Incidental Mutation 'R1728:Dnah11'
| ID |
198604 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnah11
|
| Ensembl Gene |
ENSMUSG00000018581 |
| Gene Name |
dynein, axonemal, heavy chain 11 |
| Synonyms |
b2b598Clo, b2b1289Clo, b2b1203Clo, Dnahc11, avc4, b2b1279Clo, b2b1727Clo, lrd |
| MMRRC Submission |
039760-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.603)
|
| Stock # |
R1728 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
12 |
| Chromosomal Location |
117841717-118162778 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 117880666 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Valine
at position 3818
(D3818V)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000081867
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000084806]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000084806
AA Change: D3818V
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000081867
Gene: ENSMUSG00000018581
AA Change: D3818V
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
Pfam:DHC_N1
|
218 |
794 |
1.6e-162 |
PFAM |
|
low complexity region
|
1266 |
1282 |
N/A |
INTRINSIC |
|
Pfam:DHC_N2
|
1297 |
1705 |
1e-130 |
PFAM |
|
low complexity region
|
1757 |
1773 |
N/A |
INTRINSIC |
|
AAA
|
1869 |
1963 |
1.51e0 |
SMART |
|
Pfam:AAA_5
|
2150 |
2286 |
1.6e-12 |
PFAM |
|
AAA
|
2474 |
2619 |
1.48e-1 |
SMART |
|
AAA
|
2819 |
2931 |
4.57e-1 |
SMART |
|
Pfam:MT
|
3069 |
3413 |
3.2e-162 |
PFAM |
|
Pfam:AAA_9
|
3434 |
3656 |
2.9e-88 |
PFAM |
|
Pfam:Dynein_heavy
|
3790 |
4486 |
7.1e-235 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175662
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000176239
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000176756
|
| Coding Region Coverage |
- 1x: 97.4%
- 3x: 96.8%
- 10x: 95.0%
- 20x: 91.4%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a ciliary outer dynein arm protein and is a member of the dynein heavy chain family. It is a microtubule-dependent motor ATPase and has been reported to be involved in the movement of respiratory cilia. Mutations in this gene have been implicated in causing Kartagener Syndrome (a combination of situs inversus totalis and Primary Ciliary Dyskinesia (PCD), also called Immotile Cilia Syndrome 1 (ICS1)) and male sterility. [provided by RefSeq, Mar 2013]
PHENOTYPE: Approximately half of live-born homozygous mutants show situs inversus indicating that this gene is no longer properly controlling left-right asymmetry. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 223 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930447A16Rik |
G |
A |
15: 37,439,844 (GRCm39) |
|
probably benign |
Het |
| Aadat |
A |
G |
8: 60,979,746 (GRCm39) |
T203A |
probably damaging |
Het |
| Abca13 |
T |
A |
11: 9,199,680 (GRCm39) |
F104L |
probably benign |
Het |
| Acox1 |
T |
A |
11: 116,089,109 (GRCm39) |
|
probably null |
Het |
| Adam34l |
T |
C |
8: 44,078,620 (GRCm39) |
N535D |
probably damaging |
Het |
| Adamts17 |
C |
T |
7: 66,799,704 (GRCm39) |
R1060* |
probably null |
Het |
| Adgrg6 |
T |
C |
10: 14,315,526 (GRCm39) |
T593A |
probably damaging |
Het |
| Ankrd12 |
G |
T |
17: 66,291,071 (GRCm39) |
P1454Q |
probably benign |
Het |
| Ap2m1 |
T |
A |
16: 20,358,088 (GRCm39) |
N35K |
probably damaging |
Het |
| Aspm |
A |
G |
1: 139,401,312 (GRCm39) |
I1111V |
probably benign |
Het |
| Atr |
G |
A |
9: 95,779,634 (GRCm39) |
V1331I |
probably benign |
Het |
| Bola1 |
C |
T |
3: 96,104,426 (GRCm39) |
G56D |
probably benign |
Het |
| Brsk1 |
A |
G |
7: 4,707,218 (GRCm39) |
D257G |
probably damaging |
Het |
| C4bp |
C |
G |
1: 130,570,725 (GRCm39) |
V284L |
probably benign |
Het |
| Cacna1s |
T |
C |
1: 136,046,454 (GRCm39) |
F1761S |
probably benign |
Het |
| Camsap2 |
C |
T |
1: 136,209,053 (GRCm39) |
R802Q |
probably benign |
Het |
| Cbs |
G |
T |
17: 31,839,923 (GRCm39) |
A337E |
probably benign |
Het |
| Ccdc186 |
A |
C |
19: 56,797,652 (GRCm39) |
H306Q |
probably benign |
Het |
| Ccdc93 |
T |
C |
1: 121,389,668 (GRCm39) |
V237A |
probably benign |
Het |
| Ccdc93 |
C |
T |
1: 121,383,855 (GRCm39) |
P192L |
probably benign |
Het |
| Cd55 |
C |
T |
1: 130,377,160 (GRCm39) |
V333I |
probably benign |
Het |
| Cd55 |
C |
A |
1: 130,387,370 (GRCm39) |
A143S |
probably benign |
Het |
| Cdh19 |
C |
A |
1: 110,821,114 (GRCm39) |
E541D |
probably damaging |
Het |
| Cdh20 |
C |
G |
1: 109,993,465 (GRCm39) |
L307V |
possibly damaging |
Het |
| Cfh |
C |
T |
1: 140,075,435 (GRCm39) |
V268I |
possibly damaging |
Het |
| Cfhr2 |
A |
G |
1: 139,741,180 (GRCm39) |
M265T |
probably benign |
Het |
| Cfhr2 |
A |
C |
1: 139,741,197 (GRCm39) |
N259K |
probably benign |
Het |
| Chi3l1 |
C |
T |
1: 134,116,267 (GRCm39) |
A250V |
probably damaging |
Het |
| Chrnb1 |
C |
A |
11: 69,676,588 (GRCm39) |
D388Y |
probably damaging |
Het |
| Clcn1 |
T |
A |
6: 42,276,448 (GRCm39) |
F360Y |
possibly damaging |
Het |
| Clgn |
A |
G |
8: 84,149,659 (GRCm39) |
S387G |
probably damaging |
Het |
| Cntnap5a |
C |
T |
1: 116,382,873 (GRCm39) |
T1047I |
probably benign |
Het |
| Cntnap5a |
C |
A |
1: 116,382,734 (GRCm39) |
L1001I |
probably benign |
Het |
| Cntnap5a |
T |
C |
1: 116,382,831 (GRCm39) |
L1033S |
probably benign |
Het |
| Coil |
G |
A |
11: 88,864,802 (GRCm39) |
V10I |
probably damaging |
Het |
| Col4a1 |
G |
A |
8: 11,262,712 (GRCm39) |
P1256S |
possibly damaging |
Het |
| Copa |
T |
A |
1: 171,939,554 (GRCm39) |
F597Y |
probably benign |
Het |
| Crb1 |
G |
A |
1: 139,168,876 (GRCm39) |
P881S |
probably damaging |
Het |
| Crb1 |
C |
T |
1: 139,170,733 (GRCm39) |
G825R |
probably damaging |
Het |
| Crb1 |
C |
T |
1: 139,171,155 (GRCm39) |
R684H |
probably benign |
Het |
| Crb1 |
T |
C |
1: 139,162,517 (GRCm39) |
M1214V |
probably benign |
Het |
| Crb1 |
A |
T |
1: 139,165,360 (GRCm39) |
H921Q |
probably benign |
Het |
| Crybg1 |
T |
A |
10: 43,880,015 (GRCm39) |
Q391L |
probably damaging |
Het |
| Cspg4 |
G |
T |
9: 56,805,821 (GRCm39) |
V2211L |
probably benign |
Het |
| Cxcr4 |
C |
T |
1: 128,517,014 (GRCm39) |
V216I |
probably benign |
Het |
| Cyb5r1 |
C |
T |
1: 134,335,405 (GRCm39) |
R147W |
probably damaging |
Het |
| Ddx59 |
T |
C |
1: 136,344,791 (GRCm39) |
V154A |
probably benign |
Het |
| Dhx30 |
T |
C |
9: 109,927,819 (GRCm39) |
H101R |
probably damaging |
Het |
| Dnah17 |
C |
T |
11: 117,960,345 (GRCm39) |
C2572Y |
possibly damaging |
Het |
| Dsel |
T |
C |
1: 111,787,187 (GRCm39) |
N1116S |
probably benign |
Het |
| Dsel |
G |
C |
1: 111,787,724 (GRCm39) |
T937S |
probably benign |
Het |
| Dstyk |
C |
T |
1: 132,384,722 (GRCm39) |
L739F |
probably damaging |
Het |
| Ehf |
T |
G |
2: 103,104,251 (GRCm39) |
T186P |
possibly damaging |
Het |
| En1 |
A |
G |
1: 120,531,350 (GRCm39) |
S197G |
unknown |
Het |
| Etnk2 |
G |
T |
1: 133,293,503 (GRCm39) |
G149W |
probably damaging |
Het |
| Etnk2 |
C |
T |
1: 133,293,554 (GRCm39) |
R166* |
probably null |
Het |
| Etnk2 |
G |
A |
1: 133,293,555 (GRCm39) |
R166Q |
probably benign |
Het |
| Etnk2 |
T |
A |
1: 133,304,653 (GRCm39) |
V292E |
probably benign |
Het |
| Etnk2 |
C |
A |
1: 133,293,325 (GRCm39) |
D89E |
probably benign |
Het |
| Fam187b |
C |
T |
7: 30,688,445 (GRCm39) |
Q268* |
probably null |
Het |
| Fam72a |
C |
T |
1: 131,466,633 (GRCm39) |
T139M |
probably benign |
Het |
| Fam72a |
T |
C |
1: 131,458,406 (GRCm39) |
I56T |
probably benign |
Het |
| Fat3 |
A |
C |
9: 15,907,611 (GRCm39) |
V2797G |
possibly damaging |
Het |
| Fcamr |
A |
C |
1: 130,732,364 (GRCm39) |
N117T |
probably benign |
Het |
| Fcamr |
A |
G |
1: 130,739,317 (GRCm39) |
I206V |
probably benign |
Het |
| Fcamr |
G |
A |
1: 130,740,366 (GRCm39) |
G262S |
probably benign |
Het |
| Fcamr |
A |
G |
1: 130,740,429 (GRCm39) |
I283V |
probably benign |
Het |
| Fcamr |
T |
C |
1: 130,740,475 (GRCm39) |
V298A |
probably benign |
Het |
| Fcamr |
A |
G |
1: 130,740,546 (GRCm39) |
M322V |
probably benign |
Het |
| Fcamr |
C |
T |
1: 130,740,553 (GRCm39) |
P324L |
probably benign |
Het |
| Fcamr |
A |
G |
1: 130,742,334 (GRCm39) |
N574D |
probably benign |
Het |
| Fcamr |
A |
G |
1: 130,732,306 (GRCm39) |
R98G |
probably benign |
Het |
| Fcmr |
T |
C |
1: 130,806,006 (GRCm39) |
S321P |
probably benign |
Het |
| Fcmr |
A |
G |
1: 130,803,711 (GRCm39) |
T172A |
probably benign |
Het |
| Fut10 |
T |
A |
8: 31,691,418 (GRCm39) |
S88T |
probably benign |
Het |
| Gabarap |
C |
T |
11: 69,882,515 (GRCm39) |
|
probably benign |
Het |
| Gli2 |
G |
T |
1: 118,929,774 (GRCm39) |
H44Q |
probably benign |
Het |
| Gli2 |
C |
T |
1: 118,795,817 (GRCm39) |
A113T |
possibly damaging |
Het |
| Glrx2 |
C |
T |
1: 143,615,478 (GRCm39) |
A27V |
possibly damaging |
Het |
| Gm28040 |
AGTG |
AGTGGCACCTTTGGTG |
1: 133,255,059 (GRCm39) |
|
probably benign |
Het |
| Gpr25 |
G |
A |
1: 136,188,448 (GRCm39) |
P55L |
probably benign |
Het |
| Gse1 |
G |
A |
8: 121,294,992 (GRCm39) |
|
probably benign |
Het |
| Heatr4 |
T |
C |
12: 84,014,346 (GRCm39) |
I630M |
probably benign |
Het |
| Hectd4 |
A |
T |
5: 121,439,902 (GRCm39) |
Y1134F |
possibly damaging |
Het |
| Igfn1 |
G |
A |
1: 135,887,666 (GRCm39) |
P2466L |
probably damaging |
Het |
| Igfn1 |
C |
T |
1: 135,899,865 (GRCm39) |
R482Q |
probably benign |
Het |
| Igfn1 |
T |
C |
1: 135,898,149 (GRCm39) |
S806G |
probably benign |
Het |
| Igfn1 |
G |
A |
1: 135,895,937 (GRCm39) |
A1543V |
probably benign |
Het |
| Igfn1 |
C |
T |
1: 135,907,653 (GRCm39) |
A231T |
probably benign |
Het |
| Igfn1 |
G |
A |
1: 135,910,213 (GRCm39) |
R124W |
probably benign |
Het |
| Igfn1 |
T |
C |
1: 135,926,363 (GRCm39) |
E29G |
probably benign |
Het |
| Igfn1 |
T |
C |
1: 135,926,421 (GRCm39) |
I10V |
unknown |
Het |
| Ikbke |
T |
C |
1: 131,197,560 (GRCm39) |
S447G |
probably benign |
Het |
| Ikbke |
C |
A |
1: 131,193,674 (GRCm39) |
A459S |
probably benign |
Het |
| Ildr1 |
A |
T |
16: 36,528,698 (GRCm39) |
T48S |
possibly damaging |
Het |
| Ipo9 |
ATCCTCCTCCTCCTCCTC |
ATCCTCCTCCTCCTCCTCCTC |
1: 135,314,006 (GRCm39) |
|
probably benign |
Het |
| Ipo9 |
A |
G |
1: 135,329,988 (GRCm39) |
V484A |
probably benign |
Het |
| Ipo9 |
CTC |
CTCTTC |
1: 135,314,009 (GRCm39) |
|
probably benign |
Het |
| Itprid1 |
T |
C |
6: 55,945,526 (GRCm39) |
F749S |
probably benign |
Het |
| Jarid2 |
T |
A |
13: 45,059,752 (GRCm39) |
N661K |
probably damaging |
Het |
| Kcnh5 |
T |
C |
12: 75,184,465 (GRCm39) |
D86G |
probably benign |
Het |
| Kcnt2 |
G |
A |
1: 140,282,285 (GRCm39) |
S90N |
probably benign |
Het |
| Kif14 |
A |
G |
1: 136,396,713 (GRCm39) |
K340E |
probably damaging |
Het |
| Kif14 |
G |
A |
1: 136,406,103 (GRCm39) |
A556T |
probably benign |
Het |
| Kif14 |
A |
G |
1: 136,418,070 (GRCm39) |
S868G |
probably benign |
Het |
| Kif14 |
C |
T |
1: 136,431,169 (GRCm39) |
L1189F |
probably benign |
Het |
| Kif14 |
T |
C |
1: 136,443,699 (GRCm39) |
F1291L |
probably benign |
Het |
| Kif14 |
T |
C |
1: 136,453,521 (GRCm39) |
V1433A |
probably benign |
Het |
| Kif14 |
A |
G |
1: 136,396,017 (GRCm39) |
N108D |
probably benign |
Het |
| Kif1b |
T |
C |
4: 149,272,179 (GRCm39) |
T1541A |
probably damaging |
Het |
| Kif21b |
A |
G |
1: 136,087,859 (GRCm39) |
I983V |
possibly damaging |
Het |
| Kif26a |
T |
C |
12: 112,143,219 (GRCm39) |
S1158P |
possibly damaging |
Het |
| Kmt2d |
A |
G |
15: 98,763,013 (GRCm39) |
C279R |
probably damaging |
Het |
| Kpna3 |
T |
A |
14: 61,605,150 (GRCm39) |
E499V |
probably benign |
Het |
| Krt16 |
T |
C |
11: 100,138,533 (GRCm39) |
E205G |
probably damaging |
Het |
| Lad1 |
C |
T |
1: 135,755,761 (GRCm39) |
R346C |
probably damaging |
Het |
| Lad1 |
C |
T |
1: 135,755,119 (GRCm39) |
P132S |
possibly damaging |
Het |
| Lax1 |
T |
C |
1: 133,608,307 (GRCm39) |
N145D |
probably benign |
Het |
| Lax1 |
G |
A |
1: 133,611,372 (GRCm39) |
P67S |
probably damaging |
Het |
| Lax1 |
T |
C |
1: 133,607,716 (GRCm39) |
R342G |
probably benign |
Het |
| Lgr6 |
C |
T |
1: 134,914,826 (GRCm39) |
V641I |
probably benign |
Het |
| Lgr6 |
G |
T |
1: 134,918,373 (GRCm39) |
H263N |
probably benign |
Het |
| Lgr6 |
C |
T |
1: 134,931,214 (GRCm39) |
S3N |
probably benign |
Het |
| Lmod1 |
C |
T |
1: 135,291,811 (GRCm39) |
T222I |
probably benign |
Het |
| Mb21d2 |
A |
G |
16: 28,647,173 (GRCm39) |
V267A |
probably benign |
Het |
| Mfrp |
A |
G |
9: 44,015,884 (GRCm39) |
T334A |
possibly damaging |
Het |
| Morc1 |
T |
A |
16: 48,432,660 (GRCm39) |
D709E |
probably benign |
Het |
| Mrgpra2b |
A |
G |
7: 47,114,627 (GRCm39) |
I35T |
probably benign |
Het |
| Mroh3 |
G |
C |
1: 136,119,882 (GRCm39) |
Q440E |
possibly damaging |
Het |
| Mybph |
C |
T |
1: 134,125,218 (GRCm39) |
R249C |
probably benign |
Het |
| Mycbp2 |
A |
T |
14: 103,392,614 (GRCm39) |
C3206S |
probably damaging |
Het |
| Nav1 |
A |
T |
1: 135,512,465 (GRCm39) |
D198E |
possibly damaging |
Het |
| Ndufaf7 |
A |
T |
17: 79,245,058 (GRCm39) |
K59M |
probably damaging |
Het |
| Necab3 |
T |
C |
2: 154,388,795 (GRCm39) |
S208G |
probably benign |
Het |
| Nr5a2 |
C |
A |
1: 136,879,863 (GRCm39) |
R35L |
probably benign |
Het |
| Obsl1 |
G |
A |
1: 75,486,756 (GRCm38) |
T1764M |
probably benign |
Het |
| Optc |
A |
T |
1: 133,831,534 (GRCm39) |
|
probably null |
Het |
| Optc |
C |
G |
1: 133,832,908 (GRCm39) |
S64T |
probably benign |
Het |
| Or2f1 |
C |
A |
6: 42,721,069 (GRCm39) |
L33M |
possibly damaging |
Het |
| Or3a1c |
A |
G |
11: 74,046,802 (GRCm39) |
D274G |
probably damaging |
Het |
| Or4a68 |
C |
T |
2: 89,269,927 (GRCm39) |
R232H |
probably benign |
Het |
| Or5m13b |
T |
A |
2: 85,754,466 (GRCm39) |
L285I |
possibly damaging |
Het |
| Or8b12i |
A |
T |
9: 20,082,209 (GRCm39) |
Y219* |
probably null |
Het |
| Otoa |
T |
C |
7: 120,724,662 (GRCm39) |
V447A |
probably benign |
Het |
| Papss1 |
A |
G |
3: 131,311,728 (GRCm39) |
N319D |
probably benign |
Het |
| Patj |
G |
A |
4: 98,320,017 (GRCm39) |
G428D |
possibly damaging |
Het |
| Pcdhb3 |
G |
A |
18: 37,434,931 (GRCm39) |
G299D |
probably damaging |
Het |
| Pcsk4 |
T |
C |
10: 80,159,404 (GRCm39) |
D432G |
probably damaging |
Het |
| Pde5a |
G |
T |
3: 122,541,889 (GRCm39) |
L126F |
probably damaging |
Het |
| Pigr |
C |
T |
1: 130,772,259 (GRCm39) |
A159V |
possibly damaging |
Het |
| Pik3c2b |
C |
T |
1: 132,994,365 (GRCm39) |
P110S |
probably benign |
Het |
| Pinx1 |
A |
G |
14: 64,115,559 (GRCm39) |
|
probably null |
Het |
| Plec |
C |
A |
15: 76,061,892 (GRCm39) |
E2547* |
probably null |
Het |
| Plekha6 |
C |
G |
1: 133,215,584 (GRCm39) |
T792S |
probably benign |
Het |
| Ppfia4 |
G |
A |
1: 134,227,059 (GRCm39) |
P1159S |
probably benign |
Het |
| Prelp |
C |
T |
1: 133,842,869 (GRCm39) |
R92K |
probably benign |
Het |
| Prrx1 |
T |
A |
1: 163,089,536 (GRCm39) |
N97I |
probably damaging |
Het |
| Ptpn7 |
A |
G |
1: 135,062,213 (GRCm39) |
Q53R |
probably benign |
Het |
| Ptprc |
A |
G |
1: 138,035,575 (GRCm39) |
V400A |
probably benign |
Het |
| Ptprc |
C |
A |
1: 138,035,562 (GRCm39) |
E402D |
probably benign |
Het |
| Ptprc |
A |
G |
1: 138,035,561 (GRCm39) |
S405P |
probably benign |
Het |
| Ptprc |
T |
G |
1: 138,027,414 (GRCm39) |
N478T |
probably benign |
Het |
| Ptprc |
T |
C |
1: 138,039,992 (GRCm39) |
K212E |
possibly damaging |
Het |
| Rab29 |
A |
G |
1: 131,799,848 (GRCm39) |
Q141R |
probably benign |
Het |
| Rbsn |
A |
T |
6: 92,167,000 (GRCm39) |
L548Q |
possibly damaging |
Het |
| Ren1 |
C |
T |
1: 133,281,975 (GRCm39) |
T32I |
probably benign |
Het |
| Ren1 |
T |
A |
1: 133,281,944 (GRCm39) |
W22R |
probably damaging |
Het |
| Ren1 |
C |
G |
1: 133,287,745 (GRCm39) |
L360V |
probably benign |
Het |
| Ren1 |
A |
T |
1: 133,287,721 (GRCm39) |
N352Y |
probably benign |
Het |
| Ren1 |
A |
T |
1: 133,286,817 (GRCm39) |
E315D |
probably benign |
Het |
| Ren1 |
C |
A |
1: 133,286,720 (GRCm39) |
|
probably null |
Het |
| Ren1 |
A |
C |
1: 133,284,195 (GRCm39) |
K187Q |
probably benign |
Het |
| Rnpep |
C |
T |
1: 135,190,834 (GRCm39) |
A571T |
possibly damaging |
Het |
| Rnpep |
G |
C |
1: 135,211,715 (GRCm39) |
A11G |
probably benign |
Het |
| Ro60 |
T |
C |
1: 143,635,772 (GRCm39) |
D458G |
probably benign |
Het |
| Ro60 |
C |
T |
1: 143,635,752 (GRCm39) |
V465I |
probably benign |
Het |
| Ryr2 |
C |
T |
13: 11,602,308 (GRCm39) |
V4525M |
possibly damaging |
Het |
| Sctr |
G |
A |
1: 119,990,987 (GRCm39) |
S440N |
possibly damaging |
Het |
| Sctr |
T |
C |
1: 119,959,386 (GRCm39) |
F110L |
probably benign |
Het |
| Serpinb10 |
C |
T |
1: 107,466,203 (GRCm39) |
S63F |
probably damaging |
Het |
| Serpinb2 |
G |
A |
1: 107,443,365 (GRCm39) |
A55T |
probably damaging |
Het |
| Serpinb2 |
A |
C |
1: 107,452,273 (GRCm39) |
S284R |
probably benign |
Het |
| Serpinb2 |
C |
T |
1: 107,451,624 (GRCm39) |
T259I |
probably benign |
Het |
| Serpinb2 |
C |
T |
1: 107,451,620 (GRCm39) |
H258Y |
probably benign |
Het |
| Serpinb2 |
C |
A |
1: 107,451,564 (GRCm39) |
A239E |
probably benign |
Het |
| Serpinb8 |
A |
G |
1: 107,525,257 (GRCm39) |
S20G |
probably benign |
Het |
| Serpinb8 |
A |
C |
1: 107,534,734 (GRCm39) |
L268F |
probably benign |
Het |
| Serpinb8 |
G |
A |
1: 107,526,684 (GRCm39) |
A75T |
probably benign |
Het |
| Sis |
A |
T |
3: 72,872,978 (GRCm39) |
C53* |
probably null |
Het |
| Slc13a5 |
C |
T |
11: 72,157,285 (GRCm39) |
|
probably null |
Het |
| Slc26a9 |
C |
T |
1: 131,691,608 (GRCm39) |
A617V |
probably benign |
Het |
| Slc26a9 |
C |
A |
1: 131,693,750 (GRCm39) |
R747S |
probably benign |
Het |
| Slc9a8 |
T |
C |
2: 167,266,065 (GRCm39) |
F14S |
probably benign |
Het |
| Spock3 |
T |
C |
8: 63,802,011 (GRCm39) |
L330P |
probably damaging |
Het |
| Stab2 |
T |
G |
10: 86,773,903 (GRCm39) |
R809S |
probably benign |
Het |
| Steap3 |
T |
C |
1: 120,155,480 (GRCm39) |
N493S |
probably benign |
Het |
| Steap3 |
G |
A |
1: 120,162,108 (GRCm39) |
A350V |
probably benign |
Het |
| Tecta |
G |
A |
9: 42,303,218 (GRCm39) |
T138I |
probably benign |
Het |
| Thsd7b |
G |
C |
1: 129,605,920 (GRCm39) |
A554P |
probably benign |
Het |
| Thsd7b |
A |
C |
1: 130,044,368 (GRCm39) |
Q1116P |
probably benign |
Het |
| Thsd7b |
C |
T |
1: 129,556,628 (GRCm39) |
T328I |
probably damaging |
Het |
| Thsd7b |
T |
A |
1: 129,595,674 (GRCm39) |
F498Y |
probably benign |
Het |
| Tnnt2 |
C |
T |
1: 135,773,244 (GRCm39) |
|
probably benign |
Het |
| Traf7 |
A |
G |
17: 24,731,353 (GRCm39) |
F228L |
probably damaging |
Het |
| Trhr |
A |
G |
15: 44,060,549 (GRCm39) |
E23G |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,643,683 (GRCm39) |
G11436R |
probably damaging |
Het |
| Tubgcp2 |
T |
C |
7: 139,577,968 (GRCm39) |
T779A |
probably benign |
Het |
| Tusc2 |
A |
T |
9: 107,441,830 (GRCm39) |
I68F |
probably damaging |
Het |
| Ube2t |
C |
T |
1: 134,899,905 (GRCm39) |
A149V |
probably benign |
Het |
| Upf2 |
A |
T |
2: 6,032,261 (GRCm39) |
S191C |
probably damaging |
Het |
| Usp24 |
A |
G |
4: 106,217,618 (GRCm39) |
N447S |
possibly damaging |
Het |
| Usp42 |
T |
C |
5: 143,700,381 (GRCm39) |
D1214G |
probably damaging |
Het |
| Vcam1 |
T |
A |
3: 115,908,164 (GRCm39) |
I633L |
probably benign |
Het |
| Vmn2r73 |
T |
C |
7: 85,507,086 (GRCm39) |
Y742C |
probably damaging |
Het |
| Vmn2r81 |
C |
A |
10: 79,106,489 (GRCm39) |
T489K |
probably benign |
Het |
| Ypel1 |
C |
G |
16: 16,907,283 (GRCm39) |
|
probably benign |
Het |
| Zan |
C |
A |
5: 137,413,280 (GRCm39) |
|
probably benign |
Het |
| Zc3h11a |
C |
T |
1: 133,552,359 (GRCm39) |
V583I |
probably benign |
Het |
| Zc3h11a |
G |
A |
1: 133,549,892 (GRCm39) |
P695S |
probably benign |
Het |
| Zfp616 |
A |
C |
11: 73,976,597 (GRCm39) |
K955N |
probably damaging |
Het |
| Zfyve9 |
A |
C |
4: 108,575,698 (GRCm39) |
V461G |
possibly damaging |
Het |
| Zp3r |
A |
G |
1: 130,524,551 (GRCm39) |
L164P |
probably benign |
Het |
| Zp3r |
C |
A |
1: 130,547,151 (GRCm39) |
E8D |
possibly damaging |
Het |
|
| Other mutations in Dnah11 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00341:Dnah11
|
APN |
12 |
118,162,480 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL00422:Dnah11
|
APN |
12 |
118,031,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00436:Dnah11
|
APN |
12 |
118,000,194 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL00540:Dnah11
|
APN |
12 |
118,150,657 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00687:Dnah11
|
APN |
12 |
117,885,739 (GRCm39) |
splice site |
probably benign |
|
|
IGL00833:Dnah11
|
APN |
12 |
118,143,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00906:Dnah11
|
APN |
12 |
117,874,937 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00952:Dnah11
|
APN |
12 |
118,160,386 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL01111:Dnah11
|
APN |
12 |
118,106,669 (GRCm39) |
splice site |
probably benign |
|
|
IGL01121:Dnah11
|
APN |
12 |
118,014,430 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01143:Dnah11
|
APN |
12 |
117,976,475 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01359:Dnah11
|
APN |
12 |
117,946,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01372:Dnah11
|
APN |
12 |
118,156,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01410:Dnah11
|
APN |
12 |
118,010,991 (GRCm39) |
nonsense |
probably null |
|
|
IGL01418:Dnah11
|
APN |
12 |
117,951,217 (GRCm39) |
nonsense |
probably null |
|
|
IGL01444:Dnah11
|
APN |
12 |
117,983,967 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
IGL01606:Dnah11
|
APN |
12 |
117,946,767 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL01645:Dnah11
|
APN |
12 |
118,150,733 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01932:Dnah11
|
APN |
12 |
118,156,005 (GRCm39) |
splice site |
probably benign |
|
|
IGL02104:Dnah11
|
APN |
12 |
118,156,125 (GRCm39) |
missense |
probably benign |
|
|
IGL02151:Dnah11
|
APN |
12 |
118,023,623 (GRCm39) |
splice site |
probably benign |
|
|
IGL02189:Dnah11
|
APN |
12 |
118,046,314 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02417:Dnah11
|
APN |
12 |
118,020,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02421:Dnah11
|
APN |
12 |
118,150,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02444:Dnah11
|
APN |
12 |
117,939,608 (GRCm39) |
splice site |
probably benign |
|
|
IGL02474:Dnah11
|
APN |
12 |
117,991,180 (GRCm39) |
splice site |
probably null |
|
|
IGL02526:Dnah11
|
APN |
12 |
118,143,353 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL02887:Dnah11
|
APN |
12 |
117,874,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03011:Dnah11
|
APN |
12 |
117,976,112 (GRCm39) |
missense |
probably benign |
0.08 |
|
IGL03061:Dnah11
|
APN |
12 |
117,866,856 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03182:Dnah11
|
APN |
12 |
117,994,026 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03220:Dnah11
|
APN |
12 |
118,069,720 (GRCm39) |
missense |
probably benign |
|
|
IGL03238:Dnah11
|
APN |
12 |
118,073,633 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03493:Dnah11
|
APN |
12 |
117,976,533 (GRCm39) |
missense |
probably benign |
0.00 |
|
P0045:Dnah11
|
UTSW |
12 |
117,994,062 (GRCm39) |
missense |
probably benign |
|
|
R0009:Dnah11
|
UTSW |
12 |
118,009,257 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0066:Dnah11
|
UTSW |
12 |
118,090,621 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0172:Dnah11
|
UTSW |
12 |
117,951,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0206:Dnah11
|
UTSW |
12 |
118,007,509 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0206:Dnah11
|
UTSW |
12 |
118,007,509 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0208:Dnah11
|
UTSW |
12 |
118,007,509 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0230:Dnah11
|
UTSW |
12 |
117,946,791 (GRCm39) |
nonsense |
probably null |
|
|
R0270:Dnah11
|
UTSW |
12 |
118,004,748 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0311:Dnah11
|
UTSW |
12 |
118,090,868 (GRCm39) |
missense |
probably benign |
0.03 |
|
R0325:Dnah11
|
UTSW |
12 |
117,976,074 (GRCm39) |
missense |
probably benign |
|
|
R0370:Dnah11
|
UTSW |
12 |
117,958,962 (GRCm39) |
missense |
probably benign |
|
|
R0416:Dnah11
|
UTSW |
12 |
117,874,793 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0505:Dnah11
|
UTSW |
12 |
118,070,245 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0540:Dnah11
|
UTSW |
12 |
118,046,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0554:Dnah11
|
UTSW |
12 |
117,894,913 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0607:Dnah11
|
UTSW |
12 |
118,046,246 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0620:Dnah11
|
UTSW |
12 |
117,951,204 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0635:Dnah11
|
UTSW |
12 |
117,971,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0755:Dnah11
|
UTSW |
12 |
118,162,360 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0755:Dnah11
|
UTSW |
12 |
117,918,564 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0789:Dnah11
|
UTSW |
12 |
117,874,967 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0833:Dnah11
|
UTSW |
12 |
118,160,397 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0835:Dnah11
|
UTSW |
12 |
117,880,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0836:Dnah11
|
UTSW |
12 |
118,160,397 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0846:Dnah11
|
UTSW |
12 |
117,897,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0865:Dnah11
|
UTSW |
12 |
118,154,579 (GRCm39) |
nonsense |
probably null |
|
|
R0928:Dnah11
|
UTSW |
12 |
118,009,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0939:Dnah11
|
UTSW |
12 |
118,024,142 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1203:Dnah11
|
UTSW |
12 |
117,897,547 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1394:Dnah11
|
UTSW |
12 |
117,936,099 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1398:Dnah11
|
UTSW |
12 |
118,020,841 (GRCm39) |
nonsense |
probably null |
|
|
R1465:Dnah11
|
UTSW |
12 |
118,002,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1465:Dnah11
|
UTSW |
12 |
118,002,430 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1500:Dnah11
|
UTSW |
12 |
117,976,564 (GRCm39) |
splice site |
probably null |
|
|
R1535:Dnah11
|
UTSW |
12 |
117,982,465 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1539:Dnah11
|
UTSW |
12 |
117,894,991 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1554:Dnah11
|
UTSW |
12 |
118,046,234 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1574:Dnah11
|
UTSW |
12 |
118,024,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1574:Dnah11
|
UTSW |
12 |
118,024,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Dnah11
|
UTSW |
12 |
118,014,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1618:Dnah11
|
UTSW |
12 |
117,979,200 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1638:Dnah11
|
UTSW |
12 |
117,979,154 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1659:Dnah11
|
UTSW |
12 |
118,084,459 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1671:Dnah11
|
UTSW |
12 |
117,880,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1678:Dnah11
|
UTSW |
12 |
117,897,580 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1699:Dnah11
|
UTSW |
12 |
118,154,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1712:Dnah11
|
UTSW |
12 |
118,160,379 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1729:Dnah11
|
UTSW |
12 |
117,880,666 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1764:Dnah11
|
UTSW |
12 |
118,154,560 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1780:Dnah11
|
UTSW |
12 |
117,991,293 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1789:Dnah11
|
UTSW |
12 |
118,002,515 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1800:Dnah11
|
UTSW |
12 |
117,880,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1863:Dnah11
|
UTSW |
12 |
118,027,587 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1892:Dnah11
|
UTSW |
12 |
118,070,209 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1907:Dnah11
|
UTSW |
12 |
118,091,291 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1964:Dnah11
|
UTSW |
12 |
118,106,027 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1967:Dnah11
|
UTSW |
12 |
117,880,523 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1997:Dnah11
|
UTSW |
12 |
118,046,203 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R2086:Dnah11
|
UTSW |
12 |
118,077,606 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R2092:Dnah11
|
UTSW |
12 |
117,976,451 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R2108:Dnah11
|
UTSW |
12 |
117,984,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2140:Dnah11
|
UTSW |
12 |
117,972,545 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2261:Dnah11
|
UTSW |
12 |
117,930,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2261:Dnah11
|
UTSW |
12 |
117,843,760 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2262:Dnah11
|
UTSW |
12 |
117,930,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2262:Dnah11
|
UTSW |
12 |
117,843,760 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2263:Dnah11
|
UTSW |
12 |
117,930,374 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2263:Dnah11
|
UTSW |
12 |
117,843,760 (GRCm39) |
missense |
probably benign |
0.06 |
|
R2328:Dnah11
|
UTSW |
12 |
117,850,421 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2352:Dnah11
|
UTSW |
12 |
117,892,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2410:Dnah11
|
UTSW |
12 |
117,991,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2885:Dnah11
|
UTSW |
12 |
117,951,162 (GRCm39) |
nonsense |
probably null |
|
|
R3499:Dnah11
|
UTSW |
12 |
117,874,758 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3741:Dnah11
|
UTSW |
12 |
118,095,076 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3742:Dnah11
|
UTSW |
12 |
118,095,076 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3779:Dnah11
|
UTSW |
12 |
118,094,448 (GRCm39) |
splice site |
probably benign |
|
|
R3785:Dnah11
|
UTSW |
12 |
117,981,337 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3883:Dnah11
|
UTSW |
12 |
117,942,188 (GRCm39) |
splice site |
probably benign |
|
|
R4014:Dnah11
|
UTSW |
12 |
117,938,649 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4043:Dnah11
|
UTSW |
12 |
117,843,678 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4072:Dnah11
|
UTSW |
12 |
118,070,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4073:Dnah11
|
UTSW |
12 |
118,009,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4074:Dnah11
|
UTSW |
12 |
118,009,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4076:Dnah11
|
UTSW |
12 |
118,009,413 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4201:Dnah11
|
UTSW |
12 |
117,930,394 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R4224:Dnah11
|
UTSW |
12 |
118,094,627 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4233:Dnah11
|
UTSW |
12 |
117,880,526 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4358:Dnah11
|
UTSW |
12 |
118,089,578 (GRCm39) |
nonsense |
probably null |
|
|
R4430:Dnah11
|
UTSW |
12 |
117,946,746 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4465:Dnah11
|
UTSW |
12 |
117,951,186 (GRCm39) |
missense |
probably benign |
0.09 |
|
R4489:Dnah11
|
UTSW |
12 |
117,880,631 (GRCm39) |
missense |
probably benign |
0.31 |
|
R4572:Dnah11
|
UTSW |
12 |
117,973,860 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4574:Dnah11
|
UTSW |
12 |
117,975,990 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4657:Dnah11
|
UTSW |
12 |
118,156,162 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4709:Dnah11
|
UTSW |
12 |
117,982,495 (GRCm39) |
missense |
probably benign |
0.26 |
|
R4740:Dnah11
|
UTSW |
12 |
118,084,279 (GRCm39) |
missense |
probably benign |
0.28 |
|
R4803:Dnah11
|
UTSW |
12 |
118,091,343 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4896:Dnah11
|
UTSW |
12 |
117,958,935 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4908:Dnah11
|
UTSW |
12 |
118,090,618 (GRCm39) |
missense |
probably benign |
0.37 |
|
R5018:Dnah11
|
UTSW |
12 |
118,094,463 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5071:Dnah11
|
UTSW |
12 |
118,046,188 (GRCm39) |
nonsense |
probably null |
|
|
R5074:Dnah11
|
UTSW |
12 |
118,046,188 (GRCm39) |
nonsense |
probably null |
|
|
R5080:Dnah11
|
UTSW |
12 |
118,162,565 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R5097:Dnah11
|
UTSW |
12 |
117,981,435 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5131:Dnah11
|
UTSW |
12 |
117,918,486 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5215:Dnah11
|
UTSW |
12 |
118,121,096 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5252:Dnah11
|
UTSW |
12 |
118,089,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5296:Dnah11
|
UTSW |
12 |
117,847,151 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5308:Dnah11
|
UTSW |
12 |
118,049,415 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5368:Dnah11
|
UTSW |
12 |
117,918,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5383:Dnah11
|
UTSW |
12 |
118,049,432 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5499:Dnah11
|
UTSW |
12 |
118,070,209 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R5503:Dnah11
|
UTSW |
12 |
117,844,186 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5546:Dnah11
|
UTSW |
12 |
117,939,583 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5578:Dnah11
|
UTSW |
12 |
117,982,537 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5657:Dnah11
|
UTSW |
12 |
117,847,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5702:Dnah11
|
UTSW |
12 |
118,077,642 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5706:Dnah11
|
UTSW |
12 |
117,987,670 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5727:Dnah11
|
UTSW |
12 |
118,090,841 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5737:Dnah11
|
UTSW |
12 |
118,156,125 (GRCm39) |
missense |
probably benign |
|
|
R5884:Dnah11
|
UTSW |
12 |
118,141,269 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5900:Dnah11
|
UTSW |
12 |
118,046,166 (GRCm39) |
splice site |
probably null |
|
|
R5905:Dnah11
|
UTSW |
12 |
117,918,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5928:Dnah11
|
UTSW |
12 |
117,878,371 (GRCm39) |
splice site |
probably null |
|
|
R5973:Dnah11
|
UTSW |
12 |
118,074,687 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6024:Dnah11
|
UTSW |
12 |
117,994,007 (GRCm39) |
missense |
probably benign |
0.34 |
|
R6056:Dnah11
|
UTSW |
12 |
117,892,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6075:Dnah11
|
UTSW |
12 |
118,068,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6092:Dnah11
|
UTSW |
12 |
117,892,191 (GRCm39) |
missense |
probably benign |
|
|
R6191:Dnah11
|
UTSW |
12 |
118,154,632 (GRCm39) |
missense |
probably benign |
|
|
R6197:Dnah11
|
UTSW |
12 |
118,143,482 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6262:Dnah11
|
UTSW |
12 |
117,894,913 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6321:Dnah11
|
UTSW |
12 |
118,106,027 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6454:Dnah11
|
UTSW |
12 |
117,880,590 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6614:Dnah11
|
UTSW |
12 |
117,850,411 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R6694:Dnah11
|
UTSW |
12 |
118,150,617 (GRCm39) |
splice site |
probably null |
|
|
R6712:Dnah11
|
UTSW |
12 |
118,014,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6720:Dnah11
|
UTSW |
12 |
118,009,381 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6742:Dnah11
|
UTSW |
12 |
118,077,629 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6806:Dnah11
|
UTSW |
12 |
117,951,411 (GRCm39) |
splice site |
probably null |
|
|
R6895:Dnah11
|
UTSW |
12 |
117,958,926 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6939:Dnah11
|
UTSW |
12 |
118,070,297 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6940:Dnah11
|
UTSW |
12 |
118,162,503 (GRCm39) |
missense |
probably benign |
|
|
R6945:Dnah11
|
UTSW |
12 |
118,024,045 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Dnah11
|
UTSW |
12 |
117,897,544 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6970:Dnah11
|
UTSW |
12 |
118,072,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6976:Dnah11
|
UTSW |
12 |
118,162,378 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7000:Dnah11
|
UTSW |
12 |
117,981,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7011:Dnah11
|
UTSW |
12 |
117,885,753 (GRCm39) |
frame shift |
probably null |
|
|
R7101:Dnah11
|
UTSW |
12 |
118,031,880 (GRCm39) |
missense |
probably benign |
|
|
R7106:Dnah11
|
UTSW |
12 |
117,924,884 (GRCm39) |
missense |
probably benign |
0.15 |
|
R7203:Dnah11
|
UTSW |
12 |
118,009,257 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7219:Dnah11
|
UTSW |
12 |
118,090,624 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7219:Dnah11
|
UTSW |
12 |
118,004,830 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7308:Dnah11
|
UTSW |
12 |
117,959,010 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7361:Dnah11
|
UTSW |
12 |
117,982,477 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7367:Dnah11
|
UTSW |
12 |
117,951,177 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R7399:Dnah11
|
UTSW |
12 |
118,089,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7399:Dnah11
|
UTSW |
12 |
117,991,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7404:Dnah11
|
UTSW |
12 |
118,068,543 (GRCm39) |
missense |
probably benign |
0.36 |
|
R7473:Dnah11
|
UTSW |
12 |
117,866,911 (GRCm39) |
missense |
probably benign |
0.19 |
|
R7545:Dnah11
|
UTSW |
12 |
117,894,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7608:Dnah11
|
UTSW |
12 |
118,104,505 (GRCm39) |
splice site |
probably null |
|
|
R7625:Dnah11
|
UTSW |
12 |
118,160,377 (GRCm39) |
missense |
probably benign |
|
|
R7761:Dnah11
|
UTSW |
12 |
117,987,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7879:Dnah11
|
UTSW |
12 |
118,004,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7881:Dnah11
|
UTSW |
12 |
117,951,237 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7904:Dnah11
|
UTSW |
12 |
117,867,003 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8100:Dnah11
|
UTSW |
12 |
117,930,368 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8179:Dnah11
|
UTSW |
12 |
117,842,284 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8192:Dnah11
|
UTSW |
12 |
117,976,181 (GRCm39) |
missense |
probably benign |
|
|
R8254:Dnah11
|
UTSW |
12 |
117,842,259 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8268:Dnah11
|
UTSW |
12 |
117,991,243 (GRCm39) |
nonsense |
probably null |
|
|
R8272:Dnah11
|
UTSW |
12 |
118,074,752 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8344:Dnah11
|
UTSW |
12 |
118,049,466 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8515:Dnah11
|
UTSW |
12 |
117,939,533 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8528:Dnah11
|
UTSW |
12 |
117,972,538 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8557:Dnah11
|
UTSW |
12 |
117,842,247 (GRCm39) |
missense |
probably benign |
|
|
R8676:Dnah11
|
UTSW |
12 |
118,154,539 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8738:Dnah11
|
UTSW |
12 |
118,049,384 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8773:Dnah11
|
UTSW |
12 |
117,958,950 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8818:Dnah11
|
UTSW |
12 |
117,874,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8855:Dnah11
|
UTSW |
12 |
118,156,107 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8866:Dnah11
|
UTSW |
12 |
118,156,107 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8881:Dnah11
|
UTSW |
12 |
118,090,550 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8881:Dnah11
|
UTSW |
12 |
118,077,647 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8920:Dnah11
|
UTSW |
12 |
118,077,674 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8944:Dnah11
|
UTSW |
12 |
118,091,381 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R8945:Dnah11
|
UTSW |
12 |
117,987,718 (GRCm39) |
missense |
probably benign |
0.36 |
|
R8962:Dnah11
|
UTSW |
12 |
117,918,630 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8962:Dnah11
|
UTSW |
12 |
117,916,273 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9059:Dnah11
|
UTSW |
12 |
118,094,578 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9155:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9162:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9164:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9171:Dnah11
|
UTSW |
12 |
117,894,918 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9186:Dnah11
|
UTSW |
12 |
118,154,632 (GRCm39) |
missense |
probably benign |
|
|
R9205:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9208:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9234:Dnah11
|
UTSW |
12 |
117,951,095 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9264:Dnah11
|
UTSW |
12 |
117,991,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9290:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9291:Dnah11
|
UTSW |
12 |
117,991,251 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9315:Dnah11
|
UTSW |
12 |
118,143,341 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9353:Dnah11
|
UTSW |
12 |
118,143,434 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9375:Dnah11
|
UTSW |
12 |
117,884,703 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9392:Dnah11
|
UTSW |
12 |
118,141,290 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9392:Dnah11
|
UTSW |
12 |
118,011,055 (GRCm39) |
nonsense |
probably null |
|
|
R9433:Dnah11
|
UTSW |
12 |
117,976,007 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9511:Dnah11
|
UTSW |
12 |
117,878,352 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9526:Dnah11
|
UTSW |
12 |
118,150,711 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9566:Dnah11
|
UTSW |
12 |
117,938,728 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9673:Dnah11
|
UTSW |
12 |
117,982,513 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9705:Dnah11
|
UTSW |
12 |
118,094,770 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9716:Dnah11
|
UTSW |
12 |
118,024,148 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9746:Dnah11
|
UTSW |
12 |
117,842,311 (GRCm39) |
nonsense |
probably null |
|
|
R9764:Dnah11
|
UTSW |
12 |
117,884,704 (GRCm39) |
missense |
probably benign |
0.05 |
|
RF023:Dnah11
|
UTSW |
12 |
117,918,585 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF047:Dnah11
|
UTSW |
12 |
117,973,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dnah11
|
UTSW |
12 |
117,858,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dnah11
|
UTSW |
12 |
117,946,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Dnah11
|
UTSW |
12 |
118,094,534 (GRCm39) |
missense |
probably damaging |
0.97 |
|
Z1176:Dnah11
|
UTSW |
12 |
118,090,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Dnah11
|
UTSW |
12 |
117,894,912 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
| Predicted Primers |
PCR Primer
(F):5'- CACATTGCTCACCTCAGGGCATAC -3'
(R):5'- CCATCCACCAAGGCTTCTCATTGAC -3'
Sequencing Primer
(F):5'- GGCATACGTCATCCTGTCAG -3'
(R):5'- CTGACCCTTAGTCTAAGCAGG -3'
|
| Posted On |
2014-05-23 |
Incidental Mutation