Incidental Mutation 'R1777:Pzp'
| ID |
197107 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pzp
|
| Ensembl Gene |
ENSMUSG00000030359 |
| Gene Name |
PZP, alpha-2-macroglobulin like |
| Synonyms |
|
| MMRRC Submission |
039808-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.122)
|
| Stock # |
R1777 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
6 |
| Chromosomal Location |
128460530-128503683 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 128467535 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1089
(E1089G)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112132]
|
| AlphaFold |
Q61838 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000032510
AA Change: E1089G
PolyPhen 2
Score 0.854 (Sensitivity: 0.83; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000032510
Gene: ENSMUSG00000030359
AA Change: E1089G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
18 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
126 |
219 |
8.8e-22 |
PFAM |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
A2M_N_2
|
458 |
606 |
6.18e-40 |
SMART |
|
A2M
|
750 |
840 |
2.27e-38 |
SMART |
|
Pfam:Thiol-ester_cl
|
973 |
1002 |
5.7e-19 |
PFAM |
|
Pfam:A2M_comp
|
1022 |
1284 |
1.6e-93 |
PFAM |
|
A2M_recep
|
1395 |
1482 |
6.47e-43 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000112132
AA Change: E1089G
PolyPhen 2
Score 0.672 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000107760
Gene: ENSMUSG00000030359
AA Change: E1089G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
18 |
N/A |
INTRINSIC |
|
Pfam:A2M_N
|
126 |
219 |
3.2e-23 |
PFAM |
|
low complexity region
|
327 |
338 |
N/A |
INTRINSIC |
|
A2M_N_2
|
458 |
606 |
6.18e-40 |
SMART |
|
A2M
|
750 |
840 |
2.27e-38 |
SMART |
|
Pfam:Thiol-ester_cl
|
973 |
1003 |
4e-19 |
PFAM |
|
Pfam:A2M_comp
|
1022 |
1284 |
2.1e-90 |
PFAM |
|
A2M_recep
|
1395 |
1482 |
6.47e-43 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000203753
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204037
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204081
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000204291
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Homozygotes mutant null mice show higher bone mineral density, hypoactivity, and decreased heart rate. Mice homozygous for a different null allele show resistance to the lethal effects of endotoxin, increased susceptibility to diet-induced acute pancreatitis, and altered LPS-induced febrile and cytokine responses. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930444P10Rik |
T |
A |
1: 16,148,813 (GRCm39) |
D111V |
possibly damaging |
Het |
| Ap2a1 |
G |
A |
7: 44,553,576 (GRCm39) |
T597M |
probably damaging |
Het |
| Arhgap25 |
A |
G |
6: 87,440,289 (GRCm39) |
S364P |
probably benign |
Het |
| Atp6v1a |
G |
T |
16: 43,935,068 (GRCm39) |
Y40* |
probably null |
Het |
| Cdh1 |
T |
A |
8: 107,383,467 (GRCm39) |
H235Q |
probably damaging |
Het |
| Cntln |
A |
G |
4: 85,048,916 (GRCm39) |
E1376G |
probably benign |
Het |
| Cntnap5b |
T |
A |
1: 100,297,803 (GRCm39) |
S781T |
probably benign |
Het |
| Cpne4 |
A |
G |
9: 104,749,887 (GRCm39) |
T64A |
probably damaging |
Het |
| Ctsg |
T |
C |
14: 56,338,058 (GRCm39) |
Y179C |
probably damaging |
Het |
| Cx3cr1 |
A |
G |
9: 119,880,659 (GRCm39) |
Y248H |
probably damaging |
Het |
| Dhx37 |
T |
C |
5: 125,506,995 (GRCm39) |
E167G |
probably benign |
Het |
| Dnajc21 |
C |
A |
15: 10,449,693 (GRCm39) |
A443S |
probably benign |
Het |
| Drd5 |
T |
C |
5: 38,477,504 (GRCm39) |
S166P |
probably damaging |
Het |
| Dscaml1 |
T |
C |
9: 45,595,054 (GRCm39) |
L719P |
possibly damaging |
Het |
| Eif2ak4 |
T |
C |
2: 118,261,320 (GRCm39) |
I542T |
probably damaging |
Het |
| Ephb3 |
G |
A |
16: 21,035,985 (GRCm39) |
G291E |
probably damaging |
Het |
| Eva1a |
T |
A |
6: 82,069,137 (GRCm39) |
Y155N |
probably damaging |
Het |
| Exog |
C |
T |
9: 119,278,884 (GRCm39) |
P189L |
probably damaging |
Het |
| Fam13b |
A |
G |
18: 34,590,813 (GRCm39) |
V455A |
possibly damaging |
Het |
| Fmn2 |
C |
A |
1: 174,409,488 (GRCm39) |
Q574K |
unknown |
Het |
| Gm6871 |
A |
T |
7: 41,195,143 (GRCm39) |
S531R |
probably benign |
Het |
| Golga2 |
T |
A |
2: 32,195,482 (GRCm39) |
|
probably null |
Het |
| Hydin |
C |
T |
8: 111,316,203 (GRCm39) |
P4365L |
probably benign |
Het |
| Ints8 |
A |
T |
4: 11,225,600 (GRCm39) |
|
probably null |
Het |
| Kbtbd12 |
A |
C |
6: 88,595,042 (GRCm39) |
S263A |
probably benign |
Het |
| Kcng4 |
T |
C |
8: 120,360,226 (GRCm39) |
D50G |
probably benign |
Het |
| Klhl18 |
A |
T |
9: 110,266,469 (GRCm39) |
C217S |
probably benign |
Het |
| Klk1b4 |
A |
G |
7: 43,856,875 (GRCm39) |
|
probably benign |
Het |
| Klk7 |
G |
A |
7: 43,462,753 (GRCm39) |
C186Y |
probably damaging |
Het |
| Krbox5 |
A |
T |
13: 67,981,984 (GRCm39) |
R65S |
probably benign |
Het |
| Krit1 |
T |
C |
5: 3,886,799 (GRCm39) |
Y635H |
probably damaging |
Het |
| Lipo4 |
A |
T |
19: 33,476,721 (GRCm39) |
D342E |
probably damaging |
Het |
| Lsm14b |
T |
G |
2: 179,673,588 (GRCm39) |
D199E |
probably benign |
Het |
| Map3k4 |
A |
T |
17: 12,490,617 (GRCm39) |
N271K |
possibly damaging |
Het |
| Mast1 |
T |
A |
8: 85,638,697 (GRCm39) |
N1544I |
probably benign |
Het |
| Megf6 |
T |
A |
4: 154,355,147 (GRCm39) |
C1487* |
probably null |
Het |
| Mlh3 |
C |
A |
12: 85,315,528 (GRCm39) |
K219N |
possibly damaging |
Het |
| Mtmr4 |
A |
G |
11: 87,493,656 (GRCm39) |
K305E |
probably damaging |
Het |
| Myo15a |
A |
G |
11: 60,405,762 (GRCm39) |
M3105V |
probably benign |
Het |
| Nbas |
A |
T |
12: 13,563,563 (GRCm39) |
I1958F |
probably benign |
Het |
| Nepro |
A |
T |
16: 44,556,216 (GRCm39) |
Q458L |
probably damaging |
Het |
| Opa3 |
T |
C |
7: 18,978,837 (GRCm39) |
Y101H |
probably damaging |
Het |
| Or11g25 |
T |
A |
14: 50,723,757 (GRCm39) |
F281I |
probably benign |
Het |
| Or14c41 |
T |
A |
7: 86,235,272 (GRCm39) |
I263N |
probably benign |
Het |
| Or4f15 |
T |
A |
2: 111,814,042 (GRCm39) |
I126L |
possibly damaging |
Het |
| Or51f1d |
T |
C |
7: 102,700,583 (GRCm39) |
I26T |
probably benign |
Het |
| Or5ac16 |
A |
G |
16: 59,022,379 (GRCm39) |
S137P |
probably benign |
Het |
| Or8b12 |
A |
G |
9: 37,657,607 (GRCm39) |
Y59C |
possibly damaging |
Het |
| Pate3 |
T |
C |
9: 35,559,412 (GRCm39) |
N2D |
probably benign |
Het |
| Pcdhb21 |
T |
A |
18: 37,648,771 (GRCm39) |
D633E |
possibly damaging |
Het |
| Pgm2 |
C |
T |
5: 64,285,125 (GRCm39) |
P589L |
probably benign |
Het |
| Pigg |
T |
A |
5: 108,465,257 (GRCm39) |
D163E |
probably damaging |
Het |
| Polq |
A |
G |
16: 36,880,586 (GRCm39) |
T638A |
possibly damaging |
Het |
| Prmt3 |
T |
A |
7: 49,448,094 (GRCm39) |
M268K |
possibly damaging |
Het |
| Prmt9 |
T |
C |
8: 78,291,737 (GRCm39) |
C370R |
probably benign |
Het |
| Prss57 |
A |
T |
10: 79,623,219 (GRCm39) |
V76E |
possibly damaging |
Het |
| Psme3ip1 |
T |
C |
8: 95,315,439 (GRCm39) |
E31G |
probably damaging |
Het |
| Qars1 |
T |
A |
9: 108,385,400 (GRCm39) |
|
probably null |
Het |
| Ralgapb |
T |
C |
2: 158,304,115 (GRCm39) |
Y625H |
probably damaging |
Het |
| Rgl2 |
G |
A |
17: 34,150,718 (GRCm39) |
D59N |
probably benign |
Het |
| Robo1 |
T |
G |
16: 72,801,555 (GRCm39) |
W1060G |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,771,830 (GRCm39) |
V362E |
probably benign |
Het |
| Schip1 |
T |
C |
3: 68,525,017 (GRCm39) |
F131S |
probably damaging |
Het |
| Sh2b2 |
A |
T |
5: 136,256,276 (GRCm39) |
V252D |
probably damaging |
Het |
| Shld2 |
C |
A |
14: 33,990,130 (GRCm39) |
V259L |
probably benign |
Het |
| Slc17a6 |
A |
T |
7: 51,295,957 (GRCm39) |
H199L |
possibly damaging |
Het |
| Slc29a1 |
A |
G |
17: 45,898,234 (GRCm39) |
Y325H |
probably damaging |
Het |
| Slc29a4 |
G |
T |
5: 142,699,817 (GRCm39) |
W156L |
probably damaging |
Het |
| Slc5a3 |
T |
A |
16: 91,874,644 (GRCm39) |
S234T |
probably benign |
Het |
| Srd5a3 |
T |
G |
5: 76,297,630 (GRCm39) |
V20G |
probably damaging |
Het |
| Stac |
A |
T |
9: 111,433,150 (GRCm39) |
S223T |
possibly damaging |
Het |
| Sytl2 |
A |
T |
7: 90,052,260 (GRCm39) |
T766S |
probably benign |
Het |
| Tas2r102 |
A |
G |
6: 132,739,254 (GRCm39) |
D54G |
probably benign |
Het |
| Tbpl1 |
A |
G |
10: 22,583,742 (GRCm39) |
V105A |
probably damaging |
Het |
| Tenm3 |
G |
T |
8: 48,870,214 (GRCm39) |
P193Q |
probably benign |
Het |
| Tes |
G |
A |
6: 17,104,754 (GRCm39) |
V403M |
probably benign |
Het |
| Tgfbr2 |
A |
C |
9: 115,938,948 (GRCm39) |
I318S |
probably damaging |
Het |
| Tgfbr3 |
C |
A |
5: 107,284,796 (GRCm39) |
V618L |
probably benign |
Het |
| Tmc1 |
C |
T |
19: 20,793,473 (GRCm39) |
|
probably null |
Het |
| Tmem132a |
G |
A |
19: 10,835,870 (GRCm39) |
H887Y |
probably damaging |
Het |
| Tmem43 |
C |
A |
6: 91,454,312 (GRCm39) |
S33* |
probably null |
Het |
| Tob1 |
A |
G |
11: 94,104,580 (GRCm39) |
K39E |
probably damaging |
Het |
| Tut7 |
A |
T |
13: 59,939,635 (GRCm39) |
H705Q |
probably damaging |
Het |
| Unc79 |
T |
A |
12: 103,078,714 (GRCm39) |
D1433E |
probably damaging |
Het |
| Usp25 |
T |
C |
16: 76,878,442 (GRCm39) |
M622T |
probably damaging |
Het |
| Vmn1r158 |
A |
T |
7: 22,489,855 (GRCm39) |
L118Q |
probably damaging |
Het |
| Vmn1r217 |
T |
A |
13: 23,298,495 (GRCm39) |
I136L |
probably benign |
Het |
| Vmn2r15 |
A |
T |
5: 109,442,136 (GRCm39) |
I99K |
possibly damaging |
Het |
| Vwa7 |
T |
A |
17: 35,243,924 (GRCm39) |
V786E |
probably damaging |
Het |
| Xkr5 |
A |
G |
8: 18,989,148 (GRCm39) |
F248S |
probably benign |
Het |
| Zzef1 |
A |
T |
11: 72,801,098 (GRCm39) |
K2444M |
probably damaging |
Het |
|
| Other mutations in Pzp |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Pzp
|
APN |
6 |
128,493,872 (GRCm39) |
missense |
probably benign |
0.25 |
|
IGL01470:Pzp
|
APN |
6 |
128,498,087 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01753:Pzp
|
APN |
6 |
128,479,146 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL01878:Pzp
|
APN |
6 |
128,472,261 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02307:Pzp
|
APN |
6 |
128,466,049 (GRCm39) |
nonsense |
probably null |
|
|
IGL02338:Pzp
|
APN |
6 |
128,463,133 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02546:Pzp
|
APN |
6 |
128,471,662 (GRCm39) |
splice site |
probably benign |
|
|
IGL02598:Pzp
|
APN |
6 |
128,464,420 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02699:Pzp
|
APN |
6 |
128,464,364 (GRCm39) |
critical splice donor site |
probably null |
|
|
lilibet
|
UTSW |
6 |
128,490,736 (GRCm39) |
missense |
probably damaging |
0.99 |
|
P4748:Pzp
|
UTSW |
6 |
128,467,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4151001:Pzp
|
UTSW |
6 |
128,502,259 (GRCm39) |
missense |
probably benign |
0.34 |
|
PIT4495001:Pzp
|
UTSW |
6 |
128,479,192 (GRCm39) |
missense |
probably benign |
|
|
R0157:Pzp
|
UTSW |
6 |
128,500,939 (GRCm39) |
nonsense |
probably null |
|
|
R0195:Pzp
|
UTSW |
6 |
128,464,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0238:Pzp
|
UTSW |
6 |
128,466,119 (GRCm39) |
splice site |
probably benign |
|
|
R0239:Pzp
|
UTSW |
6 |
128,466,119 (GRCm39) |
splice site |
probably benign |
|
|
R0271:Pzp
|
UTSW |
6 |
128,496,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0299:Pzp
|
UTSW |
6 |
128,472,293 (GRCm39) |
splice site |
probably benign |
|
|
R0744:Pzp
|
UTSW |
6 |
128,493,158 (GRCm39) |
unclassified |
probably benign |
|
|
R0968:Pzp
|
UTSW |
6 |
128,502,108 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1037:Pzp
|
UTSW |
6 |
128,496,389 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1074:Pzp
|
UTSW |
6 |
128,464,887 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1469:Pzp
|
UTSW |
6 |
128,489,319 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1469:Pzp
|
UTSW |
6 |
128,489,319 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1579:Pzp
|
UTSW |
6 |
128,500,931 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1646:Pzp
|
UTSW |
6 |
128,480,518 (GRCm39) |
missense |
probably benign |
0.33 |
|
R1770:Pzp
|
UTSW |
6 |
128,462,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1786:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R1854:Pzp
|
UTSW |
6 |
128,479,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2001:Pzp
|
UTSW |
6 |
128,493,083 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2060:Pzp
|
UTSW |
6 |
128,460,673 (GRCm39) |
missense |
probably benign |
0.45 |
|
R2081:Pzp
|
UTSW |
6 |
128,496,383 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2130:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R2131:Pzp
|
UTSW |
6 |
128,468,124 (GRCm39) |
splice site |
probably null |
|
|
R2160:Pzp
|
UTSW |
6 |
128,502,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2168:Pzp
|
UTSW |
6 |
128,465,010 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2328:Pzp
|
UTSW |
6 |
128,487,353 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2441:Pzp
|
UTSW |
6 |
128,466,731 (GRCm39) |
nonsense |
probably null |
|
|
R2866:Pzp
|
UTSW |
6 |
128,502,227 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R2869:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2869:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2870:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2873:Pzp
|
UTSW |
6 |
128,462,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2876:Pzp
|
UTSW |
6 |
128,468,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3404:Pzp
|
UTSW |
6 |
128,490,769 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4452:Pzp
|
UTSW |
6 |
128,468,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4461:Pzp
|
UTSW |
6 |
128,501,003 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5103:Pzp
|
UTSW |
6 |
128,479,192 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5193:Pzp
|
UTSW |
6 |
128,479,297 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5425:Pzp
|
UTSW |
6 |
128,466,011 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5465:Pzp
|
UTSW |
6 |
128,463,924 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5590:Pzp
|
UTSW |
6 |
128,500,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5656:Pzp
|
UTSW |
6 |
128,467,035 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5697:Pzp
|
UTSW |
6 |
128,502,152 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5854:Pzp
|
UTSW |
6 |
128,483,832 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5994:Pzp
|
UTSW |
6 |
128,468,560 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6042:Pzp
|
UTSW |
6 |
128,500,977 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R6054:Pzp
|
UTSW |
6 |
128,490,727 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6153:Pzp
|
UTSW |
6 |
128,465,979 (GRCm39) |
missense |
probably benign |
|
|
R6465:Pzp
|
UTSW |
6 |
128,468,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6719:Pzp
|
UTSW |
6 |
128,501,046 (GRCm39) |
missense |
probably benign |
0.17 |
|
R6722:Pzp
|
UTSW |
6 |
128,464,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7316:Pzp
|
UTSW |
6 |
128,490,736 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7453:Pzp
|
UTSW |
6 |
128,463,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7826:Pzp
|
UTSW |
6 |
128,464,496 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7878:Pzp
|
UTSW |
6 |
128,489,274 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R7879:Pzp
|
UTSW |
6 |
128,465,979 (GRCm39) |
missense |
probably benign |
|
|
R8113:Pzp
|
UTSW |
6 |
128,490,694 (GRCm39) |
splice site |
probably null |
|
|
R8163:Pzp
|
UTSW |
6 |
128,489,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8471:Pzp
|
UTSW |
6 |
128,464,411 (GRCm39) |
missense |
probably benign |
0.14 |
|
R8680:Pzp
|
UTSW |
6 |
128,473,009 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8795:Pzp
|
UTSW |
6 |
128,471,701 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8844:Pzp
|
UTSW |
6 |
128,500,950 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8964:Pzp
|
UTSW |
6 |
128,464,462 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9043:Pzp
|
UTSW |
6 |
128,471,742 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9172:Pzp
|
UTSW |
6 |
128,502,172 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9205:Pzp
|
UTSW |
6 |
128,473,626 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9276:Pzp
|
UTSW |
6 |
128,499,077 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9432:Pzp
|
UTSW |
6 |
128,499,128 (GRCm39) |
missense |
|
|
|
R9444:Pzp
|
UTSW |
6 |
128,487,362 (GRCm39) |
missense |
|
|
|
R9517:Pzp
|
UTSW |
6 |
128,489,117 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9721:Pzp
|
UTSW |
6 |
128,472,154 (GRCm39) |
critical splice donor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCCGAGTTATGTCATCGGGACTGG -3'
(R):5'- AAATGAGCCCTGCTGAACCGTGTC -3'
Sequencing Primer
(F):5'- aagaggggggcattggg -3'
(R):5'- TGCTGAACCGTGTCCACAG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation