Incidental Mutation 'R1727:Plxnb1'
| ID |
198247 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Plxnb1
|
| Ensembl Gene |
ENSMUSG00000053646 |
| Gene Name |
plexin B1 |
| Synonyms |
2900002G15Rik |
| MMRRC Submission |
039759-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R1727 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
108924457-108948985 bp(+) (GRCm39) |
| Type of Mutation |
splice site (559 bp from exon) |
| DNA Base Change (assembly) |
A to G
at 108930125 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000115265
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000072093]
[ENSMUST00000130366]
[ENSMUST00000131462]
|
| AlphaFold |
Q8CJH3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000072093
AA Change: D327G
PolyPhen 2
Score 0.361 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000071966
Gene: ENSMUSG00000053646
AA Change: D327G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Sema
|
35 |
463 |
5.84e-101 |
SMART |
|
PSI
|
481 |
534 |
1.17e-13 |
SMART |
|
PSI
|
628 |
678 |
6.97e-3 |
SMART |
|
low complexity region
|
691 |
706 |
N/A |
INTRINSIC |
|
low complexity region
|
752 |
771 |
N/A |
INTRINSIC |
|
PSI
|
1019 |
1066 |
2.06e-5 |
SMART |
|
IPT
|
1067 |
1158 |
7.48e-18 |
SMART |
|
IPT
|
1159 |
1247 |
3.97e-22 |
SMART |
|
IPT
|
1249 |
1359 |
6.09e-9 |
SMART |
|
low complexity region
|
1483 |
1494 |
N/A |
INTRINSIC |
|
Pfam:Plexin_cytopl
|
1546 |
2086 |
6.5e-230 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000130366
|
| SMART Domains |
Protein: ENSMUSP00000114358
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000131462
|
| SMART Domains |
Protein: ENSMUSP00000115265
Gene: ENSMUSG00000053646
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
Pfam:Sema
|
35 |
138 |
7.5e-11 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134690
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000192117
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192988
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000195364
|
| Meta Mutation Damage Score |
0.1908 |
| Coding Region Coverage |
- 1x: 97.5%
- 3x: 96.9%
- 10x: 95.3%
- 20x: 92.3%
|
| Validation Efficiency |
96% (98/102) |
| MGI Phenotype |
PHENOTYPE: Homozygous null mutants are viable and fertile and show no apparent defects in development, adult histology or basic functional parameters. However, a transitory renal phenotype, characterized by increased ureteric branching and enlarged kidneys, is noted over early stages of renal development. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamts6 |
T |
C |
13: 104,565,472 (GRCm39) |
|
probably benign |
Het |
| Ak2 |
C |
T |
4: 128,901,556 (GRCm39) |
P159L |
probably damaging |
Het |
| Akap8l |
C |
T |
17: 32,551,457 (GRCm39) |
R511H |
probably damaging |
Het |
| Akr1a1 |
A |
G |
4: 116,498,248 (GRCm39) |
L99P |
probably damaging |
Het |
| Anxa8 |
T |
A |
14: 33,811,547 (GRCm39) |
M34K |
probably damaging |
Het |
| Axl |
T |
G |
7: 25,460,191 (GRCm39) |
D767A |
possibly damaging |
Het |
| B430305J03Rik |
A |
G |
3: 61,271,299 (GRCm39) |
|
probably benign |
Het |
| Cdh24 |
A |
T |
14: 54,876,095 (GRCm39) |
Y182* |
probably null |
Het |
| Cdk5rap2 |
T |
C |
4: 70,190,916 (GRCm39) |
D1043G |
probably benign |
Het |
| Cdk5rap2 |
A |
T |
4: 70,208,209 (GRCm39) |
S746T |
possibly damaging |
Het |
| Cep120 |
T |
C |
18: 53,860,801 (GRCm39) |
M210V |
probably benign |
Het |
| Chga |
C |
T |
12: 102,527,696 (GRCm39) |
H117Y |
possibly damaging |
Het |
| Cnga4 |
T |
C |
7: 105,054,961 (GRCm39) |
W79R |
probably damaging |
Het |
| Cntnap5b |
C |
T |
1: 100,141,469 (GRCm39) |
T575I |
possibly damaging |
Het |
| Col6a3 |
T |
A |
1: 90,724,296 (GRCm39) |
|
probably null |
Het |
| Copz2 |
T |
C |
11: 96,744,301 (GRCm39) |
V71A |
probably benign |
Het |
| Dennd3 |
G |
T |
15: 73,436,977 (GRCm39) |
R1068L |
possibly damaging |
Het |
| Dhrs7 |
T |
C |
12: 72,706,238 (GRCm39) |
T56A |
probably damaging |
Het |
| Dnah17 |
G |
A |
11: 117,961,315 (GRCm39) |
T2557I |
probably damaging |
Het |
| Dnah17 |
A |
T |
11: 117,987,362 (GRCm39) |
L1320* |
probably null |
Het |
| Dynlt2b |
T |
A |
16: 32,241,751 (GRCm39) |
M78K |
probably benign |
Het |
| Eif3b |
T |
C |
5: 140,411,077 (GRCm39) |
I176T |
probably damaging |
Het |
| Eif4b |
T |
A |
15: 101,998,497 (GRCm39) |
D392E |
possibly damaging |
Het |
| Eif4h |
T |
C |
5: 134,668,134 (GRCm39) |
Y7C |
probably damaging |
Het |
| Enam |
A |
T |
5: 88,651,853 (GRCm39) |
S1046C |
probably damaging |
Het |
| Epg5 |
T |
A |
18: 78,059,030 (GRCm39) |
V1928E |
possibly damaging |
Het |
| Erbin |
T |
A |
13: 103,964,476 (GRCm39) |
E1222V |
probably benign |
Het |
| Fhdc1 |
T |
A |
3: 84,353,483 (GRCm39) |
I581F |
possibly damaging |
Het |
| Fhip2b |
C |
A |
14: 70,831,438 (GRCm39) |
G32V |
probably damaging |
Het |
| Fstl4 |
A |
C |
11: 52,959,478 (GRCm39) |
Q173P |
probably damaging |
Het |
| Gm266 |
A |
G |
12: 111,451,913 (GRCm39) |
F98L |
possibly damaging |
Het |
| Gsdmc2 |
T |
C |
15: 63,721,628 (GRCm39) |
|
probably benign |
Het |
| Gtf2h3 |
A |
G |
5: 124,728,419 (GRCm39) |
Q156R |
probably benign |
Het |
| H2-T23 |
T |
C |
17: 36,342,545 (GRCm39) |
T198A |
possibly damaging |
Het |
| Il1r1 |
C |
A |
1: 40,332,424 (GRCm39) |
A68E |
probably benign |
Het |
| Kcna7 |
A |
T |
7: 45,058,930 (GRCm39) |
I406F |
possibly damaging |
Het |
| Lbr |
A |
G |
1: 181,647,481 (GRCm39) |
I432T |
probably benign |
Het |
| Lnx1 |
A |
T |
5: 74,768,577 (GRCm39) |
|
probably null |
Het |
| Lrrcc1 |
T |
A |
3: 14,602,423 (GRCm39) |
I50N |
probably damaging |
Het |
| Lss |
T |
C |
10: 76,375,678 (GRCm39) |
V237A |
possibly damaging |
Het |
| Mcm10 |
A |
G |
2: 5,011,336 (GRCm39) |
F212L |
probably benign |
Het |
| Methig1 |
A |
C |
15: 100,251,130 (GRCm39) |
I14L |
probably benign |
Het |
| Mrpl41 |
A |
T |
2: 24,864,636 (GRCm39) |
V55E |
probably damaging |
Het |
| Mtfp1 |
C |
A |
11: 4,043,982 (GRCm39) |
D83Y |
probably damaging |
Het |
| Myh1 |
T |
A |
11: 67,101,292 (GRCm39) |
|
probably benign |
Het |
| Myo1e |
T |
C |
9: 70,283,806 (GRCm39) |
F834S |
possibly damaging |
Het |
| Ndufs7 |
A |
T |
10: 80,091,853 (GRCm39) |
|
probably benign |
Het |
| Nlrp4e |
T |
A |
7: 23,020,420 (GRCm39) |
N302K |
probably benign |
Het |
| Nt5e |
T |
A |
9: 88,210,082 (GRCm39) |
M115K |
possibly damaging |
Het |
| Nup153 |
A |
T |
13: 46,847,261 (GRCm39) |
C723S |
probably damaging |
Het |
| Obox6 |
G |
A |
7: 15,568,502 (GRCm39) |
P125S |
probably benign |
Het |
| Or1n2 |
G |
A |
2: 36,797,405 (GRCm39) |
C149Y |
probably benign |
Het |
| Or2t48 |
A |
T |
11: 58,420,342 (GRCm39) |
S157T |
possibly damaging |
Het |
| Or52n3 |
C |
T |
7: 104,530,721 (GRCm39) |
T269I |
probably benign |
Het |
| Or5an11 |
T |
G |
19: 12,246,365 (GRCm39) |
I257S |
possibly damaging |
Het |
| Or8i2 |
A |
G |
2: 86,852,607 (GRCm39) |
F94L |
probably damaging |
Het |
| Pcdh1 |
A |
C |
18: 38,336,085 (GRCm39) |
Y44* |
probably null |
Het |
| Pcdhb6 |
A |
T |
18: 37,467,640 (GRCm39) |
D187V |
probably damaging |
Het |
| Pclo |
A |
G |
5: 14,727,001 (GRCm39) |
|
probably benign |
Het |
| Pdcl3 |
T |
A |
1: 39,034,836 (GRCm39) |
I80K |
possibly damaging |
Het |
| Pde12 |
A |
T |
14: 26,390,022 (GRCm39) |
V229E |
probably benign |
Het |
| Plcg1 |
A |
G |
2: 160,590,008 (GRCm39) |
E142G |
probably benign |
Het |
| Pnpla1 |
A |
G |
17: 29,097,508 (GRCm39) |
I225V |
probably benign |
Het |
| Polr2f |
A |
G |
15: 79,028,805 (GRCm39) |
|
probably benign |
Het |
| Prob1 |
A |
G |
18: 35,787,364 (GRCm39) |
S297P |
possibly damaging |
Het |
| Qsox2 |
A |
C |
2: 26,110,970 (GRCm39) |
S132A |
probably benign |
Het |
| Rab19 |
T |
A |
6: 39,365,095 (GRCm39) |
Y118* |
probably null |
Het |
| Rfwd3 |
C |
T |
8: 112,014,874 (GRCm39) |
R326Q |
probably damaging |
Het |
| Rptn |
T |
C |
3: 93,304,445 (GRCm39) |
S593P |
possibly damaging |
Het |
| Septin11 |
T |
C |
5: 93,304,783 (GRCm39) |
I200T |
probably damaging |
Het |
| Slc10a4 |
T |
A |
5: 73,173,491 (GRCm39) |
|
probably benign |
Het |
| Slc9c1 |
A |
T |
16: 45,422,324 (GRCm39) |
I1130F |
probably benign |
Het |
| Slit3 |
C |
T |
11: 35,520,659 (GRCm39) |
R599C |
probably damaging |
Het |
| Snx19 |
C |
T |
9: 30,344,662 (GRCm39) |
P622L |
probably damaging |
Het |
| Sspo |
T |
C |
6: 48,471,782 (GRCm39) |
L50P |
probably damaging |
Het |
| St8sia1 |
A |
T |
6: 142,822,453 (GRCm39) |
C137S |
probably damaging |
Het |
| Syt11 |
G |
C |
3: 88,669,259 (GRCm39) |
T211S |
possibly damaging |
Het |
| Tanc1 |
A |
C |
2: 59,621,153 (GRCm39) |
Y324S |
probably damaging |
Het |
| Tas2r136 |
T |
C |
6: 132,754,753 (GRCm39) |
I125V |
possibly damaging |
Het |
| Tbc1d15 |
A |
T |
10: 115,046,130 (GRCm39) |
W458R |
probably damaging |
Het |
| Tecta |
G |
T |
9: 42,270,597 (GRCm39) |
T1237N |
probably damaging |
Het |
| Tet2 |
T |
A |
3: 133,193,051 (GRCm39) |
D461V |
probably damaging |
Het |
| Tmco3 |
G |
A |
8: 13,368,866 (GRCm39) |
V573M |
possibly damaging |
Het |
| Tmem212 |
A |
T |
3: 27,938,961 (GRCm39) |
M175K |
probably benign |
Het |
| Traf6 |
A |
G |
2: 101,527,084 (GRCm39) |
H278R |
probably benign |
Het |
| Trerf1 |
T |
A |
17: 47,652,092 (GRCm39) |
|
noncoding transcript |
Het |
| Ttn |
A |
C |
2: 76,576,988 (GRCm39) |
V24635G |
probably damaging |
Het |
| Ush1c |
A |
T |
7: 45,858,655 (GRCm39) |
D544E |
probably damaging |
Het |
| Usp47 |
C |
T |
7: 111,685,307 (GRCm39) |
T586M |
probably damaging |
Het |
| Vmn2r1 |
T |
A |
3: 63,989,163 (GRCm39) |
M34K |
probably benign |
Het |
| Vmn2r102 |
T |
A |
17: 19,897,770 (GRCm39) |
W262R |
probably damaging |
Het |
| Wasf3 |
C |
T |
5: 146,403,769 (GRCm39) |
A293V |
probably benign |
Het |
| Xrn2 |
A |
G |
2: 146,903,436 (GRCm39) |
Q812R |
probably benign |
Het |
| Zc3h7b |
T |
C |
15: 81,652,230 (GRCm39) |
I10T |
probably damaging |
Het |
| Zfp747 |
A |
T |
7: 126,973,249 (GRCm39) |
L307Q |
probably damaging |
Het |
| Zfp777 |
A |
T |
6: 48,020,824 (GRCm39) |
F266Y |
probably damaging |
Het |
|
| Other mutations in Plxnb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00593:Plxnb1
|
APN |
9 |
108,942,936 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01014:Plxnb1
|
APN |
9 |
108,935,102 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01142:Plxnb1
|
APN |
9 |
108,931,765 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01454:Plxnb1
|
APN |
9 |
108,942,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01469:Plxnb1
|
APN |
9 |
108,934,483 (GRCm39) |
intron |
probably benign |
|
|
IGL01530:Plxnb1
|
APN |
9 |
108,939,473 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01599:Plxnb1
|
APN |
9 |
108,939,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01968:Plxnb1
|
APN |
9 |
108,930,052 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02175:Plxnb1
|
APN |
9 |
108,929,914 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02216:Plxnb1
|
APN |
9 |
108,929,918 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02277:Plxnb1
|
APN |
9 |
108,941,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02311:Plxnb1
|
APN |
9 |
108,930,190 (GRCm39) |
missense |
probably benign |
|
|
IGL02645:Plxnb1
|
APN |
9 |
108,943,311 (GRCm39) |
splice site |
probably benign |
|
|
IGL03076:Plxnb1
|
APN |
9 |
108,935,970 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03107:Plxnb1
|
APN |
9 |
108,934,054 (GRCm39) |
missense |
probably benign |
|
|
IGL03343:Plxnb1
|
APN |
9 |
108,943,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4431001:Plxnb1
|
UTSW |
9 |
108,929,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0117:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0211:Plxnb1
|
UTSW |
9 |
108,932,731 (GRCm39) |
nonsense |
probably null |
|
|
R0843:Plxnb1
|
UTSW |
9 |
108,942,769 (GRCm39) |
missense |
probably benign |
0.20 |
|
R0970:Plxnb1
|
UTSW |
9 |
108,932,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Plxnb1
|
UTSW |
9 |
108,931,210 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R1342:Plxnb1
|
UTSW |
9 |
108,929,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R1386:Plxnb1
|
UTSW |
9 |
108,930,091 (GRCm39) |
missense |
probably benign |
0.27 |
|
R1419:Plxnb1
|
UTSW |
9 |
108,943,454 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1445:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
probably null |
|
|
R1548:Plxnb1
|
UTSW |
9 |
108,929,968 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1621:Plxnb1
|
UTSW |
9 |
108,935,873 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1658:Plxnb1
|
UTSW |
9 |
108,931,939 (GRCm39) |
nonsense |
probably null |
|
|
R1750:Plxnb1
|
UTSW |
9 |
108,940,836 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1795:Plxnb1
|
UTSW |
9 |
108,929,813 (GRCm39) |
missense |
probably benign |
|
|
R1929:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R1935:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1936:Plxnb1
|
UTSW |
9 |
108,924,715 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2014:Plxnb1
|
UTSW |
9 |
108,935,687 (GRCm39) |
splice site |
probably benign |
|
|
R2057:Plxnb1
|
UTSW |
9 |
108,938,294 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R2102:Plxnb1
|
UTSW |
9 |
108,944,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2271:Plxnb1
|
UTSW |
9 |
108,931,776 (GRCm39) |
splice site |
probably null |
|
|
R2422:Plxnb1
|
UTSW |
9 |
108,937,506 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2881:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3409:Plxnb1
|
UTSW |
9 |
108,935,681 (GRCm39) |
splice site |
probably null |
|
|
R3417:Plxnb1
|
UTSW |
9 |
108,929,828 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R3756:Plxnb1
|
UTSW |
9 |
108,942,526 (GRCm39) |
unclassified |
probably benign |
|
|
R3788:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R3789:Plxnb1
|
UTSW |
9 |
108,938,355 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4042:Plxnb1
|
UTSW |
9 |
108,934,241 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4289:Plxnb1
|
UTSW |
9 |
108,943,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4396:Plxnb1
|
UTSW |
9 |
108,929,291 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R4564:Plxnb1
|
UTSW |
9 |
108,942,488 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4676:Plxnb1
|
UTSW |
9 |
108,939,503 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4706:Plxnb1
|
UTSW |
9 |
108,941,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4792:Plxnb1
|
UTSW |
9 |
108,939,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4796:Plxnb1
|
UTSW |
9 |
108,943,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4835:Plxnb1
|
UTSW |
9 |
108,934,442 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4901:Plxnb1
|
UTSW |
9 |
108,934,027 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4952:Plxnb1
|
UTSW |
9 |
108,943,904 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5005:Plxnb1
|
UTSW |
9 |
108,935,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5015:Plxnb1
|
UTSW |
9 |
108,929,498 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5029:Plxnb1
|
UTSW |
9 |
108,943,723 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5180:Plxnb1
|
UTSW |
9 |
108,940,761 (GRCm39) |
splice site |
probably null |
|
|
R5256:Plxnb1
|
UTSW |
9 |
108,943,661 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5285:Plxnb1
|
UTSW |
9 |
108,937,527 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5431:Plxnb1
|
UTSW |
9 |
108,929,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5444:Plxnb1
|
UTSW |
9 |
108,935,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R5546:Plxnb1
|
UTSW |
9 |
108,929,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5852:Plxnb1
|
UTSW |
9 |
108,935,518 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5892:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6020:Plxnb1
|
UTSW |
9 |
108,945,679 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6053:Plxnb1
|
UTSW |
9 |
108,940,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6177:Plxnb1
|
UTSW |
9 |
108,931,993 (GRCm39) |
splice site |
probably null |
|
|
R6193:Plxnb1
|
UTSW |
9 |
108,933,971 (GRCm39) |
missense |
probably benign |
|
|
R6274:Plxnb1
|
UTSW |
9 |
108,941,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6310:Plxnb1
|
UTSW |
9 |
108,938,796 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6404:Plxnb1
|
UTSW |
9 |
108,945,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6422:Plxnb1
|
UTSW |
9 |
108,937,992 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6479:Plxnb1
|
UTSW |
9 |
108,940,733 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6555:Plxnb1
|
UTSW |
9 |
108,937,473 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6646:Plxnb1
|
UTSW |
9 |
108,937,895 (GRCm39) |
missense |
probably benign |
|
|
R6648:Plxnb1
|
UTSW |
9 |
108,933,398 (GRCm39) |
missense |
probably benign |
0.14 |
|
R6661:Plxnb1
|
UTSW |
9 |
108,933,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6674:Plxnb1
|
UTSW |
9 |
108,937,214 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6734:Plxnb1
|
UTSW |
9 |
108,937,988 (GRCm39) |
nonsense |
probably null |
|
|
R6859:Plxnb1
|
UTSW |
9 |
108,935,838 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6948:Plxnb1
|
UTSW |
9 |
108,945,702 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7030:Plxnb1
|
UTSW |
9 |
108,941,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7038:Plxnb1
|
UTSW |
9 |
108,929,453 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Plxnb1
|
UTSW |
9 |
108,929,243 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7427:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7428:Plxnb1
|
UTSW |
9 |
108,937,236 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7443:Plxnb1
|
UTSW |
9 |
108,943,675 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7527:Plxnb1
|
UTSW |
9 |
108,929,929 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7645:Plxnb1
|
UTSW |
9 |
108,943,480 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7680:Plxnb1
|
UTSW |
9 |
108,929,571 (GRCm39) |
nonsense |
probably null |
|
|
R7866:Plxnb1
|
UTSW |
9 |
108,929,525 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7898:Plxnb1
|
UTSW |
9 |
108,943,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7905:Plxnb1
|
UTSW |
9 |
108,938,300 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8092:Plxnb1
|
UTSW |
9 |
108,929,573 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8150:Plxnb1
|
UTSW |
9 |
108,941,146 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8286:Plxnb1
|
UTSW |
9 |
108,935,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Plxnb1
|
UTSW |
9 |
108,938,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8987:Plxnb1
|
UTSW |
9 |
108,937,178 (GRCm39) |
splice site |
probably benign |
|
|
R9176:Plxnb1
|
UTSW |
9 |
108,941,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9231:Plxnb1
|
UTSW |
9 |
108,934,286 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R9698:Plxnb1
|
UTSW |
9 |
108,925,251 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Plxnb1
|
UTSW |
9 |
108,937,989 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTATGTGGAATTGCCCCTGGCCTG -3'
(R):5'- AGAAGCACCTAACACCTGTCCTGAG -3'
Sequencing Primer
(F):5'- CTGCCAGGGTGGTCGTTAC -3'
(R):5'- TGTCCTGAGAGCCACCCTAC -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation