Mutagenetix > Incidental Mutation

Incidental Mutation 'R0035:Dnah8'

19440

Institutional Source

Beutler Lab

Gene Symbol

Dnah8

Ensembl Gene

ENSMUSG00000033826

Gene Name

dynein, axonemal, heavy chain 8

Synonyms

P1-Loop, Dnahc8, Hst6.7b

MMRRC Submission

038329-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.477) question?

Stock #

R0035 (G1)

Quality Score

177

Status

Validated

Chromosome

Chromosomal Location

30845909-31094736 bp(+) (GRCm39)

Type of Mutation

splice site

DNA Base Change (assembly)

A to T at 30902595 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000127878 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000170651]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000170651

SMART Domains

Protein: ENSMUSP00000127878
Gene: ENSMUSG00000033826

Domain	Start	End	E-Value	Type
low complexity region	2	54	N/A	INTRINSIC
Pfam:DHC_N1	379	936	8.4e-159	PFAM
low complexity region	1069	1080	N/A	INTRINSIC
low complexity region	1224	1237	N/A	INTRINSIC
Pfam:DHC_N2	1509	1917	1.6e-134	PFAM
AAA	2082	2226	1.38e-1	SMART
AAA	2363	2516	2.04e-1	SMART
AAA	2689	2837	8.15e-2	SMART
Pfam:AAA_8	3022	3294	4e-72	PFAM
Pfam:MT	3306	3656	3.6e-48	PFAM
Pfam:AAA_9	3676	3901	6.7e-85	PFAM
Pfam:Dynein_heavy	4039	4728	8.4e-250	PFAM

Meta Mutation Damage Score

0.0898

Coding Region Coverage

1x: 99.1%
3x: 97.8%
10x: 94.7%
20x: 87.1%

Validation Efficiency

99% (70/71)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a heavy chain of an axonemal dynein involved in sperm and respiratory cilia motility. Axonemal dyneins generate force through hydrolysis of ATP and binding to microtubules. [provided by RefSeq, Jan 2012]

Allele List at MGI

Other mutations in this stock

Total: 65 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
3110040N11Rik	T	C	7: 81,438,297 (GRCm39)	T20A	probably benign	Het
Aadacl4	A	G	4: 144,344,511 (GRCm39)	T96A	probably damaging	Het
Abcb6	A	G	1: 75,151,651 (GRCm39)	V473A	possibly damaging	Het
Abo	C	A	2: 26,733,385 (GRCm39)	K273N	possibly damaging	Het
Acvr1c	A	G	2: 58,205,791 (GRCm39)		probably benign	Het
Adcy8	A	T	15: 64,571,217 (GRCm39)	V1142D	probably benign	Het
Akna	T	A	4: 63,300,682 (GRCm39)	H591L	probably benign	Het
Aox1	T	C	1: 58,393,581 (GRCm39)	V1247A	probably benign	Het
Ap4b1	T	C	3: 103,727,980 (GRCm39)		probably benign	Het
Armh3	A	T	19: 45,879,679 (GRCm39)	M558K	probably damaging	Het
Atm	A	G	9: 53,424,480 (GRCm39)	V607A	probably benign	Het
Bltp1	T	A	3: 37,041,747 (GRCm39)	Y2708*	probably null	Het
Cass4	C	T	2: 172,258,412 (GRCm39)	P137S	probably damaging	Het
Cfap53	A	G	18: 74,433,278 (GRCm39)	E121G	probably damaging	Het
Chmp6	T	C	11: 119,807,508 (GRCm39)	V31A	probably damaging	Het
Clec4a3	T	A	6: 122,944,508 (GRCm39)	Y185N	probably damaging	Het
Clic5	A	G	17: 44,586,200 (GRCm39)	T230A	probably damaging	Het
Clspn	G	T	4: 126,458,796 (GRCm39)		probably null	Het
Cntn1	T	A	15: 92,129,969 (GRCm39)		probably benign	Het
Col4a3	G	A	1: 82,650,474 (GRCm39)	G577R	unknown	Het
Defa21	T	A	8: 21,515,784 (GRCm39)		probably null	Het
Deup1	T	C	9: 15,511,117 (GRCm39)	R221G	possibly damaging	Het
Dnase1l2	A	G	17: 24,660,049 (GRCm39)	V273A	probably damaging	Het
Gm5134	T	A	10: 75,829,698 (GRCm39)	F328Y	probably benign	Het
Golph3	A	T	15: 12,339,776 (GRCm39)	E96D	probably damaging	Het
Hspd1	A	G	1: 55,122,942 (GRCm39)	V151A	probably benign	Het
Htr1f	A	C	16: 64,746,860 (GRCm39)	I144S	probably damaging	Het
Il23r	A	G	6: 67,450,772 (GRCm39)		probably benign	Het
Il25	A	G	14: 55,170,553 (GRCm39)	E42G	probably damaging	Het
Il36b	A	T	2: 24,049,890 (GRCm39)	H167L	probably benign	Het
Klrb1-ps1	C	T	6: 129,106,306 (GRCm39)	A149V	possibly damaging	Het
Kmt2e	T	A	5: 23,690,619 (GRCm39)		probably benign	Het
Ktn1	A	G	14: 47,967,836 (GRCm39)	N1167D	probably benign	Het
Lama4	T	A	10: 38,948,734 (GRCm39)	D832E	probably benign	Het
Map1b	A	G	13: 99,571,846 (GRCm39)	S292P	probably damaging	Het
Map6	C	T	7: 98,966,815 (GRCm39)	T345I	probably damaging	Het
Mark2	A	T	19: 7,262,017 (GRCm39)		probably benign	Het
Me3	C	A	7: 89,500,967 (GRCm39)	H559Q	probably benign	Het
Myo1b	A	G	1: 51,817,541 (GRCm39)	F574L	probably damaging	Het
Nos2	T	C	11: 78,836,553 (GRCm39)	S431P	probably damaging	Het
Nr1h5	T	A	3: 102,856,889 (GRCm39)	K208*	probably null	Het
Nup214	T	C	2: 31,880,379 (GRCm39)		probably null	Het
Obp2b	T	C	2: 25,628,645 (GRCm39)	L133P	probably damaging	Het
Or14a259	T	C	7: 86,013,395 (GRCm39)	D50G	possibly damaging	Het
Or5k1	A	T	16: 58,617,485 (GRCm39)	C241*	probably null	Het
Osbp2	C	T	11: 3,667,997 (GRCm39)		probably benign	Het
Ptafr	C	A	4: 132,306,864 (GRCm39)	L85I	probably benign	Het
Ptprk	T	A	10: 28,139,504 (GRCm39)	Y76*	probably null	Het
Rad50	A	G	11: 53,545,854 (GRCm39)		probably benign	Het
Rasef	G	T	4: 73,681,091 (GRCm39)		probably benign	Het
Slitrk6	A	T	14: 110,987,364 (GRCm39)	L781H	probably damaging	Het
Tbc1d1	T	A	5: 64,414,080 (GRCm39)	I18N	probably damaging	Het
Tbc1d17	T	C	7: 44,490,832 (GRCm39)	N587D	probably benign	Het
Trank1	A	T	9: 111,195,844 (GRCm39)	K1289N	probably benign	Het
Tspyl3	A	G	2: 153,066,240 (GRCm39)	S333P	probably damaging	Het
Ush2a	G	A	1: 188,089,085 (GRCm39)	V347I	probably benign	Het
Usp17le	G	T	7: 104,418,269 (GRCm39)	S291*	probably null	Het
Usp24	T	A	4: 106,225,224 (GRCm39)	S619T	probably benign	Het
Vmn2r10	T	C	5: 109,145,467 (GRCm39)		probably benign	Het
Vmn2r78	A	G	7: 86,569,413 (GRCm39)	E102G	probably benign	Het
Vwa3b	G	A	1: 37,204,770 (GRCm39)	V85I	possibly damaging	Het
Wwp1	A	C	4: 19,631,116 (GRCm39)	I639R	probably damaging	Het
Xpo5	A	G	17: 46,551,101 (GRCm39)	T1001A	probably benign	Het
Zc3h12c	A	T	9: 52,055,047 (GRCm39)	M235K	probably benign	Het
Zfp619	G	A	7: 39,186,706 (GRCm39)	G912D	probably damaging	Het

Other mutations in Dnah8

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00498:Dnah8	APN	17	30,896,150 (GRCm39)	missense	probably benign	0.06
IGL00508:Dnah8	APN	17	31,074,904 (GRCm39)	missense	probably damaging	1.00
IGL00547:Dnah8	APN	17	31,034,677 (GRCm39)	nonsense	probably null
IGL00551:Dnah8	APN	17	30,882,452 (GRCm39)	nonsense	probably null
IGL00732:Dnah8	APN	17	30,875,615 (GRCm39)	missense	probably damaging	1.00
IGL00775:Dnah8	APN	17	30,986,880 (GRCm39)	nonsense	probably null
IGL00840:Dnah8	APN	17	31,009,915 (GRCm39)	missense	probably damaging	1.00
IGL00845:Dnah8	APN	17	31,038,250 (GRCm39)	critical splice donor site	probably null
IGL00953:Dnah8	APN	17	30,925,431 (GRCm39)	nonsense	probably null
IGL00976:Dnah8	APN	17	31,070,684 (GRCm39)	missense	probably damaging	0.98
IGL01395:Dnah8	APN	17	30,854,979 (GRCm39)	missense	probably benign	0.06
IGL01467:Dnah8	APN	17	30,998,890 (GRCm39)	missense	probably damaging	1.00
IGL01469:Dnah8	APN	17	30,902,688 (GRCm39)	splice site	probably benign
IGL01515:Dnah8	APN	17	30,867,459 (GRCm39)	missense	probably benign
IGL01723:Dnah8	APN	17	30,927,445 (GRCm39)	missense	probably damaging	1.00
IGL01837:Dnah8	APN	17	30,970,565 (GRCm39)	critical splice donor site	probably null
IGL01921:Dnah8	APN	17	30,955,115 (GRCm39)	missense	probably benign
IGL01958:Dnah8	APN	17	31,074,869 (GRCm39)	splice site	probably benign
IGL01968:Dnah8	APN	17	30,875,572 (GRCm39)	nonsense	probably null
IGL02093:Dnah8	APN	17	30,936,854 (GRCm39)	missense	probably damaging	0.99
IGL02151:Dnah8	APN	17	30,867,391 (GRCm39)	missense	possibly damaging	0.50
IGL02182:Dnah8	APN	17	31,013,737 (GRCm39)	missense	possibly damaging	0.45
IGL02233:Dnah8	APN	17	30,925,487 (GRCm39)	critical splice donor site	probably null
IGL02236:Dnah8	APN	17	30,868,747 (GRCm39)	nonsense	probably null
IGL02259:Dnah8	APN	17	30,978,588 (GRCm39)	missense	probably benign
IGL02263:Dnah8	APN	17	30,948,139 (GRCm39)	missense	probably benign	0.00
IGL02303:Dnah8	APN	17	30,932,021 (GRCm39)	missense	probably benign	0.03
IGL02341:Dnah8	APN	17	30,966,231 (GRCm39)	missense	probably damaging	1.00
IGL02351:Dnah8	APN	17	30,986,785 (GRCm39)	missense	probably damaging	1.00
IGL02358:Dnah8	APN	17	30,986,785 (GRCm39)	missense	probably damaging	1.00
IGL02377:Dnah8	APN	17	31,013,770 (GRCm39)	missense	probably damaging	0.98
IGL02390:Dnah8	APN	17	31,049,819 (GRCm39)	missense	probably benign	0.01
IGL02392:Dnah8	APN	17	31,037,025 (GRCm39)	splice site	probably benign
IGL02414:Dnah8	APN	17	30,919,387 (GRCm39)	missense	probably benign
IGL02455:Dnah8	APN	17	30,891,308 (GRCm39)	missense	probably damaging	0.99
IGL02817:Dnah8	APN	17	30,887,269 (GRCm39)	missense	probably benign
IGL02831:Dnah8	APN	17	30,931,250 (GRCm39)	missense	probably benign	0.23
IGL02863:Dnah8	APN	17	30,988,671 (GRCm39)	missense	probably damaging	1.00
IGL02894:Dnah8	APN	17	30,940,084 (GRCm39)	nonsense	probably null
IGL02954:Dnah8	APN	17	30,923,809 (GRCm39)	missense	probably benign	0.30
IGL02964:Dnah8	APN	17	30,965,735 (GRCm39)	missense	probably damaging	1.00
IGL03080:Dnah8	APN	17	30,937,980 (GRCm39)	missense	probably benign	0.01
IGL03081:Dnah8	APN	17	30,905,347 (GRCm39)	splice site	probably benign
IGL03086:Dnah8	APN	17	30,961,754 (GRCm39)	missense	probably damaging	1.00
IGL03087:Dnah8	APN	17	31,003,118 (GRCm39)	missense	probably benign
IGL03176:Dnah8	APN	17	30,913,011 (GRCm39)	missense	probably benign
IGL03191:Dnah8	APN	17	30,945,804 (GRCm39)	missense	probably damaging	0.99
IGL03210:Dnah8	APN	17	31,034,639 (GRCm39)	missense	probably damaging	0.96
IGL03252:Dnah8	APN	17	30,892,894 (GRCm39)	splice site	probably null
IGL03255:Dnah8	APN	17	30,960,355 (GRCm39)	missense	probably damaging	1.00
IGL03288:Dnah8	APN	17	30,891,323 (GRCm39)	missense	probably benign
IGL03348:Dnah8	APN	17	30,965,960 (GRCm39)	missense	probably damaging	0.99
Alternator	UTSW	17	30,984,609 (GRCm39)	missense	probably benign
armature	UTSW	17	30,927,364 (GRCm39)	missense	probably benign	0.02
Brush	UTSW	17	30,965,964 (GRCm39)	missense	probably damaging	1.00
Dynos	UTSW	17	30,934,483 (GRCm39)	missense	possibly damaging	0.84
joule	UTSW	17	30,932,072 (GRCm39)	critical splice donor site	probably null
solenoid	UTSW	17	30,960,152 (GRCm39)	missense	probably damaging	1.00
FR4340:Dnah8	UTSW	17	30,854,437 (GRCm39)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,854,451 (GRCm39)	small deletion	probably benign
FR4737:Dnah8	UTSW	17	30,854,439 (GRCm39)	small deletion	probably benign
I2288:Dnah8	UTSW	17	30,882,428 (GRCm39)	missense	probably benign
P0029:Dnah8	UTSW	17	30,984,694 (GRCm39)	missense	probably damaging	1.00
PIT4812001:Dnah8	UTSW	17	30,927,419 (GRCm39)	missense	probably benign	0.04
R0016:Dnah8	UTSW	17	30,882,290 (GRCm39)	missense	probably benign
R0035:Dnah8	UTSW	17	30,902,595 (GRCm39)	splice site	probably benign
R0062:Dnah8	UTSW	17	30,984,685 (GRCm39)	missense	probably damaging	1.00
R0062:Dnah8	UTSW	17	30,984,685 (GRCm39)	missense	probably damaging	1.00
R0087:Dnah8	UTSW	17	30,974,093 (GRCm39)	missense	probably damaging	1.00
R0090:Dnah8	UTSW	17	31,003,064 (GRCm39)	missense	probably benign	0.20
R0119:Dnah8	UTSW	17	30,934,483 (GRCm39)	missense	possibly damaging	0.84
R0164:Dnah8	UTSW	17	30,967,639 (GRCm39)	missense	probably benign
R0164:Dnah8	UTSW	17	30,967,639 (GRCm39)	missense	probably benign
R0184:Dnah8	UTSW	17	30,902,657 (GRCm39)	missense	probably benign	0.04
R0240:Dnah8	UTSW	17	30,984,653 (GRCm39)	missense	probably damaging	0.98
R0240:Dnah8	UTSW	17	30,984,653 (GRCm39)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,984,653 (GRCm39)	missense	probably damaging	0.98
R0241:Dnah8	UTSW	17	30,984,653 (GRCm39)	missense	probably damaging	0.98
R0265:Dnah8	UTSW	17	30,909,245 (GRCm39)	missense	probably benign
R0268:Dnah8	UTSW	17	30,988,681 (GRCm39)	missense	probably damaging	1.00
R0282:Dnah8	UTSW	17	30,955,130 (GRCm39)	missense	probably damaging	1.00
R0299:Dnah8	UTSW	17	30,934,483 (GRCm39)	missense	possibly damaging	0.84
R0334:Dnah8	UTSW	17	31,090,325 (GRCm39)	missense	probably damaging	0.99
R0393:Dnah8	UTSW	17	30,927,364 (GRCm39)	missense	probably benign	0.02
R0423:Dnah8	UTSW	17	30,920,955 (GRCm39)	missense	probably benign
R0470:Dnah8	UTSW	17	30,927,514 (GRCm39)	splice site	probably benign
R0477:Dnah8	UTSW	17	30,974,054 (GRCm39)	missense	probably damaging	1.00
R0490:Dnah8	UTSW	17	30,919,393 (GRCm39)	missense	probably benign
R0499:Dnah8	UTSW	17	30,934,483 (GRCm39)	missense	possibly damaging	0.84
R0582:Dnah8	UTSW	17	30,937,935 (GRCm39)	missense	probably benign	0.01
R0601:Dnah8	UTSW	17	30,927,332 (GRCm39)	missense	probably benign	0.06
R0646:Dnah8	UTSW	17	30,903,147 (GRCm39)	missense	probably damaging	0.97
R0665:Dnah8	UTSW	17	30,955,129 (GRCm39)	missense	probably damaging	0.99
R0800:Dnah8	UTSW	17	30,923,636 (GRCm39)	missense	probably benign
R0843:Dnah8	UTSW	17	31,032,069 (GRCm39)	missense	probably damaging	1.00
R0940:Dnah8	UTSW	17	31,022,217 (GRCm39)	missense	probably damaging	1.00
R0964:Dnah8	UTSW	17	30,892,894 (GRCm39)	splice site	probably null
R1102:Dnah8	UTSW	17	31,073,738 (GRCm39)	splice site	probably null
R1137:Dnah8	UTSW	17	31,074,910 (GRCm39)	missense	probably damaging	1.00
R1342:Dnah8	UTSW	17	30,939,974 (GRCm39)	missense	probably damaging	0.99
R1375:Dnah8	UTSW	17	30,956,269 (GRCm39)	missense	probably damaging	1.00
R1377:Dnah8	UTSW	17	31,059,596 (GRCm39)	nonsense	probably null
R1464:Dnah8	UTSW	17	30,914,147 (GRCm39)	missense	possibly damaging	0.81
R1464:Dnah8	UTSW	17	30,914,147 (GRCm39)	missense	possibly damaging	0.81
R1470:Dnah8	UTSW	17	30,966,251 (GRCm39)	nonsense	probably null
R1470:Dnah8	UTSW	17	30,966,251 (GRCm39)	nonsense	probably null
R1497:Dnah8	UTSW	17	30,971,049 (GRCm39)	missense	probably damaging	1.00
R1513:Dnah8	UTSW	17	30,892,862 (GRCm39)	missense	probably benign
R1541:Dnah8	UTSW	17	30,966,221 (GRCm39)	missense	probably damaging	1.00
R1563:Dnah8	UTSW	17	30,854,638 (GRCm39)	missense	probably benign	0.07
R1634:Dnah8	UTSW	17	30,932,072 (GRCm39)	critical splice donor site	probably null
R1670:Dnah8	UTSW	17	30,944,098 (GRCm39)	missense	probably damaging	1.00
R1710:Dnah8	UTSW	17	31,073,914 (GRCm39)	missense	probably damaging	1.00
R1743:Dnah8	UTSW	17	30,988,625 (GRCm39)	missense	probably benign	0.28
R1761:Dnah8	UTSW	17	30,998,890 (GRCm39)	missense	probably damaging	1.00
R1785:Dnah8	UTSW	17	30,941,911 (GRCm39)	missense	probably damaging	0.98
R1804:Dnah8	UTSW	17	30,927,381 (GRCm39)	missense	probably benign	0.00
R1808:Dnah8	UTSW	17	30,903,160 (GRCm39)	missense	probably damaging	1.00
R1824:Dnah8	UTSW	17	30,950,154 (GRCm39)	missense	possibly damaging	0.67
R1836:Dnah8	UTSW	17	31,093,901 (GRCm39)	missense	possibly damaging	0.94
R1935:Dnah8	UTSW	17	30,854,479 (GRCm39)	missense	unknown
R1935:Dnah8	UTSW	17	30,945,870 (GRCm39)	splice site	probably benign
R1940:Dnah8	UTSW	17	30,950,181 (GRCm39)	missense	probably damaging	1.00
R1946:Dnah8	UTSW	17	30,931,359 (GRCm39)	missense	probably benign	0.00
R2025:Dnah8	UTSW	17	30,950,133 (GRCm39)	missense	probably damaging	0.99
R2038:Dnah8	UTSW	17	30,977,255 (GRCm39)	missense	probably damaging	1.00
R2042:Dnah8	UTSW	17	30,854,632 (GRCm39)	missense	probably benign	0.01
R2148:Dnah8	UTSW	17	30,956,232 (GRCm39)	missense	probably damaging	1.00
R2177:Dnah8	UTSW	17	30,872,367 (GRCm39)	missense	probably benign
R2180:Dnah8	UTSW	17	31,059,621 (GRCm39)	missense	probably benign	0.00
R2262:Dnah8	UTSW	17	30,892,809 (GRCm39)	missense	probably damaging	1.00
R2263:Dnah8	UTSW	17	30,892,809 (GRCm39)	missense	probably damaging	1.00
R2328:Dnah8	UTSW	17	31,013,718 (GRCm39)	missense	probably damaging	1.00
R2357:Dnah8	UTSW	17	31,093,909 (GRCm39)	missense	probably benign	0.00
R2357:Dnah8	UTSW	17	30,990,846 (GRCm39)	missense	probably benign
R2360:Dnah8	UTSW	17	30,896,178 (GRCm39)	missense	probably benign	0.22
R2496:Dnah8	UTSW	17	31,070,705 (GRCm39)	missense	probably damaging	1.00
R2497:Dnah8	UTSW	17	30,960,339 (GRCm39)	nonsense	probably null
R2509:Dnah8	UTSW	17	30,994,019 (GRCm39)	missense	probably benign	0.02
R3114:Dnah8	UTSW	17	31,052,542 (GRCm39)	missense	probably benign	0.04
R3708:Dnah8	UTSW	17	30,958,631 (GRCm39)	missense	probably damaging	0.98
R3720:Dnah8	UTSW	17	31,073,872 (GRCm39)	missense	probably damaging	1.00
R3722:Dnah8	UTSW	17	31,073,872 (GRCm39)	missense	probably damaging	1.00
R3727:Dnah8	UTSW	17	30,958,622 (GRCm39)	nonsense	probably null
R3747:Dnah8	UTSW	17	31,003,148 (GRCm39)	nonsense	probably null
R3748:Dnah8	UTSW	17	31,003,148 (GRCm39)	nonsense	probably null
R3749:Dnah8	UTSW	17	31,003,148 (GRCm39)	nonsense	probably null
R3787:Dnah8	UTSW	17	30,974,015 (GRCm39)	missense	probably damaging	1.00
R3790:Dnah8	UTSW	17	31,073,872 (GRCm39)	missense	probably damaging	1.00
R3804:Dnah8	UTSW	17	30,889,621 (GRCm39)	missense	probably benign	0.00
R3857:Dnah8	UTSW	17	30,882,396 (GRCm39)	missense	probably damaging	0.96
R3898:Dnah8	UTSW	17	31,073,872 (GRCm39)	missense	probably damaging	1.00
R3899:Dnah8	UTSW	17	31,073,872 (GRCm39)	missense	probably damaging	1.00
R3938:Dnah8	UTSW	17	31,073,911 (GRCm39)	missense	probably damaging	1.00
R3943:Dnah8	UTSW	17	30,913,039 (GRCm39)	splice site	probably benign
R4091:Dnah8	UTSW	17	30,988,813 (GRCm39)	missense	probably damaging	1.00
R4291:Dnah8	UTSW	17	30,967,533 (GRCm39)	missense	probably benign
R4326:Dnah8	UTSW	17	30,971,066 (GRCm39)	missense	probably benign	0.04
R4346:Dnah8	UTSW	17	30,944,072 (GRCm39)	missense	possibly damaging	0.92
R4429:Dnah8	UTSW	17	30,971,120 (GRCm39)	missense	probably damaging	1.00
R4457:Dnah8	UTSW	17	31,032,125 (GRCm39)	missense	probably benign
R4475:Dnah8	UTSW	17	30,875,959 (GRCm39)	missense	probably benign	0.12
R4565:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4566:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4568:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4573:Dnah8	UTSW	17	30,919,380 (GRCm39)	missense	probably benign	0.00
R4580:Dnah8	UTSW	17	30,881,026 (GRCm39)	missense	probably benign	0.00
R4585:Dnah8	UTSW	17	30,970,541 (GRCm39)	missense	probably benign	0.01
R4611:Dnah8	UTSW	17	30,903,211 (GRCm39)	missense	probably damaging	1.00
R4720:Dnah8	UTSW	17	30,902,608 (GRCm39)	missense	probably benign	0.08
R4721:Dnah8	UTSW	17	30,944,140 (GRCm39)	missense	probably damaging	1.00
R4727:Dnah8	UTSW	17	31,070,721 (GRCm39)	missense	probably damaging	1.00
R4731:Dnah8	UTSW	17	30,994,035 (GRCm39)	missense	probably null	0.02
R4732:Dnah8	UTSW	17	30,994,035 (GRCm39)	missense	probably null	0.02
R4733:Dnah8	UTSW	17	30,994,035 (GRCm39)	missense	probably null	0.02
R4798:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4814:Dnah8	UTSW	17	30,986,898 (GRCm39)	missense	probably damaging	1.00
R4892:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4894:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4900:Dnah8	UTSW	17	30,965,949 (GRCm39)	missense	probably damaging	1.00
R4901:Dnah8	UTSW	17	31,059,688 (GRCm39)	critical splice donor site	probably null
R4913:Dnah8	UTSW	17	31,038,113 (GRCm39)	missense	probably damaging	0.99
R4931:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4932:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4933:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R4942:Dnah8	UTSW	17	30,948,116 (GRCm39)	missense	probably benign
R4969:Dnah8	UTSW	17	30,941,988 (GRCm39)	missense	probably damaging	1.00
R4975:Dnah8	UTSW	17	30,875,959 (GRCm39)	missense	probably benign	0.12
R4977:Dnah8	UTSW	17	30,882,275 (GRCm39)	missense	probably benign	0.00
R5001:Dnah8	UTSW	17	31,006,159 (GRCm39)	missense	probably damaging	1.00
R5011:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5013:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5014:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5024:Dnah8	UTSW	17	30,955,070 (GRCm39)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5075:Dnah8	UTSW	17	31,019,505 (GRCm39)	missense	probably damaging	1.00
R5075:Dnah8	UTSW	17	30,958,731 (GRCm39)	critical splice donor site	probably null
R5112:Dnah8	UTSW	17	30,950,012 (GRCm39)	missense	probably benign	0.02
R5121:Dnah8	UTSW	17	31,029,327 (GRCm39)	missense	probably benign	0.14
R5138:Dnah8	UTSW	17	30,984,571 (GRCm39)	missense	probably damaging	0.99
R5151:Dnah8	UTSW	17	30,931,269 (GRCm39)	missense	probably benign	0.06
R5191:Dnah8	UTSW	17	30,965,739 (GRCm39)	missense	probably damaging	1.00
R5238:Dnah8	UTSW	17	31,009,891 (GRCm39)	missense	probably damaging	1.00
R5260:Dnah8	UTSW	17	30,919,393 (GRCm39)	missense	probably benign
R5358:Dnah8	UTSW	17	30,965,928 (GRCm39)	missense	probably damaging	1.00
R5403:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5404:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5482:Dnah8	UTSW	17	31,019,521 (GRCm39)	missense	probably damaging	0.96
R5489:Dnah8	UTSW	17	31,009,930 (GRCm39)	missense	probably damaging	1.00
R5513:Dnah8	UTSW	17	30,971,890 (GRCm39)	missense	probably damaging	0.99
R5635:Dnah8	UTSW	17	30,925,360 (GRCm39)	missense	probably benign	0.00
R5640:Dnah8	UTSW	17	31,022,082 (GRCm39)	missense	probably damaging	1.00
R5649:Dnah8	UTSW	17	31,019,561 (GRCm39)	missense	probably benign	0.13
R5662:Dnah8	UTSW	17	30,956,307 (GRCm39)	missense	probably damaging	1.00
R5673:Dnah8	UTSW	17	31,022,235 (GRCm39)	missense	probably damaging	1.00
R5677:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5699:Dnah8	UTSW	17	31,029,298 (GRCm39)	missense	probably benign	0.22
R5737:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5738:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R5739:Dnah8	UTSW	17	30,937,981 (GRCm39)	missense	probably benign	0.00
R5766:Dnah8	UTSW	17	30,909,235 (GRCm39)	missense	probably benign	0.01
R5790:Dnah8	UTSW	17	31,093,978 (GRCm39)	missense	probably damaging	0.98
R5848:Dnah8	UTSW	17	30,947,165 (GRCm39)	missense	possibly damaging	0.69
R5854:Dnah8	UTSW	17	31,013,737 (GRCm39)	missense	possibly damaging	0.45
R5885:Dnah8	UTSW	17	31,013,691 (GRCm39)	missense	probably damaging	1.00
R5886:Dnah8	UTSW	17	31,013,691 (GRCm39)	missense	probably damaging	1.00
R5887:Dnah8	UTSW	17	31,013,691 (GRCm39)	missense	probably damaging	1.00
R5899:Dnah8	UTSW	17	30,875,659 (GRCm39)	missense	probably benign	0.32
R5979:Dnah8	UTSW	17	31,034,638 (GRCm39)	nonsense	probably null
R5986:Dnah8	UTSW	17	31,070,604 (GRCm39)	missense	possibly damaging	0.83
R5999:Dnah8	UTSW	17	30,882,279 (GRCm39)	missense	probably benign	0.32
R6042:Dnah8	UTSW	17	30,966,239 (GRCm39)	missense	probably damaging	1.00
R6175:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6181:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6237:Dnah8	UTSW	17	30,966,828 (GRCm39)	nonsense	probably null
R6239:Dnah8	UTSW	17	31,029,333 (GRCm39)	missense	probably damaging	0.99
R6337:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6365:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6416:Dnah8	UTSW	17	30,984,609 (GRCm39)	missense	probably benign
R6443:Dnah8	UTSW	17	30,990,859 (GRCm39)	missense	probably benign	0.10
R6478:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6479:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6480:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6481:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6533:Dnah8	UTSW	17	30,965,964 (GRCm39)	missense	probably damaging	1.00
R6606:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6608:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6610:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6675:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6723:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6724:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6754:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6755:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6759:Dnah8	UTSW	17	30,882,266 (GRCm39)	splice site	probably null
R6765:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6766:Dnah8	UTSW	17	30,967,542 (GRCm39)	missense	probably benign	0.00
R6778:Dnah8	UTSW	17	30,854,640 (GRCm39)	missense	probably benign	0.00
R6781:Dnah8	UTSW	17	30,984,698 (GRCm39)	frame shift	probably null
R6788:Dnah8	UTSW	17	30,867,439 (GRCm39)	missense	probably benign	0.14
R6814:Dnah8	UTSW	17	30,981,653 (GRCm39)	missense	probably damaging	1.00
R6825:Dnah8	UTSW	17	30,960,147 (GRCm39)	missense	probably damaging	1.00
R6838:Dnah8	UTSW	17	30,929,525 (GRCm39)	missense	probably damaging	1.00
R6872:Dnah8	UTSW	17	30,981,653 (GRCm39)	missense	probably damaging	1.00
R6877:Dnah8	UTSW	17	30,965,933 (GRCm39)	missense	probably damaging	1.00
R6944:Dnah8	UTSW	17	31,013,633 (GRCm39)	missense	probably benign	0.09
R6982:Dnah8	UTSW	17	30,986,899 (GRCm39)	missense	probably benign	0.03
R6984:Dnah8	UTSW	17	30,958,712 (GRCm39)	missense	probably damaging	1.00
R6987:Dnah8	UTSW	17	30,881,065 (GRCm39)	missense	possibly damaging	0.95
R6988:Dnah8	UTSW	17	30,862,249 (GRCm39)	missense	probably damaging	1.00
R7099:Dnah8	UTSW	17	30,923,698 (GRCm39)	missense	possibly damaging	0.93
R7106:Dnah8	UTSW	17	30,960,152 (GRCm39)	missense	probably damaging	1.00
R7112:Dnah8	UTSW	17	31,090,366 (GRCm39)	missense	possibly damaging	0.79
R7146:Dnah8	UTSW	17	30,988,618 (GRCm39)	missense	possibly damaging	0.90
R7146:Dnah8	UTSW	17	30,863,591 (GRCm39)	missense	probably benign	0.01
R7309:Dnah8	UTSW	17	31,093,988 (GRCm39)	missense	probably damaging	1.00
R7324:Dnah8	UTSW	17	31,003,099 (GRCm39)	missense	probably benign	0.01
R7373:Dnah8	UTSW	17	30,986,939 (GRCm39)	critical splice donor site	probably null
R7423:Dnah8	UTSW	17	30,923,743 (GRCm39)	missense	possibly damaging	0.86
R7430:Dnah8	UTSW	17	30,925,363 (GRCm39)	missense	probably damaging	0.98
R7450:Dnah8	UTSW	17	31,006,165 (GRCm39)	missense	probably damaging	0.99
R7580:Dnah8	UTSW	17	30,994,077 (GRCm39)	missense	probably damaging	0.98
R7604:Dnah8	UTSW	17	31,032,069 (GRCm39)	missense	probably damaging	1.00
R7635:Dnah8	UTSW	17	31,004,081 (GRCm39)	missense	probably damaging	1.00
R7646:Dnah8	UTSW	17	30,868,651 (GRCm39)	missense	probably benign	0.00
R7685:Dnah8	UTSW	17	30,876,947 (GRCm39)	missense	probably damaging	1.00
R7793:Dnah8	UTSW	17	31,074,918 (GRCm39)	missense	probably benign	0.20
R7827:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R7866:Dnah8	UTSW	17	31,093,901 (GRCm39)	missense	possibly damaging	0.94
R7877:Dnah8	UTSW	17	30,882,348 (GRCm39)	missense	probably benign
R7891:Dnah8	UTSW	17	30,931,263 (GRCm39)	missense	probably benign	0.09
R7977:Dnah8	UTSW	17	30,963,498 (GRCm39)	missense	probably damaging	1.00
R7987:Dnah8	UTSW	17	30,963,498 (GRCm39)	missense	probably damaging	1.00
R8025:Dnah8	UTSW	17	30,960,311 (GRCm39)	nonsense	probably null
R8076:Dnah8	UTSW	17	31,003,127 (GRCm39)	missense	possibly damaging	0.94
R8170:Dnah8	UTSW	17	30,892,797 (GRCm39)	missense	probably damaging	1.00
R8199:Dnah8	UTSW	17	31,090,393 (GRCm39)	missense	probably benign	0.06
R8253:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R8270:Dnah8	UTSW	17	31,059,687 (GRCm39)	missense	probably damaging	1.00
R8291:Dnah8	UTSW	17	30,984,701 (GRCm39)	missense	probably damaging	1.00
R8334:Dnah8	UTSW	17	30,988,805 (GRCm39)	missense	probably benign	0.12
R8348:Dnah8	UTSW	17	30,892,814 (GRCm39)	missense	probably benign
R8348:Dnah8	UTSW	17	30,955,121 (GRCm39)	missense	probably damaging	0.96
R8354:Dnah8	UTSW	17	30,862,234 (GRCm39)	missense	probably benign	0.17
R8355:Dnah8	UTSW	17	30,914,152 (GRCm39)	missense	possibly damaging	0.89
R8439:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R8448:Dnah8	UTSW	17	30,892,814 (GRCm39)	missense	probably benign
R8459:Dnah8	UTSW	17	30,944,221 (GRCm39)	critical splice donor site	probably null
R8462:Dnah8	UTSW	17	30,875,603 (GRCm39)	missense	probably damaging	1.00
R8506:Dnah8	UTSW	17	30,940,108 (GRCm39)	missense	probably benign
R8524:Dnah8	UTSW	17	30,934,472 (GRCm39)	missense	possibly damaging	0.95
R8555:Dnah8	UTSW	17	30,940,084 (GRCm39)	nonsense	probably null
R8698:Dnah8	UTSW	17	31,094,009 (GRCm39)	missense	probably damaging	1.00
R8719:Dnah8	UTSW	17	30,960,289 (GRCm39)	missense	probably damaging	0.97
R8778:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R8781:Dnah8	UTSW	17	30,944,078 (GRCm39)	missense	probably damaging	1.00
R8821:Dnah8	UTSW	17	31,013,712 (GRCm39)	missense	probably damaging	1.00
R8864:Dnah8	UTSW	17	30,981,616 (GRCm39)	missense	possibly damaging	0.95
R8885:Dnah8	UTSW	17	30,927,286 (GRCm39)	missense	possibly damaging	0.83
R8983:Dnah8	UTSW	17	31,070,628 (GRCm39)	missense	probably damaging	0.98
R8994:Dnah8	UTSW	17	31,009,807 (GRCm39)	missense	probably benign	0.05
R9031:Dnah8	UTSW	17	30,956,401 (GRCm39)	missense	probably damaging	1.00
R9068:Dnah8	UTSW	17	30,975,729 (GRCm39)	missense	possibly damaging	0.63
R9225:Dnah8	UTSW	17	30,854,647 (GRCm39)	missense	probably benign	0.01
R9280:Dnah8	UTSW	17	31,004,071 (GRCm39)	missense	possibly damaging	0.52
R9291:Dnah8	UTSW	17	30,944,099 (GRCm39)	missense	probably damaging	1.00
R9314:Dnah8	UTSW	17	30,990,857 (GRCm39)	missense	probably benign
R9347:Dnah8	UTSW	17	30,927,333 (GRCm39)	missense	probably benign	0.00
R9393:Dnah8	UTSW	17	30,872,361 (GRCm39)	missense	possibly damaging	0.53
R9415:Dnah8	UTSW	17	31,029,297 (GRCm39)	missense	probably benign	0.02
R9458:Dnah8	UTSW	17	31,049,777 (GRCm39)	missense	probably damaging	1.00
R9465:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R9518:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R9524:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R9564:Dnah8	UTSW	17	30,932,021 (GRCm39)	missense	probably benign	0.07
R9587:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R9599:Dnah8	UTSW	17	30,979,841 (GRCm39)	frame shift	probably null
R9641:Dnah8	UTSW	17	30,932,029 (GRCm39)	missense	probably benign	0.13
R9674:Dnah8	UTSW	17	30,998,112 (GRCm39)	missense	possibly damaging	0.84
R9679:Dnah8	UTSW	17	31,037,115 (GRCm39)	missense	probably benign
R9789:Dnah8	UTSW	17	30,980,104 (GRCm39)	critical splice donor site	probably null
RF027:Dnah8	UTSW	17	30,854,450 (GRCm39)	frame shift	probably null
X0001:Dnah8	UTSW	17	30,967,654 (GRCm39)	missense	probably damaging	1.00
X0013:Dnah8	UTSW	17	31,038,160 (GRCm39)	missense	possibly damaging	0.71
Z1176:Dnah8	UTSW	17	30,867,514 (GRCm39)	missense	probably benign
Z1177:Dnah8	UTSW	17	30,932,069 (GRCm39)	missense	probably null	1.00
Z1177:Dnah8	UTSW	17	30,913,007 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GGGGATACACCTGTGATTGACAGC -3'
(R):5'- AAGCTCTCCAGCATTAGCGAGGAC -3'

Sequencing Primer
(F):5'- CTGATGGAAGGGTATAGCCAGC -3'
(R):5'- gggagggaggaggggag -3'

Posted On

2013-04-11