Incidental Mutation 'R1773:Chl1'
| ID |
196803 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Chl1
|
| Ensembl Gene |
ENSMUSG00000030077 |
| Gene Name |
cell adhesion molecule L1-like |
| Synonyms |
A530023M13Rik, close homolog of L1, LICAM2, CALL |
| MMRRC Submission |
039804-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.458)
|
| Stock # |
R1773 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
103487372-103709999 bp(+) (GRCm39) |
| Type of Mutation |
critical splice donor site (2 bp from exon) |
| DNA Base Change (assembly) |
T to C
at 103624292 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000144725
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000066905]
[ENSMUST00000203830]
[ENSMUST00000203912]
[ENSMUST00000204321]
|
| AlphaFold |
P70232 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000066905
|
| SMART Domains |
Protein: ENSMUSP00000063933
Gene: ENSMUSG00000030077
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
253 |
317 |
3.76e-17 |
SMART |
|
IGc2
|
343 |
408 |
1.61e-7 |
SMART |
|
IGc2
|
436 |
501 |
1.56e-5 |
SMART |
|
IG
|
521 |
609 |
6.02e-7 |
SMART |
|
IG_like
|
539 |
598 |
1.27e-1 |
SMART |
|
FN3
|
612 |
695 |
2.24e-13 |
SMART |
|
FN3
|
712 |
794 |
1.92e-3 |
SMART |
|
FN3
|
810 |
901 |
2.3e-1 |
SMART |
|
FN3
|
916 |
1002 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1082 |
1104 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1105 |
1190 |
3.9e-33 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000203489
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000203830
|
| SMART Domains |
Protein: ENSMUSP00000144758
Gene: ENSMUSG00000030077
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
253 |
317 |
3.76e-17 |
SMART |
|
IGc2
|
343 |
408 |
1.61e-7 |
SMART |
|
IGc2
|
436 |
501 |
1.56e-5 |
SMART |
|
IG
|
521 |
609 |
6.02e-7 |
SMART |
|
IG_like
|
539 |
598 |
1.27e-1 |
SMART |
|
FN3
|
612 |
695 |
2.24e-13 |
SMART |
|
FN3
|
712 |
794 |
1.92e-3 |
SMART |
|
FN3
|
810 |
901 |
2.3e-1 |
SMART |
|
FN3
|
916 |
1002 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1082 |
1104 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1105 |
1190 |
3.9e-33 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000203912
|
| SMART Domains |
Protein: ENSMUSP00000145026
Gene: ENSMUSG00000030077
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
3.14e-2 |
SMART |
|
IG
|
138 |
225 |
1.36e-5 |
SMART |
|
IGc2
|
269 |
333 |
3.76e-17 |
SMART |
|
IGc2
|
359 |
424 |
1.61e-7 |
SMART |
|
IGc2
|
452 |
517 |
1.56e-5 |
SMART |
|
IG
|
537 |
625 |
6.02e-7 |
SMART |
|
IG_like
|
555 |
614 |
1.27e-1 |
SMART |
|
FN3
|
628 |
711 |
2.24e-13 |
SMART |
|
FN3
|
728 |
810 |
1.92e-3 |
SMART |
|
FN3
|
826 |
917 |
2.3e-1 |
SMART |
|
FN3
|
932 |
1018 |
4.09e-7 |
SMART |
|
transmembrane domain
|
1044 |
1066 |
N/A |
INTRINSIC |
|
Pfam:Bravo_FIGEY
|
1067 |
1131 |
2.5e-12 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000204321
|
| SMART Domains |
Protein: ENSMUSP00000144725
Gene: ENSMUSG00000030077
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
25 |
N/A |
INTRINSIC |
|
IG_like
|
48 |
116 |
1.3e-4 |
SMART |
|
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.4%
- 20x: 92.9%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the L1 gene family of neural cell adhesion molecules. It is a neural recognition molecule that may be involved in signal transduction pathways. The deletion of one copy of this gene may be responsible for mental defects in patients with 3p- syndrome. This protein may also play a role in the growth of certain cancers. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Nov 2011]
PHENOTYPE: Homozygous mutation of this gene results in enlargement of the lateral ventricles and altered hippocampal mossy fiber organization. Mutant animals exhibit altered exploratory behavior. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
A |
G |
7: 27,280,020 (GRCm39) |
K334E |
probably damaging |
Het |
| Abca12 |
A |
G |
1: 71,327,755 (GRCm39) |
Y1442H |
probably damaging |
Het |
| Acot12 |
A |
G |
13: 91,905,676 (GRCm39) |
T79A |
probably benign |
Het |
| Adipoq |
A |
C |
16: 22,973,988 (GRCm39) |
Q26P |
unknown |
Het |
| Afg2a |
T |
C |
3: 37,493,334 (GRCm39) |
F515L |
probably damaging |
Het |
| Akap13 |
T |
A |
7: 75,333,199 (GRCm39) |
N1582K |
possibly damaging |
Het |
| Alg9 |
A |
G |
9: 50,690,396 (GRCm39) |
T133A |
probably benign |
Het |
| Anks3 |
T |
C |
16: 4,765,158 (GRCm39) |
T418A |
probably benign |
Het |
| Ano3 |
A |
C |
2: 110,591,800 (GRCm39) |
L37R |
probably damaging |
Het |
| Ano9 |
A |
G |
7: 140,688,291 (GRCm39) |
F178L |
possibly damaging |
Het |
| Arhgef12 |
A |
G |
9: 42,916,838 (GRCm39) |
|
probably null |
Het |
| Arl16 |
T |
A |
11: 120,356,589 (GRCm39) |
I137F |
possibly damaging |
Het |
| Brpf1 |
T |
A |
6: 113,296,892 (GRCm39) |
S959T |
possibly damaging |
Het |
| Ccdc27 |
C |
T |
4: 154,126,222 (GRCm39) |
R89Q |
unknown |
Het |
| Cd109 |
A |
C |
9: 78,611,006 (GRCm39) |
Q1207H |
probably benign |
Het |
| Cd14 |
A |
T |
18: 36,858,357 (GRCm39) |
V366D |
possibly damaging |
Het |
| Cep290 |
G |
A |
10: 100,346,435 (GRCm39) |
V538I |
probably benign |
Het |
| Cep57 |
G |
A |
9: 13,727,364 (GRCm39) |
A202V |
probably damaging |
Het |
| Cmah |
T |
G |
13: 24,601,282 (GRCm39) |
F29L |
probably benign |
Het |
| Cracd |
G |
T |
5: 77,015,052 (GRCm39) |
A42S |
possibly damaging |
Het |
| Crybg1 |
A |
G |
10: 43,868,544 (GRCm39) |
V1378A |
possibly damaging |
Het |
| Cryzl2 |
A |
G |
1: 157,298,292 (GRCm39) |
K227R |
probably benign |
Het |
| D130043K22Rik |
T |
G |
13: 25,066,585 (GRCm39) |
V794G |
possibly damaging |
Het |
| Ddx4 |
T |
A |
13: 112,736,436 (GRCm39) |
T645S |
probably benign |
Het |
| Dhcr7 |
C |
T |
7: 143,401,195 (GRCm39) |
R453C |
possibly damaging |
Het |
| Dhx8 |
T |
C |
11: 101,643,189 (GRCm39) |
Y754H |
possibly damaging |
Het |
| Dip2b |
T |
A |
15: 100,091,842 (GRCm39) |
D860E |
probably benign |
Het |
| Dnah7a |
T |
C |
1: 53,472,046 (GRCm39) |
|
probably null |
Het |
| Dst |
A |
G |
1: 34,330,980 (GRCm39) |
D6937G |
probably damaging |
Het |
| Dusp1 |
A |
G |
17: 26,726,081 (GRCm39) |
I204T |
probably damaging |
Het |
| Dync2h1 |
T |
A |
9: 7,128,256 (GRCm39) |
Q1859L |
probably damaging |
Het |
| E4f1 |
C |
A |
17: 24,665,558 (GRCm39) |
G328V |
probably damaging |
Het |
| Eml5 |
T |
C |
12: 98,765,098 (GRCm39) |
Y1617C |
probably damaging |
Het |
| Espn |
G |
T |
4: 152,212,686 (GRCm39) |
P622Q |
probably damaging |
Het |
| Fam184b |
G |
A |
5: 45,741,676 (GRCm39) |
P185L |
possibly damaging |
Het |
| Fn1 |
T |
A |
1: 71,676,542 (GRCm39) |
D563V |
probably damaging |
Het |
| Gad2 |
A |
G |
2: 22,580,219 (GRCm39) |
Y540C |
probably benign |
Het |
| Garin1b |
T |
C |
6: 29,334,152 (GRCm39) |
S335P |
possibly damaging |
Het |
| Gdf11 |
T |
C |
10: 128,727,163 (GRCm39) |
D131G |
probably damaging |
Het |
| Gm19965 |
T |
A |
1: 116,748,989 (GRCm39) |
Y223* |
probably null |
Het |
| H2-M10.6 |
A |
G |
17: 37,123,076 (GRCm39) |
K3R |
probably benign |
Het |
| Hid1 |
A |
G |
11: 115,239,336 (GRCm39) |
Y776H |
probably damaging |
Het |
| Hivep3 |
A |
T |
4: 119,956,034 (GRCm39) |
K1450I |
probably damaging |
Het |
| Icam5 |
T |
C |
9: 20,944,821 (GRCm39) |
L128P |
possibly damaging |
Het |
| Idnk |
T |
C |
13: 58,305,526 (GRCm39) |
V9A |
probably damaging |
Het |
| Il4ra |
A |
T |
7: 125,166,354 (GRCm39) |
T33S |
possibly damaging |
Het |
| Ino80 |
A |
G |
2: 119,248,890 (GRCm39) |
V990A |
probably benign |
Het |
| Krtap4-9 |
T |
C |
11: 99,676,396 (GRCm39) |
|
probably benign |
Het |
| Lrrk2 |
A |
G |
15: 91,664,184 (GRCm39) |
I1974V |
possibly damaging |
Het |
| Mcm3ap |
C |
T |
10: 76,306,994 (GRCm39) |
A369V |
probably benign |
Het |
| Nek6 |
A |
G |
2: 38,472,431 (GRCm39) |
M252V |
probably benign |
Het |
| Nfasc |
T |
A |
1: 132,538,577 (GRCm39) |
I443F |
probably damaging |
Het |
| Nme8 |
T |
G |
13: 19,881,206 (GRCm39) |
M1L |
probably damaging |
Het |
| Npnt |
T |
A |
3: 132,610,454 (GRCm39) |
Q423L |
possibly damaging |
Het |
| Nup133 |
A |
T |
8: 124,657,722 (GRCm39) |
C404* |
probably null |
Het |
| Or2b7 |
T |
C |
13: 21,739,982 (GRCm39) |
D70G |
probably damaging |
Het |
| Or4c124 |
A |
G |
2: 89,156,086 (GRCm39) |
V146A |
probably benign |
Het |
| Or4f14b |
A |
G |
2: 111,775,204 (GRCm39) |
V199A |
possibly damaging |
Het |
| Or56a4 |
T |
C |
7: 104,806,190 (GRCm39) |
E233G |
probably benign |
Het |
| Or5an1c |
T |
C |
19: 12,219,023 (GRCm39) |
M1V |
probably null |
Het |
| Or6c213 |
A |
G |
10: 129,574,312 (GRCm39) |
L158S |
probably damaging |
Het |
| Otog |
T |
A |
7: 45,937,583 (GRCm39) |
I1764N |
probably benign |
Het |
| Oxa1l |
A |
G |
14: 54,600,909 (GRCm39) |
I127M |
probably benign |
Het |
| P4hb |
C |
A |
11: 120,463,552 (GRCm39) |
V28F |
probably damaging |
Het |
| Pbld2 |
C |
T |
10: 62,890,150 (GRCm39) |
A186V |
probably benign |
Het |
| Pdzph1 |
G |
T |
17: 59,281,808 (GRCm39) |
T158K |
probably damaging |
Het |
| Pgm2 |
T |
A |
5: 64,265,194 (GRCm39) |
|
probably null |
Het |
| Phip |
A |
T |
9: 82,758,242 (GRCm39) |
S1484T |
probably benign |
Het |
| Pikfyve |
T |
C |
1: 65,231,430 (GRCm39) |
L100P |
probably damaging |
Het |
| Pikfyve |
T |
C |
1: 65,285,529 (GRCm39) |
S923P |
probably benign |
Het |
| Pla2g4e |
A |
G |
2: 120,075,202 (GRCm39) |
S63P |
probably benign |
Het |
| Plekhh2 |
A |
G |
17: 84,906,693 (GRCm39) |
E1176G |
probably damaging |
Het |
| Prlr |
T |
A |
15: 10,325,404 (GRCm39) |
Y192* |
probably null |
Het |
| Pten |
T |
A |
19: 32,775,472 (GRCm39) |
C71S |
probably damaging |
Het |
| Rbbp8nl |
A |
G |
2: 179,922,987 (GRCm39) |
L202P |
probably benign |
Het |
| Ripor2 |
T |
A |
13: 24,885,237 (GRCm39) |
S491T |
probably benign |
Het |
| Robo1 |
A |
T |
16: 72,801,399 (GRCm39) |
I1008F |
probably benign |
Het |
| Scg2 |
T |
C |
1: 79,413,352 (GRCm39) |
N417S |
probably benign |
Het |
| Scn8a |
A |
G |
15: 100,937,496 (GRCm39) |
I1581V |
probably damaging |
Het |
| Slc22a8 |
T |
A |
19: 8,571,593 (GRCm39) |
I108N |
probably damaging |
Het |
| Slc9a8 |
A |
T |
2: 167,313,385 (GRCm39) |
T416S |
possibly damaging |
Het |
| Spata32 |
T |
A |
11: 103,099,644 (GRCm39) |
E287V |
probably damaging |
Het |
| Tgfbrap1 |
C |
T |
1: 43,114,512 (GRCm39) |
G196D |
probably damaging |
Het |
| Tgm5 |
G |
T |
2: 120,908,131 (GRCm39) |
T15K |
possibly damaging |
Het |
| Tmc1 |
C |
T |
19: 20,803,865 (GRCm39) |
|
probably null |
Het |
| Tmem177 |
T |
C |
1: 119,838,306 (GRCm39) |
I124M |
possibly damaging |
Het |
| Trim30a |
A |
G |
7: 104,085,108 (GRCm39) |
F34S |
probably damaging |
Het |
| Tsn |
T |
C |
1: 118,232,969 (GRCm39) |
T112A |
probably benign |
Het |
| Tspyl5 |
T |
G |
15: 33,686,922 (GRCm39) |
N341T |
probably benign |
Het |
| Vmn2r108 |
C |
T |
17: 20,689,335 (GRCm39) |
C540Y |
probably damaging |
Het |
| Vrtn |
C |
T |
12: 84,696,998 (GRCm39) |
R583W |
probably damaging |
Het |
| Wnt1 |
T |
C |
15: 98,689,638 (GRCm39) |
S142P |
probably damaging |
Het |
| Wrn |
A |
T |
8: 33,833,589 (GRCm39) |
I108N |
probably damaging |
Het |
| Zfhx2 |
A |
C |
14: 55,310,348 (GRCm39) |
C733G |
possibly damaging |
Het |
| Zfp219 |
T |
C |
14: 52,244,563 (GRCm39) |
T539A |
probably damaging |
Het |
| Zswim8 |
T |
A |
14: 20,761,598 (GRCm39) |
M177K |
probably damaging |
Het |
|
| Other mutations in Chl1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00590:Chl1
|
APN |
6 |
103,670,022 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL00786:Chl1
|
APN |
6 |
103,652,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00959:Chl1
|
APN |
6 |
103,686,211 (GRCm39) |
splice site |
probably null |
|
|
IGL01109:Chl1
|
APN |
6 |
103,692,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01354:Chl1
|
APN |
6 |
103,642,814 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01367:Chl1
|
APN |
6 |
103,706,186 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL01371:Chl1
|
APN |
6 |
103,692,325 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01599:Chl1
|
APN |
6 |
103,685,445 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL01724:Chl1
|
APN |
6 |
103,626,534 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02001:Chl1
|
APN |
6 |
103,619,017 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL02066:Chl1
|
APN |
6 |
103,675,185 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02122:Chl1
|
APN |
6 |
103,652,098 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02340:Chl1
|
APN |
6 |
103,675,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02420:Chl1
|
APN |
6 |
103,692,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02421:Chl1
|
APN |
6 |
103,694,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02429:Chl1
|
APN |
6 |
103,641,770 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02825:Chl1
|
APN |
6 |
103,645,764 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02858:Chl1
|
APN |
6 |
103,618,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03169:Chl1
|
APN |
6 |
103,642,928 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03185:Chl1
|
APN |
6 |
103,642,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03189:Chl1
|
APN |
6 |
103,660,168 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL03288:Chl1
|
APN |
6 |
103,652,058 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03404:Chl1
|
APN |
6 |
103,670,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03052:Chl1
|
UTSW |
6 |
103,668,628 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0060:Chl1
|
UTSW |
6 |
103,688,019 (GRCm39) |
splice site |
probably benign |
|
|
R0060:Chl1
|
UTSW |
6 |
103,688,019 (GRCm39) |
splice site |
probably benign |
|
|
R0062:Chl1
|
UTSW |
6 |
103,726,613 (GRCm39) |
missense |
unknown |
|
|
R0314:Chl1
|
UTSW |
6 |
103,624,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0322:Chl1
|
UTSW |
6 |
103,678,844 (GRCm39) |
splice site |
probably benign |
|
|
R0685:Chl1
|
UTSW |
6 |
103,685,503 (GRCm39) |
splice site |
probably null |
|
|
R0702:Chl1
|
UTSW |
6 |
103,683,583 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1056:Chl1
|
UTSW |
6 |
103,652,038 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1138:Chl1
|
UTSW |
6 |
103,670,140 (GRCm39) |
missense |
probably benign |
0.05 |
|
R1483:Chl1
|
UTSW |
6 |
103,624,248 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1571:Chl1
|
UTSW |
6 |
103,685,445 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1620:Chl1
|
UTSW |
6 |
103,667,203 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1645:Chl1
|
UTSW |
6 |
103,660,141 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1852:Chl1
|
UTSW |
6 |
103,676,120 (GRCm39) |
splice site |
probably null |
|
|
R1891:Chl1
|
UTSW |
6 |
103,691,544 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2146:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2147:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2148:Chl1
|
UTSW |
6 |
103,692,362 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2163:Chl1
|
UTSW |
6 |
103,688,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2291:Chl1
|
UTSW |
6 |
103,692,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2920:Chl1
|
UTSW |
6 |
103,672,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Chl1
|
UTSW |
6 |
103,675,116 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3979:Chl1
|
UTSW |
6 |
103,692,245 (GRCm39) |
nonsense |
probably null |
|
|
R4987:Chl1
|
UTSW |
6 |
103,651,938 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5266:Chl1
|
UTSW |
6 |
103,677,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5478:Chl1
|
UTSW |
6 |
103,660,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5523:Chl1
|
UTSW |
6 |
103,685,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5887:Chl1
|
UTSW |
6 |
103,694,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5986:Chl1
|
UTSW |
6 |
103,686,152 (GRCm39) |
missense |
probably benign |
0.45 |
|
R6101:Chl1
|
UTSW |
6 |
103,669,993 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6179:Chl1
|
UTSW |
6 |
103,660,204 (GRCm39) |
missense |
probably benign |
0.38 |
|
R6366:Chl1
|
UTSW |
6 |
103,706,197 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6634:Chl1
|
UTSW |
6 |
103,667,220 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6824:Chl1
|
UTSW |
6 |
103,691,510 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6913:Chl1
|
UTSW |
6 |
103,642,909 (GRCm39) |
nonsense |
probably null |
|
|
R7097:Chl1
|
UTSW |
6 |
103,683,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7122:Chl1
|
UTSW |
6 |
103,683,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7198:Chl1
|
UTSW |
6 |
103,683,517 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7203:Chl1
|
UTSW |
6 |
103,668,635 (GRCm39) |
missense |
probably benign |
0.13 |
|
R7527:Chl1
|
UTSW |
6 |
103,688,162 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7625:Chl1
|
UTSW |
6 |
103,706,086 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7667:Chl1
|
UTSW |
6 |
103,672,456 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R7683:Chl1
|
UTSW |
6 |
103,668,613 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R7712:Chl1
|
UTSW |
6 |
103,688,063 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7838:Chl1
|
UTSW |
6 |
103,668,635 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7863:Chl1
|
UTSW |
6 |
103,683,475 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7874:Chl1
|
UTSW |
6 |
103,667,224 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7998:Chl1
|
UTSW |
6 |
103,706,250 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8044:Chl1
|
UTSW |
6 |
103,683,593 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8059:Chl1
|
UTSW |
6 |
103,651,948 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8462:Chl1
|
UTSW |
6 |
103,706,130 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8558:Chl1
|
UTSW |
6 |
103,685,390 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8827:Chl1
|
UTSW |
6 |
103,670,111 (GRCm39) |
missense |
probably benign |
|
|
R8865:Chl1
|
UTSW |
6 |
103,685,822 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8939:Chl1
|
UTSW |
6 |
103,642,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9092:Chl1
|
UTSW |
6 |
103,645,815 (GRCm39) |
unclassified |
probably benign |
|
|
Z1177:Chl1
|
UTSW |
6 |
103,674,910 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Chl1
|
UTSW |
6 |
103,670,057 (GRCm39) |
nonsense |
probably null |
|
|
Z1191:Chl1
|
UTSW |
6 |
103,660,172 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- gacactgaacataaactatcacaCTTACCGA -3'
(R):5'- cacacacacacacTCAAGCAAACTC -3'
Sequencing Primer
(F):5'- ctatcacaCTTACCGATGTAGAATAC -3'
(R):5'- AAAGAAGTACACAGTTAAGTTCTACC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation