Incidental Mutation 'R1757:Umodl1'
| ID |
195022 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Umodl1
|
| Ensembl Gene |
ENSMUSG00000054134 |
| Gene Name |
uromodulin-like 1 |
| Synonyms |
D17Ertd488e |
| MMRRC Submission |
039789-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1757 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
31173614-31229684 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 31227674 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 1336
(I1336F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000110202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066554]
[ENSMUST00000066981]
[ENSMUST00000114555]
|
| AlphaFold |
Q5DID3 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000066554
AA Change: I1336F
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000067443
Gene: ENSMUSG00000054134
AA Change: I1336F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000066981
AA Change: I1221F
|
| SMART Domains |
Protein: ENSMUSP00000065470
Gene: ENSMUSG00000054134
AA Change: I1221F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
8.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
8.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
619 |
632 |
N/A |
INTRINSIC |
|
SEA
|
706 |
821 |
8.88e-2 |
SMART |
|
EGF
|
818 |
859 |
4.26e0 |
SMART |
|
ZP
|
909 |
1152 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1186 |
1208 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000114555
AA Change: I1336F
PolyPhen 2
Score 0.985 (Sensitivity: 0.74; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000110202
Gene: ENSMUSG00000054134
AA Change: I1336F
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
22 |
N/A |
INTRINSIC |
|
Pfam:EMI
|
34 |
102 |
9.7e-13 |
PFAM |
|
WAP
|
118 |
159 |
3.15e-4 |
SMART |
|
EGF_like
|
265 |
306 |
3.72e-2 |
SMART |
|
FN3
|
305 |
381 |
2.61e0 |
SMART |
|
Pfam:SEA
|
388 |
492 |
9.9e-15 |
PFAM |
|
EGF
|
503 |
545 |
4.63e-1 |
SMART |
|
low complexity region
|
651 |
661 |
N/A |
INTRINSIC |
|
FN3
|
736 |
811 |
6.01e-5 |
SMART |
|
SEA
|
821 |
936 |
8.88e-2 |
SMART |
|
EGF
|
933 |
974 |
4.26e0 |
SMART |
|
ZP
|
1024 |
1267 |
5.44e-25 |
SMART |
|
transmembrane domain
|
1301 |
1323 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1113 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.4%
|
| Validation Efficiency |
100% (111/111) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 108 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abhd6 |
A |
T |
14: 8,049,867 (GRCm38) |
I219F |
probably damaging |
Het |
| Acvr1b |
A |
G |
15: 101,096,703 (GRCm39) |
I207V |
possibly damaging |
Het |
| Adamtsl4 |
T |
C |
3: 95,585,252 (GRCm39) |
T839A |
probably benign |
Het |
| Akap1 |
C |
T |
11: 88,736,578 (GRCm39) |
R61H |
probably damaging |
Het |
| Akap9 |
A |
G |
5: 4,051,667 (GRCm39) |
D1478G |
probably benign |
Het |
| Aloxe3 |
T |
A |
11: 69,026,775 (GRCm39) |
V547E |
possibly damaging |
Het |
| Ano6 |
G |
A |
15: 95,860,148 (GRCm39) |
A757T |
probably damaging |
Het |
| Armc10 |
A |
G |
5: 21,858,455 (GRCm39) |
T167A |
probably damaging |
Het |
| BB019430 |
A |
C |
10: 58,539,869 (GRCm39) |
|
noncoding transcript |
Het |
| Brms1 |
C |
T |
19: 5,096,435 (GRCm39) |
R82W |
probably damaging |
Het |
| Btnl6 |
G |
A |
17: 34,733,062 (GRCm39) |
T267I |
probably benign |
Het |
| Catsper4 |
A |
T |
4: 133,945,212 (GRCm39) |
F215L |
probably benign |
Het |
| Ccdc188 |
T |
C |
16: 18,036,552 (GRCm39) |
F197S |
probably damaging |
Het |
| Cers5 |
A |
C |
15: 99,634,212 (GRCm39) |
C379G |
probably benign |
Het |
| Chchd6 |
A |
G |
6: 89,361,626 (GRCm39) |
L259P |
probably damaging |
Het |
| Cntnap2 |
T |
A |
6: 46,736,763 (GRCm39) |
C730S |
probably damaging |
Het |
| Coch |
T |
G |
12: 51,649,631 (GRCm39) |
V314G |
probably damaging |
Het |
| Cog1 |
T |
A |
11: 113,543,130 (GRCm39) |
S213T |
possibly damaging |
Het |
| Crot |
A |
T |
5: 9,037,828 (GRCm39) |
F163I |
probably damaging |
Het |
| Cyp4f13 |
A |
T |
17: 33,148,932 (GRCm39) |
I162N |
probably damaging |
Het |
| Dab2 |
A |
T |
15: 6,359,933 (GRCm39) |
|
probably benign |
Het |
| Depdc1b |
C |
T |
13: 108,460,482 (GRCm39) |
R31W |
probably damaging |
Het |
| Dlk1 |
T |
C |
12: 109,425,613 (GRCm39) |
F161S |
probably damaging |
Het |
| Dnah6 |
T |
C |
6: 73,137,965 (GRCm39) |
E913G |
probably damaging |
Het |
| Dnajc6 |
A |
G |
4: 101,455,028 (GRCm39) |
Y5C |
probably damaging |
Het |
| Dock10 |
T |
C |
1: 80,511,586 (GRCm39) |
T1508A |
probably damaging |
Het |
| Dstyk |
A |
G |
1: 132,361,832 (GRCm39) |
|
probably benign |
Het |
| Efcc1 |
T |
C |
6: 87,726,265 (GRCm39) |
|
probably benign |
Het |
| Entpd1 |
T |
C |
19: 40,727,450 (GRCm39) |
Y533H |
probably benign |
Het |
| Epha8 |
A |
T |
4: 136,658,789 (GRCm39) |
|
probably null |
Het |
| Erich3 |
C |
T |
3: 154,401,402 (GRCm39) |
T17M |
probably damaging |
Het |
| Ethe1 |
T |
C |
7: 24,307,899 (GRCm39) |
|
probably benign |
Het |
| Fbxw15 |
A |
T |
9: 109,386,347 (GRCm39) |
M211K |
probably damaging |
Het |
| Fhod3 |
G |
A |
18: 25,199,335 (GRCm39) |
V669M |
possibly damaging |
Het |
| Fktn |
C |
T |
4: 53,747,003 (GRCm39) |
|
probably benign |
Het |
| Foxred1 |
G |
A |
9: 35,122,130 (GRCm39) |
R20C |
probably benign |
Het |
| Gbp9 |
A |
G |
5: 105,242,319 (GRCm39) |
L140P |
probably damaging |
Het |
| Gga1 |
T |
C |
15: 78,773,230 (GRCm39) |
L286P |
probably damaging |
Het |
| Gml |
T |
C |
15: 74,685,462 (GRCm39) |
|
probably benign |
Het |
| Gsap |
A |
T |
5: 21,486,035 (GRCm39) |
K628N |
probably damaging |
Het |
| Gtf3c4 |
G |
A |
2: 28,720,648 (GRCm39) |
|
probably benign |
Het |
| H2-M10.6 |
A |
C |
17: 37,124,043 (GRCm39) |
Y169S |
probably benign |
Het |
| Hal |
G |
A |
10: 93,330,490 (GRCm39) |
V245I |
probably benign |
Het |
| Hebp2 |
T |
C |
10: 18,420,849 (GRCm39) |
Y72C |
probably damaging |
Het |
| Helz2 |
T |
C |
2: 180,878,056 (GRCm39) |
E914G |
probably damaging |
Het |
| Herc3 |
T |
C |
6: 58,893,455 (GRCm39) |
Y906H |
probably damaging |
Het |
| Hfm1 |
A |
T |
5: 107,028,226 (GRCm39) |
|
probably null |
Het |
| Hgs |
C |
T |
11: 120,370,889 (GRCm39) |
P582S |
probably damaging |
Het |
| Hoxa10 |
G |
A |
6: 52,211,469 (GRCm39) |
P149L |
probably damaging |
Het |
| Inpp5j |
T |
A |
11: 3,454,738 (GRCm39) |
Q4L |
possibly damaging |
Het |
| Ints8 |
A |
C |
4: 11,254,109 (GRCm39) |
M1R |
probably null |
Het |
| Isg15 |
T |
C |
4: 156,284,447 (GRCm39) |
E27G |
possibly damaging |
Het |
| Klf13 |
A |
T |
7: 63,541,513 (GRCm39) |
C205S |
probably damaging |
Het |
| Lama1 |
A |
T |
17: 68,070,831 (GRCm39) |
Y830F |
probably benign |
Het |
| Lama1 |
G |
A |
17: 68,004,378 (GRCm39) |
V17M |
unknown |
Het |
| Lama3 |
A |
G |
18: 12,598,556 (GRCm39) |
N988D |
probably benign |
Het |
| Lcat |
CAT |
C |
8: 106,668,446 (GRCm39) |
|
probably null |
Het |
| Lct |
G |
T |
1: 128,228,994 (GRCm39) |
P833H |
probably damaging |
Het |
| Lmf1 |
A |
T |
17: 25,874,184 (GRCm39) |
R403W |
probably damaging |
Het |
| Me3 |
T |
G |
7: 89,282,230 (GRCm39) |
S38A |
probably benign |
Het |
| Myg1 |
A |
T |
15: 102,240,264 (GRCm39) |
D30V |
probably benign |
Het |
| Nbea |
A |
G |
3: 55,537,610 (GRCm39) |
I2841T |
possibly damaging |
Het |
| Nek1 |
T |
A |
8: 61,542,847 (GRCm39) |
|
probably null |
Het |
| Obsl1 |
C |
T |
1: 75,470,527 (GRCm39) |
R1043H |
probably benign |
Het |
| Or4p23 |
G |
T |
2: 88,576,361 (GRCm39) |
D290E |
probably benign |
Het |
| Or5b119 |
A |
C |
19: 13,456,971 (GRCm39) |
V197G |
possibly damaging |
Het |
| Or6n2 |
A |
T |
1: 173,897,224 (GRCm39) |
Y120F |
probably damaging |
Het |
| Or9m2 |
T |
G |
2: 87,820,926 (GRCm39) |
I157R |
probably damaging |
Het |
| Osbpl9 |
A |
G |
4: 108,921,780 (GRCm39) |
Y613H |
probably damaging |
Het |
| Per3 |
C |
T |
4: 151,127,249 (GRCm39) |
|
probably null |
Het |
| Pex6 |
G |
T |
17: 47,034,424 (GRCm39) |
V758L |
probably damaging |
Het |
| Pikfyve |
A |
G |
1: 65,291,707 (GRCm39) |
I1309V |
probably damaging |
Het |
| Pimreg |
A |
G |
11: 71,933,985 (GRCm39) |
E37G |
possibly damaging |
Het |
| Pjvk |
G |
A |
2: 76,486,232 (GRCm39) |
V211I |
probably benign |
Het |
| Plekhg4 |
T |
A |
8: 106,108,293 (GRCm39) |
V1112E |
probably damaging |
Het |
| Ptprz1 |
T |
A |
6: 23,044,319 (GRCm39) |
M2106K |
probably damaging |
Het |
| Rdh16f2 |
G |
T |
10: 127,712,765 (GRCm39) |
L254F |
probably benign |
Het |
| Rictor |
G |
A |
15: 6,803,343 (GRCm39) |
R485Q |
possibly damaging |
Het |
| Rnf146 |
G |
A |
10: 29,223,475 (GRCm39) |
T137M |
probably damaging |
Het |
| Rrp9 |
T |
A |
9: 106,360,203 (GRCm39) |
C204S |
probably damaging |
Het |
| Rxylt1 |
T |
C |
10: 121,924,920 (GRCm39) |
T261A |
probably benign |
Het |
| Serpinb9h |
T |
C |
13: 33,583,336 (GRCm39) |
S150P |
probably benign |
Het |
| Shkbp1 |
T |
C |
7: 27,041,776 (GRCm39) |
T693A |
probably benign |
Het |
| Skint9 |
A |
G |
4: 112,271,159 (GRCm39) |
Y84H |
probably benign |
Het |
| Slc22a12 |
A |
T |
19: 6,586,761 (GRCm39) |
|
probably null |
Het |
| Slfn4 |
T |
C |
11: 83,076,211 (GRCm39) |
C26R |
possibly damaging |
Het |
| Snrnp200 |
T |
C |
2: 127,074,363 (GRCm39) |
L1401P |
probably damaging |
Het |
| Specc1 |
T |
A |
11: 62,010,110 (GRCm39) |
|
probably null |
Het |
| Spef2 |
A |
T |
15: 9,717,568 (GRCm39) |
M316K |
probably damaging |
Het |
| Tbc1d22b |
A |
G |
17: 29,790,647 (GRCm39) |
R204G |
probably damaging |
Het |
| Tektl1 |
T |
C |
10: 78,583,058 (GRCm39) |
N442S |
probably benign |
Het |
| Tgfbr3l |
C |
A |
8: 4,299,548 (GRCm39) |
D110E |
probably benign |
Het |
| Ticrr |
T |
G |
7: 79,325,071 (GRCm39) |
S532R |
probably damaging |
Het |
| Ticrr |
C |
A |
7: 79,328,794 (GRCm39) |
Y644* |
probably null |
Het |
| Traf3ip1 |
A |
T |
1: 91,450,579 (GRCm39) |
T509S |
probably damaging |
Het |
| Trmt10b |
T |
C |
4: 45,307,946 (GRCm39) |
Y209H |
probably damaging |
Het |
| Trmt6 |
T |
C |
2: 132,652,157 (GRCm39) |
M172V |
probably damaging |
Het |
| Tsc1 |
A |
G |
2: 28,576,125 (GRCm39) |
D978G |
probably benign |
Het |
| Tshz2 |
C |
A |
2: 169,725,843 (GRCm39) |
F146L |
probably benign |
Het |
| Tspyl4 |
G |
T |
10: 34,173,576 (GRCm39) |
E23* |
probably null |
Het |
| Ulk2 |
A |
T |
11: 61,732,165 (GRCm39) |
|
probably benign |
Het |
| Vezt |
T |
C |
10: 93,806,425 (GRCm39) |
D662G |
probably benign |
Het |
| Vnn1 |
G |
T |
10: 23,776,727 (GRCm39) |
Q359H |
probably benign |
Het |
| Vnn1 |
A |
T |
10: 23,776,726 (GRCm39) |
Q359L |
possibly damaging |
Het |
| Zdhhc16 |
A |
G |
19: 41,930,394 (GRCm39) |
N14S |
probably damaging |
Het |
| Zfp455 |
T |
C |
13: 67,355,601 (GRCm39) |
S225P |
probably damaging |
Het |
| Zfp74 |
T |
A |
7: 29,634,486 (GRCm39) |
E407D |
probably benign |
Het |
| Zic2 |
T |
A |
14: 122,716,031 (GRCm39) |
H384Q |
possibly damaging |
Het |
|
| Other mutations in Umodl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00915:Umodl1
|
APN |
17 |
31,227,724 (GRCm39) |
utr 3 prime |
probably benign |
|
|
IGL01344:Umodl1
|
APN |
17 |
31,215,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01529:Umodl1
|
APN |
17 |
31,215,233 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
IGL01609:Umodl1
|
APN |
17 |
31,217,800 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01625:Umodl1
|
APN |
17 |
31,215,229 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01877:Umodl1
|
APN |
17 |
31,201,294 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01977:Umodl1
|
APN |
17 |
31,192,742 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02063:Umodl1
|
APN |
17 |
31,206,888 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02160:Umodl1
|
APN |
17 |
31,205,091 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02252:Umodl1
|
APN |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02427:Umodl1
|
APN |
17 |
31,187,415 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Umodl1
|
APN |
17 |
31,217,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02633:Umodl1
|
APN |
17 |
31,208,462 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03271:Umodl1
|
APN |
17 |
31,205,473 (GRCm39) |
nonsense |
probably null |
|
|
IGL03392:Umodl1
|
APN |
17 |
31,215,329 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Disquieting
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
floored
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7231_umodl1_507
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
surprising
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
unsettling
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
G1citation:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
PIT4468001:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0048:Umodl1
|
UTSW |
17 |
31,187,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0653:Umodl1
|
UTSW |
17 |
31,203,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0831:Umodl1
|
UTSW |
17 |
31,215,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1078:Umodl1
|
UTSW |
17 |
31,178,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1166:Umodl1
|
UTSW |
17 |
31,221,772 (GRCm39) |
splice site |
probably benign |
|
|
R1231:Umodl1
|
UTSW |
17 |
31,178,252 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1459:Umodl1
|
UTSW |
17 |
31,205,478 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1459:Umodl1
|
UTSW |
17 |
31,201,232 (GRCm39) |
splice site |
probably benign |
|
|
R1510:Umodl1
|
UTSW |
17 |
31,178,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1654:Umodl1
|
UTSW |
17 |
31,206,942 (GRCm39) |
missense |
probably benign |
|
|
R1781:Umodl1
|
UTSW |
17 |
31,187,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1873:Umodl1
|
UTSW |
17 |
31,201,238 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Umodl1
|
UTSW |
17 |
31,211,128 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R1917:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1918:Umodl1
|
UTSW |
17 |
31,203,017 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2057:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2058:Umodl1
|
UTSW |
17 |
31,227,740 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2089:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2091:Umodl1
|
UTSW |
17 |
31,190,893 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2431:Umodl1
|
UTSW |
17 |
31,211,062 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2903:Umodl1
|
UTSW |
17 |
31,211,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3032:Umodl1
|
UTSW |
17 |
31,208,502 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3956:Umodl1
|
UTSW |
17 |
31,221,837 (GRCm39) |
missense |
probably benign |
0.10 |
|
R3975:Umodl1
|
UTSW |
17 |
31,203,763 (GRCm39) |
nonsense |
probably null |
|
|
R4207:Umodl1
|
UTSW |
17 |
31,178,341 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4287:Umodl1
|
UTSW |
17 |
31,207,039 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4452:Umodl1
|
UTSW |
17 |
31,213,789 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4684:Umodl1
|
UTSW |
17 |
31,217,088 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4769:Umodl1
|
UTSW |
17 |
31,202,976 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4887:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4888:Umodl1
|
UTSW |
17 |
31,218,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4978:Umodl1
|
UTSW |
17 |
31,205,055 (GRCm39) |
missense |
probably benign |
|
|
R4993:Umodl1
|
UTSW |
17 |
31,205,459 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5241:Umodl1
|
UTSW |
17 |
31,203,066 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5254:Umodl1
|
UTSW |
17 |
31,199,333 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5454:Umodl1
|
UTSW |
17 |
31,205,439 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R5456:Umodl1
|
UTSW |
17 |
31,201,263 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5754:Umodl1
|
UTSW |
17 |
31,213,761 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6189:Umodl1
|
UTSW |
17 |
31,215,256 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6222:Umodl1
|
UTSW |
17 |
31,221,866 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6289:Umodl1
|
UTSW |
17 |
31,201,325 (GRCm39) |
missense |
probably benign |
0.16 |
|
R6432:Umodl1
|
UTSW |
17 |
31,205,121 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6478:Umodl1
|
UTSW |
17 |
31,178,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6702:Umodl1
|
UTSW |
17 |
31,205,273 (GRCm39) |
splice site |
probably null |
|
|
R6822:Umodl1
|
UTSW |
17 |
31,205,528 (GRCm39) |
nonsense |
probably null |
|
|
R6999:Umodl1
|
UTSW |
17 |
31,218,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7067:Umodl1
|
UTSW |
17 |
31,201,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7123:Umodl1
|
UTSW |
17 |
31,201,318 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Umodl1
|
UTSW |
17 |
31,201,236 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7231:Umodl1
|
UTSW |
17 |
31,205,090 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7234:Umodl1
|
UTSW |
17 |
31,205,595 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7297:Umodl1
|
UTSW |
17 |
31,227,639 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7392:Umodl1
|
UTSW |
17 |
31,201,306 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7401:Umodl1
|
UTSW |
17 |
31,217,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7461:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7594:Umodl1
|
UTSW |
17 |
31,173,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7613:Umodl1
|
UTSW |
17 |
31,207,031 (GRCm39) |
nonsense |
probably null |
|
|
R7763:Umodl1
|
UTSW |
17 |
31,205,430 (GRCm39) |
missense |
probably benign |
0.24 |
|
R7797:Umodl1
|
UTSW |
17 |
31,178,125 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7832:Umodl1
|
UTSW |
17 |
31,192,666 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7954:Umodl1
|
UTSW |
17 |
31,205,361 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8088:Umodl1
|
UTSW |
17 |
31,192,770 (GRCm39) |
missense |
probably benign |
0.29 |
|
R8111:Umodl1
|
UTSW |
17 |
31,190,792 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8314:Umodl1
|
UTSW |
17 |
31,203,806 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8826:Umodl1
|
UTSW |
17 |
31,202,958 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9067:Umodl1
|
UTSW |
17 |
31,192,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9091:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9099:Umodl1
|
UTSW |
17 |
31,178,147 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9270:Umodl1
|
UTSW |
17 |
31,185,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9341:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9343:Umodl1
|
UTSW |
17 |
31,217,701 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9400:Umodl1
|
UTSW |
17 |
31,215,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9569:Umodl1
|
UTSW |
17 |
31,217,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9615:Umodl1
|
UTSW |
17 |
31,217,152 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R9787:Umodl1
|
UTSW |
17 |
31,178,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GATGCATAATTCCCCTGACCCTGAC -3'
(R):5'- ATGGCAGAACTCTTTGCTGACCTAC -3'
Sequencing Primer
(F):5'- TGACACCTCTCTTACCCTGAAAC -3'
(R):5'- TGCTGACCTACAAATGGTCC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation