Incidental Mutation 'R1777:Dscaml1'
| ID |
197135 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dscaml1
|
| Ensembl Gene |
ENSMUSG00000032087 |
| Gene Name |
DS cell adhesion molecule like 1 |
| Synonyms |
4921507G06Rik, 4930435C18Rik |
| MMRRC Submission |
039808-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.416)
|
| Stock # |
R1777 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
9 |
| Chromosomal Location |
45338735-45665011 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 45595054 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Proline
at position 719
(L719P)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000034592
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000034592]
|
| AlphaFold |
Q4VA61 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000034592
AA Change: L719P
PolyPhen 2
Score 0.576 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000034592
Gene: ENSMUSG00000032087
AA Change: L719P
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
17 |
N/A |
INTRINSIC |
|
low complexity region
|
28 |
55 |
N/A |
INTRINSIC |
|
IG_like
|
96 |
168 |
1.22e0 |
SMART |
|
IG
|
189 |
277 |
1.15e-3 |
SMART |
|
IGc2
|
296 |
359 |
2.54e-14 |
SMART |
|
IGc2
|
385 |
451 |
8.12e-13 |
SMART |
|
IGc2
|
478 |
550 |
9.55e-10 |
SMART |
|
IGc2
|
575 |
640 |
9.78e-7 |
SMART |
|
IGc2
|
666 |
734 |
5.93e-6 |
SMART |
|
IGc2
|
760 |
832 |
6.75e-10 |
SMART |
|
IG
|
853 |
943 |
1e-3 |
SMART |
|
FN3
|
945 |
1029 |
6.64e-7 |
SMART |
|
FN3
|
1045 |
1133 |
9.46e-12 |
SMART |
|
FN3
|
1148 |
1234 |
3.2e-9 |
SMART |
|
FN3
|
1249 |
1332 |
3.48e-10 |
SMART |
|
IGc2
|
1363 |
1428 |
1.49e-11 |
SMART |
|
FN3
|
1442 |
1522 |
3.42e-9 |
SMART |
|
FN3
|
1537 |
1618 |
2.14e-1 |
SMART |
|
low complexity region
|
1671 |
1683 |
N/A |
INTRINSIC |
|
low complexity region
|
2018 |
2026 |
N/A |
INTRINSIC |
|
low complexity region
|
2035 |
2069 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000216078
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.1%
- 20x: 92.1%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the Ig superfamily of cell adhesion molecules and is involved in neuronal differentiation. The encoded membrane-bound protein localizes to the cell surface, where it forms aggregates that repel neuronal processes of the same cell type. [provided by RefSeq, Sep 2016]
PHENOTYPE: Mice homozygous for a gene trapped allele exhibit impaired self-avoidance in multiple cell types in the retina. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Gene trapped(4) |
| Other mutations in this stock |
Total: 91 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930444P10Rik |
T |
A |
1: 16,148,813 (GRCm39) |
D111V |
possibly damaging |
Het |
| Ap2a1 |
G |
A |
7: 44,553,576 (GRCm39) |
T597M |
probably damaging |
Het |
| Arhgap25 |
A |
G |
6: 87,440,289 (GRCm39) |
S364P |
probably benign |
Het |
| Atp6v1a |
G |
T |
16: 43,935,068 (GRCm39) |
Y40* |
probably null |
Het |
| Cdh1 |
T |
A |
8: 107,383,467 (GRCm39) |
H235Q |
probably damaging |
Het |
| Cntln |
A |
G |
4: 85,048,916 (GRCm39) |
E1376G |
probably benign |
Het |
| Cntnap5b |
T |
A |
1: 100,297,803 (GRCm39) |
S781T |
probably benign |
Het |
| Cpne4 |
A |
G |
9: 104,749,887 (GRCm39) |
T64A |
probably damaging |
Het |
| Ctsg |
T |
C |
14: 56,338,058 (GRCm39) |
Y179C |
probably damaging |
Het |
| Cx3cr1 |
A |
G |
9: 119,880,659 (GRCm39) |
Y248H |
probably damaging |
Het |
| Dhx37 |
T |
C |
5: 125,506,995 (GRCm39) |
E167G |
probably benign |
Het |
| Dnajc21 |
C |
A |
15: 10,449,693 (GRCm39) |
A443S |
probably benign |
Het |
| Drd5 |
T |
C |
5: 38,477,504 (GRCm39) |
S166P |
probably damaging |
Het |
| Eif2ak4 |
T |
C |
2: 118,261,320 (GRCm39) |
I542T |
probably damaging |
Het |
| Ephb3 |
G |
A |
16: 21,035,985 (GRCm39) |
G291E |
probably damaging |
Het |
| Eva1a |
T |
A |
6: 82,069,137 (GRCm39) |
Y155N |
probably damaging |
Het |
| Exog |
C |
T |
9: 119,278,884 (GRCm39) |
P189L |
probably damaging |
Het |
| Fam13b |
A |
G |
18: 34,590,813 (GRCm39) |
V455A |
possibly damaging |
Het |
| Fmn2 |
C |
A |
1: 174,409,488 (GRCm39) |
Q574K |
unknown |
Het |
| Gm6871 |
A |
T |
7: 41,195,143 (GRCm39) |
S531R |
probably benign |
Het |
| Golga2 |
T |
A |
2: 32,195,482 (GRCm39) |
|
probably null |
Het |
| Hydin |
C |
T |
8: 111,316,203 (GRCm39) |
P4365L |
probably benign |
Het |
| Ints8 |
A |
T |
4: 11,225,600 (GRCm39) |
|
probably null |
Het |
| Kbtbd12 |
A |
C |
6: 88,595,042 (GRCm39) |
S263A |
probably benign |
Het |
| Kcng4 |
T |
C |
8: 120,360,226 (GRCm39) |
D50G |
probably benign |
Het |
| Klhl18 |
A |
T |
9: 110,266,469 (GRCm39) |
C217S |
probably benign |
Het |
| Klk1b4 |
A |
G |
7: 43,856,875 (GRCm39) |
|
probably benign |
Het |
| Klk7 |
G |
A |
7: 43,462,753 (GRCm39) |
C186Y |
probably damaging |
Het |
| Krbox5 |
A |
T |
13: 67,981,984 (GRCm39) |
R65S |
probably benign |
Het |
| Krit1 |
T |
C |
5: 3,886,799 (GRCm39) |
Y635H |
probably damaging |
Het |
| Lipo4 |
A |
T |
19: 33,476,721 (GRCm39) |
D342E |
probably damaging |
Het |
| Lsm14b |
T |
G |
2: 179,673,588 (GRCm39) |
D199E |
probably benign |
Het |
| Map3k4 |
A |
T |
17: 12,490,617 (GRCm39) |
N271K |
possibly damaging |
Het |
| Mast1 |
T |
A |
8: 85,638,697 (GRCm39) |
N1544I |
probably benign |
Het |
| Megf6 |
T |
A |
4: 154,355,147 (GRCm39) |
C1487* |
probably null |
Het |
| Mlh3 |
C |
A |
12: 85,315,528 (GRCm39) |
K219N |
possibly damaging |
Het |
| Mtmr4 |
A |
G |
11: 87,493,656 (GRCm39) |
K305E |
probably damaging |
Het |
| Myo15a |
A |
G |
11: 60,405,762 (GRCm39) |
M3105V |
probably benign |
Het |
| Nbas |
A |
T |
12: 13,563,563 (GRCm39) |
I1958F |
probably benign |
Het |
| Nepro |
A |
T |
16: 44,556,216 (GRCm39) |
Q458L |
probably damaging |
Het |
| Opa3 |
T |
C |
7: 18,978,837 (GRCm39) |
Y101H |
probably damaging |
Het |
| Or11g25 |
T |
A |
14: 50,723,757 (GRCm39) |
F281I |
probably benign |
Het |
| Or14c41 |
T |
A |
7: 86,235,272 (GRCm39) |
I263N |
probably benign |
Het |
| Or4f15 |
T |
A |
2: 111,814,042 (GRCm39) |
I126L |
possibly damaging |
Het |
| Or51f1d |
T |
C |
7: 102,700,583 (GRCm39) |
I26T |
probably benign |
Het |
| Or5ac16 |
A |
G |
16: 59,022,379 (GRCm39) |
S137P |
probably benign |
Het |
| Or8b12 |
A |
G |
9: 37,657,607 (GRCm39) |
Y59C |
possibly damaging |
Het |
| Pate3 |
T |
C |
9: 35,559,412 (GRCm39) |
N2D |
probably benign |
Het |
| Pcdhb21 |
T |
A |
18: 37,648,771 (GRCm39) |
D633E |
possibly damaging |
Het |
| Pgm2 |
C |
T |
5: 64,285,125 (GRCm39) |
P589L |
probably benign |
Het |
| Pigg |
T |
A |
5: 108,465,257 (GRCm39) |
D163E |
probably damaging |
Het |
| Polq |
A |
G |
16: 36,880,586 (GRCm39) |
T638A |
possibly damaging |
Het |
| Prmt3 |
T |
A |
7: 49,448,094 (GRCm39) |
M268K |
possibly damaging |
Het |
| Prmt9 |
T |
C |
8: 78,291,737 (GRCm39) |
C370R |
probably benign |
Het |
| Prss57 |
A |
T |
10: 79,623,219 (GRCm39) |
V76E |
possibly damaging |
Het |
| Psme3ip1 |
T |
C |
8: 95,315,439 (GRCm39) |
E31G |
probably damaging |
Het |
| Pzp |
T |
C |
6: 128,467,535 (GRCm39) |
E1089G |
possibly damaging |
Het |
| Qars1 |
T |
A |
9: 108,385,400 (GRCm39) |
|
probably null |
Het |
| Ralgapb |
T |
C |
2: 158,304,115 (GRCm39) |
Y625H |
probably damaging |
Het |
| Rgl2 |
G |
A |
17: 34,150,718 (GRCm39) |
D59N |
probably benign |
Het |
| Robo1 |
T |
G |
16: 72,801,555 (GRCm39) |
W1060G |
probably benign |
Het |
| Scaper |
A |
T |
9: 55,771,830 (GRCm39) |
V362E |
probably benign |
Het |
| Schip1 |
T |
C |
3: 68,525,017 (GRCm39) |
F131S |
probably damaging |
Het |
| Sh2b2 |
A |
T |
5: 136,256,276 (GRCm39) |
V252D |
probably damaging |
Het |
| Shld2 |
C |
A |
14: 33,990,130 (GRCm39) |
V259L |
probably benign |
Het |
| Slc17a6 |
A |
T |
7: 51,295,957 (GRCm39) |
H199L |
possibly damaging |
Het |
| Slc29a1 |
A |
G |
17: 45,898,234 (GRCm39) |
Y325H |
probably damaging |
Het |
| Slc29a4 |
G |
T |
5: 142,699,817 (GRCm39) |
W156L |
probably damaging |
Het |
| Slc5a3 |
T |
A |
16: 91,874,644 (GRCm39) |
S234T |
probably benign |
Het |
| Srd5a3 |
T |
G |
5: 76,297,630 (GRCm39) |
V20G |
probably damaging |
Het |
| Stac |
A |
T |
9: 111,433,150 (GRCm39) |
S223T |
possibly damaging |
Het |
| Sytl2 |
A |
T |
7: 90,052,260 (GRCm39) |
T766S |
probably benign |
Het |
| Tas2r102 |
A |
G |
6: 132,739,254 (GRCm39) |
D54G |
probably benign |
Het |
| Tbpl1 |
A |
G |
10: 22,583,742 (GRCm39) |
V105A |
probably damaging |
Het |
| Tenm3 |
G |
T |
8: 48,870,214 (GRCm39) |
P193Q |
probably benign |
Het |
| Tes |
G |
A |
6: 17,104,754 (GRCm39) |
V403M |
probably benign |
Het |
| Tgfbr2 |
A |
C |
9: 115,938,948 (GRCm39) |
I318S |
probably damaging |
Het |
| Tgfbr3 |
C |
A |
5: 107,284,796 (GRCm39) |
V618L |
probably benign |
Het |
| Tmc1 |
C |
T |
19: 20,793,473 (GRCm39) |
|
probably null |
Het |
| Tmem132a |
G |
A |
19: 10,835,870 (GRCm39) |
H887Y |
probably damaging |
Het |
| Tmem43 |
C |
A |
6: 91,454,312 (GRCm39) |
S33* |
probably null |
Het |
| Tob1 |
A |
G |
11: 94,104,580 (GRCm39) |
K39E |
probably damaging |
Het |
| Tut7 |
A |
T |
13: 59,939,635 (GRCm39) |
H705Q |
probably damaging |
Het |
| Unc79 |
T |
A |
12: 103,078,714 (GRCm39) |
D1433E |
probably damaging |
Het |
| Usp25 |
T |
C |
16: 76,878,442 (GRCm39) |
M622T |
probably damaging |
Het |
| Vmn1r158 |
A |
T |
7: 22,489,855 (GRCm39) |
L118Q |
probably damaging |
Het |
| Vmn1r217 |
T |
A |
13: 23,298,495 (GRCm39) |
I136L |
probably benign |
Het |
| Vmn2r15 |
A |
T |
5: 109,442,136 (GRCm39) |
I99K |
possibly damaging |
Het |
| Vwa7 |
T |
A |
17: 35,243,924 (GRCm39) |
V786E |
probably damaging |
Het |
| Xkr5 |
A |
G |
8: 18,989,148 (GRCm39) |
F248S |
probably benign |
Het |
| Zzef1 |
A |
T |
11: 72,801,098 (GRCm39) |
K2444M |
probably damaging |
Het |
|
| Other mutations in Dscaml1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00418:Dscaml1
|
APN |
9 |
45,581,498 (GRCm39) |
nonsense |
probably null |
|
|
IGL00497:Dscaml1
|
APN |
9 |
45,663,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00895:Dscaml1
|
APN |
9 |
45,662,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01011:Dscaml1
|
APN |
9 |
45,594,970 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01086:Dscaml1
|
APN |
9 |
45,613,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL01125:Dscaml1
|
APN |
9 |
45,660,930 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL01132:Dscaml1
|
APN |
9 |
45,663,626 (GRCm39) |
nonsense |
probably null |
|
|
IGL01356:Dscaml1
|
APN |
9 |
45,658,155 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01459:Dscaml1
|
APN |
9 |
45,653,981 (GRCm39) |
nonsense |
probably null |
|
|
IGL01552:Dscaml1
|
APN |
9 |
45,359,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02033:Dscaml1
|
APN |
9 |
45,595,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02044:Dscaml1
|
APN |
9 |
45,658,241 (GRCm39) |
nonsense |
probably null |
|
|
IGL02095:Dscaml1
|
APN |
9 |
45,359,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02166:Dscaml1
|
APN |
9 |
45,594,999 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,643,378 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL02262:Dscaml1
|
APN |
9 |
45,656,414 (GRCm39) |
missense |
probably benign |
|
|
IGL02340:Dscaml1
|
APN |
9 |
45,581,474 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02604:Dscaml1
|
APN |
9 |
45,655,626 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02619:Dscaml1
|
APN |
9 |
45,359,094 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02805:Dscaml1
|
APN |
9 |
45,359,195 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03409:Dscaml1
|
APN |
9 |
45,581,401 (GRCm39) |
missense |
probably damaging |
1.00 |
|
D3080:Dscaml1
|
UTSW |
9 |
45,595,623 (GRCm39) |
missense |
probably benign |
0.44 |
|
IGL03050:Dscaml1
|
UTSW |
9 |
45,654,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0149:Dscaml1
|
UTSW |
9 |
45,653,978 (GRCm39) |
nonsense |
probably null |
|
|
R0582:Dscaml1
|
UTSW |
9 |
45,579,562 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R0629:Dscaml1
|
UTSW |
9 |
45,632,716 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0632:Dscaml1
|
UTSW |
9 |
45,643,432 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0815:Dscaml1
|
UTSW |
9 |
45,656,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1162:Dscaml1
|
UTSW |
9 |
45,663,647 (GRCm39) |
splice site |
probably benign |
|
|
R1449:Dscaml1
|
UTSW |
9 |
45,653,521 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1474:Dscaml1
|
UTSW |
9 |
45,596,519 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1481:Dscaml1
|
UTSW |
9 |
45,583,941 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1533:Dscaml1
|
UTSW |
9 |
45,361,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1542:Dscaml1
|
UTSW |
9 |
45,660,738 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1572:Dscaml1
|
UTSW |
9 |
45,632,631 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1627:Dscaml1
|
UTSW |
9 |
45,664,445 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1634:Dscaml1
|
UTSW |
9 |
45,584,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Dscaml1
|
UTSW |
9 |
45,663,988 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R1812:Dscaml1
|
UTSW |
9 |
45,662,584 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1834:Dscaml1
|
UTSW |
9 |
45,594,930 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1907:Dscaml1
|
UTSW |
9 |
45,651,778 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1953:Dscaml1
|
UTSW |
9 |
45,581,522 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2056:Dscaml1
|
UTSW |
9 |
45,661,430 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2193:Dscaml1
|
UTSW |
9 |
45,596,532 (GRCm39) |
missense |
probably benign |
0.21 |
|
R2497:Dscaml1
|
UTSW |
9 |
45,656,376 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3768:Dscaml1
|
UTSW |
9 |
45,643,435 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3891:Dscaml1
|
UTSW |
9 |
45,628,782 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4110:Dscaml1
|
UTSW |
9 |
45,643,366 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4706:Dscaml1
|
UTSW |
9 |
45,361,878 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4716:Dscaml1
|
UTSW |
9 |
45,361,890 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4719:Dscaml1
|
UTSW |
9 |
45,583,993 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4770:Dscaml1
|
UTSW |
9 |
45,581,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4924:Dscaml1
|
UTSW |
9 |
45,656,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5167:Dscaml1
|
UTSW |
9 |
45,628,730 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5346:Dscaml1
|
UTSW |
9 |
45,361,857 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5737:Dscaml1
|
UTSW |
9 |
45,656,483 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5977:Dscaml1
|
UTSW |
9 |
45,632,596 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6073:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6276:Dscaml1
|
UTSW |
9 |
45,579,458 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6415:Dscaml1
|
UTSW |
9 |
45,594,975 (GRCm39) |
nonsense |
probably null |
|
|
R6527:Dscaml1
|
UTSW |
9 |
45,623,482 (GRCm39) |
nonsense |
probably null |
|
|
R6582:Dscaml1
|
UTSW |
9 |
45,664,104 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6655:Dscaml1
|
UTSW |
9 |
45,658,235 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6772:Dscaml1
|
UTSW |
9 |
45,621,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6799:Dscaml1
|
UTSW |
9 |
45,361,881 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6892:Dscaml1
|
UTSW |
9 |
45,595,128 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6918:Dscaml1
|
UTSW |
9 |
45,341,805 (GRCm39) |
missense |
probably benign |
|
|
R6967:Dscaml1
|
UTSW |
9 |
45,585,821 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7214:Dscaml1
|
UTSW |
9 |
45,581,437 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7286:Dscaml1
|
UTSW |
9 |
45,654,044 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7315:Dscaml1
|
UTSW |
9 |
45,656,423 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7338:Dscaml1
|
UTSW |
9 |
45,585,802 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7343:Dscaml1
|
UTSW |
9 |
45,664,214 (GRCm39) |
missense |
probably benign |
|
|
R7395:Dscaml1
|
UTSW |
9 |
45,613,703 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R7439:Dscaml1
|
UTSW |
9 |
45,621,624 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7484:Dscaml1
|
UTSW |
9 |
45,660,744 (GRCm39) |
splice site |
probably null |
|
|
R7545:Dscaml1
|
UTSW |
9 |
45,596,681 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7979:Dscaml1
|
UTSW |
9 |
45,595,029 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:Dscaml1
|
UTSW |
9 |
45,628,808 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8181:Dscaml1
|
UTSW |
9 |
45,658,140 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R8262:Dscaml1
|
UTSW |
9 |
45,658,438 (GRCm39) |
intron |
probably benign |
|
|
R8428:Dscaml1
|
UTSW |
9 |
45,653,884 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8725:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8727:Dscaml1
|
UTSW |
9 |
45,341,759 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8796:Dscaml1
|
UTSW |
9 |
45,359,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8840:Dscaml1
|
UTSW |
9 |
45,634,718 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9291:Dscaml1
|
UTSW |
9 |
45,359,251 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9394:Dscaml1
|
UTSW |
9 |
45,661,354 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R9610:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9611:Dscaml1
|
UTSW |
9 |
45,579,522 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R9653:Dscaml1
|
UTSW |
9 |
45,643,466 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9699:Dscaml1
|
UTSW |
9 |
45,654,315 (GRCm39) |
missense |
probably damaging |
0.97 |
|
X0058:Dscaml1
|
UTSW |
9 |
45,663,426 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Dscaml1
|
UTSW |
9 |
45,584,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TCTGAGAGCCGGGAAGACTAACAC -3'
(R):5'- TGTCTTTAAGAAGCCATCCAGCACC -3'
Sequencing Primer
(F):5'- TGGAGAGCTACACTCTAGCC -3'
(R):5'- CCATCCAGCACCAACCTC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation