Incidental Mutation 'R1772:Kdm3b'
| ID |
196755 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kdm3b
|
| Ensembl Gene |
ENSMUSG00000038773 |
| Gene Name |
KDM3B lysine (K)-specific demethylase 3B |
| Synonyms |
Jmjd1b, 5830462I21Rik, JHDM2B |
| MMRRC Submission |
039803-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.943)
|
| Stock # |
R1772 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
34910100-34971713 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 34936557 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Leucine
at position 280
(I280L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153295
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000043775]
[ENSMUST00000224715]
[ENSMUST00000225195]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000043775
AA Change: I280L
PolyPhen 2
Score 0.001 (Sensitivity: 0.99; Specificity: 0.15)
|
| SMART Domains |
Protein: ENSMUSP00000037628
Gene: ENSMUSG00000038773
AA Change: I280L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
20 |
36 |
N/A |
INTRINSIC |
|
Blast:JmjC
|
149 |
944 |
N/A |
BLAST |
|
Blast:JmjC
|
946 |
1064 |
5e-40 |
BLAST |
|
Blast:JmjC
|
1069 |
1471 |
N/A |
BLAST |
|
JmjC
|
1499 |
1722 |
2.43e-65 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000180512
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000224715
AA Change: I280L
PolyPhen 2
Score 0.015 (Sensitivity: 0.96; Specificity: 0.79)
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000225047
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000225195
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000225260
|
| Meta Mutation Damage Score |
0.0573 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.5%
|
| Validation Efficiency |
97% (107/110) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adgb |
G |
T |
10: 10,258,465 (GRCm39) |
|
probably benign |
Het |
| Aldh1a7 |
T |
C |
19: 20,693,383 (GRCm39) |
K179E |
probably damaging |
Het |
| Angptl7 |
G |
A |
4: 148,581,883 (GRCm39) |
R168C |
probably damaging |
Het |
| Atp8b1 |
T |
A |
18: 64,706,563 (GRCm39) |
I208F |
possibly damaging |
Het |
| Bco1 |
A |
G |
8: 117,857,347 (GRCm39) |
Y438C |
probably benign |
Het |
| Bltp1 |
T |
C |
3: 37,013,581 (GRCm39) |
S1937P |
probably damaging |
Het |
| Btrc |
A |
C |
19: 45,501,100 (GRCm39) |
K218Q |
probably damaging |
Het |
| Cct8l1 |
G |
A |
5: 25,722,697 (GRCm39) |
V471M |
probably damaging |
Het |
| Cd180 |
C |
T |
13: 102,842,750 (GRCm39) |
L599F |
probably benign |
Het |
| Cd300e |
T |
C |
11: 114,945,344 (GRCm39) |
N150S |
probably benign |
Het |
| Clcn1 |
C |
A |
6: 42,271,079 (GRCm39) |
T281K |
probably damaging |
Het |
| Cnnm3 |
T |
C |
1: 36,558,038 (GRCm39) |
S417P |
probably damaging |
Het |
| Cspg4 |
T |
A |
9: 56,804,776 (GRCm39) |
S1862R |
probably benign |
Het |
| Cspg5 |
A |
T |
9: 110,091,206 (GRCm39) |
N432Y |
probably damaging |
Het |
| Cyp2r1 |
T |
A |
7: 114,152,451 (GRCm39) |
I169F |
probably damaging |
Het |
| D130043K22Rik |
T |
A |
13: 25,059,982 (GRCm39) |
S618T |
probably damaging |
Het |
| Diaph3 |
G |
A |
14: 87,202,985 (GRCm39) |
P635L |
probably damaging |
Het |
| Dlg1 |
A |
G |
16: 31,484,485 (GRCm39) |
I38V |
possibly damaging |
Het |
| Dlk1 |
T |
G |
12: 109,425,685 (GRCm39) |
V186G |
probably damaging |
Het |
| Dmxl2 |
T |
C |
9: 54,330,508 (GRCm39) |
|
probably benign |
Het |
| Dnajc17 |
G |
A |
2: 119,014,164 (GRCm39) |
R132* |
probably null |
Het |
| Dock9 |
G |
T |
14: 121,847,210 (GRCm39) |
N1042K |
probably benign |
Het |
| Dok7 |
A |
T |
5: 35,243,994 (GRCm39) |
Q511L |
probably damaging |
Het |
| Espnl |
G |
A |
1: 91,272,325 (GRCm39) |
E562K |
possibly damaging |
Het |
| Evi5 |
G |
A |
5: 107,943,707 (GRCm39) |
T562I |
probably benign |
Het |
| Exd2 |
T |
A |
12: 80,536,253 (GRCm39) |
D294E |
probably benign |
Het |
| Fbn1 |
A |
T |
2: 125,245,148 (GRCm39) |
D246E |
possibly damaging |
Het |
| Fbxw16 |
A |
T |
9: 109,268,650 (GRCm39) |
W247R |
possibly damaging |
Het |
| Fcer1a |
A |
G |
1: 173,053,004 (GRCm39) |
I64T |
probably benign |
Het |
| Fcgbp |
C |
A |
7: 27,804,600 (GRCm39) |
Q1903K |
possibly damaging |
Het |
| Fmn1 |
A |
G |
2: 113,195,700 (GRCm39) |
S467G |
unknown |
Het |
| Fndc7 |
T |
A |
3: 108,777,850 (GRCm39) |
T369S |
probably damaging |
Het |
| Fnta |
T |
C |
8: 26,490,994 (GRCm39) |
|
probably benign |
Het |
| Gak |
A |
T |
5: 108,754,758 (GRCm39) |
H289Q |
probably damaging |
Het |
| Gas2l3 |
A |
G |
10: 89,252,876 (GRCm39) |
|
probably benign |
Het |
| Gbp8 |
T |
C |
5: 105,163,987 (GRCm39) |
N437S |
probably benign |
Het |
| Gk5 |
G |
A |
9: 96,032,850 (GRCm39) |
|
probably null |
Het |
| Hid1 |
A |
T |
11: 115,239,299 (GRCm39) |
V788E |
probably damaging |
Het |
| Hmcn1 |
T |
C |
1: 150,439,319 (GRCm39) |
T5505A |
probably damaging |
Het |
| Igf1r |
T |
A |
7: 67,844,822 (GRCm39) |
M865K |
probably benign |
Het |
| Katnal2 |
G |
A |
18: 77,090,233 (GRCm39) |
T258I |
probably damaging |
Het |
| Kif24 |
A |
G |
4: 41,409,787 (GRCm39) |
V382A |
probably damaging |
Het |
| Kif2a |
A |
T |
13: 107,114,640 (GRCm39) |
|
probably benign |
Het |
| Klhl10 |
A |
G |
11: 100,333,022 (GRCm39) |
I56V |
probably benign |
Het |
| Klk6 |
C |
T |
7: 43,478,695 (GRCm39) |
Q201* |
probably null |
Het |
| Klra3 |
A |
T |
6: 130,300,671 (GRCm39) |
S233T |
probably benign |
Het |
| Krt9 |
A |
T |
11: 100,082,131 (GRCm39) |
M223K |
probably damaging |
Het |
| Lama4 |
G |
A |
10: 38,936,220 (GRCm39) |
E632K |
probably benign |
Het |
| Lamb1 |
T |
C |
12: 31,328,524 (GRCm39) |
Y163H |
probably damaging |
Het |
| Lipo3 |
A |
G |
19: 33,764,821 (GRCm39) |
I11T |
probably benign |
Het |
| Lix1l |
T |
A |
3: 96,531,207 (GRCm39) |
H333Q |
possibly damaging |
Het |
| Mal2 |
T |
A |
15: 54,451,783 (GRCm39) |
M68K |
probably damaging |
Het |
| Map2k2 |
T |
C |
10: 80,956,934 (GRCm39) |
I104T |
probably damaging |
Het |
| Matn2 |
T |
C |
15: 34,428,931 (GRCm39) |
V765A |
probably damaging |
Het |
| Mptx2 |
T |
A |
1: 173,102,040 (GRCm39) |
K216N |
probably damaging |
Het |
| Mup5 |
C |
T |
4: 61,750,578 (GRCm39) |
|
probably null |
Het |
| Mycbp2 |
A |
G |
14: 103,419,855 (GRCm39) |
Y2494H |
probably damaging |
Het |
| Myh3 |
G |
A |
11: 66,990,220 (GRCm39) |
D1622N |
probably benign |
Het |
| Myo6 |
T |
C |
9: 80,177,331 (GRCm39) |
I609T |
possibly damaging |
Het |
| Ndst1 |
G |
A |
18: 60,835,909 (GRCm39) |
T458I |
probably damaging |
Het |
| Neb |
A |
T |
2: 52,125,689 (GRCm39) |
Y3622N |
probably damaging |
Het |
| Ntm |
A |
G |
9: 29,090,396 (GRCm39) |
Y108H |
probably benign |
Het |
| Or13c3 |
T |
G |
4: 52,855,730 (GRCm39) |
K261T |
probably benign |
Het |
| Or1a1b |
T |
C |
11: 74,097,398 (GRCm39) |
I215V |
probably benign |
Het |
| Or52e19 |
T |
C |
7: 102,959,449 (GRCm39) |
Y174H |
possibly damaging |
Het |
| Pappa2 |
T |
A |
1: 158,641,938 (GRCm39) |
I1373F |
possibly damaging |
Het |
| Pear1 |
A |
G |
3: 87,661,799 (GRCm39) |
|
probably benign |
Het |
| Phc3 |
C |
T |
3: 31,015,969 (GRCm39) |
A81T |
probably damaging |
Het |
| Pmepa1 |
A |
G |
2: 173,076,153 (GRCm39) |
S105P |
probably damaging |
Het |
| Ppp6r1 |
T |
C |
7: 4,645,030 (GRCm39) |
I248V |
probably benign |
Het |
| Prdm4 |
G |
A |
10: 85,729,256 (GRCm39) |
T717I |
probably damaging |
Het |
| Prom1 |
T |
C |
5: 44,168,566 (GRCm39) |
T669A |
probably benign |
Het |
| Ptpn5 |
T |
A |
7: 46,740,516 (GRCm39) |
I96F |
probably benign |
Het |
| Ptpro |
T |
C |
6: 137,407,741 (GRCm39) |
L922P |
probably damaging |
Het |
| Reck |
A |
T |
4: 43,890,982 (GRCm39) |
H40L |
probably benign |
Het |
| Rreb1 |
T |
A |
13: 38,114,899 (GRCm39) |
C753S |
probably benign |
Het |
| Sacs |
T |
C |
14: 61,448,346 (GRCm39) |
L3464P |
probably damaging |
Het |
| Samsn1 |
A |
T |
16: 75,667,663 (GRCm39) |
D304E |
probably benign |
Het |
| Scgb2b3 |
T |
C |
7: 31,059,621 (GRCm39) |
N51S |
possibly damaging |
Het |
| Shroom3 |
T |
C |
5: 93,088,515 (GRCm39) |
S341P |
probably damaging |
Het |
| Siglece |
T |
C |
7: 43,308,717 (GRCm39) |
D212G |
probably damaging |
Het |
| Sirpa |
A |
G |
2: 129,458,376 (GRCm39) |
T331A |
probably damaging |
Het |
| Spata21 |
T |
C |
4: 140,838,607 (GRCm39) |
S553P |
possibly damaging |
Het |
| Speer4b |
T |
A |
5: 27,705,236 (GRCm39) |
|
probably benign |
Het |
| Srgap2 |
T |
C |
1: 131,247,376 (GRCm39) |
D552G |
probably damaging |
Het |
| Stab2 |
A |
G |
10: 86,790,098 (GRCm39) |
I556T |
probably benign |
Het |
| Strip1 |
C |
T |
3: 107,534,047 (GRCm39) |
|
probably null |
Het |
| Stxbp6 |
T |
A |
12: 44,949,653 (GRCm39) |
D92V |
probably damaging |
Het |
| Styx |
A |
G |
14: 45,594,215 (GRCm39) |
K46E |
probably damaging |
Het |
| Supt20 |
T |
A |
3: 54,617,841 (GRCm39) |
V314E |
probably damaging |
Het |
| Syne2 |
T |
A |
12: 75,985,503 (GRCm39) |
D1650E |
probably benign |
Het |
| Szt2 |
T |
A |
4: 118,262,714 (GRCm39) |
K21M |
probably damaging |
Het |
| Tbx4 |
A |
T |
11: 85,802,033 (GRCm39) |
H222L |
probably damaging |
Het |
| Tcstv1b |
T |
A |
13: 120,634,725 (GRCm39) |
D2E |
probably benign |
Het |
| Tmx3 |
A |
T |
18: 90,551,121 (GRCm39) |
I254L |
probably benign |
Het |
| Tns2 |
C |
T |
15: 102,017,369 (GRCm39) |
R281C |
probably damaging |
Het |
| Trpv2 |
A |
T |
11: 62,485,052 (GRCm39) |
|
probably benign |
Het |
| Ubap2 |
A |
G |
4: 41,202,380 (GRCm39) |
S683P |
probably benign |
Het |
| Ube2d3 |
C |
T |
3: 135,170,972 (GRCm39) |
R139W |
probably benign |
Het |
| Ubox5 |
G |
T |
2: 130,433,794 (GRCm39) |
Q518K |
probably benign |
Het |
| Usp42 |
T |
C |
5: 143,702,857 (GRCm39) |
N588S |
probably damaging |
Het |
| Vars2 |
G |
A |
17: 35,970,976 (GRCm39) |
T618M |
probably damaging |
Het |
| Wfdc17 |
A |
T |
11: 83,595,730 (GRCm39) |
N65Y |
probably damaging |
Het |
| Zbtb38 |
G |
A |
9: 96,570,094 (GRCm39) |
P330L |
probably damaging |
Het |
| Zfp385a |
C |
T |
15: 103,224,308 (GRCm39) |
|
probably null |
Het |
| Zfp637 |
T |
A |
6: 117,822,373 (GRCm39) |
L167H |
probably damaging |
Het |
|
| Other mutations in Kdm3b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00162:Kdm3b
|
APN |
18 |
34,942,462 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01357:Kdm3b
|
APN |
18 |
34,926,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01615:Kdm3b
|
APN |
18 |
34,962,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01980:Kdm3b
|
APN |
18 |
34,967,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Kdm3b
|
APN |
18 |
34,956,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02346:Kdm3b
|
APN |
18 |
34,967,291 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02417:Kdm3b
|
APN |
18 |
34,941,630 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02531:Kdm3b
|
APN |
18 |
34,928,782 (GRCm39) |
missense |
probably benign |
|
|
IGL02589:Kdm3b
|
APN |
18 |
34,945,471 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL02793:Kdm3b
|
APN |
18 |
34,962,072 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03121:Kdm3b
|
APN |
18 |
34,928,762 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03123:Kdm3b
|
APN |
18 |
34,942,544 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03128:Kdm3b
|
APN |
18 |
34,960,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Affable
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Dotage
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Endearing
|
UTSW |
18 |
34,960,381 (GRCm39) |
splice site |
probably null |
|
|
Oldtimer
|
UTSW |
18 |
34,956,752 (GRCm39) |
nonsense |
probably null |
|
|
PIT4382001:Kdm3b
|
UTSW |
18 |
34,942,140 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4445001:Kdm3b
|
UTSW |
18 |
34,926,168 (GRCm39) |
nonsense |
probably null |
|
|
R0068:Kdm3b
|
UTSW |
18 |
34,957,827 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0068:Kdm3b
|
UTSW |
18 |
34,957,827 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0233:Kdm3b
|
UTSW |
18 |
34,942,473 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0265:Kdm3b
|
UTSW |
18 |
34,928,716 (GRCm39) |
splice site |
probably benign |
|
|
R0306:Kdm3b
|
UTSW |
18 |
34,937,070 (GRCm39) |
missense |
probably benign |
0.35 |
|
R0941:Kdm3b
|
UTSW |
18 |
34,936,605 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0970:Kdm3b
|
UTSW |
18 |
34,942,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1061:Kdm3b
|
UTSW |
18 |
34,929,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1104:Kdm3b
|
UTSW |
18 |
34,952,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1221:Kdm3b
|
UTSW |
18 |
34,941,298 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R1486:Kdm3b
|
UTSW |
18 |
34,967,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1523:Kdm3b
|
UTSW |
18 |
34,926,226 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1558:Kdm3b
|
UTSW |
18 |
34,942,149 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1585:Kdm3b
|
UTSW |
18 |
34,942,345 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1601:Kdm3b
|
UTSW |
18 |
34,941,784 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1650:Kdm3b
|
UTSW |
18 |
34,942,168 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1853:Kdm3b
|
UTSW |
18 |
34,966,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1934:Kdm3b
|
UTSW |
18 |
34,946,597 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1959:Kdm3b
|
UTSW |
18 |
34,945,448 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2079:Kdm3b
|
UTSW |
18 |
34,936,570 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2102:Kdm3b
|
UTSW |
18 |
34,963,200 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2121:Kdm3b
|
UTSW |
18 |
34,929,833 (GRCm39) |
splice site |
probably benign |
|
|
R2281:Kdm3b
|
UTSW |
18 |
34,941,472 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3719:Kdm3b
|
UTSW |
18 |
34,941,724 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3755:Kdm3b
|
UTSW |
18 |
34,941,349 (GRCm39) |
missense |
probably benign |
|
|
R3857:Kdm3b
|
UTSW |
18 |
34,966,440 (GRCm39) |
missense |
probably benign |
|
|
R4165:Kdm3b
|
UTSW |
18 |
34,928,797 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4166:Kdm3b
|
UTSW |
18 |
34,928,797 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4372:Kdm3b
|
UTSW |
18 |
34,960,497 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4672:Kdm3b
|
UTSW |
18 |
34,941,630 (GRCm39) |
missense |
probably benign |
|
|
R4933:Kdm3b
|
UTSW |
18 |
34,943,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4969:Kdm3b
|
UTSW |
18 |
34,955,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5009:Kdm3b
|
UTSW |
18 |
34,957,763 (GRCm39) |
missense |
probably benign |
0.42 |
|
R5059:Kdm3b
|
UTSW |
18 |
34,910,250 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5092:Kdm3b
|
UTSW |
18 |
34,946,515 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5270:Kdm3b
|
UTSW |
18 |
34,960,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5816:Kdm3b
|
UTSW |
18 |
34,961,522 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5970:Kdm3b
|
UTSW |
18 |
34,962,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6244:Kdm3b
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6705:Kdm3b
|
UTSW |
18 |
34,952,926 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6723:Kdm3b
|
UTSW |
18 |
34,926,058 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6909:Kdm3b
|
UTSW |
18 |
34,960,381 (GRCm39) |
splice site |
probably null |
|
|
R6958:Kdm3b
|
UTSW |
18 |
34,941,336 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7026:Kdm3b
|
UTSW |
18 |
34,955,517 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7289:Kdm3b
|
UTSW |
18 |
34,927,557 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7488:Kdm3b
|
UTSW |
18 |
34,957,934 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7587:Kdm3b
|
UTSW |
18 |
34,930,080 (GRCm39) |
splice site |
probably null |
|
|
R7695:Kdm3b
|
UTSW |
18 |
34,927,612 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7846:Kdm3b
|
UTSW |
18 |
34,942,293 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7984:Kdm3b
|
UTSW |
18 |
34,956,752 (GRCm39) |
nonsense |
probably null |
|
|
R7997:Kdm3b
|
UTSW |
18 |
34,941,336 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8035:Kdm3b
|
UTSW |
18 |
34,941,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8064:Kdm3b
|
UTSW |
18 |
34,946,460 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8141:Kdm3b
|
UTSW |
18 |
34,961,599 (GRCm39) |
nonsense |
probably null |
|
|
R8302:Kdm3b
|
UTSW |
18 |
34,967,388 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8328:Kdm3b
|
UTSW |
18 |
34,926,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8443:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8513:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8515:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8523:Kdm3b
|
UTSW |
18 |
34,926,129 (GRCm39) |
missense |
probably benign |
0.04 |
|
R8717:Kdm3b
|
UTSW |
18 |
34,952,840 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8725:Kdm3b
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8727:Kdm3b
|
UTSW |
18 |
34,960,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8762:Kdm3b
|
UTSW |
18 |
34,937,157 (GRCm39) |
missense |
probably benign |
|
|
R8835:Kdm3b
|
UTSW |
18 |
34,941,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8918:Kdm3b
|
UTSW |
18 |
34,970,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9015:Kdm3b
|
UTSW |
18 |
34,963,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9144:Kdm3b
|
UTSW |
18 |
34,927,558 (GRCm39) |
missense |
probably benign |
|
|
R9246:Kdm3b
|
UTSW |
18 |
34,941,480 (GRCm39) |
nonsense |
probably null |
|
|
R9376:Kdm3b
|
UTSW |
18 |
34,970,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
X0028:Kdm3b
|
UTSW |
18 |
34,932,319 (GRCm39) |
splice site |
probably null |
|
|
X0067:Kdm3b
|
UTSW |
18 |
34,956,570 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Kdm3b
|
UTSW |
18 |
34,942,122 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCTTAGAGCAGCATCAGAGCGG -3'
(R):5'- TGTGGCTGAAGCATACGGAGTG -3'
Sequencing Primer
(F):5'- AGCGGTGCCTGCTCTAAATG -3'
(R):5'- GGCTCATCCTGTACCACCAG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation