Incidental Mutation 'R1754:Zfp106'
| ID |
193812 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp106
|
| Ensembl Gene |
ENSMUSG00000027288 |
| Gene Name |
zinc finger protein 106 |
| Synonyms |
Cd-1, H3a, Sh3bp3, sirm |
| MMRRC Submission |
039786-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1754 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
120506820-120563843 bp(-) (GRCm38) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 120533763 bp (GRCm38)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Leucine
at position 721
(S721L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000128995
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000055241]
[ENSMUST00000135625]
[ENSMUST00000171215]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000055241
AA Change: S744L
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000055602
Gene: ENSMUSG00000027288
AA Change: S744L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
ZnF_C2H2
|
43 |
67 |
7.18e1 |
SMART |
|
low complexity region
|
75 |
92 |
N/A |
INTRINSIC |
|
low complexity region
|
141 |
152 |
N/A |
INTRINSIC |
|
low complexity region
|
199 |
212 |
N/A |
INTRINSIC |
|
low complexity region
|
466 |
480 |
N/A |
INTRINSIC |
|
coiled coil region
|
800 |
823 |
N/A |
INTRINSIC |
|
low complexity region
|
842 |
856 |
N/A |
INTRINSIC |
|
low complexity region
|
1049 |
1062 |
N/A |
INTRINSIC |
|
low complexity region
|
1312 |
1321 |
N/A |
INTRINSIC |
|
low complexity region
|
1361 |
1373 |
N/A |
INTRINSIC |
|
low complexity region
|
1389 |
1409 |
N/A |
INTRINSIC |
|
WD40
|
1525 |
1562 |
9.24e-4 |
SMART |
|
WD40
|
1565 |
1607 |
1.83e-7 |
SMART |
|
PQQ
|
1587 |
1618 |
3.42e2 |
SMART |
|
WD40
|
1651 |
1691 |
3.45e-1 |
SMART |
|
PQQ
|
1671 |
1702 |
9.14e1 |
SMART |
|
WD40
|
1694 |
1731 |
2.12e-3 |
SMART |
|
PQQ
|
1711 |
1742 |
6.42e0 |
SMART |
|
WD40
|
1734 |
1771 |
6e-3 |
SMART |
|
PQQ
|
1751 |
1782 |
5.7e2 |
SMART |
|
WD40
|
1774 |
1811 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1818 |
1843 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1851 |
1879 |
1.31e2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000135625
|
| SMART Domains |
Protein: ENSMUSP00000126939
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
5 |
29 |
1.51e0 |
SMART |
|
low complexity region
|
53 |
67 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141874
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000147353
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163384
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000167241
|
| SMART Domains |
Protein: ENSMUSP00000127803
Gene: ENSMUSG00000027288
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
4 |
28 |
1.51e0 |
SMART |
|
low complexity region
|
74 |
85 |
N/A |
INTRINSIC |
|
low complexity region
|
132 |
145 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000171215
AA Change: S721L
PolyPhen 2
Score 0.960 (Sensitivity: 0.78; Specificity: 0.95)
|
| SMART Domains |
Protein: ENSMUSP00000128995
Gene: ENSMUSG00000027288
AA Change: S721L
| Domain | Start | End | E-Value | Type |
|---|
|
ZnF_C2H2
|
20 |
44 |
7.18e1 |
SMART |
|
low complexity region
|
52 |
69 |
N/A |
INTRINSIC |
|
low complexity region
|
118 |
129 |
N/A |
INTRINSIC |
|
low complexity region
|
176 |
189 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
coiled coil region
|
777 |
800 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
833 |
N/A |
INTRINSIC |
|
low complexity region
|
1026 |
1039 |
N/A |
INTRINSIC |
|
low complexity region
|
1289 |
1298 |
N/A |
INTRINSIC |
|
low complexity region
|
1338 |
1350 |
N/A |
INTRINSIC |
|
low complexity region
|
1366 |
1386 |
N/A |
INTRINSIC |
|
WD40
|
1502 |
1539 |
9.24e-4 |
SMART |
|
WD40
|
1542 |
1584 |
1.83e-7 |
SMART |
|
PQQ
|
1564 |
1595 |
3.42e2 |
SMART |
|
WD40
|
1628 |
1668 |
3.45e-1 |
SMART |
|
PQQ
|
1648 |
1679 |
9.14e1 |
SMART |
|
WD40
|
1671 |
1708 |
2.12e-3 |
SMART |
|
PQQ
|
1688 |
1719 |
6.42e0 |
SMART |
|
WD40
|
1711 |
1748 |
6e-3 |
SMART |
|
PQQ
|
1728 |
1759 |
5.7e2 |
SMART |
|
WD40
|
1751 |
1788 |
3.58e-1 |
SMART |
|
ZnF_C2H2
|
1795 |
1820 |
5.34e-1 |
SMART |
|
ZnF_C2H2
|
1828 |
1856 |
1.31e2 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000181963
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a null allele exhibit an abnormal gait, progressive motor deficits, kyphosis, weight loss, severe adult-onset degenerative sensory-motor axonopathy, mitochondrial dysfunction, and premature death. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 86 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930563D23Rik |
A |
G |
16: 92,321,031 (GRCm38) |
V123A |
probably damaging |
Het |
| Abca2 |
T |
A |
2: 25,434,333 (GRCm38) |
L234M |
probably benign |
Het |
| Abca3 |
G |
A |
17: 24,377,779 (GRCm38) |
S402N |
probably benign |
Het |
| Acad12 |
A |
T |
5: 121,607,481 (GRCm38) |
V249D |
probably benign |
Het |
| Acp4 |
T |
C |
7: 44,255,004 (GRCm38) |
I212V |
probably benign |
Het |
| Actl6a |
T |
A |
3: 32,718,574 (GRCm38) |
V233D |
probably damaging |
Het |
| Aire |
T |
A |
10: 78,030,290 (GRCm38) |
Q533L |
probably damaging |
Het |
| Aldh3b3 |
T |
C |
19: 3,968,517 (GRCm38) |
S411P |
probably benign |
Het |
| Amer2 |
A |
G |
14: 60,379,757 (GRCm38) |
K467R |
probably damaging |
Het |
| Apol9b |
A |
T |
15: 77,735,762 (GRCm38) |
I253F |
probably benign |
Het |
| Arid1b |
A |
G |
17: 5,279,201 (GRCm38) |
|
probably null |
Het |
| Atp6v0a4 |
T |
C |
6: 38,067,829 (GRCm38) |
T494A |
probably benign |
Het |
| Atp6v1b2 |
A |
G |
8: 69,101,961 (GRCm38) |
D106G |
probably benign |
Het |
| Avpr1b |
T |
C |
1: 131,600,101 (GRCm38) |
S121P |
probably damaging |
Het |
| Bcl11a |
A |
C |
11: 24,164,724 (GRCm38) |
E689A |
probably damaging |
Het |
| Brpf3 |
T |
G |
17: 28,821,323 (GRCm38) |
L906R |
probably benign |
Het |
| Btn1a1 |
T |
C |
13: 23,460,468 (GRCm38) |
K287E |
probably benign |
Het |
| Cacna1i |
A |
G |
15: 80,371,529 (GRCm38) |
H871R |
probably damaging |
Het |
| Cd14 |
A |
T |
18: 36,725,514 (GRCm38) |
L296Q |
probably damaging |
Het |
| Col1a2 |
G |
A |
6: 4,518,822 (GRCm38) |
|
probably benign |
Het |
| Colgalt1 |
G |
T |
8: 71,623,179 (GRCm38) |
W490L |
probably damaging |
Het |
| Ctnna2 |
A |
G |
6: 77,636,749 (GRCm38) |
I273T |
possibly damaging |
Het |
| Dnah7a |
A |
T |
1: 53,504,185 (GRCm38) |
D2275E |
probably benign |
Het |
| Dnah7a |
A |
C |
1: 53,561,900 (GRCm38) |
|
probably null |
Het |
| Egfem1 |
T |
C |
3: 29,668,333 (GRCm38) |
Y404H |
possibly damaging |
Het |
| Esm1 |
A |
T |
13: 113,216,696 (GRCm38) |
N171Y |
probably damaging |
Het |
| Exoc1 |
T |
G |
5: 76,560,322 (GRCm38) |
|
probably null |
Het |
| Fcho1 |
A |
G |
8: 71,711,246 (GRCm38) |
I580T |
probably benign |
Het |
| Fgfr1 |
A |
G |
8: 25,570,210 (GRCm38) |
H552R |
probably damaging |
Het |
| Fsbp |
A |
G |
4: 11,583,906 (GRCm38) |
R202G |
probably damaging |
Het |
| Gabra6 |
A |
G |
11: 42,316,561 (GRCm38) |
V231A |
probably damaging |
Het |
| Gm8765 |
A |
T |
13: 50,701,087 (GRCm38) |
T254S |
probably damaging |
Het |
| Gmeb1 |
A |
G |
4: 132,232,027 (GRCm38) |
S239P |
probably benign |
Het |
| Gnpat |
T |
A |
8: 124,877,006 (GRCm38) |
Y208N |
probably damaging |
Het |
| Il21 |
T |
C |
3: 37,225,525 (GRCm38) |
K114R |
possibly damaging |
Het |
| Inhbc |
T |
C |
10: 127,370,293 (GRCm38) |
D35G |
possibly damaging |
Het |
| Inpp4b |
A |
T |
8: 81,770,811 (GRCm38) |
T87S |
probably damaging |
Het |
| Kcns2 |
T |
C |
15: 34,839,517 (GRCm38) |
I342T |
possibly damaging |
Het |
| Ky |
A |
T |
9: 102,541,927 (GRCm38) |
T378S |
possibly damaging |
Het |
| Lcat |
CAT |
C |
8: 105,941,814 (GRCm38) |
|
probably null |
Het |
| Lrrc8d |
T |
C |
5: 105,812,657 (GRCm38) |
V311A |
probably benign |
Het |
| Mief1 |
A |
G |
15: 80,249,602 (GRCm38) |
I287V |
probably damaging |
Het |
| Mrpl47 |
A |
G |
3: 32,730,084 (GRCm38) |
V179A |
probably benign |
Het |
| Mtcl1 |
T |
C |
17: 66,380,183 (GRCm38) |
K576R |
probably damaging |
Het |
| Myh10 |
C |
A |
11: 68,813,058 (GRCm38) |
A1902E |
probably damaging |
Het |
| Nlrp3 |
A |
G |
11: 59,558,402 (GRCm38) |
T837A |
possibly damaging |
Het |
| Nr1i3 |
T |
C |
1: 171,217,394 (GRCm38) |
Y132H |
probably damaging |
Het |
| Oit3 |
T |
C |
10: 59,427,940 (GRCm38) |
|
probably null |
Het |
| Olfr1186 |
A |
T |
2: 88,525,815 (GRCm38) |
R77S |
probably damaging |
Het |
| Olfr1467 |
T |
C |
19: 13,365,353 (GRCm38) |
S242P |
probably damaging |
Het |
| Olfr193 |
T |
A |
16: 59,110,581 (GRCm38) |
I10F |
probably benign |
Het |
| Olfr30 |
A |
T |
11: 58,455,262 (GRCm38) |
M229K |
probably damaging |
Het |
| Olfr427 |
A |
G |
1: 174,100,033 (GRCm38) |
T192A |
probably benign |
Het |
| Olfr533 |
A |
T |
7: 140,466,860 (GRCm38) |
I220F |
probably damaging |
Het |
| Olfr8 |
T |
A |
10: 78,955,697 (GRCm38) |
V164E |
probably damaging |
Het |
| Olfr825 |
G |
A |
10: 130,163,164 (GRCm38) |
T54I |
probably benign |
Het |
| Pdlim4 |
T |
C |
11: 54,055,873 (GRCm38) |
E196G |
possibly damaging |
Het |
| Pigs |
A |
G |
11: 78,337,847 (GRCm38) |
Y293C |
probably damaging |
Het |
| Pkd1l2 |
A |
T |
8: 117,030,719 (GRCm38) |
S1527T |
possibly damaging |
Het |
| Pkd2l1 |
A |
T |
19: 44,155,601 (GRCm38) |
Y344* |
probably null |
Het |
| Pmp2 |
T |
C |
3: 10,182,224 (GRCm38) |
|
probably null |
Het |
| Polr3e |
T |
C |
7: 120,939,298 (GRCm38) |
|
probably null |
Het |
| Ppp3ca |
C |
G |
3: 136,881,448 (GRCm38) |
I230M |
probably benign |
Het |
| Ppp5c |
T |
C |
7: 17,005,310 (GRCm38) |
H463R |
probably benign |
Het |
| Ptger1 |
A |
G |
8: 83,669,297 (GRCm38) |
N328D |
probably benign |
Het |
| Rhno1 |
A |
T |
6: 128,357,859 (GRCm38) |
I167N |
probably benign |
Het |
| Rictor |
C |
A |
15: 6,735,368 (GRCm38) |
P34H |
probably damaging |
Het |
| Rnf10 |
A |
C |
5: 115,245,865 (GRCm38) |
S630R |
probably damaging |
Het |
| Rnf168 |
A |
G |
16: 32,299,124 (GRCm38) |
Q501R |
probably benign |
Het |
| Rngtt |
T |
G |
4: 33,329,634 (GRCm38) |
|
probably null |
Het |
| Samd9l |
G |
T |
6: 3,373,126 (GRCm38) |
F1378L |
probably damaging |
Het |
| Slc9c1 |
T |
A |
16: 45,589,509 (GRCm38) |
M864K |
probably benign |
Het |
| Slitrk5 |
T |
C |
14: 111,680,519 (GRCm38) |
F525S |
probably damaging |
Het |
| Sox6 |
T |
C |
7: 115,477,055 (GRCm38) |
M784V |
probably benign |
Het |
| Spint2 |
C |
T |
7: 29,260,366 (GRCm38) |
|
probably null |
Het |
| Ssh1 |
A |
T |
5: 113,955,845 (GRCm38) |
I276N |
probably damaging |
Het |
| Trank1 |
T |
A |
9: 111,392,871 (GRCm38) |
V2892D |
probably benign |
Het |
| Ttn |
C |
A |
2: 76,751,040 (GRCm38) |
E21424* |
probably null |
Het |
| Usp17lc |
T |
C |
7: 103,418,848 (GRCm38) |
I450T |
probably benign |
Het |
| Vcan |
A |
G |
13: 89,704,735 (GRCm38) |
V702A |
probably benign |
Het |
| Vmn1r36 |
TA |
TAA |
6: 66,716,533 (GRCm38) |
|
probably null |
Het |
| Vmn2r51 |
G |
T |
7: 10,099,946 (GRCm38) |
D388E |
probably benign |
Het |
| Zfp189 |
T |
A |
4: 49,529,342 (GRCm38) |
H148Q |
possibly damaging |
Het |
| Zfp352 |
A |
T |
4: 90,223,809 (GRCm38) |
Y62F |
probably benign |
Het |
| Zfp839 |
T |
C |
12: 110,855,457 (GRCm38) |
V235A |
probably damaging |
Het |
| Zfp871 |
T |
C |
17: 32,775,334 (GRCm38) |
Y289C |
probably damaging |
Het |
|
| Other mutations in Zfp106 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00330:Zfp106
|
APN |
2 |
120,539,497 (GRCm38) |
missense |
probably benign |
0.45 |
|
IGL00816:Zfp106
|
APN |
2 |
120,526,848 (GRCm38) |
missense |
probably benign |
0.02 |
|
IGL00822:Zfp106
|
APN |
2 |
120,514,160 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL00848:Zfp106
|
APN |
2 |
120,512,727 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01293:Zfp106
|
APN |
2 |
120,535,035 (GRCm38) |
missense |
possibly damaging |
0.92 |
|
IGL01323:Zfp106
|
APN |
2 |
120,524,464 (GRCm38) |
missense |
possibly damaging |
0.74 |
|
IGL01662:Zfp106
|
APN |
2 |
120,523,553 (GRCm38) |
missense |
probably benign |
0.17 |
|
IGL01683:Zfp106
|
APN |
2 |
120,524,555 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL01809:Zfp106
|
APN |
2 |
120,533,671 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL01958:Zfp106
|
APN |
2 |
120,534,807 (GRCm38) |
missense |
probably benign |
0.26 |
|
IGL01960:Zfp106
|
APN |
2 |
120,539,322 (GRCm38) |
missense |
probably benign |
0.08 |
|
IGL01960:Zfp106
|
APN |
2 |
120,524,043 (GRCm38) |
missense |
probably damaging |
0.99 |
|
IGL02168:Zfp106
|
APN |
2 |
120,534,231 (GRCm38) |
missense |
possibly damaging |
0.90 |
|
IGL02623:Zfp106
|
APN |
2 |
120,545,914 (GRCm38) |
splice site |
probably null |
|
|
IGL02798:Zfp106
|
APN |
2 |
120,510,510 (GRCm38) |
missense |
probably damaging |
1.00 |
|
IGL02828:Zfp106
|
APN |
2 |
120,531,697 (GRCm38) |
missense |
possibly damaging |
0.86 |
|
IGL03022:Zfp106
|
APN |
2 |
120,528,639 (GRCm38) |
splice site |
probably benign |
|
|
IGL03308:Zfp106
|
APN |
2 |
120,524,024 (GRCm38) |
missense |
probably benign |
0.00 |
|
IGL03324:Zfp106
|
APN |
2 |
120,535,387 (GRCm38) |
missense |
probably benign |
0.01 |
|
lepton
|
UTSW |
2 |
120,532,104 (GRCm38) |
missense |
probably damaging |
0.98 |
|
Proton
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
quark
|
UTSW |
2 |
120,535,060 (GRCm38) |
nonsense |
probably null |
|
|
R0040_zfp106_031
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
string
|
UTSW |
2 |
120,533,594 (GRCm38) |
missense |
probably damaging |
0.96 |
|
theory
|
UTSW |
2 |
120,533,677 (GRCm38) |
nonsense |
probably null |
|
|
R0040:Zfp106
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0040:Zfp106
|
UTSW |
2 |
120,531,613 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0135:Zfp106
|
UTSW |
2 |
120,520,487 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0180:Zfp106
|
UTSW |
2 |
120,533,875 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R0387:Zfp106
|
UTSW |
2 |
120,528,472 (GRCm38) |
splice site |
probably null |
|
|
R0558:Zfp106
|
UTSW |
2 |
120,532,196 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0680:Zfp106
|
UTSW |
2 |
120,527,016 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R0729:Zfp106
|
UTSW |
2 |
120,555,248 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R0828:Zfp106
|
UTSW |
2 |
120,535,603 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1124:Zfp106
|
UTSW |
2 |
120,534,714 (GRCm38) |
missense |
probably benign |
0.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,520,536 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1147:Zfp106
|
UTSW |
2 |
120,520,536 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1226:Zfp106
|
UTSW |
2 |
120,524,079 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1239:Zfp106
|
UTSW |
2 |
120,533,594 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R1634:Zfp106
|
UTSW |
2 |
120,533,677 (GRCm38) |
nonsense |
probably null |
|
|
R1754:Zfp106
|
UTSW |
2 |
120,533,764 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R1755:Zfp106
|
UTSW |
2 |
120,535,175 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R1763:Zfp106
|
UTSW |
2 |
120,520,428 (GRCm38) |
missense |
probably benign |
0.03 |
|
R1875:Zfp106
|
UTSW |
2 |
120,513,615 (GRCm38) |
critical splice donor site |
probably null |
|
|
R1903:Zfp106
|
UTSW |
2 |
120,526,848 (GRCm38) |
missense |
probably benign |
0.02 |
|
R1932:Zfp106
|
UTSW |
2 |
120,531,681 (GRCm38) |
missense |
possibly damaging |
0.80 |
|
R2070:Zfp106
|
UTSW |
2 |
120,523,529 (GRCm38) |
missense |
probably benign |
0.11 |
|
R2301:Zfp106
|
UTSW |
2 |
120,535,650 (GRCm38) |
missense |
probably benign |
0.04 |
|
R3429:Zfp106
|
UTSW |
2 |
120,527,063 (GRCm38) |
missense |
probably benign |
0.00 |
|
R3720:Zfp106
|
UTSW |
2 |
120,534,599 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3875:Zfp106
|
UTSW |
2 |
120,534,613 (GRCm38) |
missense |
probably benign |
0.08 |
|
R3881:Zfp106
|
UTSW |
2 |
120,532,149 (GRCm38) |
missense |
probably benign |
0.01 |
|
R3921:Zfp106
|
UTSW |
2 |
120,533,616 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R3923:Zfp106
|
UTSW |
2 |
120,534,856 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R4087:Zfp106
|
UTSW |
2 |
120,526,899 (GRCm38) |
splice site |
probably null |
|
|
R4678:Zfp106
|
UTSW |
2 |
120,533,740 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R4965:Zfp106
|
UTSW |
2 |
120,533,919 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R5011:Zfp106
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5013:Zfp106
|
UTSW |
2 |
120,510,534 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R5151:Zfp106
|
UTSW |
2 |
120,534,727 (GRCm38) |
missense |
probably benign |
0.01 |
|
R5227:Zfp106
|
UTSW |
2 |
120,523,968 (GRCm38) |
missense |
probably benign |
0.11 |
|
R5328:Zfp106
|
UTSW |
2 |
120,520,417 (GRCm38) |
missense |
possibly damaging |
0.73 |
|
R5403:Zfp106
|
UTSW |
2 |
120,534,781 (GRCm38) |
missense |
probably benign |
0.02 |
|
R5624:Zfp106
|
UTSW |
2 |
120,531,957 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5686:Zfp106
|
UTSW |
2 |
120,533,507 (GRCm38) |
splice site |
probably null |
|
|
R5691:Zfp106
|
UTSW |
2 |
120,524,471 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R5852:Zfp106
|
UTSW |
2 |
120,516,006 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,535,393 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6032:Zfp106
|
UTSW |
2 |
120,535,393 (GRCm38) |
missense |
probably benign |
0.00 |
|
R6298:Zfp106
|
UTSW |
2 |
120,522,704 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R6409:Zfp106
|
UTSW |
2 |
120,532,104 (GRCm38) |
missense |
probably damaging |
0.98 |
|
R6505:Zfp106
|
UTSW |
2 |
120,534,502 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R6598:Zfp106
|
UTSW |
2 |
120,535,060 (GRCm38) |
nonsense |
probably null |
|
|
R6765:Zfp106
|
UTSW |
2 |
120,539,454 (GRCm38) |
missense |
probably damaging |
0.96 |
|
R7013:Zfp106
|
UTSW |
2 |
120,531,632 (GRCm38) |
missense |
probably damaging |
0.99 |
|
R7453:Zfp106
|
UTSW |
2 |
120,545,919 (GRCm38) |
splice site |
probably null |
|
|
R7453:Zfp106
|
UTSW |
2 |
120,510,527 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R7643:Zfp106
|
UTSW |
2 |
120,512,734 (GRCm38) |
missense |
probably benign |
0.01 |
|
R7829:Zfp106
|
UTSW |
2 |
120,524,057 (GRCm38) |
missense |
possibly damaging |
0.94 |
|
R7897:Zfp106
|
UTSW |
2 |
120,535,615 (GRCm38) |
nonsense |
probably null |
|
|
R7909:Zfp106
|
UTSW |
2 |
120,514,219 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8054:Zfp106
|
UTSW |
2 |
120,524,519 (GRCm38) |
missense |
possibly damaging |
0.93 |
|
R8124:Zfp106
|
UTSW |
2 |
120,524,331 (GRCm38) |
missense |
probably benign |
0.44 |
|
R8203:Zfp106
|
UTSW |
2 |
120,519,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R8350:Zfp106
|
UTSW |
2 |
120,535,618 (GRCm38) |
missense |
|
|
|
R8450:Zfp106
|
UTSW |
2 |
120,535,618 (GRCm38) |
missense |
|
|
|
R8698:Zfp106
|
UTSW |
2 |
120,524,119 (GRCm38) |
critical splice donor site |
probably null |
|
|
R8985:Zfp106
|
UTSW |
2 |
120,535,596 (GRCm38) |
missense |
|
|
|
R9015:Zfp106
|
UTSW |
2 |
120,533,538 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9036:Zfp106
|
UTSW |
2 |
120,539,425 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9142:Zfp106
|
UTSW |
2 |
120,520,454 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9154:Zfp106
|
UTSW |
2 |
120,534,331 (GRCm38) |
nonsense |
probably null |
|
|
R9175:Zfp106
|
UTSW |
2 |
120,522,716 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9529:Zfp106
|
UTSW |
2 |
120,520,526 (GRCm38) |
missense |
probably damaging |
0.97 |
|
R9572:Zfp106
|
UTSW |
2 |
120,519,078 (GRCm38) |
missense |
probably damaging |
1.00 |
|
R9581:Zfp106
|
UTSW |
2 |
120,535,326 (GRCm38) |
missense |
|
|
|
RF008:Zfp106
|
UTSW |
2 |
120,524,545 (GRCm38) |
small deletion |
probably benign |
|
|
RF025:Zfp106
|
UTSW |
2 |
120,524,545 (GRCm38) |
small deletion |
probably benign |
|
|
X0025:Zfp106
|
UTSW |
2 |
120,534,816 (GRCm38) |
missense |
probably benign |
|
|
Z1088:Zfp106
|
UTSW |
2 |
120,530,490 (GRCm38) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTTGCTGAATGACCTGTTCCCAG -3'
(R):5'- CACAGTTCTCCAGAAAGAGGCTGAG -3'
Sequencing Primer
(F):5'- AGTTGACATTTCTCCTTGATGC -3'
(R):5'- GGCTTACTGCTAAACTTGAAGACC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation