Mutagenetix > Incidental Mutation

Incidental Mutation 'R1466:Smarcc2'

201208

Institutional Source

Beutler Lab

Gene Symbol

Smarcc2

Ensembl Gene

ENSMUSG00000025369

Gene Name

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2

Synonyms

5930405J04Rik

Accession Numbers

Essential gene?

Probably essential (E-score: 0.841) question?

Stock #

R1466 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

128459248-128490482 bp(+) (GRCm38)

Type of Mutation

missense

DNA Base Change (assembly)

A to T at 128474245 bp (GRCm38)

Zygosity

Heterozygous

Amino Acid Change

Threonine to Serine at position 376 (T376S)

Ref Sequence

ENSEMBL: ENSMUSP00000096734 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000026433] [ENSMUST00000099131] [ENSMUST00000105235] [ENSMUST00000218228]

AlphaFold

Q6PDG5

Predicted Effect

possibly damaging
Transcript: ENSMUST00000026433
AA Change: T376S

PolyPhen 2 Score 0.901 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000026433
Gene: ENSMUSG00000025369
AA Change: T376S

Domain	Start	End	E-Value	Type
low complexity region	48	64	N/A	INTRINSIC
CHROMO	186	235	5.97e-6	SMART
low complexity region	297	307	N/A	INTRINSIC
Pfam:SWIRM	424	512	4.9e-38	PFAM
low complexity region	545	557	N/A	INTRINSIC
SANT	597	645	9.04e-12	SMART
low complexity region	768	816	N/A	INTRINSIC
low complexity region	861	879	N/A	INTRINSIC
coiled coil region	906	921	N/A	INTRINSIC
low complexity region	948	982	N/A	INTRINSIC
low complexity region	985	1010	N/A	INTRINSIC
low complexity region	1012	1062	N/A	INTRINSIC
low complexity region	1074	1098	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000099131
AA Change: T376S

PolyPhen 2 Score 0.984 (Sensitivity: 0.74; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000096734
Gene: ENSMUSG00000025369
AA Change: T376S

Domain	Start	End	E-Value	Type
low complexity region	48	64	N/A	INTRINSIC
CHROMO	186	235	5.97e-6	SMART
low complexity region	297	307	N/A	INTRINSIC
Pfam:SWIRM	424	512	3.9e-38	PFAM
SANT	628	676	9.04e-12	SMART
low complexity region	799	847	N/A	INTRINSIC
low complexity region	892	910	N/A	INTRINSIC
coiled coil region	937	952	N/A	INTRINSIC
low complexity region	979	1013	N/A	INTRINSIC
low complexity region	1016	1041	N/A	INTRINSIC
low complexity region	1043	1093	N/A	INTRINSIC
low complexity region	1105	1129	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000105235
AA Change: T376S

PolyPhen 2 Score 0.901 (Sensitivity: 0.82; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000100868
Gene: ENSMUSG00000025369
AA Change: T376S

Domain	Start	End	E-Value	Type
low complexity region	48	64	N/A	INTRINSIC
CHROMO	186	235	5.97e-6	SMART
low complexity region	297	307	N/A	INTRINSIC
Pfam:SWIRM	426	512	4.5e-35	PFAM
low complexity region	545	557	N/A	INTRINSIC
SANT	597	645	9.04e-12	SMART
Pfam:SWIRM-assoc_3	684	750	4.1e-34	PFAM
low complexity region	768	816	N/A	INTRINSIC
Pfam:SWIRM-assoc_1	863	946	1.5e-34	PFAM
low complexity region	948	982	N/A	INTRINSIC
low complexity region	985	1010	N/A	INTRINSIC
low complexity region	1012	1062	N/A	INTRINSIC
low complexity region	1077	1093	N/A	INTRINSIC
low complexity region	1108	1123	N/A	INTRINSIC
low complexity region	1153	1177	N/A	INTRINSIC
low complexity region	1184	1212	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000217751

Predicted Effect

probably benign
Transcript: ENSMUST00000218228

Coding Region Coverage

1x: 97.4%
3x: 96.7%
10x: 94.7%
20x: 90.4%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the SWI/SNF family of proteins, whose members display helicase and ATPase activities and which are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and contains a predicted leucine zipper motif typical of many transcription factors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for a targeted allele exhibit a slight increase in embryo weight at E13.5 and die shortly after birth (P0-P3). Mice homozygous for a conditional allele activated in the brain exhibit reduced cerebral cortical size and thickness. [provided by MGI curators]

Allele List at MGI

Other mutations in this stock

Total: 134 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1110012J17Rik	T	A	17: 66,380,435 (GRCm38)	D492V	probably damaging	Het
Abca13	T	C	11: 9,570,536 (GRCm38)		probably benign	Het
Abcg8	G	C	17: 84,686,727 (GRCm38)		probably benign	Het
Abhd15	C	T	11: 77,515,410 (GRCm38)	A71V	probably damaging	Het
AC167973.1	A	T	9: 43,265,352 (GRCm38)		noncoding transcript	Het
Adamts12	T	C	15: 11,311,359 (GRCm38)	F1234S	probably benign	Het
Ahnak	A	G	19: 9,015,875 (GRCm38)	D4841G	probably damaging	Het
Akap13	T	C	7: 75,729,049 (GRCm38)	S2095P	possibly damaging	Het
Ampd2	T	C	3: 108,080,337 (GRCm38)		probably null	Het
Arhgef17	G	T	7: 100,929,659 (GRCm38)	P694Q	possibly damaging	Het
Arrdc1	T	C	2: 24,925,795 (GRCm38)	I398V	probably benign	Het
Ash1l	T	C	3: 89,052,065 (GRCm38)	Y2250H	probably damaging	Het
Aspg	A	G	12: 112,121,852 (GRCm38)	N385D	probably benign	Het
Atxn3	G	A	12: 101,926,499 (GRCm38)	R319C	possibly damaging	Het
Brca2	G	A	5: 150,552,258 (GRCm38)	A2478T	probably damaging	Het
Btrc	T	A	19: 45,513,382 (GRCm38)		probably benign	Het
C1s1	C	T	6: 124,531,131 (GRCm38)	C633Y	probably damaging	Het
C8g	C	T	2: 25,500,216 (GRCm38)	A6T	probably benign	Het
Capza2	T	C	6: 17,657,159 (GRCm38)		probably benign	Het
Cbl	A	T	9: 44,154,244 (GRCm38)	V706E	probably benign	Het
Ccdc121rt3	C	T	5: 112,354,764 (GRCm38)	G358D	probably benign	Het
Cenatac	A	T	9: 44,413,680 (GRCm38)		probably benign	Het
Cfhr1	C	T	1: 139,557,574 (GRCm38)	E45K	probably benign	Het
Chd7	G	A	4: 8,840,561 (GRCm38)		probably null	Het
Chek1	G	T	9: 36,725,857 (GRCm38)	A2E	probably damaging	Het
Clcn2	G	A	16: 20,712,552 (GRCm38)		probably benign	Het
Cndp2	G	A	18: 84,677,315 (GRCm38)		probably benign	Het
Cntnap1	C	A	11: 101,180,360 (GRCm38)	F366L	probably damaging	Het
Col5a1	G	T	2: 28,003,846 (GRCm38)		probably benign	Het
Corin	C	T	5: 72,302,790 (GRCm38)		probably null	Het
Crb2	T	C	2: 37,783,388 (GRCm38)	Y99H	probably damaging	Het
Csf3r	T	A	4: 126,031,932 (GRCm38)		probably benign	Het
Ctdspl2	G	A	2: 122,003,929 (GRCm38)	R332K	probably benign	Het
Ctnnbl1	C	T	2: 157,799,417 (GRCm38)		probably benign	Het
Cym	G	A	3: 107,213,458 (GRCm38)	T277I	probably damaging	Het
Cyp2d11	C	T	15: 82,391,735 (GRCm38)	C215Y	probably benign	Het
Dido1	G	A	2: 180,662,328 (GRCm38)	P1261L	probably damaging	Het
Dnah10	T	A	5: 124,763,096 (GRCm38)	Y1265N	probably benign	Het
Dtx3l	G	A	16: 35,932,728 (GRCm38)	L503F	probably damaging	Het
Eda	T	A	X: 100,392,392 (GRCm38)		probably benign	Homo
Efhb	A	G	17: 53,437,178 (GRCm38)	F462L	probably damaging	Het
Enpep	T	A	3: 129,319,448 (GRCm38)	T203S	probably damaging	Het
Exd1	G	A	2: 119,520,734 (GRCm38)		probably benign	Het
Fam184b	G	A	5: 45,580,509 (GRCm38)		probably benign	Het
Fam20b	T	C	1: 156,686,188 (GRCm38)		probably benign	Het
Fat3	A	C	9: 16,375,482 (GRCm38)	V915G	probably damaging	Het
Fbln7	A	G	2: 128,877,429 (GRCm38)	T49A	probably benign	Het
Fcho1	C	T	8: 71,712,560 (GRCm38)	A418T	probably benign	Het
Fgf14	T	A	14: 124,676,539 (GRCm38)	K60M	probably benign	Het
Galnt4	A	G	10: 99,108,709 (GRCm38)	R99G	probably benign	Het
Gimap4	C	A	6: 48,691,282 (GRCm38)	Q196K	probably benign	Het
Glcci1	C	T	6: 8,537,964 (GRCm38)	T6I	probably damaging	Het
Gm10110	A	T	14: 89,898,075 (GRCm38)		noncoding transcript	Het
Gm4884	A	G	7: 41,043,128 (GRCm38)	K174E	probably damaging	Het
Grip2	A	T	6: 91,788,443 (GRCm38)	D19E	probably damaging	Het
Grk4	T	C	5: 34,694,750 (GRCm38)	S113P	probably benign	Het
Hectd3	G	A	4: 116,996,566 (GRCm38)	E220K	probably damaging	Het
Helz2	G	A	2: 181,236,297 (GRCm38)	P903S	probably damaging	Het
Hydin	T	A	8: 110,532,953 (GRCm38)	V2519E	possibly damaging	Het
Igf2r	A	T	17: 12,717,269 (GRCm38)		probably benign	Het
Ints11	G	A	4: 155,888,110 (GRCm38)		probably null	Het
Kif1a	A	G	1: 93,054,929 (GRCm38)	W718R	possibly damaging	Het
Kif1b	A	T	4: 149,223,252 (GRCm38)	Y839N	probably damaging	Het
Kif20b	T	A	19: 34,950,599 (GRCm38)	V1047D	probably benign	Het
Klhl23	T	C	2: 69,833,888 (GRCm38)	I527T	probably damaging	Het
Klra10	T	C	6: 130,279,431 (GRCm38)	N87D	probably damaging	Het
Klra10	T	A	6: 130,279,315 (GRCm38)	R125S	probably damaging	Het
Lars1	G	A	18: 42,210,050 (GRCm38)	R1101C	probably damaging	Het
Lcn4	G	A	2: 26,668,576 (GRCm38)	P166L	probably damaging	Het
Letmd1	T	A	15: 100,472,542 (GRCm38)		probably null	Het
Lrrc27	A	G	7: 139,230,308 (GRCm38)		probably benign	Het
Map4k2	G	T	19: 6,341,917 (GRCm38)	W87L	probably damaging	Het
Mccc1	A	G	3: 35,974,286 (GRCm38)	V457A	probably benign	Het
Mdn1	T	A	4: 32,730,788 (GRCm38)	S2886T	probably benign	Het
Mgat4a	A	T	1: 37,464,406 (GRCm38)		probably benign	Het
Mmp1b	A	T	9: 7,384,779 (GRCm38)		probably benign	Het
Mroh2b	G	T	15: 4,925,684 (GRCm38)	D720Y	probably damaging	Het
Mrpl24	T	A	3: 87,921,928 (GRCm38)	Y21*	probably null	Het
Mrps35	C	T	6: 147,055,984 (GRCm38)	T169M	probably damaging	Het
Muc2	A	G	7: 141,748,974 (GRCm38)	Y457C	probably damaging	Het
Muc4	G	A	16: 32,753,595 (GRCm38)	G1157D	probably benign	Het
Myg1	T	A	15: 102,337,390 (GRCm38)	L275Q	probably damaging	Het
Naga	T	A	15: 82,334,788 (GRCm38)	M237L	probably null	Het
Nek1	C	T	8: 61,125,136 (GRCm38)		probably benign	Het
Oc90	T	A	15: 65,897,720 (GRCm38)	Y96F	probably damaging	Het
Or12d13	A	T	17: 37,336,956 (GRCm38)	L92H	probably benign	Het
Or13a18	A	G	7: 140,610,969 (GRCm38)	I268V	probably benign	Het
Or4a80	C	T	2: 89,752,267 (GRCm38)	C187Y	probably damaging	Het
Or5m11b	T	A	2: 85,975,995 (GRCm38)	F251I	probably damaging	Het
Or6ae1	A	G	7: 140,162,203 (GRCm38)	V249A	probably damaging	Het
Orc4	A	T	2: 48,909,494 (GRCm38)	C324S	possibly damaging	Het
Pald1	T	C	10: 61,348,525 (GRCm38)		probably benign	Het
Paox	A	G	7: 140,129,281 (GRCm38)		probably benign	Het
Pcdh10	T	G	3: 45,379,974 (GRCm38)	L241R	probably damaging	Het
Pdzrn4	T	C	15: 92,770,537 (GRCm38)	S857P	probably benign	Het
Plec	C	T	15: 76,185,908 (GRCm38)	E1000K	possibly damaging	Het
Plvap	A	T	8: 71,508,481 (GRCm38)	V149D	probably benign	Het
Ppef1	C	A	X: 160,625,674 (GRCm38)		probably null	Homo
Prkaa1	C	A	15: 5,178,798 (GRCm38)	P507T	probably benign	Het
Psmd2	A	G	16: 20,657,965 (GRCm38)		probably benign	Het
Ptch1	A	G	13: 63,524,969 (GRCm38)	Y804H	probably benign	Het
R3hdm2	A	G	10: 127,476,690 (GRCm38)	I434V	probably benign	Het
Rbm28	G	A	6: 29,155,017 (GRCm38)		probably benign	Het
Rfx5	T	A	3: 94,956,303 (GRCm38)	Y88N	probably damaging	Het
Rnase2b	A	T	14: 51,162,839 (GRCm38)	K126*	probably null	Het
Rpl3l	A	G	17: 24,730,871 (GRCm38)	I15V	probably benign	Het
Saal1	G	T	7: 46,702,545 (GRCm38)		probably null	Het
Sbpl	A	C	17: 23,953,254 (GRCm38)	D230E	unknown	Het
Scn10a	T	C	9: 119,666,490 (GRCm38)	Y322C	probably damaging	Het
Sec16a	A	T	2: 26,431,157 (GRCm38)	Y1308N	probably damaging	Het
Sis	A	T	3: 72,932,060 (GRCm38)	D824E	possibly damaging	Het
Slc25a36	A	G	9: 97,080,355 (GRCm38)	F194L	probably damaging	Het
Slc27a4	T	A	2: 29,811,190 (GRCm38)	V331E	probably damaging	Het
Slc7a11	G	T	3: 50,381,073 (GRCm38)		probably null	Het
Slco4c1	A	T	1: 96,841,172 (GRCm38)	S322T	probably damaging	Het
Srebf1	C	T	11: 60,200,702 (GRCm38)	R999H	probably benign	Het
St3gal3	A	C	4: 118,107,662 (GRCm38)	M1R	probably null	Het
Syp	A	T	X: 7,648,705 (GRCm38)		probably benign	Homo
Tas1r2	A	G	4: 139,669,411 (GRCm38)	D687G	probably damaging	Het
Tekt4	A	T	17: 25,472,074 (GRCm38)	Q118L	probably benign	Het
Thoc2l	T	A	5: 104,518,257 (GRCm38)	I215N	probably damaging	Het
Tph2	T	C	10: 115,079,695 (GRCm38)	N480S	probably benign	Het
Tsc2	A	T	17: 24,608,973 (GRCm38)	M839K	probably damaging	Het
Ttc22	T	C	4: 106,622,780 (GRCm38)	F77S	probably damaging	Het
Uaca	C	T	9: 60,854,321 (GRCm38)	A205V	possibly damaging	Het
Ubp1	T	G	9: 113,944,835 (GRCm38)		probably benign	Het
Uhmk1	A	T	1: 170,208,653 (GRCm38)		probably null	Het
Usp17lc	A	G	7: 103,418,941 (GRCm38)	H481R	possibly damaging	Het
Vwa3a	A	G	7: 120,768,165 (GRCm38)	Y181C	probably damaging	Het
Wdr26	C	T	1: 181,185,934 (GRCm38)		probably benign	Het
Wfikkn2	G	A	11: 94,238,895 (GRCm38)	T140I	probably damaging	Het
Zfp704	G	T	3: 9,447,348 (GRCm38)	T288N	possibly damaging	Het
Zfp93	T	C	7: 24,276,096 (GRCm38)	V502A	probably damaging	Het
Zzef1	C	T	11: 72,924,679 (GRCm38)	P2942S	probably damaging	Het

Other mutations in Smarcc2

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00496:Smarcc2	APN	10	128,463,055 (GRCm38)	missense	probably damaging	0.97
IGL01450:Smarcc2	APN	10	128,469,320 (GRCm38)	missense	probably damaging	1.00
IGL01638:Smarcc2	APN	10	128,488,074 (GRCm38)	unclassified	probably benign
IGL01663:Smarcc2	APN	10	128,488,977 (GRCm38)	unclassified	probably benign
IGL02308:Smarcc2	APN	10	128,482,772 (GRCm38)	missense	probably damaging	1.00
IGL02511:Smarcc2	APN	10	128,461,382 (GRCm38)	missense	probably damaging	1.00
IGL02633:Smarcc2	APN	10	128,469,687 (GRCm38)	missense	probably damaging	1.00
IGL03375:Smarcc2	APN	10	128,482,912 (GRCm38)	missense	probably damaging	0.99
IGL03493:Smarcc2	APN	10	128,461,357 (GRCm38)	missense	probably damaging	1.00
PIT4403001:Smarcc2	UTSW	10	128,463,024 (GRCm38)	missense	probably damaging	1.00
R0220:Smarcc2	UTSW	10	128,483,636 (GRCm38)	missense	probably benign	0.32
R0281:Smarcc2	UTSW	10	128,474,722 (GRCm38)	missense	probably benign	0.20
R1299:Smarcc2	UTSW	10	128,461,378 (GRCm38)	missense	probably damaging	1.00
R1447:Smarcc2	UTSW	10	128,469,791 (GRCm38)	critical splice donor site	probably null
R1466:Smarcc2	UTSW	10	128,474,245 (GRCm38)	missense	probably damaging	0.98
R1498:Smarcc2	UTSW	10	128,482,192 (GRCm38)	missense	probably benign	0.02
R1499:Smarcc2	UTSW	10	128,463,872 (GRCm38)	missense	probably damaging	0.99
R1616:Smarcc2	UTSW	10	128,482,793 (GRCm38)	missense	probably damaging	1.00
R1718:Smarcc2	UTSW	10	128,468,998 (GRCm38)	intron	probably benign
R1767:Smarcc2	UTSW	10	128,469,082 (GRCm38)	missense	possibly damaging	0.92
R1792:Smarcc2	UTSW	10	128,463,871 (GRCm38)	missense	probably damaging	1.00
R1965:Smarcc2	UTSW	10	128,474,758 (GRCm38)	missense	probably damaging	1.00
R2229:Smarcc2	UTSW	10	128,488,341 (GRCm38)	unclassified	probably benign
R2286:Smarcc2	UTSW	10	128,463,743 (GRCm38)	missense	possibly damaging	0.58
R2367:Smarcc2	UTSW	10	128,482,167 (GRCm38)	missense	possibly damaging	0.86
R2398:Smarcc2	UTSW	10	128,469,682 (GRCm38)	missense	possibly damaging	0.92
R3084:Smarcc2	UTSW	10	128,488,159 (GRCm38)	unclassified	probably benign
R3085:Smarcc2	UTSW	10	128,488,159 (GRCm38)	unclassified	probably benign
R3777:Smarcc2	UTSW	10	128,482,943 (GRCm38)	critical splice donor site	probably null
R4346:Smarcc2	UTSW	10	128,468,823 (GRCm38)	missense	probably benign	0.02
R4967:Smarcc2	UTSW	10	128,483,180 (GRCm38)	missense	probably damaging	0.99
R4992:Smarcc2	UTSW	10	128,474,710 (GRCm38)	missense	probably damaging	0.99
R5028:Smarcc2	UTSW	10	128,461,445 (GRCm38)	missense	probably damaging	0.99
R5071:Smarcc2	UTSW	10	128,463,940 (GRCm38)	missense	probably damaging	1.00
R5095:Smarcc2	UTSW	10	128,469,300 (GRCm38)	missense	probably damaging	0.99
R5133:Smarcc2	UTSW	10	128,461,473 (GRCm38)	critical splice donor site	probably null
R5180:Smarcc2	UTSW	10	128,487,362 (GRCm38)	unclassified	probably benign
R5231:Smarcc2	UTSW	10	128,461,352 (GRCm38)	missense	probably damaging	1.00
R5240:Smarcc2	UTSW	10	128,481,006 (GRCm38)	critical splice donor site	probably null
R5401:Smarcc2	UTSW	10	128,465,504 (GRCm38)	missense	probably damaging	1.00
R5445:Smarcc2	UTSW	10	128,488,074 (GRCm38)	unclassified	probably benign
R5690:Smarcc2	UTSW	10	128,484,407 (GRCm38)	missense	probably damaging	1.00
R5694:Smarcc2	UTSW	10	128,484,127 (GRCm38)	missense	probably benign
R6240:Smarcc2	UTSW	10	128,488,024 (GRCm38)	unclassified	probably benign
R6545:Smarcc2	UTSW	10	128,484,128 (GRCm38)	missense	probably benign	0.00
R6713:Smarcc2	UTSW	10	128,487,769 (GRCm38)	splice site	probably null
R6934:Smarcc2	UTSW	10	128,469,672 (GRCm38)	missense	probably benign	0.27
R7016:Smarcc2	UTSW	10	128,485,329 (GRCm38)	splice site	probably null
R7149:Smarcc2	UTSW	10	128,482,729 (GRCm38)	missense	probably damaging	1.00
R7229:Smarcc2	UTSW	10	128,488,048 (GRCm38)	missense	unknown
R7395:Smarcc2	UTSW	10	128,485,606 (GRCm38)	missense	probably damaging	1.00
R7596:Smarcc2	UTSW	10	128,482,793 (GRCm38)	missense	probably damaging	1.00
R7722:Smarcc2	UTSW	10	128,481,728 (GRCm38)	missense	possibly damaging	0.72
R8407:Smarcc2	UTSW	10	128,482,321 (GRCm38)	missense	probably damaging	1.00
R8468:Smarcc2	UTSW	10	128,484,393 (GRCm38)	missense	probably benign	0.00
R8753:Smarcc2	UTSW	10	128,483,201 (GRCm38)	missense	probably damaging	1.00
R9023:Smarcc2	UTSW	10	128,465,224 (GRCm38)	missense	probably damaging	0.98
R9325:Smarcc2	UTSW	10	128,488,207 (GRCm38)	missense	unknown
R9327:Smarcc2	UTSW	10	128,485,617 (GRCm38)	missense	probably damaging	1.00
R9331:Smarcc2	UTSW	10	128,487,441 (GRCm38)	missense	unknown
R9686:Smarcc2	UTSW	10	128,480,906 (GRCm38)	missense	probably damaging	1.00
R9742:Smarcc2	UTSW	10	128,461,353 (GRCm38)	missense	probably damaging	1.00
Z1088:Smarcc2	UTSW	10	128,461,434 (GRCm38)	missense	probably damaging	1.00

Predicted Primers

PCR Primer
(F):5'- ACGCACATAGATGCTGGGCAAG -3'
(R):5'- AACACTGTGATCCCTGTCCCAGAG -3'

Sequencing Primer
(F):5'- TGCTGGGCAAGGCAGTAG -3'
(R):5'- GGTGGAGCCTCTCTAAGCTAATC -3'

Posted On

2014-05-23