Incidental Mutation 'R1778:Nup210l'
| ID |
197207 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nup210l
|
| Ensembl Gene |
ENSMUSG00000027939 |
| Gene Name |
nucleoporin 210-like |
| Synonyms |
4930548O11Rik |
| MMRRC Submission |
039809-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.427)
|
| Stock # |
R1778 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
90011439-90119355 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 90096793 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 1334
(E1334G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143368
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029548]
[ENSMUST00000200410]
|
| AlphaFold |
Q9D2F7 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029548
AA Change: E1334G
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000029548
Gene: ENSMUSG00000027939
AA Change: E1334G
| Domain | Start | End | E-Value | Type |
|---|
|
transmembrane domain
|
13 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
2.05e1 |
SMART |
|
Blast:S1
|
949 |
1023 |
2e-16 |
BLAST |
|
BID_2
|
1077 |
1152 |
4.51e-11 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000200410
AA Change: E1334G
PolyPhen 2
Score 0.987 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000143368
Gene: ENSMUSG00000027939
AA Change: E1334G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
32 |
N/A |
INTRINSIC |
|
BID_2
|
457 |
536 |
6.9e-2 |
SMART |
|
Blast:S1
|
938 |
1023 |
9e-17 |
BLAST |
|
BID_2
|
1077 |
1152 |
1.5e-13 |
SMART |
|
Blast:BID_2
|
1468 |
1550 |
7e-15 |
BLAST |
|
transmembrane domain
|
1807 |
1829 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1065 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 97.0%
- 10x: 95.6%
- 20x: 93.3%
|
| Validation Efficiency |
98% (107/109) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a transgene insertion exhibit male infertility, asthenozoospermia, teratozoospermia, azoospermia, and seminiferous tubule degeneration. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 105 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930432E11Rik |
T |
C |
7: 29,260,131 (GRCm39) |
|
noncoding transcript |
Het |
| 4930568D16Rik |
A |
G |
2: 35,244,995 (GRCm39) |
M119T |
probably damaging |
Het |
| Aadacl2 |
A |
G |
3: 59,924,871 (GRCm39) |
|
probably null |
Het |
| Abca9 |
C |
T |
11: 110,021,542 (GRCm39) |
W1056* |
probably null |
Het |
| Adam20 |
A |
C |
8: 41,249,698 (GRCm39) |
T603P |
possibly damaging |
Het |
| Adgrl1 |
T |
C |
8: 84,656,666 (GRCm39) |
L323P |
probably damaging |
Het |
| Afap1l2 |
C |
T |
19: 56,904,638 (GRCm39) |
E628K |
possibly damaging |
Het |
| Ahctf1 |
A |
T |
1: 179,580,580 (GRCm39) |
L1874Q |
possibly damaging |
Het |
| Ak8 |
A |
G |
2: 28,602,333 (GRCm39) |
E89G |
probably benign |
Het |
| Aldh16a1 |
G |
A |
7: 44,796,732 (GRCm39) |
R256C |
probably damaging |
Het |
| Anxa5 |
G |
A |
3: 36,519,480 (GRCm39) |
T3M |
probably damaging |
Het |
| Arhgef16 |
T |
C |
4: 154,372,443 (GRCm39) |
K210E |
probably benign |
Het |
| Baz2b |
T |
C |
2: 59,836,480 (GRCm39) |
T18A |
unknown |
Het |
| Bub1 |
A |
C |
2: 127,645,042 (GRCm39) |
I960M |
possibly damaging |
Het |
| Cbln2 |
G |
T |
18: 86,731,272 (GRCm39) |
D27Y |
probably benign |
Het |
| Ces2h |
C |
A |
8: 105,741,239 (GRCm39) |
P77Q |
possibly damaging |
Het |
| Cfap410 |
G |
T |
10: 77,818,778 (GRCm39) |
A150S |
probably benign |
Het |
| Chga |
T |
A |
12: 102,527,959 (GRCm39) |
M150K |
probably benign |
Het |
| Chmp3 |
A |
G |
6: 71,554,791 (GRCm39) |
E162G |
probably benign |
Het |
| Clip3 |
A |
G |
7: 29,996,861 (GRCm39) |
N161S |
probably damaging |
Het |
| Col12a1 |
T |
A |
9: 79,511,867 (GRCm39) |
|
probably benign |
Het |
| Cuedc2 |
C |
T |
19: 46,320,079 (GRCm39) |
G105D |
probably benign |
Het |
| Cyp2j7 |
A |
C |
4: 96,087,627 (GRCm39) |
F428V |
probably damaging |
Het |
| Ddx60 |
A |
G |
8: 62,427,210 (GRCm39) |
I762V |
possibly damaging |
Het |
| Def6 |
G |
A |
17: 28,439,160 (GRCm39) |
R257Q |
probably benign |
Het |
| Dkkl1 |
A |
T |
7: 44,860,819 (GRCm39) |
|
probably null |
Het |
| Dnah3 |
A |
G |
7: 119,677,625 (GRCm39) |
L433P |
probably damaging |
Het |
| Eif2s3y |
C |
T |
Y: 1,011,287 (GRCm39) |
R33C |
probably benign |
Het |
| Elavl2 |
T |
A |
4: 91,141,715 (GRCm39) |
Y269F |
probably damaging |
Het |
| Esco2 |
A |
G |
14: 66,068,711 (GRCm39) |
S200P |
possibly damaging |
Het |
| Fcrl1 |
T |
A |
3: 87,292,626 (GRCm39) |
|
probably benign |
Het |
| Fhod1 |
C |
A |
8: 106,056,309 (GRCm39) |
D1135Y |
probably damaging |
Het |
| Fnbp1l |
T |
C |
3: 122,383,796 (GRCm39) |
N41D |
possibly damaging |
Het |
| Folh1 |
A |
T |
7: 86,410,907 (GRCm39) |
|
probably null |
Het |
| Fpr-rs7 |
T |
C |
17: 20,334,277 (GRCm39) |
D71G |
probably damaging |
Het |
| Gm10271 |
A |
G |
10: 116,797,844 (GRCm39) |
|
probably benign |
Het |
| Gm4841 |
A |
T |
18: 60,404,020 (GRCm39) |
Y24* |
probably null |
Het |
| Greb1 |
G |
A |
12: 16,740,895 (GRCm39) |
R1396C |
probably benign |
Het |
| Hectd1 |
C |
T |
12: 51,800,590 (GRCm39) |
C2076Y |
probably damaging |
Het |
| Hnrnpu |
A |
G |
1: 178,152,806 (GRCm39) |
|
probably benign |
Het |
| Ice2 |
T |
C |
9: 69,322,930 (GRCm39) |
I475T |
probably benign |
Het |
| Ifit1bl1 |
T |
A |
19: 34,571,593 (GRCm39) |
Q288L |
probably damaging |
Het |
| Ift56 |
T |
A |
6: 38,386,411 (GRCm39) |
D377E |
possibly damaging |
Het |
| Ik |
T |
C |
18: 36,889,871 (GRCm39) |
|
probably benign |
Het |
| Kidins220 |
C |
T |
12: 25,063,445 (GRCm39) |
|
probably benign |
Het |
| Kmt2c |
T |
C |
5: 25,577,972 (GRCm39) |
D768G |
probably benign |
Het |
| Kmt2e |
A |
G |
5: 23,697,362 (GRCm39) |
T87A |
probably damaging |
Het |
| Lama5 |
G |
A |
2: 179,837,274 (GRCm39) |
|
probably benign |
Het |
| Lmbr1l |
A |
G |
15: 98,810,357 (GRCm39) |
S85P |
probably damaging |
Het |
| Lrig2 |
A |
G |
3: 104,374,682 (GRCm39) |
|
probably benign |
Het |
| Lrig3 |
A |
G |
10: 125,845,944 (GRCm39) |
D791G |
probably damaging |
Het |
| Lrrc2 |
G |
A |
9: 110,809,908 (GRCm39) |
V315M |
probably benign |
Het |
| Lrrc4b |
A |
G |
7: 44,111,823 (GRCm39) |
D565G |
probably benign |
Het |
| Mpped1 |
C |
T |
15: 83,676,191 (GRCm39) |
|
probably benign |
Het |
| Msrb2 |
T |
A |
2: 19,388,114 (GRCm39) |
D87E |
probably benign |
Het |
| Muc20 |
T |
C |
16: 32,614,511 (GRCm39) |
T289A |
possibly damaging |
Het |
| Myo15a |
C |
A |
11: 60,369,238 (GRCm39) |
P666Q |
possibly damaging |
Het |
| Nfat5 |
C |
T |
8: 108,088,421 (GRCm39) |
P579L |
probably damaging |
Het |
| Nipbl |
A |
C |
15: 8,348,972 (GRCm39) |
M1920R |
probably damaging |
Het |
| Nuak1 |
T |
C |
10: 84,210,738 (GRCm39) |
|
probably null |
Het |
| Odad2 |
A |
T |
18: 7,127,388 (GRCm39) |
C942S |
probably damaging |
Het |
| Or52e8b |
A |
T |
7: 104,673,370 (GRCm39) |
N272K |
probably benign |
Het |
| Or5an1c |
T |
A |
19: 12,218,819 (GRCm39) |
I69F |
probably benign |
Het |
| Or6c6c |
T |
C |
10: 129,541,574 (GRCm39) |
Y276H |
probably benign |
Het |
| Or9s13 |
G |
A |
1: 92,548,342 (GRCm39) |
G238E |
possibly damaging |
Het |
| Or9s14 |
A |
T |
1: 92,535,831 (GRCm39) |
N91Y |
possibly damaging |
Het |
| P4ha3 |
A |
T |
7: 99,949,898 (GRCm39) |
|
probably null |
Het |
| Pbld2 |
C |
T |
10: 62,890,150 (GRCm39) |
A186V |
probably benign |
Het |
| Pcdh18 |
A |
T |
3: 49,710,083 (GRCm39) |
Y411N |
probably benign |
Het |
| Pgf |
A |
G |
12: 85,218,541 (GRCm39) |
S70P |
probably benign |
Het |
| Phrf1 |
T |
A |
7: 140,812,369 (GRCm39) |
D44E |
probably benign |
Het |
| Pla2g4a |
A |
G |
1: 149,778,196 (GRCm39) |
|
probably benign |
Het |
| Plce1 |
A |
G |
19: 38,769,234 (GRCm39) |
|
probably benign |
Het |
| Plxna2 |
A |
G |
1: 194,493,278 (GRCm39) |
N1851S |
probably benign |
Het |
| Prl7a2 |
G |
A |
13: 27,843,254 (GRCm39) |
T183I |
probably damaging |
Het |
| Prxl2b |
A |
T |
4: 154,981,814 (GRCm39) |
V151D |
probably damaging |
Het |
| Ptger4 |
A |
T |
15: 5,264,576 (GRCm39) |
L335H |
probably damaging |
Het |
| Ptgr1 |
A |
G |
4: 58,984,865 (GRCm39) |
|
probably benign |
Het |
| Rdh7 |
A |
G |
10: 127,720,590 (GRCm39) |
S261P |
probably benign |
Het |
| Reg3a |
A |
G |
6: 78,360,269 (GRCm39) |
T150A |
probably benign |
Het |
| Rnf111 |
A |
G |
9: 70,383,394 (GRCm39) |
S180P |
probably benign |
Het |
| Rnf17 |
A |
G |
14: 56,759,856 (GRCm39) |
M1554V |
probably damaging |
Het |
| Rnf215 |
T |
A |
11: 4,085,873 (GRCm39) |
Y117* |
probably null |
Het |
| Rnps1-ps |
A |
T |
6: 7,983,124 (GRCm39) |
|
noncoding transcript |
Het |
| Rogdi |
T |
C |
16: 4,828,369 (GRCm39) |
T165A |
probably benign |
Het |
| Rpe65 |
A |
G |
3: 159,328,485 (GRCm39) |
Y431C |
probably damaging |
Het |
| Scube1 |
A |
G |
15: 83,494,405 (GRCm39) |
F844S |
probably damaging |
Het |
| Sdr16c6 |
T |
A |
4: 4,058,814 (GRCm39) |
E257D |
probably benign |
Het |
| Sim1 |
C |
A |
10: 50,857,649 (GRCm39) |
C466* |
probably null |
Het |
| Spi1 |
T |
A |
2: 90,929,867 (GRCm39) |
H46Q |
probably damaging |
Het |
| Sumf2 |
C |
A |
5: 129,873,909 (GRCm39) |
|
probably benign |
Het |
| Tbcb |
A |
G |
7: 29,931,037 (GRCm39) |
Y28H |
probably benign |
Het |
| Tecta |
C |
T |
9: 42,254,927 (GRCm39) |
C1752Y |
probably damaging |
Het |
| Tep1 |
T |
C |
14: 51,067,079 (GRCm39) |
|
probably benign |
Het |
| Tmem245 |
A |
T |
4: 56,903,968 (GRCm39) |
W591R |
probably damaging |
Het |
| Tnxb |
A |
G |
17: 34,902,548 (GRCm39) |
I1134V |
probably benign |
Het |
| Trappc14 |
T |
C |
5: 138,260,739 (GRCm39) |
|
probably null |
Het |
| Trim13 |
G |
T |
14: 61,843,068 (GRCm39) |
A362S |
probably benign |
Het |
| Trim47 |
T |
A |
11: 116,000,646 (GRCm39) |
D134V |
probably damaging |
Het |
| Utrn |
C |
A |
10: 12,312,108 (GRCm39) |
D616Y |
probably damaging |
Het |
| Vnn1 |
G |
T |
10: 23,775,415 (GRCm39) |
A222S |
possibly damaging |
Het |
| Wdr17 |
A |
G |
8: 55,143,249 (GRCm39) |
W110R |
probably damaging |
Het |
| Wwp1 |
G |
T |
4: 19,627,892 (GRCm39) |
Y700* |
probably null |
Het |
| Zbtb21 |
T |
C |
16: 97,751,785 (GRCm39) |
S661G |
probably benign |
Het |
| Zfp955b |
A |
G |
17: 33,521,788 (GRCm39) |
K419R |
probably benign |
Het |
|
| Other mutations in Nup210l |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00780:Nup210l
|
APN |
3 |
90,098,156 (GRCm39) |
splice site |
probably benign |
|
|
IGL00813:Nup210l
|
APN |
3 |
90,039,725 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01375:Nup210l
|
APN |
3 |
90,067,200 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01731:Nup210l
|
APN |
3 |
90,061,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01786:Nup210l
|
APN |
3 |
90,030,083 (GRCm39) |
nonsense |
probably null |
|
|
IGL01958:Nup210l
|
APN |
3 |
90,111,231 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
IGL02094:Nup210l
|
APN |
3 |
90,087,520 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02120:Nup210l
|
APN |
3 |
90,044,169 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02313:Nup210l
|
APN |
3 |
90,030,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02336:Nup210l
|
APN |
3 |
90,088,859 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02348:Nup210l
|
APN |
3 |
90,011,471 (GRCm39) |
utr 5 prime |
probably benign |
|
|
IGL02372:Nup210l
|
APN |
3 |
90,109,278 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02557:Nup210l
|
APN |
3 |
90,031,537 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02559:Nup210l
|
APN |
3 |
90,067,260 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02738:Nup210l
|
APN |
3 |
90,044,157 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL03231:Nup210l
|
APN |
3 |
90,096,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Nup210l
|
APN |
3 |
90,087,455 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03388:Nup210l
|
APN |
3 |
90,077,351 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03134:Nup210l
|
UTSW |
3 |
90,098,194 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0003:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0040:Nup210l
|
UTSW |
3 |
90,089,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0083:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0090:Nup210l
|
UTSW |
3 |
90,119,086 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0108:Nup210l
|
UTSW |
3 |
90,096,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0142:Nup210l
|
UTSW |
3 |
90,079,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Nup210l
|
UTSW |
3 |
90,114,675 (GRCm39) |
missense |
probably benign |
0.13 |
|
R0332:Nup210l
|
UTSW |
3 |
90,039,616 (GRCm39) |
splice site |
probably benign |
|
|
R0346:Nup210l
|
UTSW |
3 |
90,096,745 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0463:Nup210l
|
UTSW |
3 |
90,087,518 (GRCm39) |
missense |
probably null |
1.00 |
|
R0622:Nup210l
|
UTSW |
3 |
90,075,047 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0765:Nup210l
|
UTSW |
3 |
90,027,184 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0990:Nup210l
|
UTSW |
3 |
90,119,232 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1014:Nup210l
|
UTSW |
3 |
90,077,355 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1036:Nup210l
|
UTSW |
3 |
90,100,247 (GRCm39) |
splice site |
probably benign |
|
|
R1177:Nup210l
|
UTSW |
3 |
90,109,310 (GRCm39) |
missense |
probably benign |
0.11 |
|
R1183:Nup210l
|
UTSW |
3 |
90,067,252 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1188:Nup210l
|
UTSW |
3 |
90,105,486 (GRCm39) |
missense |
probably benign |
0.16 |
|
R1457:Nup210l
|
UTSW |
3 |
90,098,279 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1471:Nup210l
|
UTSW |
3 |
90,077,869 (GRCm39) |
missense |
probably benign |
|
|
R1627:Nup210l
|
UTSW |
3 |
90,051,476 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1827:Nup210l
|
UTSW |
3 |
90,061,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1843:Nup210l
|
UTSW |
3 |
90,079,393 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1858:Nup210l
|
UTSW |
3 |
90,061,806 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1942:Nup210l
|
UTSW |
3 |
90,058,544 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2015:Nup210l
|
UTSW |
3 |
90,092,739 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2113:Nup210l
|
UTSW |
3 |
90,098,281 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R2944:Nup210l
|
UTSW |
3 |
90,088,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3736:Nup210l
|
UTSW |
3 |
90,027,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3740:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3741:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3742:Nup210l
|
UTSW |
3 |
90,114,701 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3771:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3773:Nup210l
|
UTSW |
3 |
90,027,201 (GRCm39) |
nonsense |
probably null |
|
|
R3879:Nup210l
|
UTSW |
3 |
90,092,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3882:Nup210l
|
UTSW |
3 |
90,031,517 (GRCm39) |
missense |
probably benign |
0.19 |
|
R3953:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3954:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3955:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3956:Nup210l
|
UTSW |
3 |
90,100,361 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4200:Nup210l
|
UTSW |
3 |
90,027,218 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4290:Nup210l
|
UTSW |
3 |
90,114,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4328:Nup210l
|
UTSW |
3 |
90,083,142 (GRCm39) |
splice site |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,098,181 (GRCm39) |
nonsense |
probably null |
|
|
R4629:Nup210l
|
UTSW |
3 |
90,075,182 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4897:Nup210l
|
UTSW |
3 |
90,100,378 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4906:Nup210l
|
UTSW |
3 |
90,077,337 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4966:Nup210l
|
UTSW |
3 |
90,014,208 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5004:Nup210l
|
UTSW |
3 |
90,087,472 (GRCm39) |
nonsense |
probably null |
|
|
R5237:Nup210l
|
UTSW |
3 |
90,087,505 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5499:Nup210l
|
UTSW |
3 |
90,081,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5522:Nup210l
|
UTSW |
3 |
90,061,972 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5627:Nup210l
|
UTSW |
3 |
90,051,557 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R5678:Nup210l
|
UTSW |
3 |
90,098,266 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5726:Nup210l
|
UTSW |
3 |
90,036,514 (GRCm39) |
splice site |
probably null |
|
|
R5792:Nup210l
|
UTSW |
3 |
90,107,164 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6129:Nup210l
|
UTSW |
3 |
90,011,483 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6272:Nup210l
|
UTSW |
3 |
90,077,331 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6290:Nup210l
|
UTSW |
3 |
90,027,216 (GRCm39) |
nonsense |
probably null |
|
|
R6293:Nup210l
|
UTSW |
3 |
90,022,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6446:Nup210l
|
UTSW |
3 |
90,079,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6698:Nup210l
|
UTSW |
3 |
90,089,815 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R6855:Nup210l
|
UTSW |
3 |
90,044,231 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6895:Nup210l
|
UTSW |
3 |
90,067,231 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6899:Nup210l
|
UTSW |
3 |
90,075,204 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6978:Nup210l
|
UTSW |
3 |
90,061,873 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6980:Nup210l
|
UTSW |
3 |
90,027,234 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7038:Nup210l
|
UTSW |
3 |
90,067,254 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7273:Nup210l
|
UTSW |
3 |
90,025,854 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7450:Nup210l
|
UTSW |
3 |
90,022,495 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7514:Nup210l
|
UTSW |
3 |
90,117,766 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7658:Nup210l
|
UTSW |
3 |
90,119,300 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7735:Nup210l
|
UTSW |
3 |
90,092,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7772:Nup210l
|
UTSW |
3 |
90,067,233 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7800:Nup210l
|
UTSW |
3 |
90,041,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7840:Nup210l
|
UTSW |
3 |
90,030,036 (GRCm39) |
missense |
probably benign |
0.08 |
|
R7847:Nup210l
|
UTSW |
3 |
90,058,430 (GRCm39) |
missense |
probably benign |
|
|
R7848:Nup210l
|
UTSW |
3 |
90,111,212 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8084:Nup210l
|
UTSW |
3 |
90,043,365 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8121:Nup210l
|
UTSW |
3 |
90,022,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8421:Nup210l
|
UTSW |
3 |
90,111,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8458:Nup210l
|
UTSW |
3 |
90,092,874 (GRCm39) |
missense |
probably null |
1.00 |
|
R8701:Nup210l
|
UTSW |
3 |
90,030,121 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8720:Nup210l
|
UTSW |
3 |
90,117,681 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8770:Nup210l
|
UTSW |
3 |
90,025,850 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8896:Nup210l
|
UTSW |
3 |
90,025,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9033:Nup210l
|
UTSW |
3 |
90,105,396 (GRCm39) |
missense |
probably benign |
|
|
R9371:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9373:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9381:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9426:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9427:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9501:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9523:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9574:Nup210l
|
UTSW |
3 |
90,117,693 (GRCm39) |
missense |
probably benign |
|
|
R9612:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9654:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9660:Nup210l
|
UTSW |
3 |
90,105,402 (GRCm39) |
missense |
probably benign |
0.30 |
|
R9662:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9682:Nup210l
|
UTSW |
3 |
90,051,469 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R9729:Nup210l
|
UTSW |
3 |
90,107,173 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9750:Nup210l
|
UTSW |
3 |
90,117,659 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGAGCTGACATGCTCTCTGTGC -3'
(R):5'- TGCAAAGCTGTAGGCTAATCCCTTC -3'
Sequencing Primer
(F):5'- gtcctcttgcctcagcc -3'
(R):5'- ccacatgctaggcaaggac -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation