17 |
17,607,552 (GRCm39) |
missense |
probably benign |
0.14 |
|
R0391:Chd1
|
UTSW |
17 |
15,970,156 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0486:Chd1
|
UTSW |
17 |
15,954,604 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0637:Chd1
|
UTSW |
17 |
15,962,550 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R0675:Chd1
|
UTSW |
17 |
15,978,523 (GRCm39) |
unclassified |
probably benign |
|
|
R0701:Chd1
|
UTSW |
17 |
15,945,693 (GRCm39) |
missense |
probably benign |
|
|
R0788:Chd1
|
UTSW |
17 |
15,927,376 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R0848:Chd1
|
UTSW |
17 |
15,990,503 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0883:Chd1
|
UTSW |
17 |
15,945,693 (GRCm39) |
missense |
probably benign |
|
|
R1169:Chd1
|
UTSW |
17 |
15,955,994 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1218:Chd1
|
UTSW |
17 |
15,945,574 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1370:Chd1
|
UTSW |
17 |
17,607,742 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1470:Chd1
|
UTSW |
17 |
15,946,545 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1470:Chd1
|
UTSW |
17 |
15,946,545 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R1478:Chd1
|
UTSW |
17 |
15,959,769 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1759:Chd1
|
UTSW |
17 |
17,607,533 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1767:Chd1
|
UTSW |
17 |
15,990,565 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1938:Chd1
|
UTSW |
17 |
15,982,748 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2007:Chd1
|
UTSW |
17 |
15,951,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2069:Chd1
|
UTSW |
17 |
15,962,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3771:Chd1
|
UTSW |
17 |
17,594,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3773:Chd1
|
UTSW |
17 |
17,594,913 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3849:Chd1
|
UTSW |
17 |
15,952,133 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4241:Chd1
|
UTSW |
17 |
15,990,289 (GRCm39) |
nonsense |
probably null |
|
|
R4242:Chd1
|
UTSW |
17 |
15,990,289 (GRCm39) |
nonsense |
probably null |
|
|
R4354:Chd1
|
UTSW |
17 |
17,610,263 (GRCm39) |
missense |
probably benign |
0.23 |
|
R4468:Chd1
|
UTSW |
17 |
15,980,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4469:Chd1
|
UTSW |
17 |
15,980,657 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4731:Chd1
|
UTSW |
17 |
17,598,079 (GRCm39) |
missense |
probably benign |
0.36 |
|
R4824:Chd1
|
UTSW |
17 |
15,953,386 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4840:Chd1
|
UTSW |
17 |
15,989,016 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4840:Chd1
|
UTSW |
17 |
15,989,015 (GRCm39) |
nonsense |
probably null |
|
|
R4880:Chd1
|
UTSW |
17 |
17,594,916 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4960:Chd1
|
UTSW |
17 |
15,962,493 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5071:Chd1
|
UTSW |
17 |
15,982,667 (GRCm39) |
missense |
probably benign |
|
|
R5078:Chd1
|
UTSW |
17 |
15,946,616 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5114:Chd1
|
UTSW |
17 |
15,948,460 (GRCm39) |
missense |
probably benign |
0.25 |
|
R5268:Chd1
|
UTSW |
17 |
15,956,005 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5304:Chd1
|
UTSW |
17 |
15,990,530 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5304:Chd1
|
UTSW |
17 |
15,975,213 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5307:Chd1
|
UTSW |
17 |
15,952,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5458:Chd1
|
UTSW |
17 |
15,958,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5553:Chd1
|
UTSW |
17 |
17,605,875 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5623:Chd1
|
UTSW |
17 |
15,975,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6022:Chd1
|
UTSW |
17 |
17,598,035 (GRCm39) |
missense |
probably benign |
0.39 |
|
R6137:Chd1
|
UTSW |
17 |
15,978,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6257:Chd1
|
UTSW |
17 |
15,950,465 (GRCm39) |
splice site |
probably null |
|
|
R6373:Chd1
|
UTSW |
17 |
15,958,898 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6458:Chd1
|
UTSW |
17 |
15,950,864 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6476:Chd1
|
UTSW |
17 |
17,601,250 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6508:Chd1
|
UTSW |
17 |
15,958,895 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6553:Chd1
|
UTSW |
17 |
15,945,692 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6745:Chd1
|
UTSW |
17 |
17,607,429 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7107:Chd1
|
UTSW |
17 |
15,981,628 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7230:Chd1
|
UTSW |
17 |
15,927,199 (GRCm39) |
splice site |
probably null |
|
|
R7317:Chd1
|
UTSW |
17 |
15,962,536 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R7341:Chd1
|
UTSW |
17 |
15,990,499 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7421:Chd1
|
UTSW |
17 |
15,969,660 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7704:Chd1
|
UTSW |
17 |
15,987,737 (GRCm39) |
missense |
probably benign |
|
|
R7763:Chd1
|
UTSW |
17 |
15,953,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8156:Chd1
|
UTSW |
17 |
15,981,666 (GRCm39) |
missense |
probably benign |
|
|
R8194:Chd1
|
UTSW |
17 |
17,594,737 (GRCm39) |
start gained |
probably benign |
|
|
R8261:Chd1
|
UTSW |
17 |
17,607,804 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8338:Chd1
|
UTSW |
17 |
15,990,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8401:Chd1
|
UTSW |
17 |
15,963,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8411:Chd1
|
UTSW |
17 |
15,982,711 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9067:Chd1
|
UTSW |
17 |
15,951,107 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R9184:Chd1
|
UTSW |
17 |
15,962,551 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R9210:Chd1
|
UTSW |
17 |
15,950,767 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9212:Chd1
|
UTSW |
17 |
15,950,767 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9666:Chd1
|
UTSW |
17 |
15,955,976 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9673:Chd1
|
UTSW |
17 |
15,989,023 (GRCm39) |
missense |
probably benign |
0.24 |
|
Z1176:Chd1
|
UTSW |
17 |
15,988,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Chd1
|
UTSW |
17 |
15,986,609 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Chd1
|
UTSW |
17 |
15,968,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTTCATTGAGGAGTGAGCATCCCTG -3'
(R):5'- TCCCAAAGCTTGCCCTTCAGAC -3'
Sequencing Primer
(F):5'- GCTCTAGACAGTTTTGAAAGCC -3'
(R):5'- TTAGCACAGAAATACCACTTTAGTCC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation