Mutagenetix > Incidental Mutation

Incidental Mutation 'R1768:Trank1'

194601

Institutional Source

Beutler Lab

Gene Symbol

Trank1

Ensembl Gene

ENSMUSG00000062296

Gene Name

tetratricopeptide repeat and ankyrin repeat containing 1

Synonyms

A230061D21Rik, LOC235639, C030048J01Rik, Lba1

MMRRC Submission

039799-MU

Accession Numbers

Genbank: NM_001164659.1; Ensembl: ENSMUST00000078626

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1768 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

111311739-111395775 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

G to A at 111392927 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Valine to Methionine at position 2911 (V2911M)

Ref Sequence

ENSEMBL: ENSMUSP00000077697 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000078626]

AlphaFold

no structure available at present

Predicted Effect

probably damaging
Transcript: ENSMUST00000078626
AA Change: V2911M

PolyPhen 2 Score 0.959 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000077697
Gene: ENSMUSG00000062296
AA Change: V2911M

Domain	Start	End	E-Value	Type
low complexity region	4	30	N/A	INTRINSIC
low complexity region	34	52	N/A	INTRINSIC
low complexity region	113	129	N/A	INTRINSIC
Blast:TPR	144	177	1e-15	BLAST
Blast:TPR	178	209	8e-13	BLAST
Blast:ANK	332	361	1e-6	BLAST
ANK	369	405	5.29e0	SMART
ANK	538	567	2.11e2	SMART
ANK	572	609	7.29e2	SMART
ANK	621	652	1.21e2	SMART
low complexity region	887	895	N/A	INTRINSIC
low complexity region	1152	1172	N/A	INTRINSIC
Blast:AAA	1351	1569	1e-6	BLAST
low complexity region	2166	2177	N/A	INTRINSIC
low complexity region	2395	2411	N/A	INTRINSIC
low complexity region	2636	2649	N/A	INTRINSIC
low complexity region	2966	2983	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000196945

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000197650

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000198890

Meta Mutation Damage Score

0.6467

Coding Region Coverage

1x: 97.4%
3x: 96.9%
10x: 95.3%
20x: 92.4%

Validation Efficiency

91% (107/117)

Allele List at MGI

All alleles(2) : Targeted, other(2)

Other mutations in this stock

Total: 112 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4921524L21Rik	G	C	18: 6,623,470 (GRCm38)	R60P	possibly damaging	Het
Aox2	T	A	1: 58,354,195 (GRCm38)	C1199S	probably benign	Het
Arhgap18	G	A	10: 26,887,861 (GRCm38)	M482I	probably damaging	Het
Arhgap18	G	T	10: 26,887,862 (GRCm38)	A483S	probably damaging	Het
Arid4a	G	A	12: 71,075,338 (GRCm38)	S509N	probably benign	Het
BC051019	T	C	7: 109,723,174 (GRCm38)	T38A	probably benign	Het
Bcam	T	C	7: 19,765,618 (GRCm38)	N192S	probably null	Het
Bend5	A	T	4: 111,454,241 (GRCm38)	K351*	probably null	Het
Bicdl2	T	A	17: 23,665,949 (GRCm38)	M208K	probably damaging	Het
Ccdc155	T	A	7: 45,188,803 (GRCm38)		probably null	Het
Ccp110	A	T	7: 118,726,024 (GRCm38)		probably null	Het
Cdc6	A	T	11: 98,912,217 (GRCm38)	T328S	probably damaging	Het
Cdk5rap2	G	T	4: 70,307,233 (GRCm38)	N558K	probably benign	Het
Cdkn1c	C	T	7: 143,459,121 (GRCm38)	R146K	probably benign	Het
Ceacam18	G	A	7: 43,648,494 (GRCm38)	C371Y	probably benign	Het
Cep95	T	A	11: 106,806,351 (GRCm38)	C233*	probably null	Het
Chrnd	A	G	1: 87,194,928 (GRCm38)	I144V	probably benign	Het
Col6a4	T	A	9: 106,080,100 (GRCm38)	Q175L	probably benign	Het
Cym	A	T	3: 107,213,500 (GRCm38)	V263E	probably damaging	Het
Cyp2a4	G	T	7: 26,312,772 (GRCm38)	V327F	possibly damaging	Het
Dhx29	T	A	13: 112,948,240 (GRCm38)	M664K	probably damaging	Het
Dlec1	T	G	9: 119,146,007 (GRCm38)		probably null	Het
Dna2	T	C	10: 62,957,084 (GRCm38)	Y293H	probably benign	Het
Dnase1l3	T	A	14: 7,974,104 (GRCm38)	N196Y	probably damaging	Het
Eea1	T	A	10: 95,996,960 (GRCm38)	D222E	probably damaging	Het
Efcab14	A	T	4: 115,752,919 (GRCm38)		probably null	Het
Entpd5	C	T	12: 84,386,211 (GRCm38)	R189H	probably benign	Het
Exoc4	A	T	6: 33,758,050 (GRCm38)	K534M	probably damaging	Het
Extl1	T	A	4: 134,371,138 (GRCm38)	Y194F	probably benign	Het
Eya1	A	G	1: 14,253,075 (GRCm38)	L161S	possibly damaging	Het
Fam163b	T	C	2: 27,112,862 (GRCm38)	E41G	possibly damaging	Het
Fam180a	A	C	6: 35,315,352 (GRCm38)	S40A	probably benign	Het
Fbxl4	T	C	4: 22,385,950 (GRCm38)	S186P	probably benign	Het
Fbxw19	A	T	9: 109,494,772 (GRCm38)	L45*	probably null	Het
Fgf14	G	T	14: 124,676,512 (GRCm38)	T69N	probably benign	Het
Flt1	A	G	5: 147,672,709 (GRCm38)	Y432H	probably damaging	Het
Frmd4b	A	T	6: 97,306,764 (GRCm38)	L374Q	possibly damaging	Het
G6pc2	T	A	2: 69,222,977 (GRCm38)	V125D	probably damaging	Het
Gna15	A	T	10: 81,512,120 (GRCm38)	L164Q	probably damaging	Het
Gnaz	C	A	10: 74,991,870 (GRCm38)	D151E	possibly damaging	Het
Has1	T	C	17: 17,850,300 (GRCm38)	T120A	probably benign	Het
Hectd4	T	A	5: 121,358,303 (GRCm38)	D3919E	possibly damaging	Het
Hs3st5	A	G	10: 36,833,169 (GRCm38)	I233M	probably benign	Het
Ilf3	T	C	9: 21,403,142 (GRCm38)		probably benign	Het
Inpp5b	T	A	4: 124,793,276 (GRCm38)	L765*	probably null	Het
Insr	A	T	8: 3,159,561 (GRCm38)	I1174N	probably damaging	Het
Kcnq3	A	G	15: 66,005,906 (GRCm38)	L445P	probably damaging	Het
Kctd20	A	T	17: 28,962,850 (GRCm38)	N159Y	probably damaging	Het
Kctd20	A	T	17: 28,966,781 (GRCm38)	D366V	probably damaging	Het
Klk15	T	C	7: 43,938,333 (GRCm38)		probably benign	Het
Lama4	T	G	10: 39,103,501 (GRCm38)	N1658K	possibly damaging	Het
Lonrf2	G	A	1: 38,813,276 (GRCm38)	P165S	probably benign	Het
Mas1	T	C	17: 12,841,699 (GRCm38)	Y279C	probably damaging	Het
Mast2	G	T	4: 116,306,959 (GRCm38)	D1747E	probably damaging	Het
Mest	G	A	6: 30,745,139 (GRCm38)	M235I	probably benign	Het
Mfsd6	A	G	1: 52,660,805 (GRCm38)		probably null	Het
Mllt10	T	A	2: 18,162,846 (GRCm38)	S449R	probably damaging	Het
Mon2	T	A	10: 123,013,763 (GRCm38)	T1211S	probably benign	Het
Mrnip	G	A	11: 50,176,861 (GRCm38)	C27Y	probably damaging	Het
Myh15	A	T	16: 49,163,135 (GRCm38)	T1538S	probably benign	Het
Nfatc2ip	A	G	7: 126,390,462 (GRCm38)	V250A	probably benign	Het
Npy1r	A	G	8: 66,704,525 (GRCm38)	D199G	possibly damaging	Het
Numbl	A	G	7: 27,280,954 (GRCm38)	T454A	probably benign	Het
Nutm2	T	G	13: 50,473,116 (GRCm38)	F436V	probably damaging	Het
Olfr1112	T	A	2: 87,191,698 (GRCm38)	S4T	probably benign	Het
Olfr330	A	G	11: 58,529,776 (GRCm38)	L70P	probably damaging	Het
Olfr458	A	G	6: 42,460,677 (GRCm38)	L114S	probably damaging	Het
Olfr556	A	G	7: 102,670,301 (GRCm38)	Y127C	probably damaging	Het
Olfr631	C	T	7: 103,929,725 (GRCm38)	R301*	probably null	Het
Olfr64	A	G	7: 103,893,277 (GRCm38)	S153P	probably benign	Het
Olfr676	A	G	7: 105,035,950 (GRCm38)	S251G	probably benign	Het
Olfr707	G	T	7: 106,891,978 (GRCm38)	L44M	probably damaging	Het
Olfr707	A	T	7: 106,891,977 (GRCm38)		probably null	Het
Olfr876	T	A	9: 37,804,303 (GRCm38)	Y131N	probably damaging	Het
Opa1	T	C	16: 29,620,810 (GRCm38)	S773P	probably benign	Het
Pde8a	G	C	7: 81,300,723 (GRCm38)		probably null	Het
Pgam1	T	C	19: 41,917,705 (GRCm38)	F232S	probably damaging	Het
Pgk1	T	A	X: 106,200,308 (GRCm38)	V303E	possibly damaging	Het
Pirb	A	T	7: 3,717,190 (GRCm38)	C395S	probably damaging	Het
Plxnc1	C	T	10: 94,844,322 (GRCm38)	V824I	probably benign	Het
Ppp6r1	A	G	7: 4,633,692 (GRCm38)		probably null	Het
Rapgef4	C	A	2: 72,225,787 (GRCm38)		probably benign	Het
Rars	T	A	11: 35,809,638 (GRCm38)	T539S	probably damaging	Het
Rbm44	G	T	1: 91,153,957 (GRCm38)		probably null	Het
RP23-114B10.6	T	C	8: 69,373,558 (GRCm38)	I119M	unknown	Het
Samd4b	A	G	7: 28,413,892 (GRCm38)	I216T	probably benign	Het
Serpine2	A	C	1: 79,816,815 (GRCm38)	F134V	probably damaging	Het
Shmt1	A	G	11: 60,792,964 (GRCm38)	Y341H	probably damaging	Het
Slc23a2	C	A	2: 132,075,641 (GRCm38)	V226F	probably benign	Het
Slc23a4	A	G	6: 34,956,961 (GRCm38)	I69T	probably damaging	Het
Slc37a1	C	A	17: 31,333,678 (GRCm38)	T319K	possibly damaging	Het
Slc6a4	A	T	11: 77,013,252 (GRCm38)	T178S	probably damaging	Het
Smarca4	G	A	9: 21,701,183 (GRCm38)	A1588T	possibly damaging	Het
Spag17	A	T	3: 100,027,352 (GRCm38)	Y650F	possibly damaging	Het
Stab2	C	T	10: 87,003,008 (GRCm38)	G65S	probably damaging	Het
Stambpl1	C	G	19: 34,226,721 (GRCm38)	N70K	probably damaging	Het
Stip1	C	A	19: 7,021,797 (GRCm38)	C471F	probably damaging	Het
Taf1	T	C	X: 101,540,894 (GRCm38)	S223P	probably benign	Het
Tchh	C	A	3: 93,443,575 (GRCm38)	N107K	possibly damaging	Het
Tenm3	A	C	8: 48,232,104 (GRCm38)	H2432Q	probably damaging	Het
Tmem243	A	G	5: 9,118,548 (GRCm38)	N110S	probably damaging	Het
Toe1	A	T	4: 116,804,879 (GRCm38)	I306F	probably benign	Het
Trpm4	A	G	7: 45,308,612 (GRCm38)	I811T	probably damaging	Het
Tspear	T	A	10: 77,875,116 (GRCm38)		probably null	Het
Ttc28	A	T	5: 111,277,168 (GRCm38)	I1589F	possibly damaging	Het
Tubgcp3	A	G	8: 12,649,686 (GRCm38)		probably benign	Het
U2af2	C	A	7: 5,067,545 (GRCm38)	R78S	probably benign	Het
Wdr17	A	T	8: 54,673,654 (GRCm38)	D388E	possibly damaging	Het
Wdr3	A	T	3: 100,153,870 (GRCm38)	S261T	probably benign	Het
Zfp667	A	G	7: 6,305,067 (GRCm38)	N245D	possibly damaging	Het
Zfp692	A	G	11: 58,310,176 (GRCm38)		probably benign	Het
Zfp729a	T	C	13: 67,619,251 (GRCm38)	H953R	probably benign	Het

Other mutations in Trank1

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00234:Trank1	APN	9	111,392,609 (GRCm38)	missense	probably damaging	1.00
IGL00467:Trank1	APN	9	111,364,666 (GRCm38)	splice site	probably benign
IGL00569:Trank1	APN	9	111,345,511 (GRCm38)	missense	possibly damaging	0.69
IGL00585:Trank1	APN	9	111,349,290 (GRCm38)	missense	possibly damaging	0.82
IGL01070:Trank1	APN	9	111,366,793 (GRCm38)	missense	probably damaging	1.00
IGL01134:Trank1	APN	9	111,391,781 (GRCm38)	missense	probably benign
IGL01154:Trank1	APN	9	111,386,400 (GRCm38)	missense	probably benign	0.00
IGL01355:Trank1	APN	9	111,365,520 (GRCm38)	missense	possibly damaging	0.94
IGL01407:Trank1	APN	9	111,364,722 (GRCm38)	missense	probably damaging	0.99
IGL01410:Trank1	APN	9	111,365,049 (GRCm38)	missense	probably benign	0.00
IGL01410:Trank1	APN	9	111,365,259 (GRCm38)	missense	probably benign	0.00
IGL01504:Trank1	APN	9	111,373,544 (GRCm38)	missense	probably damaging	1.00
IGL01744:Trank1	APN	9	111,349,363 (GRCm38)	missense	probably damaging	1.00
IGL02043:Trank1	APN	9	111,363,960 (GRCm38)	missense	probably damaging	0.98
IGL02104:Trank1	APN	9	111,390,712 (GRCm38)	missense	possibly damaging	0.85
IGL02193:Trank1	APN	9	111,367,276 (GRCm38)	missense	probably benign	0.43
IGL02581:Trank1	APN	9	111,383,125 (GRCm38)	missense	probably benign	0.00
IGL02630:Trank1	APN	9	111,373,075 (GRCm38)	missense	possibly damaging	0.70
IGL02839:Trank1	APN	9	111,364,756 (GRCm38)	missense	probably damaging	1.00
IGL02897:Trank1	APN	9	111,367,517 (GRCm38)	missense	probably damaging	0.99
IGL03065:Trank1	APN	9	111,390,293 (GRCm38)	missense	possibly damaging	0.64
IGL03123:Trank1	APN	9	111,367,407 (GRCm38)	missense	probably damaging	1.00
IGL03143:Trank1	APN	9	111,366,087 (GRCm38)	missense	probably damaging	1.00
IGL03323:Trank1	APN	9	111,352,116 (GRCm38)	missense	probably damaging	1.00
1mM(1):Trank1	UTSW	9	111,392,981 (GRCm38)	missense	probably damaging	1.00
PIT4486001:Trank1	UTSW	9	111,390,107 (GRCm38)	missense	probably damaging	1.00
PIT4812001:Trank1	UTSW	9	111,347,912 (GRCm38)	missense	probably damaging	1.00
R0035:Trank1	UTSW	9	111,366,776 (GRCm38)	missense	probably benign	0.00
R0064:Trank1	UTSW	9	111,343,195 (GRCm38)	missense	probably damaging	1.00
R0064:Trank1	UTSW	9	111,343,195 (GRCm38)	missense	probably damaging	1.00
R0089:Trank1	UTSW	9	111,392,910 (GRCm38)	missense	probably benign	0.00
R0207:Trank1	UTSW	9	111,366,253 (GRCm38)	missense	probably damaging	1.00
R0255:Trank1	UTSW	9	111,366,024 (GRCm38)	missense	possibly damaging	0.92
R0334:Trank1	UTSW	9	111,392,940 (GRCm38)	missense	probably damaging	1.00
R0334:Trank1	UTSW	9	111,365,353 (GRCm38)	missense	probably benign	0.00
R0383:Trank1	UTSW	9	111,391,477 (GRCm38)	missense	probably benign	0.08
R0421:Trank1	UTSW	9	111,391,839 (GRCm38)	missense	probably damaging	1.00
R0494:Trank1	UTSW	9	111,391,293 (GRCm38)	missense	probably benign	0.19
R0518:Trank1	UTSW	9	111,333,808 (GRCm38)	missense	probably damaging	1.00
R0560:Trank1	UTSW	9	111,391,086 (GRCm38)	missense	possibly damaging	0.88
R0637:Trank1	UTSW	9	111,390,441 (GRCm38)	missense	probably damaging	1.00
R0731:Trank1	UTSW	9	111,365,488 (GRCm38)	missense	probably damaging	1.00
R0761:Trank1	UTSW	9	111,366,613 (GRCm38)	missense	probably damaging	1.00
R0766:Trank1	UTSW	9	111,347,469 (GRCm38)	missense	probably benign	0.45
R0827:Trank1	UTSW	9	111,349,417 (GRCm38)	unclassified	probably benign
R1005:Trank1	UTSW	9	111,333,721 (GRCm38)	missense	probably benign	0.13
R1108:Trank1	UTSW	9	111,365,307 (GRCm38)	missense	probably benign	0.00
R1155:Trank1	UTSW	9	111,366,970 (GRCm38)	missense	possibly damaging	0.95
R1470:Trank1	UTSW	9	111,343,232 (GRCm38)	missense	possibly damaging	0.91
R1470:Trank1	UTSW	9	111,343,232 (GRCm38)	missense	possibly damaging	0.91
R1596:Trank1	UTSW	9	111,366,290 (GRCm38)	missense	possibly damaging	0.93
R1601:Trank1	UTSW	9	111,373,477 (GRCm38)	missense	probably damaging	1.00
R1751:Trank1	UTSW	9	111,391,479 (GRCm38)	missense	probably benign
R1754:Trank1	UTSW	9	111,392,871 (GRCm38)	missense	probably benign	0.00
R1767:Trank1	UTSW	9	111,391,479 (GRCm38)	missense	probably benign
R1809:Trank1	UTSW	9	111,392,825 (GRCm38)	missense	probably benign	0.34
R1912:Trank1	UTSW	9	111,390,709 (GRCm38)	missense	probably benign	0.00
R1920:Trank1	UTSW	9	111,347,928 (GRCm38)	critical splice donor site	probably null
R1960:Trank1	UTSW	9	111,391,628 (GRCm38)	missense	probably damaging	1.00
R1993:Trank1	UTSW	9	111,378,832 (GRCm38)	missense	probably benign	0.20
R2012:Trank1	UTSW	9	111,365,028 (GRCm38)	missense	probably benign
R2025:Trank1	UTSW	9	111,392,039 (GRCm38)	missense	probably benign	0.01
R2050:Trank1	UTSW	9	111,364,788 (GRCm38)	missense	probably damaging	1.00
R2857:Trank1	UTSW	9	111,366,933 (GRCm38)	missense	probably benign	0.00
R2912:Trank1	UTSW	9	111,392,483 (GRCm38)	missense	probably damaging	0.98
R2962:Trank1	UTSW	9	111,352,080 (GRCm38)	missense	probably damaging	1.00
R3030:Trank1	UTSW	9	111,391,530 (GRCm38)	missense	possibly damaging	0.63
R3821:Trank1	UTSW	9	111,378,819 (GRCm38)	missense	probably damaging	1.00
R3822:Trank1	UTSW	9	111,378,819 (GRCm38)	missense	probably damaging	1.00
R3892:Trank1	UTSW	9	111,364,759 (GRCm38)	missense	probably benign	0.03
R4105:Trank1	UTSW	9	111,352,197 (GRCm38)	missense	probably damaging	1.00
R4166:Trank1	UTSW	9	111,373,524 (GRCm38)	nonsense	probably null
R4237:Trank1	UTSW	9	111,367,035 (GRCm38)	missense	probably benign	0.04
R4239:Trank1	UTSW	9	111,367,035 (GRCm38)	missense	probably benign	0.04
R4394:Trank1	UTSW	9	111,365,197 (GRCm38)	missense	possibly damaging	0.86
R4417:Trank1	UTSW	9	111,365,968 (GRCm38)	missense	probably benign	0.17
R4611:Trank1	UTSW	9	111,362,261 (GRCm38)	missense	probably damaging	1.00
R4694:Trank1	UTSW	9	111,392,061 (GRCm38)	missense	probably benign	0.40
R4731:Trank1	UTSW	9	111,390,410 (GRCm38)	missense	probably damaging	1.00
R4843:Trank1	UTSW	9	111,366,078 (GRCm38)	missense	probably benign	0.00
R4852:Trank1	UTSW	9	111,391,895 (GRCm38)	missense	possibly damaging	0.68
R4859:Trank1	UTSW	9	111,365,010 (GRCm38)	missense	probably benign	0.17
R4868:Trank1	UTSW	9	111,365,641 (GRCm38)	missense	probably damaging	1.00
R5080:Trank1	UTSW	9	111,389,221 (GRCm38)	missense	probably damaging	0.99
R5156:Trank1	UTSW	9	111,390,694 (GRCm38)	missense	probably damaging	1.00
R5174:Trank1	UTSW	9	111,365,559 (GRCm38)	missense	probably benign	0.00
R5234:Trank1	UTSW	9	111,386,467 (GRCm38)	missense	probably damaging	1.00
R5386:Trank1	UTSW	9	111,362,402 (GRCm38)	missense	probably benign	0.12
R5419:Trank1	UTSW	9	111,391,301 (GRCm38)	missense	probably damaging	1.00
R5435:Trank1	UTSW	9	111,391,890 (GRCm38)	missense	probably benign	0.00
R5444:Trank1	UTSW	9	111,392,958 (GRCm38)	missense	probably benign	0.04
R5543:Trank1	UTSW	9	111,366,112 (GRCm38)	missense	probably damaging	0.97
R5560:Trank1	UTSW	9	111,390,567 (GRCm38)	missense	probably damaging	1.00
R5772:Trank1	UTSW	9	111,366,676 (GRCm38)	missense	possibly damaging	0.86
R5774:Trank1	UTSW	9	111,391,226 (GRCm38)	missense	probably damaging	1.00
R5843:Trank1	UTSW	9	111,365,860 (GRCm38)	missense	possibly damaging	0.59
R5858:Trank1	UTSW	9	111,392,536 (GRCm38)	missense	probably benign
R5878:Trank1	UTSW	9	111,366,685 (GRCm38)	missense	possibly damaging	0.93
R5900:Trank1	UTSW	9	111,391,716 (GRCm38)	missense	probably damaging	1.00
R5917:Trank1	UTSW	9	111,362,417 (GRCm38)	missense	probably benign	0.38
R5954:Trank1	UTSW	9	111,365,133 (GRCm38)	missense	probably benign	0.13
R6041:Trank1	UTSW	9	111,377,796 (GRCm38)	missense	possibly damaging	0.94
R6112:Trank1	UTSW	9	111,391,737 (GRCm38)	missense	probably damaging	1.00
R6165:Trank1	UTSW	9	111,391,872 (GRCm38)	missense	probably benign	0.00
R6255:Trank1	UTSW	9	111,352,246 (GRCm38)	critical splice donor site	probably null
R6395:Trank1	UTSW	9	111,367,200 (GRCm38)	missense	probably damaging	1.00
R6567:Trank1	UTSW	9	111,347,521 (GRCm38)	missense	probably benign	0.02
R6644:Trank1	UTSW	9	111,364,834 (GRCm38)	missense	possibly damaging	0.85
R6724:Trank1	UTSW	9	111,365,916 (GRCm38)	missense	probably damaging	1.00
R6788:Trank1	UTSW	9	111,390,679 (GRCm38)	missense	probably damaging	1.00
R6831:Trank1	UTSW	9	111,377,899 (GRCm38)	missense	probably benign	0.00
R6934:Trank1	UTSW	9	111,373,090 (GRCm38)	missense	probably damaging	0.99
R7127:Trank1	UTSW	9	111,365,796 (GRCm38)	missense	possibly damaging	0.85
R7206:Trank1	UTSW	9	111,345,515 (GRCm38)	critical splice donor site	probably null
R7236:Trank1	UTSW	9	111,373,074 (GRCm38)	missense	possibly damaging	0.93
R7247:Trank1	UTSW	9	111,367,512 (GRCm38)	missense	probably damaging	1.00
R7292:Trank1	UTSW	9	111,377,870 (GRCm38)	missense	probably benign	0.02
R7310:Trank1	UTSW	9	111,367,126 (GRCm38)	missense	probably damaging	1.00
R7431:Trank1	UTSW	9	111,362,402 (GRCm38)	missense	probably benign	0.12
R7448:Trank1	UTSW	9	111,366,349 (GRCm38)	missense	probably benign	0.01
R7477:Trank1	UTSW	9	111,364,957 (GRCm38)	missense	probably benign	0.00
R7514:Trank1	UTSW	9	111,364,756 (GRCm38)	missense	probably damaging	1.00
R7595:Trank1	UTSW	9	111,365,991 (GRCm38)	missense	probably damaging	1.00
R7637:Trank1	UTSW	9	111,365,296 (GRCm38)	missense	possibly damaging	0.71
R7648:Trank1	UTSW	9	111,391,685 (GRCm38)	missense	probably benign
R7737:Trank1	UTSW	9	111,366,012 (GRCm38)	nonsense	probably null
R7784:Trank1	UTSW	9	111,364,103 (GRCm38)	missense	probably damaging	1.00
R7884:Trank1	UTSW	9	111,392,516 (GRCm38)	missense	probably benign
R7912:Trank1	UTSW	9	111,391,528 (GRCm38)	missense	probably benign	0.04
R7938:Trank1	UTSW	9	111,365,028 (GRCm38)	missense	probably benign
R7979:Trank1	UTSW	9	111,377,899 (GRCm38)	missense	probably benign	0.00
R8064:Trank1	UTSW	9	111,352,076 (GRCm38)	nonsense	probably null
R8100:Trank1	UTSW	9	111,392,793 (GRCm38)	missense	probably damaging	1.00
R8124:Trank1	UTSW	9	111,378,927 (GRCm38)	missense	probably benign	0.31
R8198:Trank1	UTSW	9	111,390,812 (GRCm38)	missense	probably benign	0.09
R8219:Trank1	UTSW	9	111,364,909 (GRCm38)	missense	probably damaging	1.00
R8223:Trank1	UTSW	9	111,365,889 (GRCm38)	missense	probably damaging	1.00
R8316:Trank1	UTSW	9	111,349,302 (GRCm38)	missense	probably benign	0.38
R8347:Trank1	UTSW	9	111,367,249 (GRCm38)	missense	probably damaging	1.00
R8436:Trank1	UTSW	9	111,391,382 (GRCm38)	missense	possibly damaging	0.86
R8489:Trank1	UTSW	9	111,390,275 (GRCm38)	missense	probably benign	0.01
R8682:Trank1	UTSW	9	111,365,344 (GRCm38)	missense	probably benign	0.01
R8768:Trank1	UTSW	9	111,389,276 (GRCm38)	missense	probably benign	0.00
R8770:Trank1	UTSW	9	111,390,824 (GRCm38)	missense	probably benign	0.00
R8829:Trank1	UTSW	9	111,347,523 (GRCm38)	missense	probably benign
R8838:Trank1	UTSW	9	111,364,905 (GRCm38)	missense	probably benign	0.03
R8855:Trank1	UTSW	9	111,312,221 (GRCm38)	missense	unknown
R8929:Trank1	UTSW	9	111,378,935 (GRCm38)	missense	possibly damaging	0.93
R9047:Trank1	UTSW	9	111,362,432 (GRCm38)	missense	probably damaging	0.99
R9090:Trank1	UTSW	9	111,345,479 (GRCm38)	missense	probably damaging	1.00
R9114:Trank1	UTSW	9	111,333,775 (GRCm38)	missense	probably damaging	1.00
R9133:Trank1	UTSW	9	111,391,702 (GRCm38)	missense	possibly damaging	0.93
R9177:Trank1	UTSW	9	111,392,511 (GRCm38)	missense	probably benign	0.00
R9178:Trank1	UTSW	9	111,367,200 (GRCm38)	missense	probably damaging	1.00
R9271:Trank1	UTSW	9	111,345,479 (GRCm38)	missense	probably damaging	1.00
R9314:Trank1	UTSW	9	111,365,981 (GRCm38)	missense	probably damaging	1.00
R9373:Trank1	UTSW	9	111,365,191 (GRCm38)	missense	probably benign	0.25
R9380:Trank1	UTSW	9	111,392,670 (GRCm38)	missense	probably benign	0.07
R9435:Trank1	UTSW	9	111,364,822 (GRCm38)	missense	probably benign	0.04
R9501:Trank1	UTSW	9	111,347,875 (GRCm38)	missense	probably benign	0.00
R9593:Trank1	UTSW	9	111,362,297 (GRCm38)	missense	probably benign	0.30
R9601:Trank1	UTSW	9	111,373,125 (GRCm38)	missense	probably benign	0.18
R9729:Trank1	UTSW	9	111,391,469 (GRCm38)	missense	probably damaging	1.00
X0064:Trank1	UTSW	9	111,343,236 (GRCm38)	missense	possibly damaging	0.57
Z1088:Trank1	UTSW	9	111,364,710 (GRCm38)	missense	probably damaging	0.99
Z1177:Trank1	UTSW	9	111,392,870 (GRCm38)	missense	possibly damaging	0.47
Z1177:Trank1	UTSW	9	111,367,377 (GRCm38)	missense	possibly damaging	0.83
Z1177:Trank1	UTSW	9	111,311,902 (GRCm38)	missense	unknown

Predicted Primers

PCR Primer
(F):5'- CAAAGCATTTGAGGGAACAGCCAC -3'
(R):5'- TGAGATATTGCTGGGATCTGCGAAC -3'

Sequencing Primer
(F):5'- GCTGATTTCCAGGGCTGAAC -3'
(R):5'- GGATCTGCGAACAGCCTTTTC -3'

Posted On

2014-05-23