Mutagenetix > Incidental Mutation

Incidental Mutation 'R1784:Tbc1d31'

196073

Institutional Source

Beutler Lab

Gene Symbol

Tbc1d31

Ensembl Gene

ENSMUSG00000022364

Gene Name

TBC1 domain family, member 31

Synonyms

Wdr67, LOC210544, D330013L20Rik

MMRRC Submission

039815-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R1784 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

57775595-57833463 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 57827316 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Histidine to Glutamine at position 919 (H919Q)

Ref Sequence

ENSEMBL: ENSMUSP00000022992 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000022992]

AlphaFold

Q6NXY1

Predicted Effect

possibly damaging
Transcript: ENSMUST00000022992
AA Change: H919Q

PolyPhen 2 Score 0.861 (Sensitivity: 0.83; Specificity: 0.93)

SMART Domains

Protein: ENSMUSP00000022992
Gene: ENSMUSG00000022364
AA Change: H919Q

Domain	Start	End	E-Value	Type
WD40	39	70	3.3e1	SMART
WD40	72	112	7.64e1	SMART
WD40	115	153	1.42e-4	SMART
WD40	156	196	1.03e1	SMART
WD40	199	242	6.6e1	SMART
Blast:WD40	245	292	8e-23	BLAST
WD40	295	334	2.48e0	SMART
Pfam:RabGAP-TBC	427	619	9.5e-11	PFAM
coiled coil region	699	844	N/A	INTRINSIC
low complexity region	893	906	N/A	INTRINSIC
low complexity region	974	985	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000110175

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000159801

Predicted Effect

unknown
Transcript: ENSMUST00000161329
AA Change: H156Q

SMART Domains

Protein: ENSMUSP00000124466
Gene: ENSMUSG00000022364
AA Change: H156Q

Domain	Start	End	E-Value	Type
coiled coil region	97	124	N/A	INTRINSIC
low complexity region	131	144	N/A	INTRINSIC
low complexity region	212	223	N/A	INTRINSIC

Coding Region Coverage

1x: 97.5%
3x: 97.0%
10x: 95.5%
20x: 93.2%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 193 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930453N24Rik	T	C	16: 64,589,385 (GRCm39)	I90V	probably damaging	Het
Acacb	TGGGG	TGGG	5: 114,347,828 (GRCm39)		probably null	Het
Adamts17	C	T	7: 66,799,704 (GRCm39)	R1060*	probably null	Het
Adamts5	T	A	16: 85,674,803 (GRCm39)	K454*	probably null	Het
Adgrg6	T	C	10: 14,315,526 (GRCm39)	T593A	probably damaging	Het
Aldh4a1	A	G	4: 139,371,472 (GRCm39)	Y462C	probably damaging	Het
Ankrd12	G	T	17: 66,291,071 (GRCm39)	P1454Q	probably benign	Het
Ap1m1	T	A	8: 73,006,693 (GRCm39)	S230T	probably benign	Het
Aspm	A	G	1: 139,401,312 (GRCm39)	I1111V	probably benign	Het
Atp6ap1l	T	A	13: 91,053,400 (GRCm39)	K4N	probably damaging	Het
Boc	T	C	16: 44,316,782 (GRCm39)	T454A	probably benign	Het
Bola1	C	T	3: 96,104,426 (GRCm39)	G56D	probably benign	Het
C4bp	C	G	1: 130,570,725 (GRCm39)	V284L	probably benign	Het
Cacna1s	T	C	1: 136,046,454 (GRCm39)	F1761S	probably benign	Het
Camsap2	C	T	1: 136,209,053 (GRCm39)	R802Q	probably benign	Het
Capn9	G	A	8: 125,332,450 (GRCm39)	G430R	possibly damaging	Het
Cbs	G	T	17: 31,839,923 (GRCm39)	A337E	probably benign	Het
Ccdc186	A	C	19: 56,797,652 (GRCm39)	H306Q	probably benign	Het
Cd180	T	C	13: 102,842,367 (GRCm39)	L471P	probably damaging	Het
Cd55	C	A	1: 130,387,370 (GRCm39)	A143S	probably benign	Het
Cd55	C	T	1: 130,377,160 (GRCm39)	V333I	probably benign	Het
Cdk12	T	C	11: 98,140,796 (GRCm39)		probably benign	Het
Cfh	C	T	1: 140,075,435 (GRCm39)	V268I	possibly damaging	Het
Cfhr2	A	G	1: 139,741,180 (GRCm39)	M265T	probably benign	Het
Cfhr2	A	C	1: 139,741,197 (GRCm39)	N259K	probably benign	Het
Chi3l1	C	T	1: 134,116,267 (GRCm39)	A250V	probably damaging	Het
Chit1	A	G	1: 134,077,132 (GRCm39)	R312G	possibly damaging	Het
Chrna6	A	T	8: 27,896,812 (GRCm39)	M355K	possibly damaging	Het
Clcn1	T	A	6: 42,276,448 (GRCm39)	F360Y	possibly damaging	Het
Copa	T	A	1: 171,939,554 (GRCm39)	F597Y	probably benign	Het
Crb1	G	A	1: 139,168,876 (GRCm39)	P881S	probably damaging	Het
Crb1	C	T	1: 139,170,733 (GRCm39)	G825R	probably damaging	Het
Crb1	C	T	1: 139,171,155 (GRCm39)	R684H	probably benign	Het
Crb1	T	C	1: 139,162,517 (GRCm39)	M1214V	probably benign	Het
Crb1	A	T	1: 139,165,360 (GRCm39)	H921Q	probably benign	Het
Crybg1	T	A	10: 43,880,015 (GRCm39)	Q391L	probably damaging	Het
Cwh43	T	C	5: 73,565,561 (GRCm39)	L42P	probably damaging	Het
Cxcr4	C	T	1: 128,517,014 (GRCm39)	V216I	probably benign	Het
Cyb5r1	C	T	1: 134,335,405 (GRCm39)	R147W	probably damaging	Het
Ddx59	T	C	1: 136,344,791 (GRCm39)	V154A	probably benign	Het
Dnah17	C	T	11: 117,960,345 (GRCm39)	C2572Y	possibly damaging	Het
Dnah9	G	A	11: 65,975,846 (GRCm39)	T1401I	possibly damaging	Het
Dstyk	C	T	1: 132,384,722 (GRCm39)	L739F	probably damaging	Het
Elf2	A	T	3: 51,164,993 (GRCm39)	V277D	probably damaging	Het
Etnk2	C	A	1: 133,293,325 (GRCm39)	D89E	probably benign	Het
Etnk2	G	T	1: 133,293,503 (GRCm39)	G149W	probably damaging	Het
Etnk2	C	T	1: 133,293,554 (GRCm39)	R166*	probably null	Het
Etnk2	G	A	1: 133,293,555 (GRCm39)	R166Q	probably benign	Het
Etnk2	T	A	1: 133,304,653 (GRCm39)	V292E	probably benign	Het
Etnk2	G	T	1: 133,304,784 (GRCm39)	A336S	probably benign	Het
Etnk2	C	T	1: 133,291,628 (GRCm39)	P43S	probably benign	Het
Fam72a	C	T	1: 131,466,633 (GRCm39)	T139M	probably benign	Het
Fam72a	T	C	1: 131,458,406 (GRCm39)	I56T	probably benign	Het
Fat3	A	C	9: 15,907,611 (GRCm39)	V2797G	possibly damaging	Het
Fbxl6	C	T	15: 76,422,258 (GRCm39)	R137H	probably damaging	Het
Fcamr	A	G	1: 130,739,317 (GRCm39)	I206V	probably benign	Het
Fcamr	G	A	1: 130,740,366 (GRCm39)	G262S	probably benign	Het
Fcamr	A	G	1: 130,740,429 (GRCm39)	I283V	probably benign	Het
Fcamr	T	C	1: 130,740,475 (GRCm39)	V298A	probably benign	Het
Fcamr	A	G	1: 130,740,546 (GRCm39)	M322V	probably benign	Het
Fcamr	C	T	1: 130,740,553 (GRCm39)	P324L	probably benign	Het
Fcamr	A	G	1: 130,742,334 (GRCm39)	N574D	probably benign	Het
Fcamr	A	C	1: 130,732,364 (GRCm39)	N117T	probably benign	Het
Fcmr	T	C	1: 130,806,006 (GRCm39)	S321P	probably benign	Het
Fcmr	A	G	1: 130,803,711 (GRCm39)	T172A	probably benign	Het
Gabarap	C	T	11: 69,882,515 (GRCm39)		probably benign	Het
Galnt17	A	T	5: 131,179,801 (GRCm39)	H115Q	probably benign	Het
Gemin4	G	C	11: 76,101,876 (GRCm39)	P962A	probably damaging	Het
Glrx2	C	T	1: 143,615,478 (GRCm39)	A27V	possibly damaging	Het
Gm10563	C	T	4: 155,720,337 (GRCm39)		probably benign	Het
Gm12887	T	A	4: 121,473,715 (GRCm39)	D45V	probably benign	Het
Gse1	G	A	8: 121,294,992 (GRCm39)		probably benign	Het
Guk1	A	T	11: 59,076,138 (GRCm39)	V100E	probably damaging	Het
Heatr4	T	C	12: 84,014,346 (GRCm39)	I630M	probably benign	Het
Hectd4	A	T	5: 121,439,902 (GRCm39)	Y1134F	possibly damaging	Het
Ift20	G	A	11: 78,430,860 (GRCm39)	E68K	probably damaging	Het
Igfn1	G	A	1: 135,887,666 (GRCm39)	P2466L	probably damaging	Het
Igfn1	T	C	1: 135,926,421 (GRCm39)	I10V	unknown	Het
Igfn1	T	C	1: 135,926,363 (GRCm39)	E29G	probably benign	Het
Igfn1	G	A	1: 135,910,213 (GRCm39)	R124W	probably benign	Het
Igfn1	C	T	1: 135,907,653 (GRCm39)	A231T	probably benign	Het
Igfn1	C	T	1: 135,899,865 (GRCm39)	R482Q	probably benign	Het
Igfn1	T	C	1: 135,898,149 (GRCm39)	S806G	probably benign	Het
Igfn1	G	A	1: 135,895,937 (GRCm39)	A1543V	probably benign	Het
Ikbke	C	A	1: 131,193,674 (GRCm39)	A459S	probably benign	Het
Ikbke	T	C	1: 131,197,560 (GRCm39)	S447G	probably benign	Het
Ipo9	A	G	1: 135,329,988 (GRCm39)	V484A	probably benign	Het
Ipo9	ATCCTCCTCCTCCTCCTC	ATCCTCCTCCTCCTCCTCCTC	1: 135,314,006 (GRCm39)		probably benign	Het
Itprid1	T	C	6: 55,945,526 (GRCm39)	F749S	probably benign	Het
Kcnh5	T	C	12: 75,184,465 (GRCm39)	D86G	probably benign	Het
Kcnt2	G	A	1: 140,282,285 (GRCm39)	S90N	probably benign	Het
Kif14	A	G	1: 136,396,017 (GRCm39)	N108D	probably benign	Het
Kif14	T	C	1: 136,453,521 (GRCm39)	V1433A	probably benign	Het
Kif14	T	C	1: 136,443,699 (GRCm39)	F1291L	probably benign	Het
Kif14	C	T	1: 136,431,169 (GRCm39)	L1189F	probably benign	Het
Kif14	A	G	1: 136,418,070 (GRCm39)	S868G	probably benign	Het
Kif14	G	A	1: 136,406,103 (GRCm39)	A556T	probably benign	Het
Kif14	A	G	1: 136,396,713 (GRCm39)	K340E	probably damaging	Het
Kif18b	A	G	11: 102,806,367 (GRCm39)		probably null	Het
Kif21b	A	G	1: 136,087,859 (GRCm39)	I983V	possibly damaging	Het
Kpna3	T	A	14: 61,605,150 (GRCm39)	E499V	probably benign	Het
Kremen1	GGG	GGGTGG	11: 5,151,792 (GRCm39)		probably benign	Het
Krt23	A	T	11: 99,383,790 (GRCm39)	V34D	probably damaging	Het
Lad1	C	T	1: 135,755,119 (GRCm39)	P132S	possibly damaging	Het
Lad1	C	T	1: 135,755,761 (GRCm39)	R346C	probably damaging	Het
Lax1	G	A	1: 133,611,372 (GRCm39)	P67S	probably damaging	Het
Lax1	T	C	1: 133,607,716 (GRCm39)	R342G	probably benign	Het
Lax1	T	C	1: 133,608,307 (GRCm39)	N145D	probably benign	Het
Lgr6	C	T	1: 134,931,214 (GRCm39)	S3N	probably benign	Het
Lgr6	G	T	1: 134,918,373 (GRCm39)	H263N	probably benign	Het
Lgr6	A	T	1: 134,915,747 (GRCm39)	S334T	probably benign	Het
Lgr6	C	T	1: 134,914,826 (GRCm39)	V641I	probably benign	Het
Lima1	G	T	15: 99,678,344 (GRCm39)	P539Q	possibly damaging	Het
Lmod1	C	T	1: 135,291,811 (GRCm39)	T222I	probably benign	Het
Megf10	T	C	18: 57,373,864 (GRCm39)		probably null	Het
Mrgbp	T	A	2: 180,227,242 (GRCm39)	N192K	probably damaging	Het
Mrgpra2b	A	G	7: 47,114,627 (GRCm39)	I35T	probably benign	Het
Mroh3	G	C	1: 136,119,882 (GRCm39)	Q440E	possibly damaging	Het
Mrpl3	C	T	9: 104,934,266 (GRCm39)	H130Y	probably benign	Het
Mybph	C	T	1: 134,125,218 (GRCm39)	R249C	probably benign	Het
Mycbp2	A	T	14: 103,392,614 (GRCm39)	C3206S	probably damaging	Het
Nav1	A	T	1: 135,512,465 (GRCm39)	D198E	possibly damaging	Het
Nbeal2	T	A	9: 110,459,925 (GRCm39)	K1844*	probably null	Het
Ndufaf7	A	T	17: 79,245,058 (GRCm39)	K59M	probably damaging	Het
Nr5a2	C	A	1: 136,879,863 (GRCm39)	R35L	probably benign	Het
Obsl1	G	A	1: 75,486,756 (GRCm38)	T1764M	probably benign	Het
Optc	A	T	1: 133,831,534 (GRCm39)		probably null	Het
Optc	C	G	1: 133,832,908 (GRCm39)	S64T	probably benign	Het
Or2f1	C	A	6: 42,721,069 (GRCm39)	L33M	possibly damaging	Het
Or8b12i	A	T	9: 20,082,209 (GRCm39)	Y219*	probably null	Het
Otoa	T	C	7: 120,724,662 (GRCm39)	V447A	probably benign	Het
Papss1	A	G	3: 131,311,728 (GRCm39)	N319D	probably benign	Het
Pcdhb3	G	A	18: 37,434,931 (GRCm39)	G299D	probably damaging	Het
Pcsk4	T	C	10: 80,159,404 (GRCm39)	D432G	probably damaging	Het
Pde4b	T	C	4: 102,462,457 (GRCm39)	I711T	probably benign	Het
Pde5a	G	T	3: 122,541,889 (GRCm39)	L126F	probably damaging	Het
Pigr	C	T	1: 130,772,259 (GRCm39)	A159V	possibly damaging	Het
Pik3c2b	C	T	1: 132,994,365 (GRCm39)	P110S	probably benign	Het
Pinx1	A	G	14: 64,115,559 (GRCm39)		probably null	Het
Plekha6	C	G	1: 133,215,584 (GRCm39)	T792S	probably benign	Het
Ppfia4	G	A	1: 134,227,059 (GRCm39)	P1159S	probably benign	Het
Prelp	C	T	1: 133,842,869 (GRCm39)	R92K	probably benign	Het
Prrx1	T	A	1: 163,089,536 (GRCm39)	N97I	probably damaging	Het
Ptpn7	A	G	1: 135,062,213 (GRCm39)	Q53R	probably benign	Het
Ptprc	A	G	1: 138,035,561 (GRCm39)	S405P	probably benign	Het
Ptprc	T	G	1: 138,027,414 (GRCm39)	N478T	probably benign	Het
Ptprc	T	C	1: 138,039,992 (GRCm39)	K212E	possibly damaging	Het
Ptprc	A	G	1: 138,035,575 (GRCm39)	V400A	probably benign	Het
Ptprc	C	A	1: 138,035,562 (GRCm39)	E402D	probably benign	Het
Rab29	A	G	1: 131,799,848 (GRCm39)	Q141R	probably benign	Het
Rbsn	A	T	6: 92,167,000 (GRCm39)	L548Q	possibly damaging	Het
Ren1	C	G	1: 133,287,745 (GRCm39)	L360V	probably benign	Het
Ren1	A	T	1: 133,287,721 (GRCm39)	N352Y	probably benign	Het
Ren1	A	T	1: 133,286,817 (GRCm39)	E315D	probably benign	Het
Ren1	A	C	1: 133,284,195 (GRCm39)	K187Q	probably benign	Het
Ren1	C	T	1: 133,281,975 (GRCm39)	T32I	probably benign	Het
Ren1	T	A	1: 133,281,944 (GRCm39)	W22R	probably damaging	Het
Ren1	C	G	1: 133,278,516 (GRCm39)		probably null	Het
Rgs22	T	A	15: 36,087,582 (GRCm39)	K445N	probably damaging	Het
Rint1	T	A	5: 24,014,841 (GRCm39)	D352E	probably benign	Het
Rnpep	C	T	1: 135,190,834 (GRCm39)	A571T	possibly damaging	Het
Ro60	T	C	1: 143,635,772 (GRCm39)	D458G	probably benign	Het
Ro60	C	T	1: 143,635,752 (GRCm39)	V465I	probably benign	Het
Septin4	A	T	11: 87,474,262 (GRCm39)	Q60L	probably benign	Het
Sis	A	T	3: 72,872,978 (GRCm39)	C53*	probably null	Het
Slain2	A	G	5: 73,114,957 (GRCm39)	H396R	probably damaging	Het
Slc22a5	G	A	11: 53,757,177 (GRCm39)	P491L	probably damaging	Het
Slc26a9	C	T	1: 131,691,608 (GRCm39)	A617V	probably benign	Het
Slc26a9	C	A	1: 131,693,750 (GRCm39)	R747S	probably benign	Het
Stab2	T	G	10: 86,773,903 (GRCm39)	R809S	probably benign	Het
Tbc1d19	T	G	5: 53,986,714 (GRCm39)	I41S	probably damaging	Het
Thsd7b	G	C	1: 129,605,920 (GRCm39)	A554P	probably benign	Het
Thsd7b	A	C	1: 130,044,368 (GRCm39)	Q1116P	probably benign	Het
Thsd7b	C	T	1: 129,556,628 (GRCm39)	T328I	probably damaging	Het
Thsd7b	T	A	1: 129,595,674 (GRCm39)	F498Y	probably benign	Het
Tnfrsf25	T	A	4: 152,202,761 (GRCm39)		probably null	Het
Tnnt2	C	T	1: 135,773,244 (GRCm39)		probably benign	Het
Traf7	A	G	17: 24,731,353 (GRCm39)	F228L	probably damaging	Het
Trim32	T	A	4: 65,532,634 (GRCm39)	I397N	probably damaging	Het
Tubgcp2	T	C	7: 139,577,968 (GRCm39)	T779A	probably benign	Het
Ube2t	C	T	1: 134,899,905 (GRCm39)	A149V	probably benign	Het
Upf2	A	T	2: 6,032,261 (GRCm39)	S191C	probably damaging	Het
Usp42	T	C	5: 143,700,381 (GRCm39)	D1214G	probably damaging	Het
Vcam1	T	A	3: 115,908,164 (GRCm39)	I633L	probably benign	Het
Vmn2r73	T	C	7: 85,507,086 (GRCm39)	Y742C	probably damaging	Het
Vmn2r81	C	A	10: 79,106,489 (GRCm39)	T489K	probably benign	Het
Ypel1	C	G	16: 16,907,283 (GRCm39)		probably benign	Het
Zc3h11a	C	T	1: 133,552,359 (GRCm39)	V583I	probably benign	Het
Zc3h11a	G	A	1: 133,549,892 (GRCm39)	P695S	probably benign	Het
Zfp169	C	T	13: 48,643,295 (GRCm39)	A611T	possibly damaging	Het
Zfp281	GCGGCAGCTCCGGCAGC	GCGGCAGCTCCGGCAGCTCCGGCAGC	1: 136,553,091 (GRCm39)		probably benign	Het
Zp3r	A	G	1: 130,524,551 (GRCm39)	L164P	probably benign	Het
Zp3r	C	A	1: 130,547,151 (GRCm39)	E8D	possibly damaging	Het

Other mutations in Tbc1d31

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL01433:Tbc1d31	APN	15	57,804,164 (GRCm39)	missense	probably benign	0.03
IGL01955:Tbc1d31	APN	15	57,805,766 (GRCm39)	missense	probably benign	0.24
IGL02024:Tbc1d31	APN	15	57,783,338 (GRCm39)	missense	probably benign	0.10
IGL02501:Tbc1d31	APN	15	57,801,344 (GRCm39)	missense	probably benign	0.11
IGL03133:Tbc1d31	APN	15	57,805,855 (GRCm39)	splice site	probably benign
IGL03159:Tbc1d31	APN	15	57,783,444 (GRCm39)	critical splice donor site	probably null
new_age	UTSW	15	57,815,102 (GRCm39)	missense	probably damaging	1.00
PIT4354001:Tbc1d31	UTSW	15	57,831,329 (GRCm39)	missense	probably benign	0.09
R0239:Tbc1d31	UTSW	15	57,804,149 (GRCm39)	missense	probably benign	0.14
R0239:Tbc1d31	UTSW	15	57,804,149 (GRCm39)	missense	probably benign	0.14
R0375:Tbc1d31	UTSW	15	57,818,746 (GRCm39)	missense	probably benign
R0478:Tbc1d31	UTSW	15	57,795,932 (GRCm39)	missense	probably damaging	1.00
R0576:Tbc1d31	UTSW	15	57,833,120 (GRCm39)	missense	possibly damaging	0.79
R1328:Tbc1d31	UTSW	15	57,805,859 (GRCm39)	splice site	probably benign
R1454:Tbc1d31	UTSW	15	57,815,034 (GRCm39)	nonsense	probably null
R1874:Tbc1d31	UTSW	15	57,779,506 (GRCm39)	missense	probably benign	0.41
R1920:Tbc1d31	UTSW	15	57,775,760 (GRCm39)	missense	probably damaging	1.00
R2111:Tbc1d31	UTSW	15	57,796,040 (GRCm39)	missense	probably benign	0.05
R2174:Tbc1d31	UTSW	15	57,815,137 (GRCm39)	missense	possibly damaging	0.95
R2205:Tbc1d31	UTSW	15	57,816,916 (GRCm39)	missense	probably benign	0.11
R3683:Tbc1d31	UTSW	15	57,815,210 (GRCm39)	critical splice donor site	probably null
R3825:Tbc1d31	UTSW	15	57,779,474 (GRCm39)	missense	probably benign	0.43
R4407:Tbc1d31	UTSW	15	57,783,438 (GRCm39)	missense	possibly damaging	0.93
R4627:Tbc1d31	UTSW	15	57,831,308 (GRCm39)	missense	probably benign
R4792:Tbc1d31	UTSW	15	57,804,124 (GRCm39)	missense	probably benign	0.03
R4804:Tbc1d31	UTSW	15	57,814,502 (GRCm39)	nonsense	probably null
R4909:Tbc1d31	UTSW	15	57,825,661 (GRCm39)	critical splice donor site	probably null
R5077:Tbc1d31	UTSW	15	57,818,797 (GRCm39)	missense	probably benign	0.00
R5230:Tbc1d31	UTSW	15	57,824,315 (GRCm39)	missense	probably damaging	0.99
R5436:Tbc1d31	UTSW	15	57,816,267 (GRCm39)	missense	probably benign	0.04
R5652:Tbc1d31	UTSW	15	57,815,062 (GRCm39)	missense	probably damaging	1.00
R5920:Tbc1d31	UTSW	15	57,805,954 (GRCm39)	missense	probably benign	0.10
R6102:Tbc1d31	UTSW	15	57,799,489 (GRCm39)	missense	probably damaging	1.00
R6176:Tbc1d31	UTSW	15	57,816,192 (GRCm39)	missense	probably damaging	0.99
R6513:Tbc1d31	UTSW	15	57,818,778 (GRCm39)	missense	probably damaging	1.00
R6778:Tbc1d31	UTSW	15	57,801,425 (GRCm39)	missense	probably damaging	1.00
R6795:Tbc1d31	UTSW	15	57,815,102 (GRCm39)	missense	probably damaging	1.00
R7187:Tbc1d31	UTSW	15	57,801,459 (GRCm39)	missense	possibly damaging	0.95
R7308:Tbc1d31	UTSW	15	57,816,212 (GRCm39)	missense	probably damaging	1.00
R7359:Tbc1d31	UTSW	15	57,779,504 (GRCm39)	missense	probably benign	0.00
R7453:Tbc1d31	UTSW	15	57,814,391 (GRCm39)	missense	probably damaging	1.00
R7552:Tbc1d31	UTSW	15	57,804,136 (GRCm39)	missense	probably benign
R7606:Tbc1d31	UTSW	15	57,815,066 (GRCm39)	missense	probably damaging	1.00
R7739:Tbc1d31	UTSW	15	57,799,494 (GRCm39)	nonsense	probably null
R7782:Tbc1d31	UTSW	15	57,821,764 (GRCm39)	missense	possibly damaging	0.89
R8165:Tbc1d31	UTSW	15	57,824,345 (GRCm39)	missense	possibly damaging	0.74
R9187:Tbc1d31	UTSW	15	57,779,485 (GRCm39)	missense	probably damaging	1.00
R9558:Tbc1d31	UTSW	15	57,795,988 (GRCm39)	missense	probably damaging	0.99
R9796:Tbc1d31	UTSW	15	57,833,179 (GRCm39)	missense	probably damaging	0.98

Predicted Primers

PCR Primer
(F):5'- ACGTGCTAACAAGACCTGCCTCTG -3'
(R):5'- ACTCTATTGCTAAACGCTGTCCGC -3'

Sequencing Primer
(F):5'- AATGGGGGAGCTACTCTGC -3'
(R):5'- aacgctgtccgcagctc -3'

Posted On

2014-05-23