Incidental Mutation 'R1756:Tpp2'
| ID |
194819 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tpp2
|
| Ensembl Gene |
ENSMUSG00000041763 |
| Gene Name |
tripeptidyl peptidase II |
| Synonyms |
TppII |
| MMRRC Submission |
039788-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.607)
|
| Stock # |
R1756 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
43973130-44042160 bp(+) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
T to A
at 44017885 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000139918
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000087933]
[ENSMUST00000188302]
[ENSMUST00000188313]
[ENSMUST00000189388]
[ENSMUST00000190207]
|
| AlphaFold |
Q64514 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000087933
|
| SMART Domains |
Protein: ENSMUSP00000085244
Gene: ENSMUSG00000041763
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Peptidase_S8
|
35 |
500 |
1.4e-96 |
PFAM |
|
low complexity region
|
674 |
685 |
N/A |
INTRINSIC |
|
Pfam:TPPII
|
777 |
964 |
2.4e-80 |
PFAM |
|
low complexity region
|
1017 |
1033 |
N/A |
INTRINSIC |
|
PDB:3LXU|X
|
1034 |
1262 |
1e-20 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000186441
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000188302
|
| SMART Domains |
Protein: ENSMUSP00000140474
Gene: ENSMUSG00000041763
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Peptidase_S8
|
39 |
509 |
4.3e-84 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000188313
|
| SMART Domains |
Protein: ENSMUSP00000139918
Gene: ENSMUSG00000041763
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Peptidase_S8
|
39 |
509 |
5.1e-83 |
PFAM |
|
low complexity region
|
674 |
685 |
N/A |
INTRINSIC |
|
Pfam:TPPII
|
773 |
966 |
2.7e-93 |
PFAM |
|
low complexity region
|
1004 |
1020 |
N/A |
INTRINSIC |
|
PDB:3LXU|X
|
1021 |
1249 |
1e-20 |
PDB |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189388
|
| SMART Domains |
Protein: ENSMUSP00000140562
Gene: ENSMUSG00000041763
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Peptidase_S8
|
39 |
509 |
2.3e-81 |
PFAM |
|
low complexity region
|
674 |
685 |
N/A |
INTRINSIC |
|
Pfam:TPPII
|
773 |
880 |
7.8e-49 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000190207
|
| SMART Domains |
Protein: ENSMUSP00000140313
Gene: ENSMUSG00000041763
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
86 |
N/A |
INTRINSIC |
|
PDB:3LXU|X
|
87 |
281 |
3e-19 |
PDB |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.5%
- 20x: 93.0%
|
| Validation Efficiency |
100% (96/96) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a mammalian peptidase that, at neutral pH, removes tripeptides from the N terminus of longer peptides. The protein has a specialized function that is essential for some MHC class I antigen presentation. The protein is a high molecular mass serine exopeptidase; the amino acid sequence surrounding the serine residue at the active site is similar to the peptidases of the subtilisin class rather than the trypsin class. [provided by RefSeq, Jul 2008]
PHENOTYPE: Engineered mutations of this gene result in decreased lifespan and symptoms of immunohematopoietic senescence. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A330008L17Rik |
C |
A |
8: 100,148,514 (GRCm39) |
|
noncoding transcript |
Het |
| Acin1 |
A |
G |
14: 54,902,661 (GRCm39) |
V377A |
probably benign |
Het |
| Adam39 |
A |
T |
8: 41,278,361 (GRCm39) |
I251F |
probably damaging |
Het |
| Adnp2 |
A |
T |
18: 80,170,912 (GRCm39) |
*1166K |
probably null |
Het |
| Akap12 |
T |
A |
10: 4,307,574 (GRCm39) |
D1461E |
probably benign |
Het |
| Aopep |
T |
A |
13: 63,215,875 (GRCm39) |
H382Q |
possibly damaging |
Het |
| Apba1 |
A |
G |
19: 23,871,056 (GRCm39) |
D296G |
possibly damaging |
Het |
| Apol7a |
G |
T |
15: 77,277,671 (GRCm39) |
L26M |
possibly damaging |
Het |
| Bcl2 |
C |
T |
1: 106,640,122 (GRCm39) |
M163I |
probably damaging |
Het |
| Cap2 |
T |
G |
13: 46,684,489 (GRCm39) |
I53R |
probably benign |
Het |
| Ccdc74a |
T |
C |
16: 17,468,332 (GRCm39) |
V318A |
possibly damaging |
Het |
| Ccnb2 |
A |
G |
9: 70,318,070 (GRCm39) |
V234A |
probably benign |
Het |
| Cd207 |
C |
T |
6: 83,652,579 (GRCm39) |
V184I |
probably benign |
Het |
| Cdk12 |
C |
A |
11: 98,132,587 (GRCm39) |
C1005* |
probably null |
Het |
| Cep83 |
T |
C |
10: 94,586,129 (GRCm39) |
S344P |
probably damaging |
Het |
| Ces1g |
A |
T |
8: 94,033,582 (GRCm39) |
Y447N |
probably benign |
Het |
| Cfap54 |
A |
T |
10: 92,883,923 (GRCm39) |
L277Q |
probably damaging |
Het |
| Cfh |
A |
G |
1: 140,028,615 (GRCm39) |
Y1027H |
probably damaging |
Het |
| Clcnkb |
T |
A |
4: 141,142,525 (GRCm39) |
I28F |
possibly damaging |
Het |
| Clec4d |
A |
G |
6: 123,244,068 (GRCm39) |
D59G |
probably damaging |
Het |
| Colq |
G |
A |
14: 31,269,409 (GRCm39) |
P153S |
probably damaging |
Het |
| Crybg1 |
T |
A |
10: 43,862,275 (GRCm39) |
T1500S |
probably damaging |
Het |
| Cyp2d34 |
T |
A |
15: 82,501,725 (GRCm39) |
R262W |
probably damaging |
Het |
| Dennd4b |
C |
G |
3: 90,178,912 (GRCm39) |
L559V |
probably damaging |
Het |
| Dhrs1 |
A |
G |
14: 55,976,766 (GRCm39) |
V306A |
probably benign |
Het |
| Diaph1 |
A |
T |
18: 37,987,626 (GRCm39) |
D1043E |
possibly damaging |
Het |
| Dis3 |
G |
T |
14: 99,323,539 (GRCm39) |
D538E |
probably damaging |
Het |
| Dnai2 |
T |
G |
11: 114,641,206 (GRCm39) |
S344A |
probably benign |
Het |
| Dner |
C |
T |
1: 84,423,311 (GRCm39) |
V431M |
probably damaging |
Het |
| Dnm1l |
A |
G |
16: 16,160,559 (GRCm39) |
|
probably null |
Het |
| Eps15 |
T |
G |
4: 109,170,115 (GRCm39) |
L139* |
probably null |
Het |
| Fam193a |
T |
A |
5: 34,623,636 (GRCm39) |
I55N |
possibly damaging |
Het |
| Gm10308 |
T |
A |
17: 91,396,385 (GRCm39) |
Y102* |
probably null |
Het |
| Gm10509 |
A |
G |
17: 21,909,762 (GRCm39) |
K30E |
possibly damaging |
Het |
| Gpr155 |
T |
C |
2: 73,197,921 (GRCm39) |
M400V |
probably benign |
Het |
| H2-M10.2 |
T |
C |
17: 36,597,015 (GRCm39) |
|
probably benign |
Het |
| Heatr1 |
G |
T |
13: 12,411,341 (GRCm39) |
A61S |
probably benign |
Het |
| Helb |
G |
T |
10: 119,930,147 (GRCm39) |
T744K |
probably damaging |
Het |
| Hmcn1 |
C |
A |
1: 150,474,781 (GRCm39) |
W4702L |
probably damaging |
Het |
| Hmcn2 |
C |
T |
2: 31,286,132 (GRCm39) |
R2095W |
probably damaging |
Het |
| Igfbp3 |
G |
C |
11: 7,158,461 (GRCm39) |
D267E |
probably damaging |
Het |
| Ighmbp2 |
T |
A |
19: 3,318,669 (GRCm39) |
H469L |
probably damaging |
Het |
| Kcnj3 |
A |
C |
2: 55,327,232 (GRCm39) |
K7T |
probably damaging |
Het |
| Krtap5-5 |
T |
G |
7: 141,783,358 (GRCm39) |
K97N |
unknown |
Het |
| Lcor |
T |
C |
19: 41,547,705 (GRCm39) |
S430P |
probably benign |
Het |
| Lpin1 |
A |
G |
12: 16,588,541 (GRCm39) |
V883A |
probably damaging |
Het |
| Lrp1b |
T |
C |
2: 41,000,837 (GRCm39) |
Y2243C |
probably damaging |
Het |
| Lrrc46 |
G |
A |
11: 96,925,556 (GRCm39) |
|
probably benign |
Het |
| Man1c1 |
G |
C |
4: 134,430,749 (GRCm39) |
P11R |
probably damaging |
Het |
| Mpdz |
C |
T |
4: 81,225,114 (GRCm39) |
V1438M |
possibly damaging |
Het |
| Muc21 |
A |
T |
17: 35,930,131 (GRCm39) |
|
probably benign |
Het |
| Ncbp1 |
T |
A |
4: 46,169,131 (GRCm39) |
L635* |
probably null |
Het |
| Nipbl |
T |
C |
15: 8,368,035 (GRCm39) |
N1202D |
possibly damaging |
Het |
| Nphs1 |
A |
G |
7: 30,160,959 (GRCm39) |
D196G |
probably benign |
Het |
| Nup58 |
A |
T |
14: 60,482,119 (GRCm39) |
|
probably benign |
Het |
| Or2b2b |
A |
G |
13: 21,858,865 (GRCm39) |
I83T |
probably benign |
Het |
| Or8b42 |
A |
T |
9: 38,342,291 (GRCm39) |
I238F |
probably benign |
Het |
| Or8k16 |
A |
G |
2: 85,520,427 (GRCm39) |
Y218C |
probably damaging |
Het |
| Pax8 |
A |
T |
2: 24,325,833 (GRCm39) |
N350K |
probably damaging |
Het |
| Pik3cd |
T |
C |
4: 149,743,207 (GRCm39) |
K298E |
probably benign |
Het |
| Pkd1 |
C |
T |
17: 24,813,459 (GRCm39) |
R4000C |
probably damaging |
Het |
| Pkn2 |
A |
T |
3: 142,516,488 (GRCm39) |
V546D |
possibly damaging |
Het |
| Plcg2 |
A |
G |
8: 118,319,447 (GRCm39) |
K673E |
probably benign |
Het |
| Pld4 |
T |
G |
12: 112,729,826 (GRCm39) |
|
probably null |
Het |
| Plek |
A |
T |
11: 16,942,901 (GRCm39) |
N130K |
probably damaging |
Het |
| Prune2 |
G |
A |
19: 17,101,068 (GRCm39) |
D2191N |
probably benign |
Het |
| Ptgis |
T |
C |
2: 167,048,723 (GRCm39) |
Y431C |
probably damaging |
Het |
| Rhbdf2 |
T |
C |
11: 116,498,092 (GRCm39) |
S36G |
probably benign |
Het |
| Rtn4ip1 |
C |
T |
10: 43,786,826 (GRCm39) |
A178V |
probably damaging |
Het |
| Rxfp1 |
A |
G |
3: 79,578,188 (GRCm39) |
S168P |
probably benign |
Het |
| Sec24a |
A |
G |
11: 51,624,590 (GRCm39) |
|
probably benign |
Het |
| Shf |
G |
A |
2: 122,199,163 (GRCm39) |
P51S |
probably damaging |
Het |
| Slitrk6 |
C |
T |
14: 110,987,984 (GRCm39) |
M574I |
probably benign |
Het |
| Slk |
T |
C |
19: 47,611,116 (GRCm39) |
F861L |
probably damaging |
Het |
| Smpd3 |
C |
A |
8: 106,991,603 (GRCm39) |
A317S |
probably benign |
Het |
| Spopfm1 |
A |
T |
3: 94,173,525 (GRCm39) |
M174L |
probably benign |
Het |
| Spz1 |
T |
A |
13: 92,711,633 (GRCm39) |
Q281L |
probably damaging |
Het |
| Syde1 |
T |
A |
10: 78,422,814 (GRCm39) |
R519S |
probably benign |
Het |
| Taf4 |
T |
C |
2: 179,618,324 (GRCm39) |
H39R |
unknown |
Het |
| Tbx5 |
A |
T |
5: 119,983,178 (GRCm39) |
|
probably null |
Het |
| Tektl1 |
T |
A |
10: 78,583,031 (GRCm39) |
K451M |
probably damaging |
Het |
| Tenm2 |
C |
T |
11: 35,954,004 (GRCm39) |
G1236R |
possibly damaging |
Het |
| Th |
G |
A |
7: 142,451,903 (GRCm39) |
Q19* |
probably null |
Het |
| Tmprss11a |
T |
A |
5: 86,568,038 (GRCm39) |
I230F |
probably damaging |
Het |
| Tnfrsf14 |
T |
A |
4: 155,009,779 (GRCm39) |
H50L |
possibly damaging |
Het |
| Trappc9 |
G |
A |
15: 72,897,816 (GRCm39) |
R377W |
probably damaging |
Het |
| Trim2 |
A |
G |
3: 84,098,107 (GRCm39) |
I398T |
possibly damaging |
Het |
| Trpc5 |
A |
T |
X: 143,264,222 (GRCm39) |
S212T |
probably damaging |
Het |
| Ttn |
A |
G |
2: 76,617,678 (GRCm39) |
|
probably benign |
Het |
| Unc80 |
A |
G |
1: 66,678,407 (GRCm39) |
T2063A |
possibly damaging |
Het |
| Usp37 |
A |
T |
1: 74,518,814 (GRCm39) |
S260T |
probably benign |
Het |
| Vcan |
A |
G |
13: 89,839,800 (GRCm39) |
S1915P |
probably benign |
Het |
| Vmn1r33 |
T |
A |
6: 66,589,282 (GRCm39) |
I91F |
possibly damaging |
Het |
| Zfp422 |
T |
C |
6: 116,603,385 (GRCm39) |
T205A |
probably benign |
Het |
|
| Other mutations in Tpp2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00977:Tpp2
|
APN |
1 |
44,022,451 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01021:Tpp2
|
APN |
1 |
43,973,347 (GRCm39) |
nonsense |
probably null |
|
|
IGL01096:Tpp2
|
APN |
1 |
44,000,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01344:Tpp2
|
APN |
1 |
44,022,422 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01642:Tpp2
|
APN |
1 |
43,993,813 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02719:Tpp2
|
APN |
1 |
43,979,391 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL02890:Tpp2
|
APN |
1 |
44,038,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Tpp2
|
APN |
1 |
43,995,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03175:Tpp2
|
APN |
1 |
44,012,671 (GRCm39) |
missense |
probably benign |
0.35 |
|
beaver
|
UTSW |
1 |
44,010,875 (GRCm39) |
missense |
probably benign |
0.08 |
|
billingsly
|
UTSW |
1 |
44,022,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
cleaver
|
UTSW |
1 |
44,017,668 (GRCm39) |
nonsense |
probably null |
|
|
dow
|
UTSW |
1 |
44,009,552 (GRCm39) |
splice site |
probably benign |
|
|
Eddie
|
UTSW |
1 |
44,008,148 (GRCm39) |
missense |
probably damaging |
1.00 |
|
jerry
|
UTSW |
1 |
44,017,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
June
|
UTSW |
1 |
43,993,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
landers
|
UTSW |
1 |
44,016,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
mathers
|
UTSW |
1 |
44,031,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
recurrentis
|
UTSW |
1 |
44,031,553 (GRCm39) |
missense |
probably null |
0.29 |
|
state
|
UTSW |
1 |
44,017,598 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
wally
|
UTSW |
1 |
44,031,556 (GRCm39) |
critical splice donor site |
probably null |
|
|
Ward
|
UTSW |
1 |
43,993,896 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
wilson
|
UTSW |
1 |
44,011,849 (GRCm39) |
critical splice donor site |
probably null |
|
|
BB010:Tpp2
|
UTSW |
1 |
44,000,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Tpp2
|
UTSW |
1 |
44,000,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0001:Tpp2
|
UTSW |
1 |
44,010,886 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0003:Tpp2
|
UTSW |
1 |
43,999,299 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0066:Tpp2
|
UTSW |
1 |
44,020,908 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0110:Tpp2
|
UTSW |
1 |
44,017,664 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0110:Tpp2
|
UTSW |
1 |
44,038,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0167:Tpp2
|
UTSW |
1 |
44,009,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0441:Tpp2
|
UTSW |
1 |
44,029,722 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0520:Tpp2
|
UTSW |
1 |
44,029,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0639:Tpp2
|
UTSW |
1 |
44,014,607 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1118:Tpp2
|
UTSW |
1 |
44,031,556 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1119:Tpp2
|
UTSW |
1 |
44,031,556 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1593:Tpp2
|
UTSW |
1 |
44,014,593 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1702:Tpp2
|
UTSW |
1 |
44,029,708 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2066:Tpp2
|
UTSW |
1 |
44,017,598 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R2171:Tpp2
|
UTSW |
1 |
43,996,606 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2378:Tpp2
|
UTSW |
1 |
44,038,925 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2394:Tpp2
|
UTSW |
1 |
44,022,346 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R2507:Tpp2
|
UTSW |
1 |
44,040,609 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2879:Tpp2
|
UTSW |
1 |
44,010,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3436:Tpp2
|
UTSW |
1 |
43,979,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4106:Tpp2
|
UTSW |
1 |
44,040,617 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4658:Tpp2
|
UTSW |
1 |
43,993,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4760:Tpp2
|
UTSW |
1 |
44,010,875 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4963:Tpp2
|
UTSW |
1 |
44,031,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tpp2
|
UTSW |
1 |
44,040,633 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5073:Tpp2
|
UTSW |
1 |
43,993,896 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6010:Tpp2
|
UTSW |
1 |
43,990,373 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6118:Tpp2
|
UTSW |
1 |
43,979,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6155:Tpp2
|
UTSW |
1 |
43,995,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6169:Tpp2
|
UTSW |
1 |
44,022,739 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6236:Tpp2
|
UTSW |
1 |
44,016,477 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6695:Tpp2
|
UTSW |
1 |
44,022,436 (GRCm39) |
missense |
probably benign |
|
|
R6845:Tpp2
|
UTSW |
1 |
44,017,668 (GRCm39) |
nonsense |
probably null |
|
|
R7054:Tpp2
|
UTSW |
1 |
44,022,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7094:Tpp2
|
UTSW |
1 |
44,008,148 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7223:Tpp2
|
UTSW |
1 |
44,008,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7316:Tpp2
|
UTSW |
1 |
44,009,591 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7324:Tpp2
|
UTSW |
1 |
44,017,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7363:Tpp2
|
UTSW |
1 |
44,024,582 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7454:Tpp2
|
UTSW |
1 |
43,993,819 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7496:Tpp2
|
UTSW |
1 |
44,022,677 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7699:Tpp2
|
UTSW |
1 |
44,009,626 (GRCm39) |
missense |
probably benign |
|
|
R7700:Tpp2
|
UTSW |
1 |
44,009,626 (GRCm39) |
missense |
probably benign |
|
|
R7804:Tpp2
|
UTSW |
1 |
44,022,441 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7933:Tpp2
|
UTSW |
1 |
44,000,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7979:Tpp2
|
UTSW |
1 |
43,979,297 (GRCm39) |
missense |
probably benign |
0.35 |
|
R8032:Tpp2
|
UTSW |
1 |
44,014,628 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8101:Tpp2
|
UTSW |
1 |
44,009,600 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8245:Tpp2
|
UTSW |
1 |
44,022,712 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8314:Tpp2
|
UTSW |
1 |
43,973,387 (GRCm39) |
missense |
probably benign |
0.10 |
|
R8518:Tpp2
|
UTSW |
1 |
44,019,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8519:Tpp2
|
UTSW |
1 |
44,016,365 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8529:Tpp2
|
UTSW |
1 |
44,022,300 (GRCm39) |
missense |
probably benign |
|
|
R8756:Tpp2
|
UTSW |
1 |
43,999,295 (GRCm39) |
nonsense |
probably null |
|
|
R8765:Tpp2
|
UTSW |
1 |
44,011,849 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8773:Tpp2
|
UTSW |
1 |
44,009,552 (GRCm39) |
splice site |
probably benign |
|
|
R8915:Tpp2
|
UTSW |
1 |
44,016,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9049:Tpp2
|
UTSW |
1 |
43,992,502 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9090:Tpp2
|
UTSW |
1 |
43,993,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9176:Tpp2
|
UTSW |
1 |
44,031,553 (GRCm39) |
missense |
probably null |
0.29 |
|
R9214:Tpp2
|
UTSW |
1 |
44,031,514 (GRCm39) |
missense |
probably benign |
|
|
R9271:Tpp2
|
UTSW |
1 |
43,993,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9316:Tpp2
|
UTSW |
1 |
44,017,604 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9371:Tpp2
|
UTSW |
1 |
43,999,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9422:Tpp2
|
UTSW |
1 |
44,017,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9488:Tpp2
|
UTSW |
1 |
44,041,272 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9513:Tpp2
|
UTSW |
1 |
44,017,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9514:Tpp2
|
UTSW |
1 |
44,017,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9516:Tpp2
|
UTSW |
1 |
44,017,648 (GRCm39) |
missense |
probably benign |
0.01 |
|
| Predicted Primers |
|
| Posted On |
2014-05-23 |
Incidental Mutation